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Journal Article
Nature Communications, ISSN 2041-1723, 01/2015, Volume 6, Issue 1, pp. 6087 - 6087
Journal Article
Gut, ISSN 0017-5749, 03/2017, Volume 66, Issue 3, pp. 530 - 540
ObjectiveSorafenib is effective in hepatocellular carcinoma (HCC), but patients ultimately present disease progression. Molecular mechanisms underlying... 
molecular genetics | stem cells | Hepatocellular carcinoma | molecular mechanisms | drug resistance | GROWTH-FACTOR RECEPTOR | CLASSIFICATION | ACTIVATION | INHIBITION | GASTROENTEROLOGY & HEPATOLOGY | MUTATION | Niacinamide - analogs & derivatives | Humans | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Fibroblast Growth Factors - genetics | Drug Resistance, Neoplasm | Male | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Fibroblast Growth Factors - metabolism | Carcinoma, Hepatocellular - drug therapy | Somatomedins - antagonists & inhibitors | Female | Liver Neoplasms - pathology | Spheroids, Cellular | Somatomedins - metabolism | Gene Expression | Signal Transduction | Liver Neoplasms - drug therapy | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Survival Rate | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Disease Progression | Xenograft Model Antitumor Assays | Animals | Receptors, Somatomedin - metabolism | Somatomedins - genetics | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Aged | Mice | Mice, Inbred BALB C | Fibroblast Growth Factors - antagonists & inhibitors | Receptors, Somatomedin - antagonists & inhibitors | Carcinoma, Hepatocellular - metabolism | Fibroblast growth factors | Hepatoma | Research | Insulin-like growth factor 1 | Index Medicus | Abridged Index Medicus | Liver cancer | Càncer de fetge | Antineoplastic agents | Medicaments antineoplàstics
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2011, Volume 140, Issue 5, pp. 1501 - 1512.e2
Journal Article
Gastroenterology, ISSN 0016-5085, 2013, Volume 144, Issue 4, pp. 829 - 840
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7516, pp. 110 - 114
Mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 are among the most common genetic alterations in intrahepatic cholangiocarcinoma (IHCC), a deadly liver... 
PROGENITORS | INTRAHEPATIC CHOLANGIOCARCINOMA | HOMEOSTASIS | LIVER-REGENERATION | MULTIDISCIPLINARY SCIENCES | MUTATION | GROWTH | MICE | PROLIFERATION | EXPRESSION | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Hepatocyte Nuclear Factor 4 - antagonists & inhibitors | Humans | ras Proteins - metabolism | Hepatocytes - pathology | Male | Hepatocytes - metabolism | Bile Duct Neoplasms - enzymology | Cell Differentiation - genetics | Neoplasm Metastasis | Hepatocyte Nuclear Factor 4 - biosynthesis | Female | Bile Duct Neoplasms - genetics | Cell Lineage - genetics | Cholangiocarcinoma - enzymology | Disease Models, Animal | Cell Division - genetics | Proto-Oncogene Proteins - metabolism | Hepatocyte Nuclear Factor 4 - metabolism | Bile Ducts, Intrahepatic - pathology | Mutant Proteins - genetics | Isocitrate Dehydrogenase - genetics | Mice, Transgenic | Mutant Proteins - metabolism | Proto-Oncogene Proteins - genetics | Hepatocyte Nuclear Factor 4 - genetics | Mutation - genetics | Bile Ducts, Intrahepatic - enzymology | Cholangiocarcinoma - pathology | Animals | Cholangiocarcinoma - genetics | Stem Cells - pathology | Isocitrate Dehydrogenase - metabolism | Glutarates - metabolism | Mice | Bile Duct Neoplasms - pathology | Hepatocytes - enzymology | Index Medicus | Càncer | Diferenciació cel·lular | Gallbladder diseases | Metabolisme | Cell diferentiation | Metabolism | Malalties de la vesícula biliar | Cancer
Journal Article
Hepatology, ISSN 0270-9139, 11/2012, Volume 56, Issue 5, pp. 1998 - 2000
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 4, pp. 806 - 818.e10
Journal Article