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JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, ISSN 1940-087X, 07/2019, Issue 149
Measurement of animal locomotion is a common behavioral tool used to describe the phenotype of a given disease, injury, or drug model. The low-cost method of... 
mouse models | neurodegenerative disease | NEUROCHEMICAL DEFICITS | ABNORMALITIES | MULTIDISCIPLINARY SCIENCES | footprint analysis | neuromuscular disease | phenotyping | gait analysis | RODENT MODELS | Issue 149 | stride length | MICE | Behavior | HUNTINGTONS-DISEASE | MOTOR DEFICITS | Index Medicus
Journal Article
Journal Article
Nature neuroscience, ISSN 1097-6256, 9/2014, Volume 17, Issue 9, pp. 1180 - 1189
Macroautophagy (hereafter autophagy) is a key pathway in neurodegeneration. Despite protective actions, autophagy may contribute to neuron demise, when... 
Journal Article
Drug discovery today, ISSN 1359-6446, 7/2014, Volume 19, Issue 7, pp. 963 - 971
Autophagy is the cellular process by which proteins, macromolecules, and organelles are targeted to and degraded by the lysosome. Given that neurodegenerative... 
Journal Article
Journal of Neuroscience, ISSN 1529-2401, 09/2012, Volume 32, Issue 36, pp. 12396 - 12405
Autophagy is a cell survival response to nutrient deprivation that delivers cellular components to lysosomes for digestion. In recent years, autophagy has also... 
Journal Article
Neuron, ISSN 0896-6273, 04/2014, Volume 82, Issue 2, pp. 295 - 307
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 01/2019, Volume 123, pp. 258 - 267
models of the intestinal barrier are being increasingly used to evaluate nanoparticles (NPs) exposure risk. Nevertheless, most of these studies have focused on... 
Translocation | Exposure time | Silver nanoparticles | Uptake | Barrier integrity | Caco-2/HT29 cocultures | CELLS | MODELS | FOOD SCIENCE & TECHNOLOGY | TOXICOLOGY | ABSORPTION | Index Medicus
Journal Article
Journal Article
International Journal of Cell Biology, ISSN 1687-8876, 2013, Volume 2013, pp. 560421 - 18
Prion diseases are linked to the accumulation of a misfolded isoform (PrP(Sc)) of prion protein (PrP). Evidence suggests that lysosomes are degradation... 
Lysosomes | Autophagy (Cytology) | Protein folding | Identification and classification | Endoplasmic reticulum | Health aspects | Proteins | Neurosciences | Prions | Creutzfeldt-Jakob disease | Colleges & universities | Quality control | Autophagy
Journal Article
Neuron, ISSN 0896-6273, 4/2014, Volume 82, Issue 2, pp. 295 - 307
X-linked spinal & bulbar muscular atrophy (SBMA) is characterized by adult-onset muscle weakness and lower motor neuron degeneration. SBMA is caused by... 
Journal Article