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Biochemical journal, ISSN 0264-6021, 07/2009, Volume 421, Issue 1, pp. 29 - 42
mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC (protein kinase A/protein kinase G/protein... 
Phosphoinositide 3-kinase (PI3K) | Akt/protein kinase B (PKB) | Serum and glucocorticoid protein kinase (SGK) | P70 ribosomal S6 kinase (S6K) | Kinase inhibitor | Cancer | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cell Line | Humans | Multiprotein Complexes | Morpholines - pharmacology | Transcription Factors - antagonists & inhibitors | Gene Expression Profiling | G1 Phase - drug effects | Pyrimidines - pharmacology | Morpholines - chemistry | Pyrimidines - chemistry | Mechanistic Target of Rapamycin Complex 1 | Gene Expression Regulation - drug effects | Proteins | Transcription Factors - metabolism | Animals | Fibroblasts - drug effects | Cell Proliferation - drug effects | Mice | TOR Serine-Threonine Kinases | Fibroblasts - metabolism | Index Medicus | PI3K, phosphoinositide 3-kinase | PDK, 3-phosphoinositide-dependent protein kinase | AMPK, AMP-activated protein kinase | mTORC, mTOR complex | DTT, dithiothreitol | phosphoinositide 3-kinase (PI3K) | p70 ribosomal S6 kinase (S6K) | SPHK, sphingosine kinase | ERK, extracellular-signal-regulated kinase | RSK, ribosomal S6 kinase | PH domain, pleckstrin homology domain | protein kinase B (PKB) | protein kinase G | NDRG1, N-Myc downstream-regulated gene-1 | IGF, insulin-like growth factor | mTOR, mammalian target of rapamycin | GST, glutathione transferase | SGK, serum and glucocorticoid protein kinase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | eIF4E, eukaryotic initiation factor 4E | 4E-BP1, eIF4E-binding protein 1 | protein kinase C family | Akt | PRAS40, proline-rich Akt substrate of 40 kDa | HEK-293 cell, human embryonic kidney 293 cell | kinase inhibitor | MEF, mouse embryonic fibroblast | AGC family, protein kinase A | cancer | serum and glucocorticoid protein kinase (SGK) | MAPK, mitogen-activated protein kinase
Journal Article
Nature (London), ISSN 1476-4687, 05/2016, Volume 534, Issue 7606, pp. 272 - 276
Journal Article
Clinical cancer research, ISSN 1078-0432, 03/2019, Volume 25, Issue 5, pp. 1574 - 1587
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 69, pp. 113874 - 113884
Activation of the PI3K/mTOR pathway has been shown to be correlated with resistance to chemotherapy in ovarian cancer. We aimed to investigate the effects of... 
Chemo-resistance | AZD2014 | Vistusertib | mTORC1/2 | Ovarian cancer | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology
Journal Article
Breast cancer research : BCR, ISSN 1465-542X, 12/2019, Volume 21, Issue 1, pp. 135 - 135
...-Joubert[sup.2] , Lila Zabaglo[sup.1] , Margaret Hills[sup.3] , Andrew Dodson[sup.3] , Qiong Gao[sup.1] , Stephen R. Johnston[sup.4] , Mitch Dowsett[sup.3] , Sabina C... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Care and treatment | Breast cancer | Analysis | Estrogen | Fulvestrant | Index Medicus | Endocrine resistance | Vistusertib | 2 signalling | mTORC1 | Oestrogen receptor | mTORC1/2 signalling
Journal Article
Molecular cancer therapeutics, ISSN 1535-7163, 01/2015, Volume 14, Issue 1, pp. 48 - 58
Journal Article