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Journal of Cellular Physiology, ISSN 0021-9541, 07/2018, Volume 233, Issue 7, pp. 5396 - 5404
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 10/2013, Volume 127, Issue 1, pp. 22 - 35
Transcriptional dysregulation is a hallmark of Huntington's disease (HD) and one cause of this dysregulation is enhanced activity of the REST‐ mSIN 3a‐ mSIN... 
protein–protein interaction | virtual drug screening | REST | NRSF | Huntington's disease | BDNF | REST/NRSF | protein-protein interaction | Huntington's disease (HD) | NEUROTROPHIC FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | NEURAL STEM-CELLS | TARGET GENES | RESTRICTIVE SILENCER FACTOR | DOWN-SYNDROME | FACTOR OCCUPANCY | INHIBITORS | DEACETYLASE COMPLEX | EXPRESSION | Immunohistochemistry | RNA, Small Interfering - genetics | Cell Proliferation | Luciferases - metabolism | Humans | RNA, Messenger - biosynthesis | Transfection | Chromatin Immunoprecipitation | RNA, Messenger - administration & dosage | Nerve Tissue Proteins - biosynthesis | Polymerase Chain Reaction | Brain-Derived Neurotrophic Factor - metabolism | Repressor Proteins - metabolism | Enzyme-Linked Immunosorbent Assay | Microinjections | Animals, Genetically Modified | RNA, Messenger - genetics | Cells, Cultured | Models, Molecular | Repressor Proteins - genetics | Zebrafish | Huntington Disease - metabolism | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Huntingtin Protein | Transcription, Genetic - physiology | Animals | Embryo, Nonmammalian | Huntington Disease - genetics | Transcription, Genetic - genetics | Co-Repressor Proteins | Genetic aspects | Models | Chemical properties | Genetic transcription | Neurons | Neurochemistry | Huntingtons disease | Molecules | Brain-derived neurotrophic factor | Binding sites | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e53748
Journal Article
Nature Neuroscience, ISSN 1097-6256, 05/2012, Volume 15, Issue 5, pp. 713 - 721
The Huntington's disease gene product, huntingtin, is indispensable for neural tube formation, but its role is obscure. We studied neurulation in htt-null... 
TARGETED DISRUPTION | ZEBRAFISH | LACKING HUNTINGTIN | EMBRYONIC STEM-CELLS | MUTANT HUNTINGTIN | ADAM10 | MICE | DISEASE GENE HOMOLOG | WILD-TYPE HUNTINGTIN | NEUROSCIENCES | N-CADHERIN CLEAVAGE | Body Patterning - drug effects | Guanylate Kinases - genetics | Amyloid Precursor Protein Secretases - genetics | RNA, Small Interfering - genetics | Wnt1 Protein - genetics | Brain - embryology | PAX2 Transcription Factor - metabolism | Cadherins - metabolism | Apoptosis - drug effects | Embryo, Mammalian | Hedgehog Proteins - metabolism | Apoptosis - genetics | Green Fluorescent Proteins - genetics | Brain - metabolism | NFI Transcription Factors - metabolism | Cadherins - genetics | Tissue Inhibitor of Metalloproteinase-1 - pharmacology | Discs Large Homolog 1 Protein | Membrane Proteins - genetics | Gene Expression Regulation, Developmental - drug effects | PAX2 Transcription Factor - genetics | Cell Adhesion - drug effects | Mutation - genetics | Biological Evolution | Brain - drug effects | Huntingtin Protein | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Analysis of Variance | Membrane Proteins - antagonists & inhibitors | Cell Adhesion - physiology | Embryo, Nonmammalian | Guanylate Kinases - metabolism | Neuroepithelial Cells - physiology | Mice | Zebrafish Proteins - genetics | ADAM Proteins - genetics | Cerebral Ventricles - cytology | Drosophila melanogaster | Neuroepithelial Cells - drug effects | Embryonic Stem Cells - metabolism | Nestin | Immunoprecipitation | Gene Expression Regulation, Developmental - genetics | Wnt1 Protein - metabolism | Zebrafish - embryology | Cell Differentiation - genetics | Transfection | Hedgehog Proteins - genetics | Intermediate Filament Proteins - genetics | Neurons - physiology | Membrane Proteins - metabolism | Cerebral Ventricles - embryology | Neurons - drug effects | Nuclear Proteins - genetics | Hydroxamic Acids - pharmacology | Green Fluorescent Proteins - metabolism | Brain - cytology | ADAM Proteins - antagonists & inhibitors | Animals, Genetically Modified | Zebrafish Proteins - metabolism | Dipeptides - pharmacology | Cells, Cultured | ADAM10 Protein | Morpholines - pharmacology | Nuclear Proteins - metabolism | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Dictyostelium | Embryonic Stem Cells - drug effects | Cell Differentiation - drug effects | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Body Patterning - genetics | Huntington's chorea | Physiological aspects | Cadherins | Genetic aspects | Research | Embryonic stem cells | Risk factors
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 02/2018, Volume 233, Issue 2, pp. 1455 - 1467
We have identified in zebrafish, that the transmembrane protein Tmem230a is a novel regulator of angiogenesis by its capacity to regulate the number of the... 
Delta/Notch signaling | blood vessel formation growth | Vegf signaling | angiogenesis | transmembrane protein 230 | PHYSIOLOGY | EPHRIN-B2 | NOTCH | CELL BIOLOGY | DLL4 | ARTERIES | Delta | Notch signaling | SPADETAIL | IN-VIVO | NETWORK FORMATION | EMBRYONIC VASCULAR DEVELOPMENT | KNOCKDOWN | EXPRESSION | Amino Acid Sequence | Cell Proliferation | Signal Transduction | Animals, Genetically Modified | Endothelial Cells - metabolism | Membrane Proteins - genetics | Receptors, Notch - metabolism | Zebrafish Proteins - metabolism | Receptors, Notch - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Zebrafish - embryology | Zebrafish - genetics | Animals | Gene Expression Regulation, Developmental | Base Sequence | Zebrafish - metabolism | Conserved Sequence | Membrane Proteins - metabolism | Zebrafish Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Neovascularization, Physiologic | Embryonic development | Drug discovery | Endothelial growth factors | Endothelium | Cell proliferation | Network formation | Leukocyte migration | Blood vessels | Zebrafish | Gene expression | Arteries | Endothelial cells | Regeneration (physiology) | Embryonic growth stage | Angiogenesis | Regeneration | Signal transduction | Signaling | Embryogenesis | Conserved sequence | Cell number | Notch protein | Aberration | Vascular endothelial growth factor | Cell migration
Journal Article
Journal Article