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1. Full Text Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
by Olldashi, Fatos and Kerçi, Mihal and Zhurda, Tefik and Ruçi, Klotilda and Banushi, Arben and Traverso, Mario Sardón and Jiménez, Juan and Balbi, Jorge and Dellera, Christian and Svampa, Silvana and Quintana, Gustavo and Piñero, Gustavo and Teves, Jorge and Seppelt, Ian and Mountain, David and Hunter, John and Balogh, Zsolt and Zaman, Maniruz and Druwé, Patrick and Rutsaert, Robert and Mazairac, Guy and Pascal, Fogang and Yvette, Zognou and Chancellin, Djeuchon and Okwen, Patrick and Djokam-Liapoe, Jules and Jangwa, Ernest and Mbuagbaw, Lawrence and Fointama, Ninying and Pascal, Nguemo and Baillie, Frank and Jiang, Ji-Yao and Gao, Guo-Yi and Bao, Yin-Hui and Morales, Carlos and Sierra, Juan and Naranjo, Santiago and Correa, Camilo and Gómez, Carolina and Herrera, Jorge and Caicedo, Liliana and Rojas, Alexei and Pastas, Henry and Miranda, Hugo and Constaín, Alfredo and Perdomo, Mayla and Muñoz, Diego and Duarte, Álvaro and Vásquez, Edwin and Ortiz, Camilo and Ayala, Bernardo and Delgado, Hernán and Benavides, Gloria and Rosero, Lorena and Mejía-Mantilla, Jorge and Varela, Ana and Calle, Maríaisabel and Castillo, José and García, Alberto and Ciro, Juan and Villa, Clara and Panesso, Roberto and Flórez, Luz and Gallego, Argemiro and Puentes-Manosalva, Fabián and Medina, Leonor and Márquez, Kelly and Romero, Adalgiza Reyes and Hernández, Ricardo and Martínez, Julio and Gualteros, Wilson and Urbina, Zulma and Velandia, Julio and Benítez, Federico and Trochez, Adolfo and Villarreal, Andrés and Pabón, Pamela and López, Héctor and Quintero, Laureano and Rubiano, Andrés and Tamayo, Juan and Piñera, Marjoris and Navarro, Zadis and Rondón, Deborah and Bujan, Bárbara and Palacios, Leonel and Martínez, Daymis and Hernández, Yalisa and Fernández, Yaimara and Casola, Eugenio and Delgado, Rodolfo and Herrera, Carlos and Arbolaéz, Migdacelys and Domínguez, Mario and Iraola, Marcos and Rojas, Omar and Enseñat, Alba and Pastrana, Irene and Rodríguez, Daniel and De La Campa, Sergio Álvarez and ... and Crash 2 Trial Collaborators and CRASH-2 trial collaborators
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9734, pp. 23 - 32
Summary Background Tranexamic acid can reduce bleeding in patients undergoing elective surgery. We assessed the effects of early administration of a short... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | BRAIN-INJURY | EPIDEMIOLOGY | Antifibrinolytic Agents - therapeutic use | Hemorrhage - therapy | Humans | Wounds and Injuries - complications | Hemorrhage - mortality | Male | Tranexamic Acid - therapeutic use | Hemorrhage - drug therapy | Blood Transfusion | Thrombosis - etiology | Hemorrhage - etiology | Adult | Female | Thrombosis - prevention & control | Prevention | Complications and side effects | Tranexamic acid | Dosage and administration | Research | Blood transfusion | Health aspects | Hemorrhage | Risk factors | Colleges & universities | Clinical trials | Blood pressure | Charitable foundations | Trauma | Injuries | Binding sites | Teaching hospitals
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2. Full Text The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
by Olldashi, Fatos and Kerçi, Mihal and Zhurda, Tefik and Ruçi, Klotilda and Banushi, Arben and Traverso, Mario Sardón and Jiménez, Juan and Balbi, Jorge and Dellera, Christian and Svampa, Silvana and Quintana, Gustavo and Piñero, Gustavo and Teves, Jorge and Seppelt, Ian and Mountain, David and Balogh, Zsolt and Zaman, Maniruz and Druwé, Patrick and Rutsaert, Robert and Mazairac, Guy and Pascal, Fogang and Yvette, Zognou and Chancellin, Djeuchon and Okwen, Patrick and Djokam-Liapoe, Jules and Jangwa, Ernest and Mbuagbaw, Lawrence and Fointama, Ninying and Baillie, Frank and Jiang, Ji-Yao and Gao, Guo-Yi and Bao, Yin-Hui and Morales, Carlos and Sierra, Juan and Naranjo, Santiago and Correa, Camilo and Gómez, Carolina and Herrera, Jorge and Caicedo, Liliana and Rojas, Alexei and Pastas, Henry and Miranda, Hugo and Constaín, Alfredo and Perdomo, Mayla and Muñoz, Diego and Duarte, Álvaro and Vásquez, Edwin and Ortiz, Camilo and Ayala, Bernardo and Delgado, Hernán and Benavides, Gloria and Rosero, Lorena and Mejía-Mantilla, Jorge and Varela, Ana and Calle, Maríaisabel and Castillo, José and García, Alberto and Ciro, Juan and Villa, Clara and Panesso, Roberto and Flórez, Luz and Gallego, Argemiro and Puentes-Manosalva, Fabián and Medina, Leonor and Márquez, Kelly and Romero, Adalgiza Reyes and Hernández, Ricardo and Martínez, Julio and Gualteros, Wilson and Urbina, Zulma and Velandia, Julio and Benítez, Federico and Trochez, Adolfo and Villarreal, Andrés and Pabón, Pamela and López, Héctor and Quintero, Laureano and Rubiano, Andrés and Tamayo, Juan and Piñera, Marjoris and Martínez, Daimi and Martínez, Heriberto and Casola, Eugenio and Domínguez, Mario and Herrera, Carlos and Iraola, Marcos and Rojas, Omar and Pastrana, Irene and Rodríguez, Daniel and De La Campa, Sergio Álvarez and Fortún, Thorvald and Larrea, Martha and Aragón, Lensky and Madrazo, Aida and Svoboda, Petr and Izurieta, Mario and Daccach, Alberto and Altamirano, Mónica and Ortega, Antonio and Cárdenas, Bolívar and ... and CRASH-2 Collaborators and CRASH-2 collaborators
Lancet, The, ISSN 0140-6736, 2011, Volume 377, Issue 9771, pp. 1096 - 1101.e2
Summary Background The aim of the CRASH-2 trial was to assess the effects of early administration of tranexamic acid on death, vascular occlusive events, and... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | COAGULOPATHY | Antifibrinolytic Agents - therapeutic use | Hemorrhage - drug therapy | Time Factors | Humans | Wounds and Injuries - complications | Hemorrhage - mortality | Adult | Logistic Models | Tranexamic Acid - therapeutic use | Clinical trials | Data collection | Blood pressure | Statistical analysis | Acids | Charitable foundations
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3. Full Text Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury—outcomes at 6 months
by Baigent, Colin and Bracken, Michael and Chadwick, David and Curley, Kevin and Duley, Lelia and Farrell, Barbara and Haegi, Marcel and Lomas, Gabrielle and Nickson, Graham and Peto, Richard and Pickard, John and Roberts, Ian and Sandercock, Peter and Teasdale, Graham and Wasserberg, Jonathan and Yates, David and Collins, Rory and Haines, Stephen and MacMahon, Stephen and Warlow, Charles and Edwards, Phil and Farrell, Arbara and Lomas, Gabrielle and Ritchie, Nin and Roberts, Ian and Sandercock, Peter and Shakur, Aleema and Teasdale, Graham and Wasserberg, Jonathan and Yates, David and Shakur, Haleema and Roberts, Ian and Edwards, Phil and Ramos, Maria and Barnetson, Lin and Fernandes, Janice and Tooth, Donna and Free, Cari and Narayanan, Leena and Collander, Johan and Abernethy, Julia and Bardswell, Josephine and Ritchie, Nin and Mashru, Reshma and Godward, Catherine and Afolabi, Elizabeth and Ritchie, Adrian and Hosford, Tessa and Pantrini, Shiela and Massey, Sheila and Collingwood, Amber and Edwards, Phil and Arango, Miguel and Balica, Laura and Cottingham, Rowland and El-Sayed, Hesham and Farrell, Barbara and Fernandes, Janice and Gogichaisvili, Tamar and Golden, Nyoman and Hartzenberg, Bennie and Husain, Mazhar and Ulloa, Mario Izurieta and Jerbi, Zouheir and Khamis, Hussein and Komolafe, Edward and Laloë, Véronique and Lomas, Gabrielle and Ludwig, Silke and Mazairac, Guy and De Los Angeles Muñoz Sanchéz, Maria and Nasi, Luis and Olldashi, Fatos and Plunkett, Patrick and Roberts, Ian and Sandercock, Peter and Shakur, Haleema and Soler, Caridad and Stocker, Reto and Svoboda, Petr and Trenkler, Stefan and Venkataramana, N.K and Wasserberg, Jonathan and Yates, David and Yutthakasemsunt, Surakrant and CRASH Trial Collaborators and CRASH trial collaborators
The Lancet, ISSN 0140-6736, 2005, Volume 365, Issue 9475, pp. 1957 - 1959
MRC CRASH is a randomised controlled trial (ISRCTN74459797) of the effect of corticosteroids on death and disability after head injury. We randomly allocated... 
MEDICINE, GENERAL & INTERNAL | Glucocorticoids - administration & dosage | Follow-Up Studies | Craniocerebral Trauma - drug therapy | Humans | Risk Factors | Craniocerebral Trauma - mortality | Treatment Outcome | Infusions, Intravenous | Methylprednisolone - administration & dosage | Head injuries | Corticosteroids | Mortality | United Kingdom | Dosage and administration | Drug therapy | Risk factors | Clinical trials | Adults | Clinical outcomes
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4. Full Text Ditch the bag and be green
by Cottingham, Rowland L
BMJ, ISSN 0959-8138, 2009, Volume 338, Issue 7689, pp. 254 - 254
Bag Ladies and Gentlemen | MEDICINE, GENERAL & INTERNAL
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5. Full Text Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients
by Menon and Harrison and MRC CRASH Trial Collaborators
BMJ, ISSN 0959-8138, 02/2008, Volume 336, Issue 7641, pp. 425 - 429
Objective To develop and validate practical prognostic models for death at 14 days and for death or severe disability six months after traumatic brain... 
High income | Health outcomes | Traumatic brain injury | Low income | Database models | Disabilities | Physical trauma | Computerized axial tomography | Calibration | Research | Modeling | MEDICINE, GENERAL & INTERNAL | HEAD-INJURY | MANAGEMENT | COUNTRIES | ADULTS | VARIABLES | PLACEBO-CONTROLLED TRIAL | MRC CRASH | Multivariate Analysis | Brain Injuries - diagnostic imaging | Prognosis | Glasgow Coma Scale | Humans | Accidents, Traffic - statistics & numerical data | Income | Tomography, X-Ray Computed | Brain Injuries - mortality | Cohort Studies | Outcome Assessment (Health Care) - standards
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6. Full Text Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): Randomised placebo-controlled trial
by Olldashi, Fatos and Muzha, Itan and Filipi, Nikolin and Lede, Roberto and Copertari, Pablo and Traverso, Carolina and Copertari, Alejandro and Vergara, Enrique Alfredo and Montenegro, Carolina and De Huidobro, Roberto Ruiz and Surt, Karina and Cialzeta, José and Lazzeri, Silvio and Piñero, Gustavo and Ciccioli, Fabiana and Videtta, Walter and Barboza, María Fernanda and Svampa, Silvana and Sciuto, Victor and Domeniconi, Gustavo and Bustamante, Marcelo and Waschbusch, Maximiliano and Gullo, María Paula and Drago, Daniel Alberto and Linares, Juan Carlos Arjona and Camputaro, Luis and Tróccoli, Gustavo and Galimberti, Hernán and Tallott, Mandy and Eybner, Christian and Buchinger, Walter and Fitzal, Sylvia and Mazairac, Guy and Oleffe, Véronique and Grollinger, Thierry and Delvaux, Philippe and Carlier, Laurent and Braet, Veronique and Jacques, Jean-Marie and De Knoop, Danielle and Nasi, Luiz and Choi, Humberto Kukhuyn and Schmitt, Mara and Gentil, André and Nacul, Flavio and Barrios, Pedro Bedoya and Xinkang, Chen and Hua, Lin Shao and Tian, Huang Han and Xiaodong, Cai and Gualteros, Wilson and Otero, Alvaro Ardila and Arango, Miguel and Ciro, Juan and Jaramillo, Hector and Garcia, Gloria and Gonzalez, Ignacio and Gomez, Carolina and Arias, Arturo and Fonseca, Marco and Mora, Carlos and Cabrera, Edgar Giovanni Luna and Betancurth, José Luis and Muñoz, Porfirio and Quiñónez, Jesus Alberto and Castillo, Maria Esther Gonzalez and Lopez, Orlando and Yepes, Rafael Perez and Cuellar, Diana Leon and Paez, Gerson and Chaves, Hernán Delgado and Ordoñez, Pablo Emilio and Plata, Ricardo and Pineda, Martha and Pulido, Libardo Enrique and Jaramillo, John Sergio Velez and Rebolledo, Carlos and Palma, Oscar and Soler, Caridad and Pastrana, Irene and Falero, Raul and Perera, Mario Domínguez and García, Agustín Arocha and Oliva, Raydel and Delgado, Hubiel López and Carnero, Aida Madrazo and López, Boris Leyva and Gallardo, Angel Lacerda and Morales, Amarilys Ortega and Lezcano, Humberto and Ferrer, Marcos Iraola and Bess, Irene Zamalea and Canino, Gladys Rivas and Ruiz, Ernesto Miguel Piferrer and Cruz, Orlando Garcia and Svoboda, Petr and Kantorová, Ilona and Ochmann, Jiří and Scheer, Peter and Kozumplík, Ladislav and ... and CRASH Trial Collaborators and CRASH trial collaborators
The Lancet, ISSN 0140-6736, 10/2004, Volume 364, Issue 9442, pp. 1321 - 1328
Background Corticosteroids have been used to treat head injuries for more than 30 years. In 1997, findings of a systematic review suggested that these drugs... 
MEDICINE, GENERAL & INTERNAL | SPINAL-CORD-INJURY | METHYLPREDNISOLONE | BRAIN-INJURY | INTENSIVE-CARE | CARE MANAGEMENT | Glucocorticoids - administration & dosage | Double-Blind Method | Humans | Middle Aged | Risk Factors | Craniocerebral Trauma - mortality | Male | Survival Rate | Tomography, X-Ray Computed | Craniocerebral Trauma - diagnostic imaging | Craniocerebral Trauma - drug therapy | Glasgow Coma Scale | Adolescent | Adult | Female | Infusions, Intravenous | Methylprednisolone - administration & dosage
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7. Full Text CAERvest® - a novel endothermic hypothermic device for core temperature cooling: safety and efficacy testing
by Willmott, Ashley G.B and Bliss, Alex and Simpson, William H and Tocker, Steve M and Cottingham, Rowland and Maxwell, Neil S
International Journal of Occupational Safety and Ergonomics, ISSN 1080-3548, 01/2018, Volume 24, Issue 1, pp. 118 - 128
Introduction. Cooling of the body is used to treat hyperthermic individuals with heatstroke or to depress core temperature below normal for neuroprotection. A... 
cooling | hyperthermia | thermoregulation | targeted temperature management | heat-related illness | ENVIRONMENTS | PHYSIOLOGICAL-RESPONSES | SPORTS-MEDICINE | SPRINT EXERCISE PERFORMANCE | INTERMITTENT | RELIABILITY | ERGONOMICS | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | CARDIAC-ARREST | VEST | EXERTIONAL HEAT-STROKE | RESUSCITATION
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8. Full Text Proposals for preventing community violence are naive
by Cottingham, Rowland
BMJ, ISSN 0959-8138, 03/2001, Volume 322, Issue 7287, pp. 677 - 677
Emergency departments | Political violence | Violence | Letters | Criminal arrests | Physical trauma | Police | MEDICINE, GENERAL & INTERNAL
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9. Full Text Proposals for preventing community violence are naive
by Cottingham, R
BMJ (Clinical research ed.), ISSN 0959-8138, 03/2001, Volume 322, Issue 7287, pp. 677 - 677
Data Collection | Wounds and Injuries - epidemiology | Emergency Service, Hospital - utilization | United Kingdom - epidemiology | Humans | Violence - prevention & control | Letters
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10. Full Text ABC of Spinal Cord Injury: at the accident
: 1
by Rowland L Cottingham
British Medical Journal, ISSN 0267-0623, 01/1986, Volume 292, Issue 6513, p. 138
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11. Full Text ABC of Spinal Cord Injury: at the accident
by Raffle, Andrew and Graham, J C and Baker, Harry
British Medical Journal (Clinical research ed.), ISSN 0267-0623, 01/1986, Volume 292, Issue 6513, pp. 139 - 139
Correspondence
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12. Full Text ABC of Spinal Cord Injury: at the accident
by Cottingham, Rowland L
British Medical Journal (Clinical research ed.), ISSN 0267-0623, 01/1986, Volume 292, Issue 6513, pp. 138 - 139
Correspondence
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13. Full Text ABC of Spinal Cord Injury: at the accident
by Marsden, Andrew K and Chamberlain, D A and Evans, T and Fisher, J and Redmond, T and Robertson, C and Sleet, R A and Steggles, B and Tunstall-Pedoe, H and Ward, M and Zideman, D A
British Medical Journal (Clinical research ed.), ISSN 0267-0623, 01/1986, Volume 292, Issue 6513, pp. 138 - 139
Spinal cord | Head | Vomiting | Spinal injuries | Correspondence | Physical trauma | Intubation | Neck | Ambulances | Accidents | MEDICINE, GENERAL & INTERNAL
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