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Journal Article
The Lancet, ISSN 0140-6736, 2014, Volume 383, Issue 9923, pp. 1129 - 1137
Background Choroideremia is an X-linked recessive disease that leads to blindness due to mutations in the CHM gene, which encodes the Rab escort protein 1... 
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2016, Volume 374, Issue 20, pp. 1996 - 1998
In this study, the subfoveal injection of a gene-therapy vector carrying nonmutated CHM, the gene that, when mutated, causes a form of blindness called... 
MEDICINE, GENERAL & INTERNAL | Cataract - complications | Genetic Therapy | Choroideremia - complications | Humans | Retina | Choroideremia - therapy | Visual Acuity | Cataracts | Diabetic retinopathy | Medical research | Congenital diseases | Blindness | Traffic accidents & safety | Injection | Gene therapy | Patients | Acuity | Index Medicus | Abridged Index Medicus
Journal Article
Vision Research, ISSN 0042-6989, 06/2015, Volume 111, Issue Pt B, pp. 149 - 160
Journal Article
Multiple Sclerosis Journal, ISSN 1352-4585, 2/2019, Volume 25, Issue 2, pp. 246 - 255
Background: Recent basic and clinical evidence suggests amiloride may be neuroprotective in multiple sclerosis (MS) through the blockade of the acid sensing... 
Clinical trial | axonal loss | multiple sclerosis | outcome measurement | MULTIPLE-SCLEROSIS | INJURY | RISK | MECHANISMS | NEUROSCIENCES | NEUROPROTECTION | BRAIN | CLINICAL NEUROLOGY | Neuroprotection | Sodium channels | Multiple sclerosis | Amiloride | Motivation | Optic neuritis | Clinical trials | Retina | Data processing | Visual evoked potentials | Neuritis | Acidity
Journal Article
Ophthalmic Genetics, ISSN 1381-6810, 01/2019, Volume 40, Issue 1, pp. 29 - 33
Background: Nuclear hormone receptor gene, NR2E3, plays a critical role in retinogenesis and determination of the rod photoreceptor phenotype. Mutations in... 
electroretinogram | enhanced S-cone syndrome | gene therapy | retina | NR2E3 | ESCS | ROD | MOUSE | NUCLEAR RECEPTOR NR2E3 | PHOTORECEPTOR DEVELOPMENT | GENES | GENETICS & HEREDITY | OPHTHALMOLOGY | CONCENTRIC AUTOFLUORESCENCE RING | DIFFERENTIATION | MUTATIONS
Journal Article
Neuroreport, ISSN 0959-4965, 08/2001, Volume 12, Issue 11, pp. 2453 - 2456
The success of the M1-selective muscarinic antagonist pirenzepine in preventing myopia development in animal models implicates a role for the M1 receptor.... 
Himbacine | Pirenzepine | Muscarinic receptors | Myopia
Journal Article
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