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1. Full Text Discovery of keratin function and role in genetic diseases: The year that 1991 was
by Coulombe, Pierre A
Molecular Biology of the Cell, ISSN 1059-1524, 09/2016, Volume 27, Issue 18, pp. 2807 - 2810
In 1991, a set of transgenic mouse studies took the fields of cell biology and dermatology by storm in providing the first credible evidence that keratin... 
Intermediate Filaments - genetics | Skin - cytology | Keratins - chemistry | Humans | Mice, Transgenic | Skin Physiological Phenomena | Intermediate Filaments - physiology | Animals | Keratins - metabolism | Keratinocytes - metabolism | Cell Differentiation | Mice | Epidermis - cytology | Keratinocytes - physiology | Retrospectives
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2. Language rights in French Canada
by Coulombe, Pierre A., 1963
1997, Paperback ed., Francophone cultures and literatures, ISBN 9780820425047, Volume 2, viii, 183
Ethnic identity | Civil rights | Language policy | French-Canadians
Book
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3. Full Text Emerging role for the cytoskeleton as an organizer and regulator of translation
by Coulombe, Pierre A and Kim, Seyun
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 01/2010, Volume 11, Issue 1, pp. 75 - 81
The cytoskeleton is an intricate and dynamic fibrous network that has an essential role in the generation and regulation of cell architecture and cellular... 
Microtubules - metabolism | Protein Biosynthesis | Cytoskeleton - physiology | Animals | Cell Proliferation | Humans | Physiological aspects | Cytoskeleton | Genetic aspects | Research | Genetic translation
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4. Intermediate filament cytoskeleton
by Omary, M. Bishr and Coulombe, Pierre A
2004, Methods in cell biology, ISBN 0125641737, Volume 78, xxix, 886 p., [19] p. of plates
"Intermediate filaments, microfilaments and microtubules are the three major cytoskeletal protein families. Several features highlight intermediate filaments... 
physiology | Cytoplasmic filaments | Cytoskeletal proteins | Intermediate Filament Proteins
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5. Full Text Wound epithelialization: accelerating the pace of discovery
by Coulombe, Pierre A
The Journal of investigative dermatology, ISSN 0022-202X, 2003, Volume 121, Issue 2, pp. 219 - 230
Signal Transduction | Skin - metabolism | Humans | Biomarkers - analysis | Epithelium - physiopathology | Wound Healing | Skin - injuries | Wounds, Penetrating - physiopathology | Regeneration | Animals | Keratins - metabolism | Skin - physiopathology | Disease Models, Animal
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6. Full Text The Molecular Revolution in Cutaneous Biology: Keratin Genes and their Associated Disease: Diversity, Opportunities, and Challenges
by Coulombe, Pierre A
Journal of Investigative Dermatology, ISSN 0022-202X, 05/2017, Volume 137, Issue 5, pp. e67 - e71
The abundance of keratin proteins and the filaments they form in surface epithelia has long been appreciated. This said, the remarkable diversity of keratin... 
ORGANIZATION | EPIDERMOLYSIS-BULLOSA SIMPLEX | SKIN TUMOR KERATINOCYTES | SEQUENCE | INTERMEDIATE-FILAMENT PROTEINS | HUMAN TYPE-I | TERMINAL DIFFERENTIATION | CULTURED-CELLS | EXPRESSION | HUMAN EPIDERMAL-CELLS | DERMATOLOGY | Animals | Epithelial Cells - metabolism | Skin Diseases - genetics | Humans | Skin Diseases - pathology | Genome, Human | Keratins - genetics | Skin - pathology
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7. Murailles de craies
by Coulombe, René, 1954 and Drouhard, Jean-Pierre, 1948 and Atelier de production littéraire de la Mauricie
1978, Atelier de production littéraire de la Mauricie, Volume 2, 40
Book
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8. A role for disulfide bonding in keratin intermediate filament organization and dynamics in skin keratinocytes
by Xia Feng and Pierre A Coulombe
The Journal of Cell Biology, ISSN 0021-9525, 04/2015, Volume 209, Issue 1, p. 59
  We recently reported that a trans-dimer, homotypic disulfide bond involving Cys367 in keratin 14 (K14) occurs in an atomic-resolution structure of the... 
Proteins | Cellular biology | Rodents | Polymerization | Skin
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9. Full Text Nathalie Saint-Pierre, scénariste et réalisatrice de Catimini
by Coulombe, Michel
Ciné-Bulles, ISSN 0820-8921, 2013, Volume 31, Issue 1, pp. 8 - 13
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10. Full Text Keratin function in skin epithelia: a broadening palette with surprising shades
by Gu, Li-Hong and Coulombe, Pierre A
Current Opinion in Cell Biology, ISSN 0955-0674, 2006, Volume 19, Issue 1, pp. 13 - 23
Keratins make up the largest subgroup of intermediate filament (IF) proteins and form a dynamic network of 10–12 nm filaments, built from type I/type II... 
Internal Medicine | Hair Follicle - physiology | Intermediate Filaments - genetics | Protein Biosynthesis | Cell Proliferation | Epithelium - metabolism | Skin - metabolism | Humans | Keratins - physiology | Terminology as Topic | Intermediate Filaments - metabolism | Melanins - metabolism | Epithelial Cells - physiology | Animals | Mutation | Keratins - genetics
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11. Le Dictionnaire du cinéma québécois
by Coulombe, Michel and Jean, Marcel, 1963
1991, Nouv. éd. rev. et augm., ISBN 289052423X, xix, 603
Motion pictures | Motion picture producers and directors | Motion picture actors and actresses | French
Book
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12. Full Text The expanding significance of keratin intermediate filaments in normal and diseased epithelia
by Pan, Xiaoou and Hobbs, Ryan P and Coulombe, Pierre A
Current Opinion in Cell Biology, ISSN 0955-0674, 2012, Volume 25, Issue 1, pp. 47 - 56
Intermediate filaments are assembled from a diverse group of evolutionary conserved proteins and are specified in a tissue-dependent, cell type-dependent, and... 
Internal Medicine | EPIDERMOLYSIS-BULLOSA SIMPLEX | DEPENDENT FASHION | TISSUE-REPAIR | SKIN EPITHELIA | SELF-ORGANIZATION | LIVER-DISEASE | MECHANICAL-PROPERTIES | PROTEIN-SYNTHESIS | BASAL-CELL CARCINOMAS | PACHYONYCHIA-CONGENITA | CELL BIOLOGY | Neoplasms - metabolism | Epithelium - pathology | Intermediate Filaments - pathology | Skin Diseases - metabolism | Humans | Stress, Physiological | Homeostasis | Embryonic Development | Skin Diseases - pathology | Intermediate Filaments - chemistry | Intermediate Filaments - physiology | Animals | Cell Nucleus - metabolism | Keratins - metabolism | Epithelium - physiology | Neoplasms - pathology | Apoptosis | Cell Movement | Proteins | Embryonic development | Keratin | Growth
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13. Full Text Intermediate filament scaffolds fulfill mechanical, organizational, and signaling functions in the cytoplasm
by Kim, Seyun and Coulombe, Pierre A
Genes and Development, ISSN 0890-9369, 07/2007, Volume 21, Issue 13, pp. 1581 - 1597
Intermediate filaments (IFs) are cytoskeletal polymers whose protein constituents are encoded by a large family of differentially expressed genes. Owing in... 
Vimentin | Intracellular transport | Keratin | Cytoskeleton | Cell polarity | Adhesion | EPIDERMOLYSIS-BULLOSA SIMPLEX | MARIE-TOOTH-DISEASE | NONHELICAL TAIL DOMAIN | cytoskeleton | MUSCULAR-DYSTROPHY | ALPHA-B-CRYSTALLIN | vimentin | DEVELOPMENTAL BIOLOGY | adhesion | FOCAL ADHESIONS | CELL BIOLOGY | intracellular transport | SIMPLE EPITHELIAL-CELLS | FIBRILLARY ACIDIC PROTEIN | MICE LACKING VIMENTIN | GENETICS & HEREDITY | keratin | cell polarity | TRANSGENIC MICE | Cytoplasmic Streaming - physiology | Cell Proliferation | Humans | Cell Physiological Phenomena | Intermediate Filament Proteins - physiology | Cytoplasm - physiology | Mechanotransduction, Cellular - physiology | Intermediate Filaments - physiology | Regeneration | Animals | Biological Transport | Cell Adhesion - physiology | Models, Biological | Signal Transduction - physiology | Apoptosis - physiology | Genetic regulation | Cytoplasm | Research
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14. Full Text Cytoplasmic intermediate filaments revealed as dynamic and multipurpose scaffolds
by Coulombe, Pierre A and Wong, Pauline
Nature Cell Biology, ISSN 1465-7392, 08/2004, Volume 6, Issue 8, pp. 699 - 706
Intermediate filaments are cytoskeletal polymers encoded by a large family of differentially expressed genes that provide crucial structural support in the... 
EPIDERMOLYSIS-BULLOSA SIMPLEX | KERATIN FILAMENTS | VISCOELASTIC PROPERTIES | A-TYPE LAMINS | HEPATOCYTE INTEGRITY | NECROSIS-FACTOR-ALPHA | CELL-CYCLE | MECHANICAL-PROPERTIES | MOLECULAR PHYLOGENY | TRANSGENIC MICE | CELL BIOLOGY | Cytoplasmic Streaming - physiology | Humans | Stress, Mechanical | Cytoplasm - metabolism | Intermediate Filaments - metabolism | Biopolymers | Intermediate Filaments - chemistry | Molecular Motor Proteins - physiology | Animals | Models, Biological | Cell Division | Cell Death | Intermediate Filament Proteins - metabolism | Physiological aspects | Genetic aspects | Research | Gene expression | Neurons | Intermediate filament proteins
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15. Full Text Defining Keratin Protein Function in Skin Epithelia: Epidermolysis Bullosa Simplex and Its Aftermath
by Coulombe, Pierre A and Lee, Chang-Hun
Journal of Investigative Dermatology, ISSN 0022-202X, 03/2012, Volume 132, Issue 3, pp. 763 - 775
Epidermolysis bullosa simplex (EBS) is a rare genetic condition typified by superficial bullous lesions following incident frictional trauma to the skin. Most... 
MOTTLED PIGMENTATION | GENETIC-BASIS | TRIMETHYLAMINE N-OXIDE | STRESS-RESPONSE | MUSCULAR-DYSTROPHY | INTERMEDIATE-FILAMENT PROTEINS | STRATIFIED SQUAMOUS EPITHELIA | DOWLING-MEARA | EPIDERMAL KERATIN | PRENATAL-DIAGNOSIS | DERMATOLOGY | Intermediate Filaments - genetics | Intermediate Filaments - physiology | Epidermolysis Bullosa Simplex - pathology | Epidermolysis Bullosa Simplex - genetics | Epidermolysis Bullosa Simplex - physiopathology | Keratin-5 - physiology | Humans | Keratin-14 - physiology | Keratin-5 - genetics | Keratin-14 - genetics | Skin - pathology
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16. Full Text A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth
by Coulombe, Pierre A and Kim, Seyun and Wong, Pauline
Nature, ISSN 0028-0836, 05/2006, Volume 441, Issue 7091, pp. 362 - 365
Cell growth, an increase in mass and size, is a highly regulated cellular event. The Akt/mTOR (mammalian target of rapamycin) signalling pathway has a central... 
COMPLEX | SIGNALING PATHWAY | PHOSPHORYLATION | DOWNSTREAM | MULTIDISCIPLINARY SCIENCES | IN-VIVO | SKIN | BINDING | INTERMEDIATE-FILAMENTS | MTOR | PROGRESSION | Protein Kinases - metabolism | Protein Biosynthesis | Epithelial Cells - metabolism | Cells, Cultured | Cytoplasm - metabolism | Keratinocytes - cytology | Keratins - deficiency | Cell Growth Processes | Protein Transport | 14-3-3 Proteins - metabolism | Ectoderm - cytology | Animals | Keratins - metabolism | Keratinocytes - metabolism | Cytoskeleton - metabolism | Protein Binding | Mice | TOR Serine-Threonine Kinases | Epithelial Cells - cytology | Keratins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Proteins | Signal transduction | Cell growth | Injuries
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