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Immunology and Cell Biology, ISSN 0818-9641, 08/2019, Volume 97, Issue 7, pp. 656 - 663
Tuberculosis (TB) kills more individuals each year than any other single pathogen and a more effective vaccine is critical for the global control of the... 
Clinical trials | correlates of protection | vaccine | tuberculosis | MYCOBACTERIUM-TUBERCULOSIS | IMMUNE-RESPONSE | EFFICACY | BCG | SUPERIOR PROTECTION | IMMUNOLOGY | CELL BIOLOGY | DOUBLE-BLIND | CD4(+) | INFECTION | CORRELATE
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e52059
The recently described ESX-5 secretion system of Mycobacterium tuberculosis is one of the most important modulators of host-pathogen interactions due to its... 
Genes | Virulence | Genomes | Gene deletion | Kinases | Macrophages | Machinery | Modulators | Proteins | Clonal deletion | Deletion | Pathogens | Secretion | Cell walls | Conditional mutant | Secretome | Gene expression | Loci | Substrates | Host-pathogen interactions | Membrane proteins | Gene silencing | Tuberculosis | Mutagenesis | Viability | Adenosine triphosphatase
Journal Article
Journal Article
Expert Review of Vaccines, ISSN 1476-0584, 04/2019, Volume 18, Issue 4, pp. 353 - 364
Introduction: The development of more effective tuberculosis (TB) vaccines is essential for the global control of TB. Recently, there have been major advances... 
T lymphocytes | correlates of protection | vaccine | clinical trials | Tuberculosis | TRIALS | INFECTIONS | EFFICACY | SAFETY | BCG | IMMUNOLOGY | IMMUNOGENICITY | T-CELL RESPONSES | MEMORY | DOUBLE-BLIND | CD4(+)
Journal Article
Pneumonia (Nathan Qld.), ISSN 2200-6133, 2016, Volume 8, Issue 1, p. 18
Pediatric tuberculosis (TB) is an underappreciated problem and accounts for 10 % of all TB deaths worldwide. Children are highly susceptible to infection with... 
Journal Article
Tuberculosis, ISSN 1472-9792, 07/2016, Volume 99, p. 25
The characterisation of mycobacterial factors that influence or modulate the host immune response may aid the development of more efficacious TB vaccines. We... 
Antigens | Medical colleges | Tuberculosis vaccines | AIDS vaccines | Tuberculosis | Dendritic cells | Vaccination | Antitubercular agents | Virulence (Microbiology) | T cells | Health aspects
Journal Article
by Kaufmann, Stefan H. E and Dockrell, Hazel M and Drager, Nick and Ho, Mei Mei and McShane, Helen and Neyrolles, Olivier and Ottenhoff, Tom H. M and Patel, Brij and Roordink, Danielle and Spertini, François and Stenger, Steffen and Thole, Jelle and Verreck, Frank A. W and Williams, Ann and Britton, Warwick and Triccas, Jamie and Counoupas, Claudio and Grooten, Johan and Marie-Ange Demoitie, Demoitie and Romano, Marta and Huygen, Kris and Tima, Hermann Giresse and Mascart, Francoise and Andersen, Peter and Aagaard, Claus and Christensen, Dennis and Ruhwald, Morten and Lindenstrom, Thomas and Charneau, Pierre and Guilhot, Christophe and Peixoto, Antonio and Gilleron, Martine and Vergne, Isabelle and Locht, Camille and Brosch, Roland and Inchauspe, Genevieve and Theung Long, Stephane Leung and Weiner, January and Maertzdorf, Jeroen and Nieuwenhuizen, Natalie and Bastian, Max and Kallert, Stephanie and Gordon, Stephen and Caccamo, Nadia and Goletti, Delia and Nisini, Roberto and Shin, Sung Jae and Cho, Sang Nae and Lee, Hyejon and Choi, Ino and Sigal, Alex and Scriba, Thomas and Walzl, Gerhard and Loxton, Andre and Wilkinson, Robert and Wilkinson, Katalin and Cardona, Pere-Joan and Vilaplana, Cris and Martin, Carlos and Marinova, Dessi and Aguilo, Nacho and Aebersold, Ruedi and Caron, Etienne and Pinschewer, Daniel and De Libero, Gennaro and Siegrist, Claire Anne and Collin, Nicolas and Barnier-Quer, Christophe and Sander, Peter and Sutherland, Jayne and Verreck, Frank and Ottenhoff, Tom and Joosten, Simone and Meijgaarden, Krista van and Coppola, Mariateresa and Geluk, Annemieke and Perrie, Yvonne and Baird, Marc and Levin, Michael and Kaforou, Myrsini and Smith, Steven and Fletcher, Helen and Bancroft, Gregory and Clark, Simon and Sharpe, Sally and Satti, Iman and Stylianou, Elena and Tanner, Rachel and Vordermeier, Martin and Hogarth, Philip and Casimiro, Danilo and TBVAC2020 Consortium
Frontiers in Immunology, ISSN 1664-3224, 10/2017, Volume 8, p. 1203
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2010, Volume 142, Issue 1, pp. 14 - 21
The aim of this study was to fabricate and characterize a novel composite scaffold that, combining good mechanical properties with a controlled and sustained... 
Delivery system | Composite scaffold | Fibrin | VEGF | bFGF | BFGF | MYOCARDIUM | VASCULAR GRAFTS | FIBROBLAST | REGENERATION | CONTROLLED-RELEASE | HEPARIN | CHEMISTRY, MULTIDISCIPLINARY | TRIAL | IN-VITRO | POLYURETHANE | PHARMACOLOGY & PHARMACY | BIOMATERIALS | Cell Line | Gene Expression - drug effects | Polyurethanes - chemistry | Humans | Fibroblast Growth Factor 2 - pharmacology | Delayed-Action Preparations - chemistry | Materials Testing | Monocytes - metabolism | Elastic Modulus | Monocytes - immunology | Angiogenesis Inducing Agents - administration & dosage | Fibroblast Growth Factor 2 - administration & dosage | Tissue Scaffolds - chemistry | Monocytes - drug effects | Fibrin - chemistry | Surface Properties | Cell Proliferation - drug effects | Dimethylpolysiloxanes - chemistry | Angiogenesis Inducing Agents - pharmacology | Vascular Endothelial Growth Factor A - administration & dosage | Vascular Endothelial Growth Factor A - pharmacology | Endothelial Cells - drug effects | Messenger RNA | Glycosaminoglycans | Biological products | Mechanical properties | Fibroblast growth factors | Anticoagulants (Medicine) | Vascular endothelial growth factor | Production processes | Enzyme-linked immunosorbent assay | Fibroblast growth factor 2 | Inflammation | Gene expression | LFA-1 antigen | Nitric-oxide synthase | Angiogenesis | Monocytes | scaffolds | Ischemia | Fibrinogen | Heparin | fibrin | Growth factors | Controlled release | Interleukin 8
Journal Article
Tuberculosis, ISSN 1472-9792, 2016, Volume 99, pp. 25 - 30
Summary The characterisation of mycobacterial factors that influence or modulate the host immune response may aid the development of more efficacious TB... 
Infectious Disease | Pulmonary/Respiratory | CD4 T cell immunity | Mycobacterium tuberculosis | Phthiocerol dimycocerosate | Virulence | Vaccination | DENDRITIC CELLS | EFFICACY | BCG | MICROBIOLOGY | IMMUNOLOGY | PROTECTIVE IMMUNITY | TRANSPOSON MUTAGENESIS | RESPIRATORY SYSTEM | CALMETTE-GUERIN VACCINE | MICE | GENERATION | PHOP | Cell Proliferation | Tuberculosis Vaccines - metabolism | Dendritic Cells - immunology | Mycobacterium tuberculosis - immunology | Lipids - immunology | Tuberculosis - microbiology | Vaccines, Attenuated - metabolism | CD4-Positive T-Lymphocytes - immunology | Vaccines, Attenuated - administration & dosage | Female | Tuberculosis Vaccines - immunology | Mycobacterium tuberculosis - metabolism | Tuberculosis - metabolism | Dendritic Cells - metabolism | Disease Models, Animal | CD4-Positive T-Lymphocytes - microbiology | Lymphocyte Activation | Mice, Inbred C57BL | Tuberculosis Vaccines - administration & dosage | CD4-Positive T-Lymphocytes - metabolism | Homeodomain Proteins - genetics | Mice, Knockout | Host-Pathogen Interactions | Tuberculosis - immunology | Vaccines, Attenuated - immunology | Animals | Tuberculosis - prevention & control | BCG Vaccine - immunology | Dendritic Cells - microbiology | Receptors, Antigen, T-Cell - genetics | Mutation | BCG Vaccine - administration & dosage | Mycobacterium tuberculosis - genetics
Journal Article
Infection and Immunity, ISSN 0019-9567, 04/2008, Volume 76, Issue 4, pp. 1719 - 1727
Our previous studies demonstrated that Mycobacterium bovis bacillus Calmette-Guerin (BCG) can directly interact with human NK cells and induce the... 
Journal Article
Canadian Journal of Microbiology, ISSN 0008-4166, 08/2009, Volume 55, Issue 8, p. 975
  The BCG1619c gene of Mycobacterium bovis bacillus Calmette-Guerin (BCG) encodes for a 24 kDa invasin-like protein and is identical to the Rv1566c gene of... 
Cell growth | Microbiology | Lungs | Bacterial proteins | Genes | Bacteria | Mutation | Cells
Journal Article