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2008, Blood-brain barrier : regulatory gatekeeper between brain and body
Web Resource
2008, Blood-brain barrier : understanding the regulatory gatekeeper between brain and body
Web Resource
Medecine/Sciences, ISSN 0767-0974, 08/2016, Volume 32, Issue 8-9, pp. 663 - 664
Journal Article
Fluids and Barriers of the CNS, ISSN 2045-8118, 03/2013, Volume 10, Issue 1, pp. 16 - 16
Since the first attempts in the 1970s to isolate cerebral microvessel endothelial cells (CECs) in order to model the blood-brain barrier (BBB) in vitro, the... 
Brain endothelium | In vitro model | Blood-brain barrier | Immortalized cell line | Toy industry | Endothelium | Proteins | Genotype & phenotype | Cytokines | Cytotoxicity | Permeability | Gene expression | Telomerase | Blood | Chemokines | Molecular weight | Life Sciences | Neurons and Cognition
Journal Article
Journal of neurochemistry, ISSN 0022-3042, 05/2019
Decreased levels of docosahexaenoic acid (DHA), an endogenous neuroprotective compound, in the brain are associated with the development of Alzheimer's disease... 
Journal Article
Journal of Cerebral Blood Flow and Metabolism, ISSN 0271-678X, 2019, pp. 271678X18822801 - 271678X18822801
Exposure of the brain to high levels of glucocorticoids during ischemia-reperfusion induces neuronal cell death. Oxidative stress alters blood-brain barrier... 
P-glycoprotein | Abl kinase | Src kinase | oxidative stress | Blood–brain barrier
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 08/2011, Volume 8, Issue 4, pp. 1332 - 1341
We have investigated the transcriptomic and/or proteomic patterns of 71 solute carrier (SLC) and organic solute (OST) transporters, 34 ATP-binding cassette... 
blood-brain barrier | quantitative LC-MS/MS | transporters | drug-metabolizing enzymes | human | PREGNANE-X RECEPTOR | MEDICINE, RESEARCH & EXPERIMENTAL | BARRIER | P-GLYCOPROTEIN | UDP-GLUCURONOSYLTRANSFERASE | CONSTITUTIVE ANDROSTANE RECEPTOR | PHARMACOLOGY & PHARMACY | GLUTATHIONE-S-TRANSFERASE | RAT-BRAIN | PROTEINS | UP-REGULATION | EXPRESSION | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Glutamate Plasma Membrane Transport Proteins - metabolism | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Microvessels - metabolism | Glucose Transporter Type 1 - metabolism | Glutamate Plasma Membrane Transport Proteins - genetics | Excitatory Amino Acid Transporter 1 - genetics | Neoplasm Proteins - metabolism | Brain - metabolism | Brain - blood supply | Tandem Mass Spectrometry | Glutathione Transferase - genetics | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - metabolism | Chromatography, Liquid | Proteomics - methods | Neoplasm Proteins - genetics | Transcriptome - physiology | Glutathione S-Transferase pi - genetics | Glutathione S-Transferase pi - metabolism | Glutathione Transferase - metabolism | Excitatory Amino Acid Transporter 1 - metabolism | Transcriptome - genetics | Glucose Transporter Type 1 - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | ATP Binding Cassette Transporter, Sub-Family B | In Vitro Techniques | Index Medicus
Journal Article
The Journal of Physiology, ISSN 0022-3751, 04/2008, Volume 586, Issue 7, pp. 1937 - 1949
Homeostasis of the central nervous system (CNS) microenvironment is maintained by the blood–brain barrier (BBB) which regulates the transport of molecules from... 
TUMOR-NECROSIS-FACTOR | TRANSPORT | DEXAMETHASONE | PHYSIOLOGY | MULTIPLE-SCLEROSIS | PERMEABILITY | MICROVASCULAR ENDOTHELIAL-CELLS | CHRONIC INFLAMMATORY PAIN | EXPRESSION | NEUROSCIENCES | HUMAN PROGESTERONE-RECEPTORS | MAMMARY EPITHELIAL-CELLS | Cardiovascular
Journal Article
Journal Article
Fluids and Barriers of the CNS, ISSN 2045-8118, 11/2012, Volume 9, Issue 1, pp. 23 - 23
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2008, Volume 107, Issue 5, pp. 1358 - 1368
The human brain endothelial capillary cell line hCMEC/D3 has been developed recently as a model for the human blood‐brain barrier. In this study a further... 
transendothelial transport | p‐glycoprotein | blood‐brain barrier | ABCB1 | permeability | ABCG2 | p-glycoprotein | Transendothelial transport | Permeability | Blood-brain barrier | blood-brain barrier | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | MICROVESSEL ENDOTHELIUM | TRANSFERRIN RECEPTOR | IN-VITRO MODEL | SITES | MULTIDRUG-RESISTANCE | ASTROCYTIC FACTORS | EXPRESSION | CULTURE MODEL | CANCER RESISTANCE PROTEIN | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Flow Cytometry - methods | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Brain - blood supply | ATP-Binding Cassette Transporters - genetics | Biological Transport | Sucrose - metabolism | ATP-Binding Cassette Transporters - metabolism | Multidrug Resistance-Associated Proteins - genetics | Receptors, Transferrin - genetics | Neoplasm Proteins - genetics | Cell Line | Brain - cytology | Endothelial Cells - metabolism | RNA, Messenger - genetics | Receptors, Transferrin - metabolism | Blood-Brain Barrier - metabolism | Analysis of Variance | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Endothelial Cells - cytology | Midazolam - metabolism | ATP Binding Cassette Transporter, Sub-Family B | Multidrug Resistance-Associated Proteins - metabolism | Proteins | Propranolol hydrochloride | Medical colleges | Brain | Transferrin | Messenger RNA | Analysis | Morphine | Oligosaccharides | Endothelium | Dyes and dyeing | Neurology | Cell culture | Biochemistry | Pharmacology | Index Medicus
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 01/2013, Volume 10, Issue 1, pp. 289 - 296
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 12/2008, Volume 107, Issue 6, pp. 1518 - 1528
We have established the expression patterns of the genes encoding ATP‐binding cassette (ABC) transporters and cytochromes P450 (CYPs) at the adult human... 
ATP‐binding cassette transporters | blood–brain barrier | cytochromes P450 | regulation | human | microvessels | Human | Microvessels | ATP-binding cassette transporters | Regulation | Blood-brain barrier | Cytochromes P450 | blood-brain barrier | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG-RESISTANCE | PREGNANE-X-RECEPTOR | NEUROSCIENCES | MICROVESSEL ENDOTHELIUM | P-GLYCOPROTEIN | ARYL-HYDROCARBON RECEPTOR | CONSTITUTIVE ANDROSTANE RECEPTOR | ENDOTHELIAL-CELLS | CENTRAL-NERVOUS-SYSTEM | UP-REGULATION | CANCER RESISTANCE PROTEIN | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Humans | Brain Neoplasms - pathology | Cerebral Cortex - pathology | Microvessels - metabolism | Cytochrome P-450 Enzyme System - metabolism | Proteoglycans - metabolism | Antigens - metabolism | Glial Fibrillary Acidic Protein - metabolism | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Cerebral Cortex - metabolism | Blood-Brain Barrier - metabolism | ATP-Binding Cassette Transporters - genetics | Gene Expression - physiology | ATP-Binding Cassette Transporters - metabolism | Cytochrome P-450 Enzyme System - genetics | Gene Expression Regulation, Neoplastic - physiology | Synaptophysin - metabolism | Gliomas | Neurons | Brain tumors | Cytochrome P-450 | Hydrocarbons | DNA binding proteins | Television broadcasting industry | Gene expression | Neurology | Brain | Biochemistry | Adenosine triphosphatase | Index Medicus
Journal Article