Lancet Infectious Diseases, The, ISSN 1473-3099, 2017, Volume 17, Issue 5, pp. 510 - 519
Summary Background Listeriosis is a severe foodborne infection and a notifiable disease in France. We did a nationwide prospective study to characterise its...
Infectious Disease | MORTALITY | MENINGITIS | INFECTIOUS DISEASES | MONOCYTOGENES | RISK-FACTORS | MANAGEMENT | GUIDELINES | SURVEILLANCE | PREGNANCY | Foodborne Diseases - microbiology | Infant, Newborn, Diseases - epidemiology | Prognosis | Prospective Studies | Humans | Listeriosis - diagnosis | Bacteremia - mortality | Male | Infant, Newborn, Diseases - microbiology | Listeriosis - epidemiology | Mandatory Reporting | Listeria monocytogenes - classification | Adult | Female | Pregnancy Complications, Infectious - microbiology | Infant, Newborn | Meningoencephalitis - epidemiology | France - epidemiology | Meningoencephalitis - mortality | Pregnancy Complications, Infectious - epidemiology | Risk Factors | Listeria monocytogenes - isolation & purification | Hospitalization | Infectious Disease Transmission, Vertical | Pregnancy | Meningoencephalitis - microbiology | Bacteremia - epidemiology | Listeriosis - microbiology | Aged | Population Surveillance | Listeriosis | Neonates | Food-borne diseases | Disease | Brain stem | Clinical trials | Infections | Genomes | Gestation | Epidemiology | Risk factors | Windows (intervals) | Listeria | Meningitis | Public health | Food | Dexamethasone | Bacterial infections | Mortality | Fetuses | Regression analysis | Clustering | Patients | Bacteremia | Meningoencephalitis | Studies | Surveillance | Medical prognosis | Health risk assessment | Cancer | Life Sciences
Infectious Disease | MORTALITY | MENINGITIS | INFECTIOUS DISEASES | MONOCYTOGENES | RISK-FACTORS | MANAGEMENT | GUIDELINES | SURVEILLANCE | PREGNANCY | Foodborne Diseases - microbiology | Infant, Newborn, Diseases - epidemiology | Prognosis | Prospective Studies | Humans | Listeriosis - diagnosis | Bacteremia - mortality | Male | Infant, Newborn, Diseases - microbiology | Listeriosis - epidemiology | Mandatory Reporting | Listeria monocytogenes - classification | Adult | Female | Pregnancy Complications, Infectious - microbiology | Infant, Newborn | Meningoencephalitis - epidemiology | France - epidemiology | Meningoencephalitis - mortality | Pregnancy Complications, Infectious - epidemiology | Risk Factors | Listeria monocytogenes - isolation & purification | Hospitalization | Infectious Disease Transmission, Vertical | Pregnancy | Meningoencephalitis - microbiology | Bacteremia - epidemiology | Listeriosis - microbiology | Aged | Population Surveillance | Listeriosis | Neonates | Food-borne diseases | Disease | Brain stem | Clinical trials | Infections | Genomes | Gestation | Epidemiology | Risk factors | Windows (intervals) | Listeria | Meningitis | Public health | Food | Dexamethasone | Bacterial infections | Mortality | Fetuses | Regression analysis | Clustering | Patients | Bacteremia | Meningoencephalitis | Studies | Surveillance | Medical prognosis | Health risk assessment | Cancer | Life Sciences
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2016, Volume 26, Issue 11, pp. 1242 - 1254
Introduction of clonal reproduction through seeds (apomixis) in crops has the potential to revolutionize agricul- ture by allowing self-propagation of any...
无融合生殖 | Arabidopsis | 无性繁殖作物 | 有丝分裂 | 减数分裂 | 水稻 | 转化 | 种子繁殖 | MiMe | apomixis | meiosis | mitosis | rice | ARABIDOPSIS-THALIANA | MONOPOLAR ORIENTATION | STRAND BREAK FORMATION | CELL BIOLOGY | DATABASE | PLANTS | MAIZE | REVERSE GENETICS | REPRODUCTION | MEIOTIC RECOMBINATION | Meiosis - physiology | Oryza - metabolism | Cell Cycle Proteins - metabolism | Cell Cycle Proteins - classification | Genotype | Chromosomes, Plant - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Plant Proteins - genetics | Diploidy | Oryza - growth & development | Phenotype | Plant Proteins - classification | Mitosis - physiology | Oryza - genetics | Cell Cycle Proteins - genetics | Plant Proteins - metabolism | Mutation | Chromosomes, Plant - genetics | Life Sciences | Original
无融合生殖 | Arabidopsis | 无性繁殖作物 | 有丝分裂 | 减数分裂 | 水稻 | 转化 | 种子繁殖 | MiMe | apomixis | meiosis | mitosis | rice | ARABIDOPSIS-THALIANA | MONOPOLAR ORIENTATION | STRAND BREAK FORMATION | CELL BIOLOGY | DATABASE | PLANTS | MAIZE | REVERSE GENETICS | REPRODUCTION | MEIOTIC RECOMBINATION | Meiosis - physiology | Oryza - metabolism | Cell Cycle Proteins - metabolism | Cell Cycle Proteins - classification | Genotype | Chromosomes, Plant - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Plant Proteins - genetics | Diploidy | Oryza - growth & development | Phenotype | Plant Proteins - classification | Mitosis - physiology | Oryza - genetics | Cell Cycle Proteins - genetics | Plant Proteins - metabolism | Mutation | Chromosomes, Plant - genetics | Life Sciences | Original
Journal Article
PLoS Pathogens, ISSN 1553-7366, 10/2013, Volume 9, Issue 10, p. e1003731
Background: In order to promote infection, the blood-borne parasite Trypanosoma brucei releases factors that upregulate arginase expression and activity in...
GAMMA | MASS-SPECTROMETRY DATA | EXPERIMENTAL AFRICAN TRYPANOSOMIASIS | MACROPHAGES | MICROBIOLOGY | IN-VITRO CULTURE | NITRIC-OXIDE PRODUCTION | VIROLOGY | SURFACE GLYCOPROTEIN | RESISTANCE | INFECTION | PARASITOLOGY | INDUCIBLE EXPRESSION SYSTEM | Cell Adhesion Molecules - genetics | Lectins, C-Type - immunology | Cell Adhesion Molecules - immunology | Lectins, C-Type - genetics | Protozoan Proteins - genetics | Enzyme Activation - immunology | Arginase - immunology | Kinesin - genetics | Trypanosomiasis, African - pathology | Trypanosomiasis, African - genetics | Nitric Oxide - immunology | Arginase - genetics | Trypanosoma brucei brucei - genetics | Receptors, Cell Surface - immunology | Mice, Knockout | Kinesin - immunology | Trypanosomiasis, African - immunology | Animals | Interleukin-10 - genetics | Nitric Oxide - genetics | Mice | Enzyme Activation - genetics | Interleukin-10 - immunology | Protozoan Proteins - immunology | Receptors, Cell Surface - genetics | Trypanosoma brucei brucei - immunology | Physiological aspects | Host-parasite relationships | Trypanosoma | Research | Health aspects | Kinesin | Immunology | Rodents | Liver | Infections | Parasites | Gene expression | Polyamines
GAMMA | MASS-SPECTROMETRY DATA | EXPERIMENTAL AFRICAN TRYPANOSOMIASIS | MACROPHAGES | MICROBIOLOGY | IN-VITRO CULTURE | NITRIC-OXIDE PRODUCTION | VIROLOGY | SURFACE GLYCOPROTEIN | RESISTANCE | INFECTION | PARASITOLOGY | INDUCIBLE EXPRESSION SYSTEM | Cell Adhesion Molecules - genetics | Lectins, C-Type - immunology | Cell Adhesion Molecules - immunology | Lectins, C-Type - genetics | Protozoan Proteins - genetics | Enzyme Activation - immunology | Arginase - immunology | Kinesin - genetics | Trypanosomiasis, African - pathology | Trypanosomiasis, African - genetics | Nitric Oxide - immunology | Arginase - genetics | Trypanosoma brucei brucei - genetics | Receptors, Cell Surface - immunology | Mice, Knockout | Kinesin - immunology | Trypanosomiasis, African - immunology | Animals | Interleukin-10 - genetics | Nitric Oxide - genetics | Mice | Enzyme Activation - genetics | Interleukin-10 - immunology | Protozoan Proteins - immunology | Receptors, Cell Surface - genetics | Trypanosoma brucei brucei - immunology | Physiological aspects | Host-parasite relationships | Trypanosoma | Research | Health aspects | Kinesin | Immunology | Rodents | Liver | Infections | Parasites | Gene expression | Polyamines
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 2013, Volume 7, Issue 12, p. e2587
Background The bloodstream forms of Trypanosoma brucei, the causative agent of sleeping sickness, rely solely on glycolysis for ATP production. It is generally...
FATTY-ACID SYNTHESIS | SUCCINATE COA-TRANSFERASE | PROCYCLIC TRYPANOSOMES | LIPID BIOSYNTHESIS | GLUCOSE-METABOLISM | CULTURE FORMS | ENERGY-METABOLISM | CARBOHYDRATE-METABOLISM | PROLINE METABOLISM | DEHYDROGENASE | PARASITOLOGY | TROPICAL MEDICINE | Reverse Genetics | Magnetic Resonance Spectroscopy | Trypanosoma brucei brucei - metabolism | Acetates - metabolism | Mitochondria - metabolism | Threonine - metabolism | Trypanosoma brucei brucei - chemistry | Trypanosoma brucei brucei - physiology | Metabolic Networks and Pathways - genetics | Animals | Succinic Acid - metabolism | Survival Analysis | Glucose - metabolism | Female | Mice, Inbred BALB C | Blood - parasitology | Glucose metabolism | Distribution | Physiological aspects | HIV patients | Research | Trypanosoma brucei | Health aspects | Studies | Enzymes | Genotype & phenotype | Dehydrogenases | Amino acids | Biosynthesis | Metabolism | Fatty acids | Carbon | Apoptosis
FATTY-ACID SYNTHESIS | SUCCINATE COA-TRANSFERASE | PROCYCLIC TRYPANOSOMES | LIPID BIOSYNTHESIS | GLUCOSE-METABOLISM | CULTURE FORMS | ENERGY-METABOLISM | CARBOHYDRATE-METABOLISM | PROLINE METABOLISM | DEHYDROGENASE | PARASITOLOGY | TROPICAL MEDICINE | Reverse Genetics | Magnetic Resonance Spectroscopy | Trypanosoma brucei brucei - metabolism | Acetates - metabolism | Mitochondria - metabolism | Threonine - metabolism | Trypanosoma brucei brucei - chemistry | Trypanosoma brucei brucei - physiology | Metabolic Networks and Pathways - genetics | Animals | Succinic Acid - metabolism | Survival Analysis | Glucose - metabolism | Female | Mice, Inbred BALB C | Blood - parasitology | Glucose metabolism | Distribution | Physiological aspects | HIV patients | Research | Trypanosoma brucei | Health aspects | Studies | Enzymes | Genotype & phenotype | Dehydrogenases | Amino acids | Biosynthesis | Metabolism | Fatty acids | Carbon | Apoptosis
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 11/2016, Volume 10, Issue 11, pp. e0005125 - e0005125
Trypanosoma brucei gambiense is the main causative agent of Human African Trypanosomiasis (HAT), also known as sleeping sickness. Because of limited...
POSACONAZOLE | CRUZI | STEROL 14-ALPHA-DEMETHYLASE | EFLORNITHINE COMBINATION THERAPY | BLOOD-STREAM | GAMBIENSE | SCH 56592 | NIFURTIMOX | BRAIN | PARASITOLOGY | TROPICAL MEDICINE | INDUCIBLE EXPRESSION | Trypanosomiasis, African - drug therapy | Doxycycline - therapeutic use | Sterol 14-Demethylase - genetics | Humans | Cytokinesis | Eflornithine - therapeutic use | Trypanosoma brucei brucei - enzymology | Trypanosoma brucei brucei - drug effects | Triazoles - pharmacology | Anti-Bacterial Agents - therapeutic use | Trypanosomiasis, African - parasitology | Phenotype | Animals | 14-alpha Demethylase Inhibitors - pharmacology | RNA Interference | Trypanosoma brucei brucei - pathogenicity | Ergosterol - pharmacology | Trypanocidal Agents - therapeutic use | Mice | Sterol 14-Demethylase - metabolism | Nifurtimox - therapeutic use | Trypanosoma brucei brucei - growth & development | Disease Models, Animal | Triazoles - therapeutic use | Triazoles | Cytochrome P-450 | Physiological aspects | Virulence (Microbiology) | Research | Trypanosoma brucei | Health aspects | Enzymes | Hospitals | Sterols | Funding | Parasitic diseases | Colleges & universities | Parasites | Tropical diseases | Index Medicus
POSACONAZOLE | CRUZI | STEROL 14-ALPHA-DEMETHYLASE | EFLORNITHINE COMBINATION THERAPY | BLOOD-STREAM | GAMBIENSE | SCH 56592 | NIFURTIMOX | BRAIN | PARASITOLOGY | TROPICAL MEDICINE | INDUCIBLE EXPRESSION | Trypanosomiasis, African - drug therapy | Doxycycline - therapeutic use | Sterol 14-Demethylase - genetics | Humans | Cytokinesis | Eflornithine - therapeutic use | Trypanosoma brucei brucei - enzymology | Trypanosoma brucei brucei - drug effects | Triazoles - pharmacology | Anti-Bacterial Agents - therapeutic use | Trypanosomiasis, African - parasitology | Phenotype | Animals | 14-alpha Demethylase Inhibitors - pharmacology | RNA Interference | Trypanosoma brucei brucei - pathogenicity | Ergosterol - pharmacology | Trypanocidal Agents - therapeutic use | Mice | Sterol 14-Demethylase - metabolism | Nifurtimox - therapeutic use | Trypanosoma brucei brucei - growth & development | Disease Models, Animal | Triazoles - therapeutic use | Triazoles | Cytochrome P-450 | Physiological aspects | Virulence (Microbiology) | Research | Trypanosoma brucei | Health aspects | Enzymes | Hospitals | Sterols | Funding | Parasitic diseases | Colleges & universities | Parasites | Tropical diseases | Index Medicus
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 09/2017, Volume 199, Issue 5, pp. 1762 - 1771
Arginase activity induction in macrophages is an escape mechanism developed by parasites to cope with the host's immune defense and benefit from increased...
CELLS | C-TYPE LECTINS | IMMUNE-RESPONSES | INVITRO GROWTH | MACROPHAGES | MOUSE | BRUCEI | IMMUNOLOGY | IDENTIFICATION | TRYPANOTHIONE | SURFACE-ANTIGENS | Vector-borne diseases | Immune response | Vaccination | Arginase | Chains | Homology | Infections | Mannose | Parasites | Metabolism | Macrophages | Receptors | Monoclonal antibodies | Inhibition | Bioinformatics | Trypanosomiasis | Kinesin | Trypanosome | Immune system | Neutralization
CELLS | C-TYPE LECTINS | IMMUNE-RESPONSES | INVITRO GROWTH | MACROPHAGES | MOUSE | BRUCEI | IMMUNOLOGY | IDENTIFICATION | TRYPANOTHIONE | SURFACE-ANTIGENS | Vector-borne diseases | Immune response | Vaccination | Arginase | Chains | Homology | Infections | Mannose | Parasites | Metabolism | Macrophages | Receptors | Monoclonal antibodies | Inhibition | Bioinformatics | Trypanosomiasis | Kinesin | Trypanosome | Immune system | Neutralization
Journal Article