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science & technology (8) 8
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adolescent; age factors; alleles; body mass index; breast neoplasms/genetics; cardiovascular diseases/genetics; child; diabetes mellitus, type 2/genetics; europe/ethnology; female; genetic loci/genetics; genome-wide association study; genomic imprinting/genetics; humans; hypothalamo-hypophyseal system/physiology; intercellular signaling peptides and proteins/genetics; male; membrane proteins/genetics; menarche/genetics; obesity/genetics; ovary/physiology; parents; polymorphism, single nucleotide/genetics; potassium channels, tandem pore domain/genetics; proteins/genetics; quantitative trait loci/genetics; receptors, gaba-b/metabolism; receptors, retinoic acid/metabolism; ribonucleoproteins/genetics (1) 1
adolescent; aging/physiology; body height/genetics; body size/genetics; child; dna copy number variations/genetics; female; genetic loci/genetics; genetic predisposition to disease; genome-wide association study; humans; inheritance patterns/genetics; menarche/genetics; obesity/genetics; polymorphism, single nucleotide/genetics; quantitative trait loci/genetics; reproducibility of results; time factors ; colaus study (1) 1
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apoptosis regulatory proteins (1) 1
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aryl hydrocarbon hydroxylases - genetics (1) 1
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australian ovarian cancer study (1) 1
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1. Full Text Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
by Perry, John and Day, Felix and Elks, Cathy and Sulem, Patrick and Thompson, Deborah and Ferreira, Teresa and He, Chunyan and Chasman, Daniel and Esko, Tõnu and Thorleifsson, Gudmar and Albrecht, Eva and Ang, Wei and Corre, Tanguy and Cousminer, Diana and Feenstra, Bjarke and Franceschini, Nora and Ganna, Anea and Johnson, Anew and Kjellqvist, Sanela and Lunetta, Kathryn and Mcmahon, George and Nolte, Ilja and Paternoster, Lavinia and Porcu, Eleonora and Smith, Davey and Stolk, Lisette and Teumer, Alexander and Tsernikova, Natalia and Tikkanen, Emmi and Ulivi, Shelia and Wagner, Erin K and Amin, Najaf and Bierut, Laura and Byrne, Enda and Hottenga, Jouke Jan and Koller, Daniel and Mangino, Massimo and Pers, Tune and Yerges-Armstrong, Laura and Zhao, Jing Hua and Anulis, Irene and Anton-Culver, Hoda and Atsma, Femke and Bandinelli, Stefania and Beckmann, Matthias and Benítez, Javier and Blomqvist, Carl and Bojesen, Stig and Bolla, Manjeet and Bonnani, Bernardo and Brauch, Hiltrud and Brenner, Hermann and Buring, Julie and Chang-Claude, Jenny and Chanock, Stephen and Chen, Jinhui and Chenevix-Trench, Georgia and Collée, Margriet and Couch, Fergus and Couper, David and Coviello, Anea and Cox, Angela and Czene, Kamila and Adamo, Pio and Vivo, Immaculata and Demerath, Ellen and Dennis, Joe and Devilee, Peter and Dieffenbach, Aida Karina and Dunning, Alison and Eiriksdottir, Gudny and Hagen, Knut and Fasching, Peter and Ferrucci, Luigi and Flesch-Janys, Dieter and Flyger, Henrik and Foroud, Tatiana and Franke, Lude and Garcia, Melissa and García-Closas, Montserrat and Geller, Frank and Geus, Eco and Giles, Graham and Gudbjartsson, Daniel and Gudnason, Vilmundur and Guénel, Pascal and Guo, Suiqun and Hall, Per and Hamann, Ute and Haring, Robin and Hartman, Catharina and Heath, Anew and Hofman, Albert and Hooning, Maartje and Hopper, John and Hu, Frank and Hunter, David and Karasik, David and Kiel, Douglas P and Knight, Julia and ... and kConFabt LifeLines Cohort Study and InterAct Consortium and Australian Ovarian Canc Study and Early Growth Genetics EGG Consorti and GENICA Network and Australian Ovarian Cancer Study and kConFab and LifeLines Cohort Study and Early Growth Genetics (EGG) Consortium and The GENICA Network and The InterAct Consortium and The LifeLines Cohort Study
Nature (London), ISSN 0028-0836, 10/2014, Volume 514, Issue 7520, pp. 92 - 97
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Age Factors | Diabetes Mellitus, Type 2 - genetics | Humans | Genetic Loci - genetics | Parents | Male | Cardiovascular Diseases - genetics | Obesity - genetics | Europe - ethnology | Female | Ribonucleoproteins - genetics | Hypothalamo-Hypophyseal System - physiology | Child | Body Mass Index | Genome-Wide Association Study | Calcium-Binding Proteins | Membrane Proteins - genetics | Menarche - genetics | Intercellular Signaling Peptides and Proteins - genetics | Potassium Channels, Tandem Pore Domain - genetics | Ovary - physiology | Receptors, Retinoic Acid - metabolism | Genomic Imprinting - genetics | Proteins - genetics | Breast Neoplasms - genetics | Adolescent | Alleles | Polymorphism, Single Nucleotide - genetics | Quantitative Trait Loci - genetics | Receptors, GABA-B - metabolism | Allelomorphism | Menarche | Physiological aspects | Genome-wide association studies | Genetic aspects | Vitamin A | Puberty | Menstruation | Acids | Genomes | Mutation | Chromosomes | Girls | Age | Index Medicus | Medicin och hälsovetenskap
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2. Full Text Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
by Elks, Cathy and Perry, John and Sulem, Patrick and Chasman, Daniel and Franceschini, Nora and He, Chunyan and Lunetta, Kathryn and Visser, Jenny and Byrne, Enda and Cousminer, Diana and Gudbjartsson, Daniel and Esko, Tõnu and Feenstra, Bjarke and Hottenga, Jouke Jan and Koller, Daniel and Kutalik, Zoltán and Lin, Peng and Mangino, Massimo and Marongiu, Mara and McArdle, Patrick and Smith, Albert Vernon and Stolk, Lisette and Wingerden, Sophie and Zhao, Jing Hua and Albrecht, Eva and Corre, Tanguy and Ingelsson, Erik and Hayward, Caroline and Magnusson, Patrik and Ulivi, Shelia and Warrington, Nicole and Zgaga, Lina and Alavere, Helene and Amin, Najaf and Aspelund, Thor and Bandinelli, Stefania and Barroso, Inês and Berenson, Gerald and Bergmann, Sven and Blackburn, Hannah and Boerwinkle, Eric and Buring, Julie and Busonero, F and Campbell, Harry and Chanock, Stephen and Chen, Wei and Cornelis, Marilyn and Couper, David and Coviello, Anea and Adamo, Pio and Faire, Ulf and Geus, Eco and Deloukas, Panagiotis and Döring, Angela and Easton, Douglas and Eiriksdottir, Gudny and Emilsson, Valur and Eriksson, Johan and Ferrucci, Luigi and Folsom, Aaron and Foroud, Tatiana and Garcia, Melissa and Gasparini, Paolo and Geller, Frank and Gieger, Christian and Gudnason, Vilmundur and Hall, Alistair and Hankinson, Susan and Ferreli, Liana and Heath, Anew and Hernandez, Dena and Hofman, Albert and Hu, Frank and Illig, Thomas and Järvelin, M.R and Johnson, Anew and Karasik, David and Khaw, Kay-Tee and Kiel, Douglas and Kilpelänen, Tuomas and Kolcic, Ivana and Kraft, Peter and Launer, Lenore and Laven, Joop and Li, Shengxu and Liu, Jianjun and Levy, Daniel and Martin, Nicholas and Melbye, Mads and Mooser, Vincent and Murray, Jeffrey and Nalls, Michael and Navarro, Pau and Nelis, Mari and Ness, Anew and Northstone, Kate and Oostra, Ben and Peacock, Munro and Palmer, Cameron and Palotie, Aarno and ... and GIANT Consortium and The GIANT Consortium
Nature genetics, ISSN 1061-4036, 12/2010, Volume 42, Issue 12, pp. 1077 - 1085
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Menarche - genetics | Humans | Genetic Loci - genetics | DNA Copy Number Variations - genetics | Obesity - genetics | Body Height - genetics | Aging - physiology | Time Factors | Adolescent | Inheritance Patterns - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Size - genetics | Child | Quantitative Trait Loci - genetics | Quantitative trait loci | Menstruation | Synthesis | Physiological aspects | Genetic aspects | Research | Fatty acids | Puberty | Genetics | Chromosomes | Meta-analysis | Index Medicus | Medicin och hälsovetenskap
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3. Full Text Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men
by Eriksson, A.L and Perry, J.R.B and Coviello, Anea and Delgado, G and Ferrucci, Luigi and Hoffman, A.R and Huhtaniemi, I and Ikram, Arfan and Karlsson, Magnus and Kleber, Marcus and Laughlin, G.A and Liu, YongMei and Lorentzon, Mattias and Lunetta, Kathryn and Mellström, Dan and Murabito, Joanne and Murray, A and Nethander, Maria and Nielson, Carrie and Prokopenko, Inga and Pye, Stephen and Raffel, L.J and Rivadeneira, F and Srikanth, Priya and Stolk, Lisette and Teumer, Alexander and Travison, T.G and Uitterlinden, Ané and Vaidya, Dhananjay and Vanderschueren, Dirk and Zmuda, Joseph and März, Winfried and Orwoll, Eric and Ouyang, Pamela and Vandenput, Liesbeth and Wu, F.C.W and de Jong, F.H and Bhasin, Shalender and Kiel, Douglas P and Ohlsson, Claes and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
The journal of clinical endocrinology and metabolism, ISSN 0021-972X, 03/2018, Volume 103, Issue 3, pp. 991 - 1004
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Estradiol - blood | Estrone - genetics | Genome-Wide Association Study | Bone Density - physiology | Estradiol - genetics | Humans | Gene Expression Regulation - physiology | Estrone - blood | Genotype | Male | Bone Density - genetics | Gonadal Steroid Hormones - blood | Chromosomes, Human, X | Aromatase - genetics | Insulin Resistance - physiology | Insulin Resistance - genetics | Mendelian Randomization Analysis | Female | Polymorphism, Single Nucleotide | Testosterone - blood | Lumbar Vertebrae - physiology | Cohort Studies | Estradiol - physiology | Spine (lumbar) | Estrone | Heritability | Bone mineral density | Genomes | Bone density | Estradiol | Steroid 11β-hydroxylase | Epidemiology | Insulin | Index Medicus | Abridged Index Medicus | Single Nucleotide | Medicinsk genetik | Medical Genetics | genetics | Aromatase | Chromosomes | Human | Bone Density | Gene Expression Regulation | Insulin Resistance | physiology | blood | Gonadal Steroid Hormones | Testosterone | Lumbar Vertebrae | Polymorphism
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4. Full Text Rare coding variants and X-linked loci associated with age at menarche
by Lunetta, Kathryn and Day, Felix and Sulem, Patrick and Ruth, Katherine S and Tung, Joyce Y and Hinds, David A and Esko, Tõnu and Elks, Cathy and Altmaier, Elizabeth and He, Chunyan and Huffman, Jennifer and Mihailov, Evelin and Porcu, Eleonora and Robino, Antonietta and Rose, Lynda and Schick, Ursula and Stolk, Lisette and Teumer, Alexander and Thompson, Deborah and Traglia, Michela and Wang, Carol A and Yerges-Armstrong, Laura and Antoniou, Antonis and Barbieri, Caterina and Coviello, Anea and Cucca, Francesco and Demerath, Ellen and Dunning, Alison and Gandin, Ilaria and Grove, Megan L and Gudbjartsson, Daniel and Hocking, Lynne and Hofman, Albert and Huang, Jian and Jackson, Rebecca and Karasik, David and Kriebel, Jennifer and Lange, Ethan and Lange, Leslie and Langenberg, Claudia and Li, Xin and Luan, J and Mägi, Reedik and Morrison, Alanna and Padmanabhan, Sandosh and Pirie, Ailith and Polasek, Ozren and Porteous, David J and Reiner, Alexander and Rivadeneira Ramirez, Fernando and Rudan, Igor and Sala, Cinzia and Schlessinger, David and Scott, Robert and Stöckl, Doris and Visser, Jenny and Völker, Uwe and Vozzi, Diego and Wilson, James and Zygmunt, Marek and Boerwinkle, Eric and Buring, Julie and Crisponi, Laura and Easton, Douglas and Hayward, Caroline and Hu, Frank and Liu, Simin and Metspalu, Anes and Pennell, Craig and Ridker, Paul and Strauch, Konstantin and Streeten, Elizabeth and Toniolo, Daniela and Uitterlinden, Ané and Ulivi, Shelia and Völzke, Henry and Wareham, Nick and Wellons, Melissa and Franceschini, Nora and Chasman, Daniel and Thorsteinsdottir, Unnur and Murray, Anna and Zwart, John-Anker and Murabito, Joanne and Ong, Ken and Perry, John and Forouhi, Nita G and Kerrison, Nicola D and Sharp, Stephen J and Sims, Matthew and Barroso, Inês and Deloukas, Panagiotis and McCarthy, Mark and Arriola, Larraitz and Balkau, Beverley and Barricarte, Aurelio and Boeing, Heiner and Franks, P.W and Gonzalez, Carlos and Grioni, Sara and ... and Generation Scotland and EPIC-InterAct Consortium
Nature communications, ISSN 2041-1723, 08/2015, Volume 6, Issue 1, pp. 7756 - 7756
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | RNA-Binding Proteins - genetics | Fatty Acids | Age Factors | Humans | Middle Aged | Amides | Immunoglobulins - genetics | Mutation, Missense | Autoantigens - genetics | Genetic Variation | Young Adult | RNA Interference | Adult | Female | Energy Metabolism - genetics | Receptors, Neurokinin-3 - genetics | European Continental Ancestry Group - genetics | Chromosomes, Human, X - genetics | Genes, X-Linked - genetics | Membrane Proteins - genetics | Menarche - genetics | Gene Frequency | Genotype | Penetrance | Signal Transduction - genetics | Codon, Nonsense | Hypogonadism - genetics | Laminin - genetics | Proteins - genetics | Phenotype | Adolescent | Aged | AMP-Activated Protein Kinases - genetics | Index Medicus | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
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5. Full Text Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
by Hinney, Anke and Kesselmeier, M and Jall, S and Volckmar, A.-L and Föcker, M and Antel, J and Heid, Iris and Winkler, Thomas W and Grant, S.F.A and Guo, Yongli and Bergen, Anew and Grant, Struan and Berrettini, Wade and Hakonarson, Hakon and Herpertz-Dahlmann, B and De Zwaan, M and Herzog, W and Ehrlich, Stefan and Zipfel, S and Egberts, Karin and Adan, R and Brandys, M and Elburg, Annemarie and Boraska Perica, V and Müller, T.D and Tschöp, M.H and Zeggini, Eleftheria and Bulik, C.M and Collier, David and Scherag, A and Hebebrand, J and Tschop, Matthias and Floyd, Jamie and Thornton, Laura and Huckins, L.M and Southam, Lorraine and Rayner, Nigel William and Tachmazidou, Ioanna and Klump, K.L and Treasure, J and Lewis, Cathryn and Schmidt, U and Tozzi, F and Iezebrink, K and Gorwood, P and Kas, Martien and Favaro, A and Santonastaso, P and Fernández-Aranda, F and Gratacos, M and Rybakowski, F and Dmitrzak-Weglarz, M and Kaprio, J and Keski-Rahkonen, A and Raevuori-Helkamaa, A and Furth, Eric and Slof-Op’t Landt, M.C.T and Hudson, J.I and Kaprio, Jaakko and Knudsen, G.P.S and Monteleone, P and Kaplan, A.S and Karwautz, A and Li, D and Komaki, G and Ando, T and Inoko, Hidetoshi and Esko, T and Fischer, Krista and Männik, K and Metspalu, A and Baker, J.H and Cone, R.D and Esko, Tõnu and DeSocio, J.E and Hilliard, C.E and O’Toole, J.K and Pantel, J and Szatkiewicz, J.P and Taico, C and Zerwas, S and Trace, S.E and Davis, Oliver S and Helder, S and Bühren, K and Burghardt, R and Imgart, H and Scherag, Ane and Boni, C and Ramoz, N and Versini, A and Danner, U.N and de Kove, C and Heniks, J and Koeleman, B.P.C and Ophoff, Roel and Strengman, Eric and Bruson, A and Clementi, Maurizio and Degortes, D and ... and WTCCC3 and GCAN and Children's Hosp Philadelphia and GIANT and GIANT, SFA Grant, EGG and GCAN, WTCCC3 and Price Foundation Collaborative Group, Children’s Hospital of Philadelphia/Price Foundation
Molecular psychiatry, ISSN 1359-4184, 02/2017, Volume 22, Issue 2, pp. 192 - 201
Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Psychiatry | Science & Technology | Obesity | Cross-disorder | Shared | Eating disorder | Loci | Bulimia nervosa
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6. Full Text Rare coding variants and X-linked loci associated with age at menarche
by Lunetta, Kathryn L and Day, Felix R and Sulem, Patrick and Ruth, Katherine S and Tung, Joyce Y and Hinds, David A and Esko, Tonu and Elks, Cathy E and Altmaier, Elisabeth and He, Chunyan and Huffman, Jennifer E and Mihailov, Evelin and Porcu, Eleonora and Robino, Antonietta and Rose, Lynda M and Schick, Ursula M and Stolk, Lisette and Teumer, Alexander and Thompson, Deborah J and Traglia, Michela and Wang, Carol A and Yerges-Armstrong, Laura M and Antoniou, Antonis C and Barbieri, Caterina and Coviello, Anea D and Cucca, Francesco and Demerath, Ellen W and Dunning, Alison M and Gandin, Ilaria and Grove, Megan L and Gudbjartsson, Daniel F and Hocking, Lynne J and Hofman, Albert and Huang, Jinyan and Jackson, Rebecca D and Karasik, David and Kriebel, Jennifer and Lange, Ethan M and Lange, Leslie A and Langenberg, Claudia and Li, Xin and Luan, Jian'an and Maegi, Reedik and Morrison, Alanna C and Padmanabhan, Sandosh and Pirie, Ailith and Polasek, Ozren and Porteous, David and Reiner, Alex P and van der Schouw, Yvonne T
Nature communications, ISSN 2041-1723, 08/2015, Volume 6
METAANALYSIS | LAMB2 | SUSCEPTIBILITY LOCI | MUTATIONS | IDENTIFICATION | CANCER | GENOME-WIDE ASSOCIATION
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7. Full Text Genetic determinants of serum testosterone concentrations in men
by Ohlsson, Claes and Wallaschofski, Henri and Lunetta, Kathryn and Stolk, Lisette and Perry, John and Koster, Annemarie and Petersen, A.K and Eriksson, Joel and Lehtimäki, Terho and Huhtaniemi, Ilpo and Hammond, Geoffrey and Maggio, Marcello and Coviello, Anea and Ferrucci, Luigi and Heier, Margit and Hofman, Albert and Holliday, Kate and Jansson, J.O and Kähönen, Mika and Karasik, David and Karlsson, Magnus and Kiel, Douglas and Liu, YongMei and Ljunggren, Ö and Lorentzon, Mattias and Lyytikäinen, Leo-Pekka and Meitinger, Thomas and Mellström, Dan and Melzer, David and Miljkovic, Iva and Nauck, Matthias and Nilsson, Maria and Penninx, Brenda and Pye, Stephen and Vasan, Ramachanan Srini and Reincke, Martin and Rivadeneira Ramirez, Fernando and Tajar, Abdelouahid and Teumer, Alexander and Uitterlinden, Ané and Ulloor, Jagadish and Viikari, Jorma and Völker, Uwe and Völzke, Henry and Wichmann, Heinz Erich and Wu, T.-S and Zhuang, W.V and Ziv, Elad and Raitakari, Olli and Bidlingmaier, Martin and Harris, Tamara and Murray, Anna and Jong, Frank and Murabito, Joanne and Bhasin, Shalender and Vandenput, Liesbeth and Haring, Robin and EMAS Study Grp and EMAS Study Group and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin and Institute of Neuroscience and Physiology, Department of Physiology and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institutionen för medicin, avdelningen för klinisk prövning och entreprenörskap and Institute of Medicine, Department of Clinical Trials and Entrepreneurship and Institutionen för neurovetenskap och fysiologi, sektionen för fysiologi and Institute of Medicine, Department of Internal Medicine
PLoS genetics, ISSN 1553-7390, 10/2011, Volume 7, Issue 10, pp. e1002313 - e1002313
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Body Mass Index | Genome-Wide Association Study | Chromosomes, Human, X - genetics | Humans | Middle Aged | Sex Hormone-Binding Globulin - genetics | Male | Alleles | Aged, 80 and over | Adult | Polymorphism, Single Nucleotide | Testosterone - blood | Nuclear Proteins - genetics | Physiological aspects | Testosterone | Promoters (Genetics) | Research | Health aspects | Index Medicus | Endokrinologi och diabetes | Endocrinology and Diabetes | Heart | Mortality | Colleges & universities | Genomes | Grants | Medicine | Confidence intervals | Mens health | Androgens | Education | Men | Aging | Gene loci
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8. Full Text A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone-Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation
by Coviello, Anea D and Haring, Robin and Wellons, Melissa and Vaidya, Dhananjay and Lehtimaki, Terho and Keildson, Sarah and Lunetta, Kathryn L and He, Chunyan and Fornage, Myriam and Lagou, Vasiliki and Mangino, Massimo and Onland-Moret, Charlotte N and Chen, Brian and Eriksson, Joel and Garcia, Melissa E and Mei, Yong and Koster, Annemarie and Lohman, Kurt K and Lyytikainen, Leo-Pekka and Petersen, Ann-Kristin and Prescott, Jennifer and Stolk, Lisette and Vandenput, Liesbeth and Wood, Anew R and Zhuang, Wei Vivian and Ruokonen, Aimo and Hartikainen, Anna-Liisa and Pouta, Anneli and Bandinelli, Stefania and Biffar, Reiner and