X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
chemistry (10) 10
heterocyclic compounds (10) 10
metallurgy (10) 10
organic chemistry (10) 10
human necessities (7) 7
hygiene (7) 7
medical or veterinary science (7) 7
preparations for medical, dental, or toilet purposes (7) 7
specific therapeutic activity of chemical compounds ormedicinal preparations (6) 6
index medicus (5) 5
humans (4) 4
chemistry, medicinal (3) 3
crystallography, x-ray (3) 3
dogs (3) 3
ligands (3) 3
models, molecular (3) 3
protein binding (3) 3
retirement (3) 3
administration, oral (2) 2
article (2) 2
design (2) 2
drug design (2) 2
ezh2 (2) 2
female (2) 2
male (2) 2
police dogs (2) 2
royalty (2) 2
structure-activity relationship (2) 2
2 brothers (1) 1
abridged index medicus (1) 1
activation (1) 1
active-site (1) 1
acyclic or carbocyclic compounds (1) 1
acyclic, carbocyclic or heterocyclic compounds containingelements other than carbon, hydrogen, halogen, oxygen, nitrogen,sulfur, selenium or tellurium (1) 1
adolescent (1) 1
adult (1) 1
aged (1) 1
aicardi goutieres syndrome (1) 1
aminopyridines - chemical synthesis (1) 1
aminopyridines - chemistry (1) 1
aminoquinolines - chemical synthesis (1) 1
aminoquinolines - chemistry (1) 1
amyloid precursor protein (1) 1
amyloid precursor protein secretases - antagonists & inhibitors (1) 1
amyloid precursor protein secretases - chemistry (1) 1
androgen receptor antagonists - metabolism (1) 1
androgen receptor antagonists - pharmacology (1) 1
androgens (1) 1
androgens - metabolism (1) 1
androgens - pharmacology (1) 1
animals (1) 1
antagonists (1) 1
anti-androgens (1) 1
antidepressants (1) 1
antidepressive agents (1) 1
antineoplastic agents - chemistry (1) 1
aspartic acid endopeptidases - antagonists & inhibitors (1) 1
aspartic acid endopeptidases - chemistry (1) 1
awards & honors (1) 1
bace-1 inhibitors (1) 1
basal ganglia (1) 1
basal ganglia diseases (1) 1
basal ganglia diseases - cerebrospinal fluid (1) 1
basal ganglia diseases - genetics (1) 1
basal ganglia diseases - pathology (1) 1
binding domain (1) 1
binding sites (1) 1
binding-affinity (1) 1
biochemistry & molecular biology (1) 1
biological availability (1) 1
bone (1) 1
brain (1) 1
brain - pathology (1) 1
calcinosis (1) 1
calcinosis - genetics (1) 1
calcinosis - pathology (1) 1
cerebrospinal-fluid lymphocytosis (1) 1
chaperone (1) 1
chilblains (1) 1
chilblains - genetics (1) 1
chilblains - pathology (1) 1
child (1) 1
child, preschool (1) 1
classification (1) 1
clinical trials (1) 1
congenital infection (1) 1
controlled study (1) 1
convulsions & seizures (1) 1
corporate sponsorship (1) 1
crystal-structure (1) 1
databases, factual (1) 1
degradation (1) 1
depression (1) 1
depression/epidemiology (1) 1
dna mutational analysis (1) 1
donations (1) 1
double-blind method (1) 1
drug discovery (1) 1
drug overdose (1) 1
enzalutamide resistance (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


by Rice, Gillian and Patrick, Teresa and Parmar, Rekha and Taylor, Claire F and Aeby, Alec and Aicardi, Jean and Artuch, Rafael and Montalto, Simon Attard and Bacino, Carlos A and Barroso, Bruno and Baxter, Peter and Benko, Willam S and Bergmann, Carsten and Bertini, Enrico and Biancheri, Roberta and Blair, Edward M and Blau, Nenad and Bonthron, David T and Briggs, Tracy and Brueton, Louise A and Brunner, Han G and Burke, Christopher J and Carr, Ian M and Carvalho, Daniel R and Chandler, Kate E and Christen, Hans-Jürgen and Corry, Peter C and Cowan, Frances M and Cox, Helen and D’Arrigo, Stefano and Dean, John and De Laet, Corinne and De Praeter, Claudine and Déry, Catherine and Ferrie, Colin D and Flintoff, Kim and Frints, Suzanna G.M and Garcia-Cazorla, Angels and Gener, Blanca and Goizet, Cyril and Goutières, Françoise and Green, Andrew J and Guët, Agnès and Hamel, Ben C.J and Hayward, Bruce E and Heiberg, Arvid and Hennekam, Raoul C and Husson, Marie and Jackson, Andrew P and Jayatunga, Rasieka and Jiang, Yong-Hui and Kant, Sarina G and Kao, Amy and King, Mary D and Kingston, Helen M and Klepper, Joerg and van der Knaap, Marjo S and Kornberg, Andrew J and Kotzot, Dieter and Kratzer, Wilfried and Lacombe, Didier and Lagae, Lieven and Landrieu, Pierre Georges and Lanzi, Giovanni and Leitch, Andrea and Lim, Ming J and Livingston, John H and Lourenco, Charles M and Lyall, E. G. Hermione and Lynch, Sally A and Lyons, Michael J and Marom, Daphna and McClure, John P and McWilliam, Robert and Melancon, Serge B and Mewasingh, Leena D and Moutard, Marie-Laure and Nischal, Ken K and Østergaard, John R and Prendiville, Julie and Rasmussen, Magnhild and Rogers, R. Curtis and Roland, Dominique and Rosser, Elisabeth M and Rostasy, Kevin and Roubertie, Agathe and Sanchis, Amparo and Schiffmann, Raphael and Scholl-Bürgi, Sabine and Seal, Sunita and Shalev, Stavit A and Corcoles, C. Sierra and Sinha, Gyan P and Soler, Doriette and Spiegel, Ronen and Stephenson, John B.P and Tacke, Uta and Tan, Tiong Yang and Till, Marianne and Tolmie, John L and ...
The American Journal of Human Genetics, ISSN 0002-9297, 2007, Volume 81, Issue 4, pp. 713 - 725
Journal Article
Journal Article
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 11/2018, Volume 13, Issue 11, pp. 3131 - 3141
B-cell lymphoma 6 (BCL6) inhibition is a promising mechanism for treating hematological cancers but high quality chemical probes are necessary to evaluate its... 
REPRESSION | ROLES | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | N-COR | DEGRADATION | INHIBITOR | EXPRESSION | EZH2
Journal Article
by Dennis, Martin and Mead, Gillian and Mead, Denise and Forbes, John and Graham, Julie and Graham, Susan and Graham, Libby and Graham, Catriona and Hackett, Maree and Hankey, Graeme J and House, Allan and Lewis, Stephanie and Lundström, Erik and Sandercock, Peter and Innes, Karen and Williams, Carol and Williams, Sandra and Williams, Rhys and Williams, Richard and Williams, Rebecca and Williams, Max and Williams, Sarah and Drever, Jonathan and Mcgrath, Aileen and Deary, Ann and Fraser, Greig and Fraser, Ruth and Anderson, Rosemary and Walker, Rachel and Walker, Elaine and Walker, Pauli and Walker, Susannah and Perry, David and Perry, Jack and Mcgill, Connor and Buchanan, David and Chun, Yvonne and Dinsmore, Lynn and Maschauer, Emma and Barugh, Amanda and Mikhail, Shadia and Blair, Gordon and Hoeritzauer, Ingrid and Scott, Jon and Scott, Rhona and Scott, Maggie and Lawrence, Tara and Lawrence, Katherine and Shaw, Alison and Williamson, Sue and Williamson, Judith and Burgess, David and Burgess, Seona and Burgess, Laura and Macleod, Fiona and Macleod, Malcolm and Macleod, Mary Joan and Morales, Dan and Sullivan, Frank and Brady, Marian and French, Ray and Van Wijck, Frederike and Watkins, Caroline and Proudfoot, Fiona and Skwarski, Joanna and Mcgowan, Diane and Murphy, Peter and Murphy, Rachael and Rutherford, William and Mccormick, Katrina and Buchan, Ruaridh and Macraild, Allan and Paulton, Ruth and Fazal, Adnan and Taylor, Vicky and Taylor, Caroline and Taylor, Pat and Parakramawansha, Ruwan and Hunter, Neil and Hunter, Nadia and Bamford, Elizabeth and Bamford, John and Waugh, Darren and Waugh, Dean and Veraque, Emelda and Bedford, Caroline and Bedford, Elizabeth and Kambafwile, Mary and Idrovo, Luis and Makawa, Linetty and Smalley, Paula and Randall, Marc and Thirugnana-Chandran, Tharani and Hassan, Hanna and Hassan, Muhammad and Hassan, Ahamad and Vowden, Richard and Jackson, Samantha and Jackson, Tracy and Jackson, Linda and ... and FOCUS Trial Collaboration
The Lancet, ISSN 0140-6736, 01/2019, Volume 393, Issue 10168, pp. 265 - 274
Journal Article
by Rice, Gillian and Patrick, Teresa and Parmar, Rekha and Taylor, Claire F and Aeby, Alec and Aicardi, Jean and Artuch, Rafael and Montalto, Simon Attard and Bacino, Carlos A and Barroso, Bruno and Baxter, Peter and Benko, Willam S and Bergmann, Carsten and Bertini, Enrico and Biancheri, Roberta and Blair, Edward M and Blau, Nenad and Bonthron, David T and Briggs, Tracy and Brueton, Louise A and Brunner, Han G and Burke, Christopher J and Carr, Ian M and Carvalho, Daniel R and Chandler, Kate E and Christen, Hans-Juergen and Corry, Peter C and Cowan, Frances M and Cox, Helen and D'Arrigo, Stefano and Dean, John and De laet, Corinne and De Praeter, Claudine and Dery, Catherine and Ferrie, Colin D and Flintoff, Kim and Frints, Suzanna G. M and Garcia-Cazorla, Angels and Gener, Blanca and Goizet, Cyril and Goutieres, Francoise and Green, Anew J and Gueet, Agnes and Hamel, Ben C. J and Hayward, Bruce E and Heiberg, Arvid and Hennekam, Raoul C and Husson, Marie and Jackson, Anew P and Jayatunga, Rasieka and Jiang, Yong-Hui and Kant, Sarina G and Kao, Amy and King, Mary D and Kingston, Helen M and Klepper, Joerg and van der Knaap, Marjo S and Kornberg, Anew J and Kotzot, Dieter and Kratzer, Wilfried and Lacombe, Didier and Lagae, Lieven and Lanieu, Pierre Georges and Lanzi, Giovanni and Leitch, Anea and Lim, Ming J and Livingston, John H and Lourenco, Charles M and Lyall, E. G. Hermione and Lynch, Sally A and Lyons, Michael J and Marom, Daphna and McClure, John P and McWilliam, Robert and Melancon, Serge B and Mewasingh, Leena D and Moutard, Marie-Laure and Nischal, Ken K and Ostergaard, John R and Prendiville, Julie and Rasmussen, Magnhild and Rogers, R. Curtis and Roland, Dominique and Rosser, Elisabeth M and Rostasy, Kevin and Roubertie, Agathe and Sanchis, Amparo and Schiffmann, Raphael and Scholl-Buergi, Sabine and Seal, Sunita and Shalev, Stavit A and Corcoles, C. Sierra and Sinha, Gyan P and Soler, Doriette and Spiegel, Ronen and Stephenson, John B. P and Tacke, Uta and Tan, Tiong Yang and Till, Marianne and Tolmie, John L and ...
American Journal of Human Genetics, ISSN 0002-9297, 10/2007, Volume 81, Issue 4, pp. 713 - 725
Aicardi-Goutieres syndrome (AGS) is a genetic encephalopathy whose clinical features mimic those of acquired in utero viral infection. AGS exhibits locus... 
Journal Article
08/2009
The invention provides a compound for use as an inhibitor of Hsp90, the compound having the formula (I): or salts, tautomers, solvates or N-oxides thereof;... 
METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
10/2007
The invention provides a compound for use as an inhibitor of Hsp90, the compound having the formula (I): or salts, tautomers, solvates or N-oxides thereof;... 
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS
Patent
11/2006
The invention provides a compound for use as an inhibitor of Hsp90, the compound having the formula (I): or salts, tautomers, solvates or N-oxides thereof;... 
METALLURGY | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS
Patent