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British Journal of Clinical Pharmacology, ISSN 0306-5251, 02/2019, Volume 85, Issue 2, p. 304
Interleukin (IL)-7 signalling modulates T cell activity and is implicated in numerous autoimmune diseases. The present study investigated the safety,... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 4447 - 4447
B-cell maturation antigen (BCMA) is upregulated at the terminal stages of plasma cell (PC) differentiation, and is expressed on normal and malignant PC. Apart... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 877 - 877
Abstract B cell maturation antigen (BCMA), which is highly expressed on malignant plasma cells in human multiple myeloma (MM), has not been effectively... 
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2010, Volume 185, Issue 7, pp. 3990 - 4003
Depletion of CD20+ B cells has been related to reduced clinical activity in relapsing-remitting multiple sclerosis. The underlying mechanism is not understood,... 
Journal Article
British Journal of Haematology, ISSN 0007-1048, 09/2016, Volume 174, Issue 6, pp. 911 - 922
Journal Article
Blood, ISSN 0006-4971, 11/2009, Volume 114, Issue 22, pp. 1725 - 1725
Abstract Abstract 1725 Poster Board I-751 Introduction CD20 represents a well established target for immunotherapy of B-cell malignancies such as follicular... 
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 02/2019, Volume 85, Issue 2, pp. 304 - 315
Aim Interleukin (IL)‐7 signalling modulates T cell activity and is implicated in numerous autoimmune diseases. The present study investigated the safety,... 
pharmacokinetics | immunology | pharmacodynamics | drug safety | monoclonal antibodies | SURVIVAL | PRIMARY SJOGRENS-SYNDROME | TH17 CYTOKINE PRODUCTION | SALIVARY-GLANDS | CD8 T-CELLS | INTERLEUKIN-7 | IL-7 | CONCISE GUIDE | PHARMACOLOGY & PHARMACY | BLOCKADE | EXPRESSION | Original
Journal Article
Journal of neuropathology and experimental neurology, ISSN 0022-3069, 11/2011, Volume 70, Issue 11, pp. 992 - 1005
This study investigated the effect of CD20-positive B-cell depletion on central nervous system (CNS) white and gray matter pathology in experimental autoimmune... 
Multiple sclerosis | MULTIPLE-SCLEROSIS LESIONS | ACTIVATION | Callithrix jacchus | Experimental autoimmune encephalomyelitis | Rituximab | Ofatumumab | CALLITHRIX-JACCHUS | CORTICAL-LESIONS | UMCG Approved | MYELIN/OLIGODENDROCYTE GLYCOPROTEIN | B cell | NONHUMAN PRIMATE MODEL | Demyelination | MONOCLONAL-ANTIBODIES | HUMAN CD20 | T-CELLS | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | Calgranulin B - metabolism | Humans | Myelin Proteins - adverse effects | Brain - metabolism | Encephalomyelitis, Autoimmune, Experimental - chemically induced | Nerve Fibers, Myelinated - pathology | Freund's Adjuvant - adverse effects | Myelin Proteolipid Protein - metabolism | Statistics, Nonparametric | Histocompatibility Antigens Class II - metabolism | B-Lymphocytes - pathology | Disease Models, Animal | Antibodies - therapeutic use | Antigens, CD20 - immunology | Encephalomyelitis, Autoimmune, Experimental - pathology | Callithrix | Complement C9 - metabolism | Encephalomyelitis, Autoimmune, Experimental - drug therapy | Myelin-Oligodendrocyte Glycoprotein | Antigens, CD20 - metabolism | B-Lymphocytes - drug effects | Magnetic Resonance Imaging | Animals | Brain - pathology | Neurofilament Proteins - metabolism | Tetraspanin-29 - metabolism | Proteins | Studies | Pathology | Nutrition research | Nuclear magnetic resonance--NMR | Rodents | Ataxia | Laboratory animals
Journal Article
07/2018
샘플에서 BCMA의 발현을 측정함으로써 환자에서 다발성 골수종의 예후를 결정하는 방법이 제공된다. 또한 샘플에서 BCMA의 발현을 측정하고 BCMA에 결합하는 항원 결합 단백질의 유효량을 투여함으로써 다발성 골수종을 치료하는 방법이 제공된다. 또한 샘플에서 BCMA 발현을 측정하기... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES | ORGANIC CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | MEASURING | HUMAN NECESSITIES | TESTING | METALLURGY | PEPTIDES | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | CHEMISTRY | PHYSICS
Patent
Genetics in Medicine, ISSN 1098-3600, 10/2018, Volume 20, Issue 10, pp. 1175 - 1185
Journal Article
Blood, ISSN 0006-4971, 05/2014, Volume 123, Issue 20, pp. 3128 - 3138
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 06/2017, Volume 100, Issue 6, pp. 907 - 925
Journal Article
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