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1. Joan Miró
: catalogue raisonné des livres illustrés
by Cramer, Patrick
1989, 674, [3]
Miró, Joan, 1893-1983 Catalogues raisonnés
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2. Full Text Structural Molecular Biology—A Personal Reflection on the Occasion of John Kendrew's 100th Birthday
by Cramer, Patrick
Journal of Molecular Biology, ISSN 0022-2836, 08/2017, Volume 429, Issue 17, pp. 2603 - 2610
Here, I discuss the development and future of structural molecular biology, concentrating on the eukaryotic transcription machinery and reflecting on John... 
gene transcription | multiprotein complex | history of molecular biology | RNA polymerase II | integrated structural biology | RNA-POLYMERASE-II | PARTICLE CRYO-EM | RECOGNITION | CRYSTAL-STRUCTURE | ELONGATION COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOLUTION | CROSS-LINKING | TRANSCRIPTION INITIATION | ARCHITECTURE | MEDIATOR STRUCTURE | Crystallography, X-Ray - methods | Cryoelectron Microscopy - history | Molecular Biology - history | History, 21st Century | Crystallography, X-Ray - history | History, 20th Century | Protein Conformation | Transcription, Genetic | RNA Polymerase II - metabolism | Cryoelectron Microscopy - methods | Molecular Biology - methods | RNA Polymerase II - chemistry | Molecular biology | Genetic transcription | RNA | Genes | Index Medicus
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3. Full Text Comprehensive Characterization of Cancer Driver Genes and Mutations
by Bailey, Matthew and Bailey, Matthew H and Tokheim, Collin and Porta-Pardo, Eduard and Sengupta, Sohini and Bertrand, Denis and Weerasinghe, Amila and Colaprico, Antonio and Wendl, Michael C and Kim, Jaegil and Reardon, Brendan and Ng, Kwok-Shing and Ng, Patrick Kwok-Shing and Jeong, Kang Jin and Cao, Song and Wang, Jioajiao and Wang, Timothy and Wang, Zhining and Wang, Zixing and Wang, Fang and Wang, Linghua and Wang, Jing and Wang, Min and Gao, Qingsong and Gao, Jianjiong and Gao, Galen F and Liu, Xiuping and Liu, Jia and Liu, Wenbin and Liu, Yuexin and Liu, Eric Minwei and Mularoni, Loris and Rubio-Perez, Carlota and Nagarajan, Niranjan and Cortés-Ciriano, Isidro and Zhou, Wanding and Zhou, Daniel Cui and Liang, Wen-Wei and Liang, Han and Hess, Julian M and Hess, Julian and Yellapantula, Venkata D and Tamborero, David and Gonzalez-Perez, Abel and Suphavilai, Chayaporn and Ko, Jia Yu and Khurana, Ekta and Park, Joong-Won and Park, Peter J and Van Allen, Eliezer M and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Ju Dong and Yang, Hannah and Yang, Ian and Yang, Liming and Zenklusen, Jean C and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Zhang, Jiexin and Zhang, Jiashan (Julia) and Zhang, Lizhi and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Michael and Miller, Christopher A and Miller, Judy and Reynolds, Sheila and ... and Canc Genome Atlas Res Network and MC3 Working Grp and MC3 Working Group and Cancer Genome Atlas Research Network
Cell, ISSN 0092-8674, 04/2018, Volume 173, Issue 2, pp. 371 - 385.e18
Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced algorithms to identify drivers now exist, but systematic attempts to... 
structure analysis | mutations of clinical relevance | oncology | driver gene discovery | MELANOMA | VARIANTS | SIGNATURES | LANDSCAPE | MICROSATELLITE INSTABILITY | PD-1 BLOCKADE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PATTERNS | OPEN-LABEL | SOMATIC MUTATIONS | DISCOVERY | CELL BIOLOGY | Microsatellite Instability | Humans | Computational Biology | Databases, Genetic | Entropy | B7-H1 Antigen - genetics | Algorithms | Neoplasms - genetics | Neoplasms - immunology | Mutation | Neoplasms - pathology | Principal Component Analysis | Programmed Cell Death 1 Receptor - genetics | Index Medicus | Oncology | driver discovery
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4. Full Text Inference of gene regulation functions from dynamic transcriptome data
by Hillenbrand, Patrick and Maier, Kerstin C and Cramer, Patrick and Gerland, Ulrich
eLife, ISSN 2050-084X, 09/2016, Volume 5, Issue 2016
To quantify gene regulation, a function is required that relates transcription factor binding to DNA (input) to the rate of mRNA synthesis from a target gene... 
YEAST | CLN3 | MESSENGER-RNA SYNTHESIS | CELL-CYCLE TRANSCRIPTION | DEPENDENT TRANSCRIPTION | RECONSTRUCTION | BIOLOGY | G1 CYCLINS | CDK | FKH2P | FORKHEAD GENES | Gene Expression Regulation, Fungal | Transcription Factors - metabolism | Multigene Family | Saccharomyces cerevisiae - physiology | Cell Cycle | Time Factors | Saccharomyces cerevisiae - genetics | Gene Expression Profiling | Transcription Factors - genetics | Genetic regulation | Observations | Genetic transcription | Transcription factors | Yeast | Gene regulation | Genomics | Oscillations | Gene expression | Kinases | Proteins | Cell cycle | Protein expression | Titration | Deoxyribonucleic acid--DNA | CLB2 gene | Index Medicus
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5. Full Text Nucleosome-Chd1 structure and implications for chromatin remodelling
by Farnung, Lucas and Vos, Seychelle M and Wigge, Christoph and Cramer, Patrick
Nature, ISSN 0028-0836, 10/2017, Volume 550, Issue 7677, pp. 539 - 542
Chromatin-remodelling factors change nucleosome positioning and facilitate DNA transcription, replication, and repair(1). The conserved remodelling factor... 
TRANSLOCATION | COMPLEX | PROTEIN | MULTIDISCIPLINARY SCIENCES | BIOLOGY | RECOMBINANT HISTONES | CHROMODOMAIN | MECHANISMS | CONTAINS | CHD1 | BINDING | Nucleosomes - chemistry | Saccharomyces cerevisiae - ultrastructure | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Multiprotein Complexes - metabolism | Adenosine Triphosphatases - ultrastructure | Nucleosomes - ultrastructure | Saccharomyces cerevisiae Proteins - ultrastructure | Adenosine Triphosphatases - metabolism | Chromatin Assembly and Disassembly | Models, Molecular | Nucleosomes - metabolism | DNA - metabolism | DNA-Binding Proteins - chemistry | Saccharomyces cerevisiae - chemistry | Cryoelectron Microscopy | DNA-Binding Proteins - ultrastructure | Multiprotein Complexes - ultrastructure | DNA - chemistry | Multiprotein Complexes - chemistry | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Adenosine Triphosphatases - chemistry | Enzyme Activation | Histones - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Physiological aspects | Chromatin | Gene expression | Observations | Yeast | Transcription | Saccharomyces | DNA-directed RNA polymerase | Mimicry | DNA helicase | Proteins | Catalysis | Serrated yielding | Deoxyribonucleic acid--DNA | Binding | Translocation | Superhelical DNA | Ratcheting | Electron microscopy | Chromatin remodeling | Gyres | Lobes | DNA biosynthesis | Polymerase | Histone H4 | Ribonucleic acids | Loosening | Saccharomyces cerevisiae | Binding sites | Adenosine triphosphatase | RNA polymerase II | Pluripotency | Index Medicus
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6. Full Text Core Mediator structure at 3.4 Å extends model of transcription initiation complex
by Nozawa, Kayo and Schneider, Thomas R and Cramer, Patrick
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7653, pp. 248 - 251
Mediator is a multiprotein co-activator that binds the transcription pre-initiation complex (PIC) and regulates RNA polymerase (Pol) II. The Mediator head and... 
Schizosaccharomyces - ultrastructure | Schizosaccharomyces pombe Proteins - chemistry | Phosphorylation | Transcription Factors - chemistry | Mediator Complex - metabolism | Saccharomyces cerevisiae - genetics | Schizosaccharomyces - chemistry | Crystallography, X-Ray | Transcription Factor TFIIH - chemistry | RNA Polymerase II - metabolism | Protein Subunits - metabolism | Schizosaccharomyces - genetics | Transcription Factors, TFII - ultrastructure | Mediator Complex - chemistry | Mediator Complex - ultrastructure | Schizosaccharomyces pombe Proteins - metabolism | Transcription Initiation, Genetic | RNA Polymerase II - chemistry | Transcription Factor TFIIH - ultrastructure | Models, Molecular | Mediator Complex - genetics | Saccharomyces cerevisiae - chemistry | Cryoelectron Microscopy | Transcription Factors - metabolism | Transcription Factors, TFII - chemistry | Transcription Factor TFIIH - metabolism | Transcription Factors, TFII - metabolism | Protein Subunits - chemistry | Mutation | Genetic research | Research | Genetic transcription | RNA polymerases | Initiation complex | Head | Yeast | Architecture | Laboratories | RNA polymerase | Gene expression | Electron microscopy | Kinases | DNA-directed RNA polymerase | Molecular biology | Crystal structure | Index Medicus
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7. Full Text RNA polymerase I-Rrn3 complex at 4.8 Å resolution
by Engel, Christoph and Plitzko, Jürgen and Cramer, Patrick
Nature Communications, ISSN 2041-1723, 07/2016, Volume 7, Issue 1, pp. 12129 - 12129
Transcription of ribosomal DNA by RNA polymerase I (Pol I) requires the initiation factor Rrn3. Here we report the cryo-EM structure of the Pol I-Rrn3 complex... 
Cryoelectron Microscopy | Pol1 Transcription Initiation Complex Proteins - genetics | Pol1 Transcription Initiation Complex Proteins - metabolism | Protein Multimerization | Saccharomyces cerevisiae Proteins - metabolism | Pol1 Transcription Initiation Complex Proteins - chemistry | RNA Polymerase I - metabolism | RNA Polymerase I - chemistry | RNA Polymerase I - genetics | Saccharomyces cerevisiae Proteins - chemistry | Index Medicus
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8. Full Text Structure and function of the initially transcribing RNA polymerase II-TFIIB complex
by Sainsbury, Sarah and Niesser, Jürgen and Cramer, Patrick
Nature, ISSN 0028-0836, 01/2013, Volume 493, Issue 7432, pp. 437 - 440
The general transcription factor (TF) IIB is required for RNA polymerase (Pol) II initiation and extends with its B-reader element into the Pol II active... 
ANGSTROM RESOLUTION | MECHANISM | INITIATION | TRANSCRIPTION FACTOR IIB | DNA | MULTIDISCIPLINARY SCIENCES | IN-VIVO | ARCHITECTURE | SACCHAROMYCES-CEREVISIAE | PREINITIATION COMPLEX | PROMOTER CLEARANCE | Protein Structure, Tertiary | Amino Acid Sequence | Biocatalysis | Transcription Factor TFIIB - metabolism | Transcription Factor TFIIB - chemistry | Models, Molecular | Molecular Sequence Data | Templates, Genetic | Crystallography, X-Ray | Structure-Activity Relationship | DNA - metabolism | RNA Polymerase II - metabolism | RNA, Messenger - metabolism | Protein Subunits - metabolism | DNA - genetics | RNA, Messenger - biosynthesis | Saccharomyces cerevisiae - enzymology | Protein Subunits - chemistry | Transcription Initiation, Genetic | RNA Polymerase II - chemistry | Physiological aspects | Transcription factors | RNA polymerases | Proteins | Enzymes | Mutation | RNA polymerase | Index Medicus
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9. Full Text Structure of transcribing mammalian RNA polymerase II
by Bernecky, Carrie and Herzog, Franz and Baumeister, Wolfgang and Plitzko, Jürgen M and Cramer, Patrick
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7587, pp. 551 - 554
RNA polymerase (Pol) II produces messenger RNA during transcription of protein-coding genes in all eukaryotic cells. The Pol II structure is known at high... 
ATOMIC-STRUCTURE | COMPLEX | PARTICLE ELECTRON CRYOMICROSCOPY | CRYOELECTRON MICROSCOPY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | RESOLUTION | ARCHITECTURE | EM STRUCTURE DETERMINATION | CRYO-EM | TRANSCRIPTION ELONGATION | Allosteric Regulation | Humans | RNA Polymerase II - ultrastructure | Templates, Genetic | DNA - ultrastructure | RNA Polymerase II - metabolism | RNA, Messenger - ultrastructure | Protein Subunits - metabolism | RNA, Messenger - biosynthesis | Nucleic Acids - chemistry | Cattle | RNA Polymerase II - chemistry | Protein Structure, Tertiary | Catalytic Domain | RNA, Messenger - genetics | Models, Molecular | Nucleic Acids - metabolism | DNA - metabolism | Amino Acid Motifs | Transcription Elongation, Genetic | Cryoelectron Microscopy | DNA - genetics | Animals | Saccharomyces cerevisiae - enzymology | Protein Subunits - chemistry | Physiological aspects | Research | Genetic transcription | Structure | RNA polymerases | Studies | Enzymes | Crystallization | Crystals | RNA polymerase | Mammals | Ribonucleic acid--RNA | Deoxyribonucleic acid--DNA | Crystal structure | Index Medicus
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