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The New England Journal of Medicine, ISSN 0028-4793, 12/2013, Volume 369, Issue 24, pp. 2313 - 2323
Journal Article
by Ehret, Georg B and Ferreira, Teresa and Chasman, Daniel I and Jackson, Anne U and Schmidt, Ellen M and Johnson, Toby and Thorleifsson, Gudmar and Luan, Jian'an and Donnelly, Louise A and Kanoni, Stavroula and Petersen, Ann-Kristin and Pihur, Vasyl and Strawbridge, Rona J and Shungin, Dmitry and Hughes, Maria F and Meirelles, Osorio and Kaakinen, Marika and Bouatia-Naji, Nabila and Kristiansson, Kati and Shah, Sonia and Kleber, Marcus E and Guo, Xiuqing and Lyytikäinen, Leo-Pekka and Fava, Cristiano and Eriksson, Niclas and Nolte, Ilja M and Magnusson, Patrik K and Salfati, Elias L and Rallidis, Loukianos S and Theusch, Elizabeth and Smith, Anew J. P and Folkersen, Lasse and Witkowska, Kate and Pers, Tune H and Joehanes, Roby and Kim, Stuart K and Lataniotis, Lazaros and Jansen, Rick and Johnson, Anew D and Warren, Helen and Kim, Young Jin and Zhao, Wei and Wu, Ying and Tayo, Bamidele O and Bochud, Murielle and Absher, Devin and Adair, Linda S and Amin, Najaf and Arking, Dan E and Axelsson, Tomas and Baldassarre, Damiano and Balkau, Beverley and Bandinelli, Stefania and Barnes, Michael R and Barroso, Inês and Bevan, Stephen and Bis, Joshua C and Bjornsdottir, Gyda and Boehnke, Michael and Boerwinkle, Eric and Bonnycastle, Lori L and Boomsma, Dorret I and Bornstein, Stefan R and Brown, Morris J and Burnier, Michel and Cabrera, Claudia P and Chambers, John C and Chang, I.-Shou and Cheng, Ching-Yu and Chines, Peter S and Chung, Ren-Hua and Collins, Francis S and Connell, John M and Döring, Angela and Dallongeville, Jean and Danesh, John and de Faire, Ulf and Delgado, Graciela and Dominiczak, Anna F and Doney, Alex S. F and nos, Fotios and Edkins, Sarah and Eicher, John D and Elosua, Roberto and Enroth, Stefan and Erdmann, Jeanette and Eriksson, Per and Esko, Tonu and Evangelou, Evangelos and Evans, Alun and Fall, Tove and Farrall, Martin and Felix, Janine F and Ferrières, Jean and Ferrucci, Luigi and Fornage, Myriam and Forrester, Terrence and Franceschini, Nora and Franco, Oscar H and Franco-Cereceda, Anders and ... and CHARGE-HF Consortium and Wellcome Trust Case Control Consor and CHARGE-EchoGen Consortium and Wellcome Trust Case Control Consortium and CHARGE-EchoGen consortium and CHARGE-HF consortium and Medicinska fakulteten and Avdelningen för medicin and Umeå universitet and Medicin and Institutionen för odontologi and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Näringsforskning
Nature genetics, ISSN 1061-4036, 2016, Volume 48, Issue 10, pp. 1171 - 1184
Journal Article
by Pattaro, Cristian and Teumer, Alexander and Gorski, Mathias and Chu, Auey Y and Li, Man and Mijatovic, Vladan and Garnaas, Maija and Tin, Aienne and Sorice, Rossella and Li, Yong and Taliun, Daniel and Olden, Matthias and Foster, Meredith and Yang, Qiong and Chen, Ming-Huei and Pers, Tune H and Johnson, Anew D and Ko, Yi-An and Fuchsberger, Christian and Tayo, Bamidele and Nalls, Michael and Feitosa, Mary F and Isaacs, Aaron and Dehghan, Abbas and d'Adamo, Pio and Adeyemo, Adebowale and Dieffenbach, Aida Karina and Zonderman, Alan B and Nolte, Ilja M and van der Most, Peter J and Wright, Alan F and Shuldiner, Alan R and Morrison, Alanna C and Hofman, Albert and Smith, Albert V and isbach, Albert W and Franke, Ane and Uitterlinden, Ane G and Metspalu, Anes and Tonjes, Anke and Lupo, Antonio and Robino, Antonietta and Johansson, Asa and Demirkan, Ayse and Kollerits, Barbara and Freedman, Barry I and Ponte, Belen and Oostra, Ben A and Paulweber, Bernhard and Kraemer, Bernhard K and Mitchell, Braxton D and Buckley, Brendan M and Peralta, Carmen A and Hayward, Caroline and Helmer, Catherine and Rotimi, Charles N and Shaffer, Christian M and Mueller, Christian and Sala, Cinzia and van Duijn, Cornelia M and Saint-Pierre, Aude and Ackermann, Daniel and Shriner, Daniel and Ruggiero, Daniela and Toniolo, Daniela and Lu, Yingchang and Cusi, Daniele and Czamara, Darina and Ellinghaus, David and Siscovick, David S and Ruderfer, Douglas and Gieger, Christian and Grallert, Harald and Rochtchina, Elena and Atkinson, Elizabeth J and Holliday, Elizabeth G and Boerwinkle, Eric and Salvi, Erika and Bottinger, Erwin P and Murgia, Federico and Rivadeneira, Fernando and Ernst, Florian and Kronenberg, Florian and Hu, Frank B and Navis, Gerjan J and Curhan, Gary C and Ehret, George B and Homuth, Georg and Coassin, Stefan and Thun, Gian-Ani and Pistis, Giorgio and Gambaro, Giovanni and Malerba, Giovanni and Montgomery, Grant W and Eiriksdottir, Gudny and Jacobs, Gunnar and Li, Guo and Wichmann, H-Erich and Campbell, Harry and Schmidt, Helena and ... and CARDIOGRAM and ICBP Consortium and AGEN Consortium and CHARGe-Heart Failure Grp and ECHOGen Consortium and CHARGe-Heart Failure Group and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet and Medicinsk genetik och genomik
Nature Communications, ISSN 2041-1723, 01/2016, Volume 7, Issue 1, p. 10023
Journal Article
Journal Article
Japanese Journal of Thrombosis and Hemostasis, ISSN 0915-7441, 2016, Volume 27, Issue 6, pp. 665 - 677
Introduction: Recombinant factor VIII Fc fusion protein (rFVIIIFc) was safe and efficacious for control and prevention of bleeding in the multinational Phase 3... 
pharmacokinetics | haemophilia A | bleeding | recombinant factor VIII Fc fusion protein | factor VIII
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1414 - 1414
Abstract Background: Factor VIII (FVIII) prophylaxis is the standard of care for patients with hemophilia A; however, conventional FVIII products usually... 
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 01/2016, Volume 116, Issue 7, pp. 1 - 8
Summary The Phase 3 A-LONG and Kids A-LONG studies demonstrated the prolonged half-life of rFVIIIFc compared with rFVIII, and the safety and efficacy of... 
Coagulation and Fibrinolysis | Haemophilia A | Haemostasis | Phase 3 trial | Surgery | Factor VIII | KNEE | EFFICACY | SAFETY | HIP-ARTHROPLASTY | haemophilia A | ORTHOPEDIC-SURGERY | TRANSFUSION | haemostasis | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | factor VIII | surgery
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 1083 - 1083
Abstract Background: The phase 3 B-LONG (adults/adolescents ≥12 years of age) and Kids B-LONG (children <12 years of age) studies demonstrated the safety and... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1413 - 1413
Abstract Background: Prophylactic replacement of coagulation factor VIII (FVIII) is the standard of care for patients with hemophilia A; however, prophylaxis... 
Journal Article
British Journal of Haematology, ISSN 0007-1048, 01/2015, Volume 168, Issue 1, pp. 124 - 134
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 1087 - 1087
Abstract Background: Prophylactic replacement of coagulation factor VIII (FVIII) is the standard of care for patients with hemophilia A; however, prophylactic... 
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 1494 - 1494
Abstract Background: Initiation of prophylactic factor VIII (FVIII) therapy at a young age is recommended for the prevention of bleeds and associated... 
Journal Article