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Nature, ISSN 0028-0836, 01/2015, Volume 517, Issue 7533, pp. 205 - 208
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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 49, pp. 19611 - 19616
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 1978, p. 269
Stable isotope tracing allows a metabolic substrate to be followed through downstream biochemical reactions, thereby providing unparalleled insights into the... 
Journal Article
Science, ISSN 0036-8075, 5/2009, Volume 324, Issue 5930, pp. 1076 - 1080
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 493 - 498
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 22, pp. 8882 - 8887
Journal Article
Nature, ISSN 0028-0836, 07/2018, Volume 559, Issue 7712, pp. 125 - 129
Somatic mutations in the isocitrate dehydrogenase 2 gene (IDH2) contribute to the pathogenesis of acute myeloid leukaemia (AML) through the production of the... 
LUNG-CANCER | CELLS | GEFITINIB | MUTANT IDH2 | MULTIDISCIPLINARY SCIENCES | ACUTE MYELOID-LEUKEMIA | DIFFERENTIATION | (R)-2-HYDROXYGLUTARATE | ENASIDENIB | Triazines - therapeutic use | Humans | Glutarates - blood | Isocitrate Dehydrogenase - antagonists & inhibitors | Aminopyridines - chemistry | Aminopyridines - therapeutic use | Enzyme Inhibitors - chemistry | HEK293 Cells | Protein Multimerization - genetics | Leukemia, Myeloid, Acute - drug therapy | Female | Triazines - chemistry | Mutant Proteins - antagonists & inhibitors | Allosteric Site - genetics | Triazines - pharmacology | Allosteric Site - drug effects | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Mutant Proteins - genetics | Models, Molecular | Isocitrate Dehydrogenase - genetics | Leukemia, Myeloid, Acute - blood | Enzyme Inhibitors - therapeutic use | Disease Progression | Isoleucine - genetics | Drug Resistance, Neoplasm - genetics | Animals | Aminopyridines - pharmacology | Alleles | Glutamine - genetics | Glutarates - metabolism | Mice | Mutation | Clinical Trials, Phase I as Topic | Clinical Trials, Phase II as Topic | Drug Resistance, Neoplasm - drug effects | Leukemia, Myeloid, Acute - genetics | Antimitotic agents | Pharmaceutical research | Research | Drug resistance | Antineoplastic agents | Glutamine | Plasma | Pathogenesis | Leukemia | Lung cancer | Cloning | Neutrophils | Kinases | Cancer therapies | Patients | Proteins | Disease resistance | Allosteric properties | Inhibitors | Bone marrow | Dimers | Inhibition | Target acquisition | Isocitrate dehydrogenase | Isoleucine | Neutropenia | AG-120 | cancer metabolism | leukemia | AG-221 | metabolite | enasidenib | epigenetic | IDH1 | IDH2 | glioma | ivosidenib
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