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Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 24, pp. 2748 - 2750
In this issue of Blood , Zhang et al have uncovered that metformin, a first-line treatment for type 2 diabetes, can improve hematopoietic stem cell (HSC)... 
CELLS | ALDEHYDES | PROTEIN | HEMATOLOGY | PATHWAY | Inside
Journal Article
Journal Article
Nature, ISSN 0028-0836, 07/2011, Volume 475, Issue 7354, pp. 53 - 59
Reactive aldehydes are common carcinogens. They are also by-products of several metabolic pathways and, without enzymatic catabolism, may accumulate and cause... 
DNA-ADDUCTS | METABOLISM | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | FETAL ALCOHOL SYNDROME | ETHANOL | CHILDHOOD LEUKEMIA | KNOCKOUT MICE | ACETALDEHYDE | FANCONI-ANEMIA | CONSUMPTION | Embryo, Mammalian - drug effects | Acetaldehyde - metabolism | Clone Cells - drug effects | Teratogens - toxicity | Ethanol - toxicity | Fanconi Anemia Complementation Group D2 Protein - genetics | Weaning | Aldehyde Dehydrogenase, Mitochondrial | Male | DNA Repair - genetics | Aldehydes - metabolism | Aldehydes - antagonists & inhibitors | Fanconi Anemia Complementation Group D2 Protein - deficiency | Precursor Cell Lymphoblastic Leukemia-Lymphoma - chemically induced | Hematopoiesis - drug effects | Fetal Alcohol Spectrum Disorders - etiology | Gene Deletion | Aldehyde Dehydrogenase - deficiency | Embryo Loss - etiology | DNA Damage - genetics | Fanconi Anemia - pathology | Female | Fanconi Anemia - genetics | Aldehyde Dehydrogenase - metabolism | B-Lymphocytes - metabolism | Bone Marrow - drug effects | Cell Line | Cell Survival - drug effects | Aldehydes - toxicity | Bone Marrow - physiopathology | Ethanol - metabolism | Acetaldehyde - toxicity | Embryo Loss - chemically induced | Mice, Inbred C57BL | Aldehyde Dehydrogenase - genetics | Genes, Essential | Embryo, Mammalian - abnormalities | Pregnancy | B-Lymphocytes - drug effects | Animals | Embryo, Mammalian - embryology | Fanconi Anemia Complementation Group D2 Protein - metabolism | Bone Marrow - pathology | Chickens | Alleles | Mice | Precursor Cell Lymphoblastic Leukemia-Lymphoma - etiology | Teratogens - metabolism | Causes of | Research | Aldehydes | Health aspects | Fanconi's anemia | Mutation | DNA repair | Stem cells | Cancer
Journal Article
Journal Article
Journal Article
Medecine/Sciences, ISSN 0767-0974, 04/2013, Volume 29, Issue 4, pp. 361 - 364
Journal Article