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1. Full Text Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
by Shimada, Kenichi and Crother, Timothy R and Karlin, Justin and Dagvadorj, Jargalsaikhan and Chiba, Norika and Chen, Shuang and Ramanujan, V. Krishnan and Wolf, Andrea J and Vergnes, Laurent and Ojcius, David M and Rentsendorj, Altan and Vargas, Mario and Guerrero, Candace and Wang, Yinsheng and Fitzgerald, Katherine A and Underhill, David M and Town, Terrence and Arditi, Moshe
Immunity (Cambridge, Mass.), ISSN 1074-7613, 03/2012, Volume 36, Issue 3, pp. 401 - 414
Life Sciences & Biomedicine | Immunology | Science & Technology | Gene Expression | Inflammasomes - metabolism | Proto-Oncogene Proteins c-bcl-2 - immunology | DNA, Mitochondrial - metabolism | Oxidation-Reduction | Salmonella typhimurium - immunology | Salmonella typhimurium - pathogenicity | Signal Transduction | NLR Family, Pyrin Domain-Containing 3 Protein | Mice, Inbred C57BL | NF-kappa B - immunology | Macrophages - cytology | Mice, Knockout | DNA, Mitochondrial - immunology | Macrophages - metabolism | Animals | Apoptosis - immunology | Carrier Proteins - metabolism | Inflammasomes - immunology | Interleukin-1beta - biosynthesis | Mice | Proto-Oncogene Proteins c-bcl-2 - genetics | Carrier Proteins - immunology | Macrophages - immunology | Medical colleges | Cell death | DNA | Nucleosides | Mitochondrial DNA | Macrophages | Apoptosis | Microscopy | Colleges & universities | Software | Infections | Deoxyribonucleic acid--DNA | ATP | Index Medicus
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2. Full Text Immunological Consequences of Intestinal Fungal Dysbiosis
by Wheeler, Matthew L and Limon, Jose J and Bar, Agnieszka S and Leal, Christian A and Gargus, Matthew and Tang, Jie and Brown, Jordan and Funari, Vincent A and Wang, Hanlin L and Crother, Timothy R and Arditi, Moshe and Underhill, David M and Iliev, Iliyan D
Cell host & microbe, ISSN 1931-3128, 06/2016, Volume 19, Issue 6, pp. 865 - 873
Parasitology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Virology | Antifungal Agents - adverse effects | Fluconazole - pharmacology | Bacteria - drug effects | Hypersensitivity - immunology | Fluconazole - adverse effects | Drug Hypersensitivity - microbiology | Fungi - genetics | Fungi - immunology | Dysbiosis - immunology | Hypersensitivity - microbiology | Base Sequence | Colitis - immunology | Antifungal Agents - pharmacology | Dysbiosis - chemically induced | Fungi - drug effects | Mice, Inbred C57BL | Amphotericin B - pharmacology | Amphotericin B - adverse effects | Animals | Colitis - microbiology | Gastrointestinal Microbiome - drug effects | Intestines - microbiology | Drug Hypersensitivity - immunology | Mice | Gastrointestinal Microbiome - immunology | Dietary Supplements | Bacteria | Colitis | Microbiota (Symbiotic organisms) | Analysis | Antifungal agents | Index Medicus
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3. Full Text MD-2 as a possible therapeutic target for atherosclerosis
by Chen, Shuang and Crother, Timothy R
EBioMedicine, ISSN 2352-3964, 05/2020, Volume 55, pp. 102760 - 102760
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Index Medicus
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4. Full Text POPsicle for Fever! Cooling Down the Inflammasome
by Shimada, Kenichi and Crother, Timothy R and Arditi, Moshe
Immunity (Cambridge, Mass.), ISSN 1074-7613, 08/2015, Volume 43, Issue 2, pp. 213 - 215
Life Sciences & Biomedicine | Immunology | Science & Technology | Cryopyrin-Associated Periodic Syndromes - immunology | Animals | Inflammasomes - metabolism | Dendritic Cells - immunology | Humans | Macrophages, Peritoneal - immunology | Female | Monocytes - immunology | Ribonucleoproteins - metabolism | Peritonitis - immunology | Proteins | Mutation | Feedback | Rodents | Inflammatory diseases | Apoptosis | Index Medicus
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5. Full Text Loss of testosterone impairs anti-tumor neutrophil function
by Markman, Janet L and Porritt, Rebecca A and Wakita, Daiko and Lane, Malcolm E and Martinon, Daisy and Rivas, Magali Noval and Luu, Michael and Posadas, Edwin M and Crother, Timothy R and Arditi, Moshe
Nature communications, ISSN 2041-1723, 03/2020, Volume 11, Issue 1, pp. 1613 - 1613
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Deprivation | Phenotypes | Neutrophils | Melanoma | Sex | Sex differences | Metastasis | Metastases | Testosterone | Androgens | Evolutionary conservation | Gender aspects | Men | Prostate cancer | Prostate | Age | Immune system | Index Medicus
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6. Full Text Chlamydia and Lipids Engage a Common Signaling Pathway That Promotes Atherogenesis
by Chen, Shuang and Shimada, Kenichi and Crother, Timothy R and Erbay, Ebru and Shah, Prediman K and Arditi, Moshe
Journal of the American College of Cardiology, ISSN 0735-1097, 04/2018, Volume 71, Issue 14, pp. 1553 - 1570
atherosclerosis | myeloid differentiation factor 88 | Chlamydia pneumoniae | dendritic cells | Toll-like receptor 4 | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Chlamydophila Infections - complications | Immunohistochemistry | Atherosclerosis - immunology | Signal Transduction | Mice, Inbred C57BL | Chlamydophila Infections - metabolism | Chlamydophila Infections - immunology | Lipid Metabolism | Lipids | Male | Immunity, Innate | Atherosclerosis - metabolism | Mice, Knockout | Atherosclerosis - etiology | Chlamydophila pneumoniae - pathogenicity | Animals | Female | Mice | Disease Models, Animal | Atherogenesis | Adaptive systems | Crosstalk | Dyslipidemia | Infections | Vaccines | High fat diet | Proteins | Signal transduction | Sexually transmitted diseases | Chlamydia | Lymphocytes | Apolipoprotein E | Atherosclerosis | Toll-like receptors | Bone marrow | Aorta | Chimeras | Plaques | Immune system | CD11c antigen | Myeloid cells | Immune response | Cytokines | Dendritic cells | Inflammation | TLR4 protein | Cholesterol | Hemopoiesis | Studies | Signaling | Diet | Stromal cells | Arteriosclerosis | MyD88 protein | Laboratory animals | Acceleration | Dendritic structure | System effectiveness
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7. Full Text Lipopolysaccharide Induces Alveolar Macrophage Necrosis via CD14 and the P2X7 Receptor Leading to Interleukin-1α Release
by Dagvadorj, Jargalsaikhan and Shimada, Kenichi and Chen, Shuang and Jones, Heather D and Tumurkhuu, Gantsetseg and Zhang, Wenxuan and Wawrowsky, Kolja A and Crother, Timothy R and Arditi, Moshe
Immunity (Cambridge, Mass.), ISSN 1074-7613, 04/2015, Volume 42, Issue 4, pp. 640 - 653
Life Sciences & Biomedicine | Immunology | Science & Technology | Interleukin-1alpha - immunology | Macrophages, Alveolar - pathology | Calcium - metabolism | Humans | Capillary Permeability - immunology | Neutrophil Infiltration | Necrosis - pathology | Receptors, Purinergic P2X7 - genetics | Necrosis - immunology | Cadherins - immunology | Adenosine Triphosphate - metabolism | HEK293 Cells | Interleukin-1alpha - genetics | Cadherins - genetics | Receptors, Purinergic P2X7 - immunology | Macrophages, Alveolar - immunology | Neutrophils - pathology | Lung - pathology | Protein Precursors - genetics | Signal Transduction | Neutrophils - drug effects | Gene Expression Regulation | Neutrophils - immunology | Lipopolysaccharide Receptors - immunology | Mice, Transgenic | Protein Precursors - immunology | Acute Lung Injury - pathology | Necrosis - chemically induced | Endothelial Cells - immunology | Animals | Acute Lung Injury - chemically induced | Macrophages, Alveolar - drug effects | Lung - drug effects | Lipopolysaccharides - pharmacology | Lipopolysaccharide Receptors - genetics | Acute Lung Injury - immunology | Mice | Endothelial Cells - pathology | Intubation, Intratracheal | Lung - immunology | Endothelial Cells - drug effects | Index Medicus | endothelial cells | alveolar macrophage | Ca2+ influx | MyD88 | IL-1α | neutrophil | P2X7R | lung injury | necrosis | ARDS | ALI | sepsis | lung inflammation
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8. Full Text Innate immune responses to Chlamydia pneumoniae infection: role of TLRs, NLRs, and the inflammasome
by Shimada, Kenichi and Crother, Timothy R and Arditi, Moshe
Microbes and infection, ISSN 1286-4579, 11/2012, Volume 14, Issue 14, pp. 1301 - 1307
Chlamydia pneumoniae | Inflammasome | TLR | NLR | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Bacteriology | Vascular Diseases - immunology | Chlamydia Infections - immunology | Receptors, Cytoplasmic and Nuclear - immunology | Animals | Vascular Diseases - microbiology | Humans | Inflammasomes - immunology | Toll-Like Receptors - immunology | Immunity, Innate | Chlamydophila pneumoniae - immunology | Pneumonia | Immune response | Chlamydia | Bacterial pneumonia | Children | Health aspects | Public health | Diseases | Index Medicus | Infection | Pathogens | Immunity | inflammasome
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9. Full Text Emerging Role of IL-17 in Atherosclerosis
by Chen, Shuang and Crother, Timothy R and Arditi, Moshe
Journal of innate immunity, ISSN 1662-811X, 06/2010, Volume 2, Issue 4, pp. 325 - 333
Review | Innate and adaptive immunity | Atherosclerosis | IL-17 | Life Sciences & Biomedicine | Immunology | Science & Technology | Immunity, Innate - immunology | Interleukin-17 - metabolism | Animals | Atherosclerosis - immunology | Atherosclerosis - physiopathology | T-Lymphocytes, Helper-Inducer - immunology | Humans | Interleukin-17 - immunology | Interleukin-17 - genetics | Mice | T-Lymphocytes, Helper-Inducer - pathology | Adaptive Immunity - immunology | Index Medicus
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