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41. Full Text Antigen-Specific Adaptive Immunity to SARS-CoV-2 in Acute COVID-19 and Associations with Age and Disease Severity
by Rydyznski Moderbacher, Carolyn and Ramirez, Sydney I and Dan, Jennifer M and Grifoni, Alba and Hastie, Kathryn M and Weiskopf, Daniela and Belanger, Simon and Abbott, Robert K and Kim, Christina and Choi, Jinyong and Kato, Yu and Crotty, Eleanor G and Kim, Cheryl and Rawlings, Stephen A and Mateus, Jose and Tse, Long Ping Victor and Frazier, April and Baric, Ralph and Peters, Bjoern and Greenbaum, Jason and Ollmann Saphire, Erica and Smith, Davey M and Sette, Alessandro and Crotty, Shane
Cell (Cambridge), ISSN 0092-8674, 11/2020, Volume 183, Issue 4, pp. 996 - 1012.e19
Spike | CXCL10 | epitopes | CD4 | antibody | CD8 | coronavirus | neutralizing antibodies | T cells | IP-10 | adaptive immunity | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | CD8-Positive T-Lymphocytes - cytology | Pandemics | Humans | Middle Aged | Male | Antibodies, Viral - blood | Betacoronavirus - immunology | CD4-Positive T-Lymphocytes - immunology | COVID-19 | Young Adult | SARS-CoV-2 | Aged, 80 and over | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Cytokines - blood | Adaptive Immunity | Severity of Illness Index | Acute Disease | Betacoronavirus - isolation & purification | CD4-Positive T-Lymphocytes - cytology | Pneumonia, Viral - pathology | CD4-Positive T-Lymphocytes - metabolism | Betacoronavirus - metabolism | Coronavirus Infections - immunology | Pneumonia, Viral - immunology | Antigens, Viral - immunology | Coronavirus Infections - virology | Coronavirus Infections - pathology | Aged | CD8-Positive T-Lymphocytes - immunology | Pneumonia, Viral - virology | Antibodies, Neutralizing - blood | Antigens | Medical research | Immune response | Microbiology | Communicable diseases | Antibodies | Disease susceptibility | Epidemiology | Risk factors | Viral antibodies | Medicine, Experimental | Health aspects | Index Medicus
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42. Full Text Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cells
by Choi, Youn Soo and Yang, Jessica A and Crotty, Shane
Current opinion in immunology, ISSN 0952-7915, 2013, Volume 25, Issue 3, pp. 366 - 372
Allergy and Immunology | Animals | Signal Transduction | T-Lymphocytes, Helper-Inducer - immunology | Humans | Vaccines - immunology | Cell Differentiation | Proto-Oncogene Proteins c-bcl-6 - immunology | Cytokines - immunology | T cells | Index Medicus
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43. Full Text The Receptor Ly108 Functions as a SAP Adaptor-Dependent On-Off Switch for T Cell Help to B Cells and NKT Cell Development
by Kageyama, Robin and Cannons, Jennifer L and Zhao, Fang and Yusuf, Isharat and Lao, Christopher and Locci, Michela and Schwartzberg, Pamela L and Crotty, Shane
Immunity (Cambridge, Mass.), ISSN 1074-7613, 06/2012, Volume 36, Issue 6, pp. 986 - 1002
Life Sciences & Biomedicine | Immunology | Science & Technology | Phosphorylation | Germinal Center - immunology | Antigens, Ly - genetics | Inositol Polyphosphate 5-Phosphatases | CD4-Positive T-Lymphocytes - immunology | Intracellular Signaling Peptides and Proteins - deficiency | Lymphopoiesis - physiology | Phosphotyrosine - physiology | Antigens, Ly - physiology | Immunologic Deficiency Syndromes - immunology | Intracellular Signaling Peptides and Proteins - genetics | Mice, Inbred C57BL | Natural Killer T-Cells - cytology | Mice, Transgenic | Phosphoric Monoester Hydrolases - physiology | Amino Acid Motifs | Mice, Knockout | Animals | B-Lymphocytes - immunology | Signaling Lymphocytic Activation Molecule Associated Protein | Immunological Synapses - immunology | Immunologic Deficiency Syndromes - genetics | Mice | Protein Processing, Post-Translational | Intracellular Signaling Peptides and Proteins - physiology | Lymphocyte Cooperation - physiology | Computer software industry | T cells | Genetic disorders | Proteins | Confidence intervals | Biomedical research | Lymphocytes | Rodents | Viral infections | Immune system | Cell adhesion & migration | Index Medicus | Germinal centers | Lymphocytes B | SHP-1 protein | Cell adhesion | Immunity (humoral) | Immunological synapses | Lymphocytes T | Natural killer cells | Differentiation | adaptor proteins | SAP protein | CD4 antigen
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44. Full Text Harnessing CD4 + T cell responses in HIV vaccine development
by Streeck, Hendrik and D'souza, M Patricia and Littman, Dan R and Crotty, Shane
Nature medicine, ISSN 1078-8956, 02/2013, Volume 19, Issue 2, pp. 143 - 149
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | CD4-Positive T-Lymphocytes - immunology | HIV Antibodies - biosynthesis | Receptors, CXCR5 - analysis | Antibodies, Neutralizing - biosynthesis | Humans | AIDS Vaccines - immunology | Pathogens | Vaccines | Human immunodeficiency virus--HIV | Cells | Index Medicus
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45. Full Text Th1/Th17 polarization persists following whole-cell pertussis vaccination despite repeated acellular boosters
by Da Silva Antunes, Ricardo and Babor, Mariana and Carpenter, Chelsea and Khalil, Natalie and Cortese, Mario and Mentzer, Alexander J and Seumois, Grégory and Petro, Christopher D and Purcell, Lisa A and Vijayanand, Pandurangan and Crotty, Shane and Pulendran, Bali and Peters, Bjoern and Sette, Alessandro
The Journal of clinical investigation, ISSN 0021-9738, 08/2018, Volume 128, Issue 9, pp. 3853 - 3865
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Pertussis vaccines | Physiological aspects | Polarity (Biology) | Immune response | T cells | Health aspects | Memory (Computers) | Comparative analysis | Vaccination | Polarization | Helper cells | Infections | Lymphocytes T | Genomes | Vaccines | Pertussis | Interleukin 4 | Cell activation | Interleukin 5 | Granulocytes | Lymphocytes | Children | Interleukin 9 | Antigens | Immunological memory | Memory cells | Cytokines | Interleukin 13 | T cell receptors | Diphtheria | Interleukin 17 | CD4 antigen | Whooping cough | γ-Interferon | Tetanus | Index Medicus | Abridged Index Medicus
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46. Full Text Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation
by Kroenke, Mark A and Eto, Danelle and Locci, Michela and Cho, Michael and Davidson, Terence and Haddad, Elias K and Crotty, Shane
The Journal of immunology (1950), ISSN 0022-1767, 04/2012, Volume 188, Issue 8, pp. 3734 - 3744
Life Sciences & Biomedicine | Immunology | Science & Technology | Chemokines, CXC - immunology | Coculture Techniques | Germinal Center - immunology | Humans | DNA-Binding Proteins - metabolism | Interleukins - genetics | Transfection | T-Lymphocytes, Helper-Inducer - immunology | Inducible T-Cell Co-Stimulator Protein - genetics | T-Lymphocytes, Helper-Inducer - cytology | Transcription, Genetic | Cell Differentiation | Germinal Center - cytology | B-Lymphocytes - metabolism | Inducible T-Cell Co-Stimulator Protein - immunology | Proto-Oncogene Proteins c-maf - immunology | B-Lymphocytes - cytology | DNA-Binding Proteins - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Signal Transduction | Gene Expression Regulation - immunology | Proto-Oncogene Proteins c-maf - genetics | Cell Communication | Chemokines, CXC - genetics | DNA-Binding Proteins - genetics | Lentivirus | Protein Transport | Animals | B-Lymphocytes - immunology | Plasmids | Immunologic Memory | Proto-Oncogene Proteins c-maf - metabolism | Mice | Proto-Oncogene Proteins c-bcl-6 | Index Medicus | Abridged Index Medicus
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47. Full Text The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation
by Wang, Dapeng and Diao, Huitian and Getzler, Adam J and Rogal, Walter and Frederick, Megan A and Milner, Justin and Yu, Bingfei and Crotty, Shane and Goldrath, Ananda W and Pipkin, Matthew E
Immunity (Cambridge, Mass.), ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 659 - 674.e6
Runx-family transcription factor | epigenetic reprogramming | memory CTL differentiation | pioneer transcription factor | chromatin accessibility | Life Sciences & Biomedicine | Immunology | Science & Technology | T-Lymphocytes, Cytotoxic - immunology | Cell Line | Chromatin - metabolism | Core Binding Factor Alpha 3 Subunit - metabolism | Cricetinae | Cell Proliferation | Chlorocebus aethiops | Humans | Mice, Inbred C57BL | Male | Enzyme Activation - immunology | Mice, Knockout | Cell Differentiation - immunology | Animals | Binding Sites - immunology | Interferon Regulatory Factors - biosynthesis | Female | Receptors, Antigen, T-Cell - immunology | Mice | Positive Regulatory Domain I-Binding Factor 1 - biosynthesis | T-Lymphocytes, Cytotoxic - cytology | Vero Cells | Immunologic Memory - immunology | Epigenetic inheritance | Medical colleges | Chromatin | Microbiology | T cells | Resveratrol | Cell proliferation | Repressing | Antigens | Memory cells | Transcription factors | Accessibility | CD8 antigen | Genomics | Cell division | Effector cells | Cytotoxicity | Stimulation | Infections | Lymphocytes T | T cell receptors | Regulatory sequences | Gene expression | Experiments | T-cell receptor | Lymphocytes | Interferon regulatory factor 4 | Differentiation | Runx3 protein | Index Medicus
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