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61. Full Text Engineered immunogen binding to alum adjuvant enhances humoral immunity
by Moyer, Tyson J and Kato, Yu and Abraham, Wuhbet and Chang, Jason Y. H and Kulp, Daniel W and Watson, Nicki and Turner, Hannah L and Menis, Sergey and Abbott, Robert K and Bhiman, Jinal N and Melo, Mariane B and Simon, Hayley A and Herrera-De la Mata, Sara and Liang, Shu and Seumois, Gregory and Agarwal, Yash and Li, Na and Burton, Dennis R and Ward, Andrew B and Schief, William R and Crotty, Shane and Irvine, Darrell J
Nature medicine, ISSN 1078-8956, 03/2020, Volume 26, Issue 3, pp. 430 - 440
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Immunization | Adjuvants, Immunologic - pharmacology | Nanoparticles - chemistry | Peptides - chemistry | Endocytosis - drug effects | Mice, Inbred C57BL | Peptides - immunology | Antigens - metabolism | Lymph Nodes - immunology | Immunologic Memory - drug effects | Phosphoserine - metabolism | Epitopes - immunology | B-Lymphocytes - drug effects | Animals | B-Lymphocytes - immunology | Lymphocyte Activation - drug effects | Protein Engineering | Immunity, Humoral - drug effects | Lymph Nodes - drug effects | Aluminum Hydroxide - pharmacology | Antigen Presentation - drug effects | Mice, Inbred BALB C | Adjuvants, Pharmaceutic | Genetic aspects | Alum | Human immunogenetics | Health aspects | Testing | Binding | Antigen presentation | Antigens | Peptides | Aluminum | Antigen processing | Antibodies | Adjuvants | Vaccines | Adjuvanticity | Bioavailability | Epitopes | Immunity | Lymph nodes | Nanoparticles | Cell activation | Lymphocytes B | Neutralizing | Aluminum hydroxide | Immunity (humoral) | Phosphoserine | Index Medicus
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62. Full Text Resolution of a chronic viral infection after interleukin-10 receptor blockade
by Ejrnaes, Mette and Filippi, Christophe M and Martinic, Marianne M and Ling, Eleanor M and Togher, Lisa M and Crotty, Shane and Von Herrath, Matthias G
The Journal of experimental medicine, ISSN 0022-1007, 10/2006, Volume 203, Issue 11, pp. 2461 - 2472
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Lymphocytic choriomeningitis virus - immunology | Receptors, Interleukin-10 - biosynthesis | Interleukin-10 - deficiency | Immune Sera - administration & dosage | Mice, Inbred C57BL | Rats | Antibodies, Monoclonal - therapeutic use | Lymphocytic Choriomeningitis - therapy | Lymphocytic Choriomeningitis - immunology | Mice, Knockout | Lymphocytic Choriomeningitis - metabolism | Animals | Antibodies, Monoclonal - administration & dosage | Interleukin-10 - antagonists & inhibitors | Interleukin-10 - genetics | Receptors, Interleukin-10 - antagonists & inhibitors | Interleukin-10 - secretion | Mice | Mice, Inbred BALB C | Chronic Disease | Receptors, Interleukin-10 - immunology | Index Medicus
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63. Full Text SAP is required for generating long-term humoral immunity
by Ahmed, Rafi and Crotty, Shane and Kersh, Ellen N and Cannons, Jennifer and Schwartzberg, Pamela L
Nature (London), ISSN 0028-0836, 01/2003, Volume 421, Issue 6920, pp. 282 - 287
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Biological and medical sciences | Immunobiology | Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation | Carrier Proteins - physiology | Lymphocytic choriomeningitis virus - immunology | Antibody Formation - immunology | Mice, Inbred C57BL | Intracellular Signaling Peptides and Proteins | Male | Adoptive Transfer | Mice, Knockout | CD4-Positive T-Lymphocytes - immunology | Carrier Proteins - genetics | Animals | B-Lymphocytes - immunology | Flow Cytometry | Time Factors | Immunoglobulin G - immunology | Signaling Lymphocytic Activation Molecule Associated Protein | Mice | Antibody Formation - genetics | Immunologic Memory - genetics | Immunologic Memory - immunology | Plasma Cells - immunology | Cellular biology | Genetics | Immune system | Index Medicus
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64. Full Text In Vivo RNA Interference Screens Identify Regulators of Antiviral CD4+ and CD8+ T Cell Differentiation
by Chen, Runqiang and Bélanger, Simon and Frederick, Megan A and Li, Bin and Johnston, Robert J and Xiao, Nengming and Liu, Yun-Cai and Sharma, Sonia and Peters, Bjoern and Rao, Anjana and Crotty, Shane and Pipkin, Matthew E
Immunity (Cambridge, Mass.), ISSN 1074-7613, 08/2014, Volume 41, Issue 2, pp. 325 - 338
Life Sciences & Biomedicine | Immunology | Science & Technology | Lymphocytic choriomeningitis virus - immunology | Cyclin T - biosynthesis | Lymphocytic Choriomeningitis - immunology | Th1 Cells - immunology | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - genetics | Lymphocyte Activation - immunology | Transduction, Genetic - methods | Immunologic Memory - immunology | T-Lymphocytes, Cytotoxic - immunology | RNA Interference - immunology | Cyclin-Dependent Kinase 9 - genetics | Mice, Inbred C57BL | Cyclin T - genetics | Transcription Factors - genetics | T-Box Domain Proteins - genetics | Cell Differentiation - immunology | Animals | Cyclin-Dependent Kinase 9 - biosynthesis | Mice | MicroRNAs - genetics | RNA, Small Interfering | Receptors, Antigen, T-Cell - genetics | CD8-Positive T-Lymphocytes - immunology | Positive Regulatory Domain I-Binding Factor 1 | Studies | Antigens | Transcription factors | Lymphocytes | Rodents | Infections | Gene expression | Experiments | Viral infections | Index Medicus
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65. Full Text Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b
by Cho, Sunglim and Lee, Hyang-Mi and Yu, I-Shing and Choi, Youn Soo and Huang, Hsi-Yuan and Hashemifar, Somaye Sadat and Lin, Ling-Li and Chen, Mei-Chi and Afanasiev, Nikita D and Khan, Aly Azeem and Lin, Shu-Wha and Rudensky, Alexander Y and Crotty, Shane and Lu, Li-Fan
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2757 - 13
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Germinal Center - immunology | Autoimmunity - genetics | Germinal Center - drug effects | Autoantibodies - biosynthesis | T-Lymphocytes, Helper-Inducer - drug effects | Signal Transduction - immunology | Interleukin-4 - pharmacology | T-Lymphocytes, Helper-Inducer - immunology | Bone Marrow Cells - immunology | T-Lymphocytes, Helper-Inducer - cytology | Bone Marrow Cells - drug effects | CD40 Antigens - genetics | Cell Differentiation | Germinal Center - cytology | B-Lymphocytes - cytology | Bone Marrow Cells - cytology | Immunity, Humoral - genetics | Gene Expression Regulation | Mice, Transgenic | MicroRNAs - immunology | B-Lymphocytes - drug effects | Animals | B-Lymphocytes - immunology | Mice | MicroRNAs - genetics | Primary Cell Culture | Protein Isoforms - immunology | CD40 Antigens - immunology | Protein Isoforms - genetics | Regulations | Signal transduction | Autoantibodies | CD40 antigen | Lymphocytes B | Clonal deletion | Lymphocytes | Immunity (humoral) | Lymphocytes T | Immunity | Molecular chains | Index Medicus
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66. Full Text ICOS Receptor Instructs T Follicular Helper Cell versus Effector Cell Differentiation via Induction of the Transcriptional Repressor Bcl6
by Choi, Youn Soo and Kageyama, Robin and Eto, Danelle and Escobar, Tania C and Johnston, Robert J and Monticelli, Laurel and Lao, Christopher and Crotty, Shane
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2011, Volume 34, Issue 6, pp. 932 - 946
Inducible T-Cell Co-Stimulator Protein | DNA-Binding Proteins - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Antigens, Differentiation, T-Lymphocyte - immunology | Signal Transduction | Dendritic Cells - immunology | Germinal Center - immunology | Antigens, Differentiation, T-Lymphocyte - metabolism | DNA-Binding Proteins - genetics | Receptors, CXCR5 - immunology | Receptors, Interleukin-2 - immunology | Proteins - immunology | Animals | Proteins - metabolism | Inducible T-Cell Co-Stimulator Ligand | T-Lymphocytes, Helper-Inducer - immunology | Transcription, Genetic | Cell Differentiation | Mice | Proto-Oncogene Proteins c-bcl-6 | Virus diseases | Genetic aspects | Dendritic cells | T cells | Index Medicus
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67. Full Text Reinvigorating NIH Grant Peer Review
by Crotty, Shane and Blish, Catherine and Cadwell, Ken and Chi, Hongbo and Goldrath, Ananda and Green, Douglas and Kaech, Susan M and Krummel, Matthew and Pepper, Marion and Rothlin, Carla V and Wherry, E. John and Once-a-Year Pledge Supporters and Once-A-Year Pledge Supporters
Immunity (Cambridge, Mass.), ISSN 1074-7613, 01/2020, Volume 52, Issue 1, pp. 1 - 3
Life Sciences & Biomedicine | Immunology | Science & Technology | National Institutes of Health (U.S.) | Peer Review, Research | United States | Humans | Research Support as Topic | Leadership | Incentives | Biomedical research | Funding | Grants | Studies | Format | Reviews | Quality | Scientists | Peer review | Budgets | Research centers | Logistics | Index Medicus
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68. Full Text Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans
by Mateus, Jose and Grifoni, Alba and Tarke, Alison and Sidney, John and Ramirez, Sydney I and Dan, Jennifer M and Burger, Zoe C and Rawlings, Stephen A and Smith, Davey M and Phillips, Elizabeth and Mallal, Simon and Lammers, Marshall and Rubiro, Paul and Quiambao, Lorenzo and Sutherland, Aaron and Yu, Esther Dawen and Da Silva Antunes, Ricardo and Greenbaum, Jason and Frazier, April and Markmann, Alena J and Premkumar, Lakshmanane and De Silva, Aravinda and Peters, Bjoern and Crotty, Shane and Sette, Alessandro and Weiskopf, Daniela
Science (American Association for the Advancement of Science), ISSN 0036-8075, 10/2020, Volume 370, Issue 6512, pp. 89 - 94
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Epitope Mapping | Genome, Viral | Pandemics | Humans | Open Reading Frames | Epitopes, T-Lymphocyte - genetics | Coronavirus Infections - immunology | Pneumonia, Viral - immunology | Betacoronavirus - immunology | CD4-Positive T-Lymphocytes - immunology | COVID-19 | Cross Reactions | Sequence Homology | Blood Donors | SARS-CoV-2 | Immunologic Memory | Epitopes, T-Lymphocyte - immunology | Betacoronavirus - genetics | Immunological memory | Memory cells | Immune response | Cold | Severe acute respiratory syndrome | Viral diseases | Viruses | Homology | Common cold | Genomes | Lymphocytes T | Coronaviruses | Epitopes | CD4 antigen | Severe acute respiratory syndrome coronavirus 2 | Heterogeneity | Immunology | Reactivity | Lymphocytes | Respiratory diseases | Interrogation | Immune system | Index Medicus | Microbio
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69. Full Text Pre-existing immunity to SARS-CoV-2: the knowns and unknowns (vol 52, pg 891, 2020)
by Sette, Alessandro and Crotty, Shane
Nature reviews. Immunology, ISSN 1474-1733, 10/2020, Volume 20, Issue 10, pp. 644 - 644
Immunology | Life Sciences & Biomedicine | Science & Technology
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70. Full Text T cells control the generation of nanomolar-affinity anti-glycan antibodies
by Polonskaya, Zinaida and Deng, Shenglou and Sarkar, Anita and Kain, Lisa and Comellas-Aragones, Marta and McKay, Craig S and Kaczanowska, Katarzyna and Holt, Marie and McBride, Ryan and Palomo, Valle and Self, Kevin M and Taylor, Seth and Irimia, Adriana and Mehta, Sanjay R and Dan, Jennifer M and Brigger, Matthew and Crotty, Shane and Schoenberger, Stephen P and Paulson, James C and Wilson, Ian A and Savage, Paul B and Finn, M.G and Teyton, Luc and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
The Journal of clinical investigation, ISSN 0021-9738, 04/2017, Volume 127, Issue 4, pp. 1491 - 1504
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Immunoglobulin G - blood | Vaccine Potency | Humans | Vaccination | Crystallography, X-Ray | Male | Streptococcus pneumoniae - immunology | CD4-Positive T-Lymphocytes - immunology | Glycopeptides - immunology | Pneumococcal Infections - immunology | Adult | Female | Bacterial Proteins - immunology | Antibodies, Bacterial - blood | Child | Polysaccharides, Bacterial - chemistry | Amino Acid Sequence | Antibodies, Bacterial - chemistry | Mice, Inbred C57BL | Models, Molecular | Polysaccharides, Bacterial - immunology | Antibody Affinity | Mice, SCID | Mice, Knockout | Pneumococcal Vaccines - chemistry | Animals | B-Lymphocytes - immunology | Hybridomas | Pneumococcal Infections - prevention & control | Pneumococcal Vaccines - immunology | Protein Binding | Mice, Inbred NOD | Viral antibodies | Physiological aspects | Antibodies | Immune response | T cells | Health aspects | Carbohydrates | Immunoglobulins | T cell receptors | Vaccines | Streptococcus infections | Proteins | Studies | Infectious diseases | Immunology | Acquired immune deficiency syndrome--AIDS | Microscopy | Lymphocytes | Ligands | Binding sites | Index Medicus | Abridged Index Medicus
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