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Journal of Neurotrauma, ISSN 0897-7151, 12/2012, Volume 29, Issue 18, pp. 2761 - 2773
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 5366 - 12
Retinoic acid inducible gene-I (RIG-I) ensures immune surveillance of viral RNAs bearing a 5'-triphosphate (5'ppp) moiety. Mutations in RIG-I (C268F and E373A)... 
SINGLETON-MERTEN SYNDROME | DOUBLE-STRANDED-RNA | MAVS | RECOGNITION | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | HYDROGEN/DEUTERIUM EXCHANGE | SIGNAL-ACTIVATION | RECEPTORS | PROTEINS | NF-KAPPA-B | RNA Caps - immunology | DEAD Box Protein 58 - metabolism | Protein Binding - genetics | Immunity, Innate - genetics | Autoimmunity - genetics | RNA Caps - metabolism | Signal Transduction - immunology | Guanosine - chemistry | DEAD Box Protein 58 - genetics | RNA Caps - chemistry | RNA, Double-Stranded - metabolism | Gain of Function Mutation | RNA, Double-Stranded - chemistry | Guanosine - analogs & derivatives | Recombinant Proteins - metabolism | DEAD Box Protein 58 - chemistry | Mutagenesis, Site-Directed | Adenosine Triphosphatases - metabolism | Interferon-Induced Helicase, IFIH1 - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Signal Transduction - genetics | Guanosine - metabolism | Protein Binding - immunology | Interferon-Induced Helicase, IFIH1 - immunology | Deuterium Exchange Measurement - methods | Caspase Activation and Recruitment Domain - immunology | Guanosine - immunology | DEAD Box Protein 58 - immunology | Recombinant Proteins - immunology | RNA, Double-Stranded - immunology | RNA, Viral - immunology | Methylation | Mass Spectrometry - methods | Deuterium | Multiple sclerosis | Caspase | Event-related potentials | Immunosurveillance | Locks | Ribonucleic acid--RNA | Bearing | Domains | DNA helicase | Signaling | Proofreading | Mutation | Autoimmune diseases | ATP | Retinoic acid | Adenosine triphosphatase | Cards
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0153608
Repetitive mild traumatic brain injury (r-mTBI) results in neuropathological and biochemical consequences in the human visual system. Using a recently... 
RETINAL GANGLION-CELLS | HEAT-SHOCK PROTEINS | MICROTUBULE-ASSOCIATED PROTEINS | OPTIC-NERVE LESION | MULTIDISCIPLINARY SCIENCES | AXONAL-TRANSPORT | BASIC-PROTEIN | ALTERED EXPRESSION | CATHEPSIN-D | MYELIN-ASSOCIATED GLYCOPROTEIN | APOLIPOPROTEIN-E | Biomarkers - metabolism | Optic Nerve - pathology | Humans | Mice, Inbred C57BL | Brain Injuries - complications | Male | Proteome - analysis | Vision Disorders - pathology | Brain Injuries - physiopathology | Retinal Ganglion Cells - metabolism | Retinal Ganglion Cells - pathology | Animals | Nervous System Diseases - etiology | Nervous System Diseases - metabolism | Mice | Lipids - analysis | Chronic Disease | Vision Disorders - metabolism | Nervous System Diseases - pathology | Optic Nerve - metabolism | Vision Disorders - etiology | Brain | Complications and side effects | Prognosis | Physiological aspects | Research | Injuries | Visual perception | Immunohistochemistry | Multiple sclerosis | Traumatic brain injury | Target recognition | Lecithin | Neuropathology | Change detection | Retina | Lipids | Phospholipids | Biochemistry | Lysophosphatidylcholine | Proteins | Depolymerization | Visual system | Head injuries | Filaments | Demyelination | Apolipoprotein E | Microtubule-associated proteins | Microtubule-associated protein 1 | Nerves | Anesthesia | Neurofilaments | Cathepsin D | Species | Injury analysis | Phosphatidylethanolamine | Biochemical analysis | Optic nerve | Myelin | Heat shock proteins | Histology | Brn-3 protein | Metabolism | Retinal ganglion cells | Brain research | Concussion | Correlation analysis | Collagen | Laboratory animals | Dismantling | Heat shock
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0119579
Gulf War Illness (GWI) is a chronic multisymptom illness with a central nervous system component such as memory deficits, neurological, and musculoskeletal... 
ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | VETERANS | ADULT HIPPOCAMPAL NEUROGENESIS | DISTANCE TRANSIT | CHEMICAL WEAPONS FALLOUT | PYRIDOSTIGMINE BROMIDE | PERMETHRIN | MILD COGNITIVE IMPAIRMENT | NEONATAL-RATS | BRAIN | Permethrin - toxicity | Humans | Astrocytes - pathology | Cerebral Cortex - pathology | Male | Hippocampus - drug effects | Cerebral Cortex - metabolism | Persian Gulf Syndrome - metabolism | Cerebral Cortex - physiopathology | Synaptophysin - genetics | Time Factors | Gulf War | Persian Gulf Syndrome - physiopathology | Synaptophysin - antagonists & inhibitors | Cerebral Cortex - drug effects | Persian Gulf Syndrome - pathology | Disease Models, Animal | Synaptophysin - metabolism | Astrocytes - drug effects | Gene Expression | Mice, Inbred C57BL | Memory, Long-Term - drug effects | Memory, Short-Term - drug effects | Hippocampus - pathology | Cognition - drug effects | Hippocampus - metabolism | Animals | Pyridostigmine Bromide - toxicity | Persian Gulf Syndrome - chemically induced | Mice | Hippocampus - physiopathology | Astrocytes - metabolism | Brain | Pyridostigmine | Research | Analysis | Memory | Neurosciences | Permethrin | Veterans | Neuropathology | Change detection | Central nervous system | Cognitive ability | War | Neurogenesis | Learning | Illnesses | Etiology | Rodents | Long term memory | Military personnel | Persian Gulf War | Synaptophysin | Phenotypes | Gulf War syndrome | Pesticides | Exposure | Neurological diseases | Studies | Computer memory | Brain research | Gliosis | Hospitals | Pyridostigmine bromide | Laboratory animals | Hippocampus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0176634
Journal Article
Immunity, ISSN 1074-7613, 12/2017, Volume 47, Issue 6, pp. 1182 - 1196.e10
CD4+ T cells are tightly regulated by microbiota in the intestine, but whether intestinal T cells interface with host-derived metabolites is less clear. Here,... 
cholestyramine | MDR1 | bile acids | IBD | T cells | Th1 | ileitis | Th17 | Crohn’s disease | Crohn's disease | ACTIVATION | BACTERIA | INFLAMMATORY-BOWEL-DISEASE | CD4(+) | TRAFFICKING | MICE | MECHANISMS | MICROBIOTA | IMMUNOLOGY | MULTIDRUG-RESISTANCE | P-GLYCOPROTEIN | Crohn Disease - genetics | Ileum - pathology | Bile Acids and Salts - pharmacology | Oxidative Stress | Humans | Middle Aged | Immunity, Mucosal | Male | Homeodomain Proteins - immunology | CD4-Positive T-Lymphocytes - pathology | Ileum - immunology | ATP Binding Cassette Transporter, Subfamily B, Member 1 - immunology | Ileitis - pathology | CD4-Positive T-Lymphocytes - immunology | Biological Transport | Intestinal Mucosa - immunology | Adult | Female | Disease Models, Animal | Tetrahydroisoquinolines - pharmacology | Bile Acids and Salts - immunology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Homeostasis - immunology | Bile Acids and Salts - metabolism | Mice, Transgenic | ATP Binding Cassette Transporter, Subfamily B, Member 1 - deficiency | Crohn Disease - immunology | Homeodomain Proteins - genetics | ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics | Animals | Crohn Disease - pathology | Ileitis - immunology | Acridines - pharmacology | Ileitis - genetics | Mice | CD4-Positive T-Lymphocytes - drug effects | Intestinal Mucosa - pathology | Homeostasis | Bile acids | Gastrointestinal diseases | Oxidative stress | Ileitis | Liver | Mucosa | Effector cells | Reabsorption | Lymphocytes T | Ileum | Cells | CD4 antigen | MDR1 protein | Microbiota | Acids | Metabolites | Lymphocytes | Intestine | Emulsifying agents | Transporter | Bile
Journal Article