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Heart, ISSN 1355-6037, 06/2017, Volume 103, Issue Suppl 5, pp. A127 - A128
IntroductionMicrovascular endothelial cells (ECs) are surrounded and supported by mural cells called pericytes. Via paracrine signalling and gap junctions,... 
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 09/2016, Volume 68, Issue 11, p. 1253
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 09/2016, Volume 68, Issue 11, p. 1253
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 22, pp. 2593 - 2603
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A14915 - A14915
Global and endothelium-specific insulin resistance is associated with accelerated atherosclerosis and increased Nox2 NADPH oxidase derived superoxide. We... 
Journal Article
BMJ Open, ISSN 2044-6055, 07/2019, Volume 9, Issue 7, pp. e028613 - e028613
IntroductionPermanent artificial pacemaker implantation is a safe and effective treatment for bradycardia and is associated with extended longevity and... 
Journal Article
by Nelson, Christopher P and Goel, Anuj and Butterworth, Adam S and Kanoni, Stavroula and Webb, Tom R and Marouli, Eirini and Zeng, Lingyao and Ntalla, Ioanna and Lai, Florence Y and Hopewell, Jemma C and Giannakopoulou, Olga and Jiang, Tao and Hamby, Stephen E and Di Angelantonio, Emanuele and Assimes, Themistocles L and Bottinger, Erwin P and Chambers, John C and Clarke, Robert and Palmer, Colin N A and Cubbon, Richard M and Ellinor, Patrick and Ermel, Raili and Evangelou, Evangelos and Franks, Paul W and Grace, Christopher and Gu, Dongfeng and Hingorani, Aroon D and Howson, Joanna M M and Ingelsson, Erik and Kastrati, Adnan and Kessler, Thorsten and Kyriakou, Theodosios and Lehtimäki, Terho and Lu, Xiangfeng and Lu, Yingchang and März, Winfried and McPherson, Ruth and Metspalu, Andres and Pujades-Rodriguez, Mar and Ruusalepp, Arno and Schadt, Eric E and Schmidt, Amand F and Sweeting, Michael J and Zalloua, Pierre A and Alghalayini, Kamal and Keavney, Bernard D and Kooner, Jaspal S and Loos, Ruth J F and Patel, Riyaz S and Rutter, Martin K and Tomaszewski, Maciej and Tzoulaki, Ioanna and Zeggini, Eleftheria and Erdmann, Jeanette and Dedoussis, George and Björkegren, Johan L M and Schunkert, Heribert and Farrall, Martin and Danesh, John and Samani, Nilesh J and Watkins, Hugh and Deloukas, Panos and Uk Biobank CardioMetab and EPIC-CVD Consortium and CardiogramplusC4D and UK Biobank CardioMetabolic Consortium CHD working group and CARDIoGRAMplusC4D and The UK Biobank CardioMetabolic Consortium CHD working group and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1385 - 1391
Genome-wide association studies (GWAS) in coronary artery disease (CAD) had identified 66 loci at 'genome-wide significance' (P < 5 x 10(-8)) at the time of... 
RISK LOCI | PROFILES | METAANALYSIS | DATABASE | RARE | LOW-FREQUENCY | ANNOTATION | GENETICS & HEREDITY | ATHEROSCLEROSIS | GENETIC-VARIANTS | GENOME-WIDE ASSOCIATION | Genetic Association Studies - standards | Health Information Systems - statistics & numerical data | Genetic Predisposition to Disease - genetics | Meta-Analysis as Topic | Reproducibility of Results | Humans | Risk Factors | Genetic Loci - genetics | Genetic Association Studies - methods | Genotype | United Kingdom | Genome-Wide Association Study - statistics & numerical data | Phenotype | Genetic Association Studies - statistics & numerical data | Coronary Artery Disease - genetics | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Genome-Wide Association Study - standards | Health Information Systems - standards | Genetic aspects | Disease susceptibility | Research | Coronary heart disease | Risk factors | Coronary artery | Cardiovascular disease | Genomes | Angina | Gene expression | Metabolism | Angina pectoris | Coronary artery disease | Loci | Meta-analysis | Morphogenesis | Studies | Consortia | Nitric oxide | Coronary vessels | Atherosclerosis | Heritability | Lipid metabolism | Bioinformatics | Heart diseases | Index Medicus | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Circulation, ISSN 0009-7322, 11/2016, Volume 134, Issue Suppl_1 Suppl 1, pp. A14065 - A14065
IntroductionNonsustained ventricular tachycardia (NSVT) is frequently identified in patients with permanent pacemakers (PPMs), but its associated features,... 
Journal Article
Heart, ISSN 1355-6037, 10/2016, Volume 102, Issue Suppl 8, p. A7
RationaleInsulin resistance increases the risk of cardiovascular disease. Previous work from our department using mice haploinsufficient for either the IR... 
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 350 - 11
Journal Article
Journal Article
Heart, ISSN 1355-6037, 06/2014, Volume 100, Issue Suppl 3, pp. A118 - A119
Introduction Insulin resistance predisposes to cardiovascular disease (CVD) by inducing endothelial cell (EC) dysfunction and impairs the capacity for... 
Journal Article
BMJ: British Medical Journal, ISSN 0959-8138, 5/2009, Volume 338, Issue 7702, pp. 1064 - 1069
Chronic heart failure is common, affecting about 900,000 people in the UK and with a prevalence of about 6-10% in people aged over 65 years; despite modern... 
Heart | Defibrillators | Mortality | Implantable defibrillators | Hospital admissions | Electrocardiography | Death | Clinical Review | Bundle branch block | Cardiac resynchronization therapy | Artificial pacemakers | Heart failure | Therapy
Journal Article
Diabetes, ISSN 0012-1797, 08/2011, Volume 60, Issue 8, pp. 2169 - 2178
Journal Article
Circulation Research, ISSN 0009-7330, 12/2016, Volume 120, Issue 5, pp. 784 - 798
Journal Article