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1. Full Text Surgical Management of Enneking Stage 3 Aggressive Vertebral Hemangiomas With Neurological Deficit by One Stage Posterior Total En Bloc Spondylectomy: A Review of 23 Cases
by Ji, Xinran and Wang, Song and Oner, F Cumhur and Bird, Justin E and Lu, Ning
SPINE, ISSN 0362-2436, 08/2019, p. 1
STUDY DESIGN.Clinical Case Series OBJECTIVE.To describe the treatment of aggressive vertebral hemangiomas (VHs) with neurological deficit treated with total en... 
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2. Full Text The influence of spine surgeons' experience on the classification and intraobserver reliability of the novel AOSpine thoracolumbar spine injury classification system : an international study
by Sadiqi, Said and Oner, F. Cumhur and Dvorak, Marcel F and Aarabi, Bizhan and Schroeder, Gregory D and Vaccaro, Alexander R
Spine, ISSN 0362-2436, 2015, Volume 40, Issue 23, pp. E1250 - E1256
Study Design. International validation study. Objective. To investigate the influence of the spine surgeons' level of experience on the intraobserver... 
Surgeons' experience | Spine | Thoracolumbar | Fracture | Intraobserver reliability | Aospine thoracolumbar spine injury classification system | Journal Article | Validation study | Spine trauma | Clinical Neurology | Orthopedics and Sports Medicine | Spinal injury classification | Research Support, Non-U.S. Gov't | International reliability | POSTERIOR LIGAMENTOUS COMPLEX | intraobserver reliability | spine trauma | thoracolumbar | spine | validation study | REPRODUCIBILITY | CLINICAL NEUROLOGY | fracture | surgeons' experience | aospine thoracolumbar spine injury classification system | international reliability | INTEGRITY | spinal injury classification | FRACTURES | ORTHOPEDICS | Clinical Competence | Lumbar Vertebrae - injuries | Spinal Fractures - classification | Humans | Surgeons | Observer Variation | Thoracic Vertebrae - injuries
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3. Full Text Subjects with diffuse idiopathic skeletal hyperostosis have an increased burden of coronary artery disease: An evaluation in the COPDGene cohort
by Oudkerk, Sytse F and Mohamed Hoesein, Firdaus A.A and PThM Mali, Willem and Öner, F. Cumhur and Verlaan, Jorrit-Jan and de Jong, Pim A and Kinney, Gregory L and Hokanson, John and Lynch, David and Silverman, Edwin K and Budoff, Matthew J and Regan, Elizabeth A
Atherosclerosis, ISSN 0021-9150, 08/2019, Volume 287, pp. 24 - 29
Diffuse idiopathic skeletal hyperostosis (DISH) is a common incidental finding on medical imaging and often thought to be benign. Our objective was to... 
Agatson score | DISH | Coronary artery disease | Calciumscore | Atherosclerosis | CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | ETIDRONATE | COMPUTED-TOMOGRAPHY | FEATURES | PATHOGENESIS | INSULIN | CHEST | ECTOPIC MINERALIZATION | CALCIFICATION | PERIPHERAL VASCULAR DISEASE | Medical research | CT imaging | Lung diseases, Obstructive | Medicine, Experimental | Cardiology | Exostosis | Coronary heart disease | Risk factors | Medical imaging equipment
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4. Full Text Liposomal drug delivery in an in vitro 3D bone marrow model for multiple myeloma
by Braham, Maaike Vj and Deshantri, Anil K and Minnema, Monique C and Öner, F Cumhur and Schiffelers, Raymond M and Fens, Marcel Ham and Alblas, Jacqueline
Journal of Nanomedicine, ISSN 1176-9114, 2018, Volume 13, pp. 8105 - 8118
Purpose: Liposomal drug delivery can improve the therapeutic index of treatments for multiple myeloma. However, an appropriate 3D model for the in vitro... 
targeted delivery | multiple myeloma | tumor microenvironment | liposomes | Journal Article | drug sensitivity and resistance testing | Liposomes | Tumor microenvironment | Targeted delivery | Drug sensitivity and resistance testing | Multiple myeloma | MICROSPHERES | DOXORUBICIN | NICHE | NANOSCIENCE & NANOTECHNOLOGY | BORTEZOMIB | PATHOPHYSIOLOGY | STRATEGIES | PATHOGENESIS | NANOPARTICLES | ENDOTHELIAL-CELLS | SYSTEMS | PHARMACOLOGY & PHARMACY | Cell Proliferation | Liposomes - administration & dosage | Humans | Drug Delivery Systems | Antibiotics, Antineoplastic - administration & dosage | Multiple Myeloma - drug therapy | Multiple Myeloma - pathology | Models, Biological | Bone Marrow - pathology | Tumor Cells, Cultured | In Vitro Techniques | Bone Marrow - drug effects | Doxorubicin - administration & dosage | Drugs | Antigens | Medical research | Drug delivery systems | Anthracyclines | Vehicles | Chemotherapy | Analysis | Stem cells | Medicine, Experimental | Drug therapy | Health aspects | Integrins | Cancer | Cell culture | Peptides | Lipids | Drug resistance | Patients | Cancer therapies | Nanoparticles | Pore size | Polyethylene glycol | Bone marrow | Extracellular matrix | drug delivery
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5. Full Text To the editor
by Sadiqi, Said and Lehr, A. Mechteld and Jacobs, Wilco C.H and Post, Marcel W and Oner, F. Cumhur
Spine, ISSN 0362-2436, 03/2016, Volume 41, Issue 5, pp. E302 - E303
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6. Full Text The efficacy of intrawound vancomycin powder and povidone-iodine irrigation to prevent surgical site infections in complex instrumented spine surgery
by Lemans, Justin V.C and Öner, F. Cumhur and Wijdicks, Sebastiaan P.J and Ekkelenkamp, Miquel B and Vogely, H. Charles and Kruyt, Moyo C
The Spine Journal, ISSN 1529-9430, 10/2019, Volume 19, Issue 10, pp. 1648 - 1656
Surgical site infections (SSIs) are notorious complications in spinal surgery and cause substantial patient morbidity. Intraoperative decontamination of the... 
Prevention | Intra-wound | Povidone-iodine | Spine | Prophylaxis | Surgical site infection | Postoperative infection | Intrawound | Intra-site | Vancomycin | ORTHOPEDICS | CLINICAL NEUROLOGY | Povidone | Powders | Surgery | Analysis | Health aspects | Infection control
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7. Full Text TO THE EDITOR
by Sadiqi, Said and Lehr, A. Mechteld and Jacobs, Wilco C. H and Post, Marcel W and Oner, F. Cumhur
SPINE, ISSN 0362-2436, 03/2016, Volume 41, Issue 5, pp. E302 - E303
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8. Full Text Toward a Specific Outcome Instrument for Spinal Trauma: How to Measure Function and Health
by Sadiqi, Said and Lehr, A. Mechteld and Post, Marcel W and Vaccaro, Alexander R and Dvorak, Marcel F and Oner, F. Cumhur
SPINE, ISSN 0362-2436, 05/2015, Volume 40, Issue 10, pp. E578 - E586
Study Design. Validation study. Objective. To investigate the most valid, reliable, and comprehensible response scale for spinal trauma patients to compare... 
PSYCHOMETRIC PROPERTIES | INTENSITY SCALES | LOW-BACK-PAIN | disability | reliability | FUNCTIONAL-CAPACITY | health | questionnaire design | DISABILITY SCALE | fracture | patient preference | VISUAL ANALOG SCALE | POPULATION NORMS | outcome instrument | functioning | spinal trauma | VERBAL RATING-SCALES | validity | QUALITY-OF-LIFE | HEALTH-STATUS | Disability | Validity | Spinal trauma | Health | Questionnaire design | Fracture | Patient preference | Reliability | Outcome instrument | Functioning | Predictive Value of Tests | Reproducibility of Results | Humans | Middle Aged | Male | Psychometrics | Treatment Outcome | Spinal Injuries - physiopathology | Recovery of Function | Spinal Injuries - therapy | Discriminant Analysis | Injury Severity Score | Young Adult | Spinal Cord - physiology | Spinal Injuries - diagnosis | Aged, 80 and over | Adult | Female | Interviews as Topic | Surveys and Questionnaires | Aged | Health Status | Pain Measurement
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9. Full Text Osteoinduction by Ex Vivo Nonviral Bone Morphogenetic Protein Gene Delivery Is Independent of Cell Type
by Loozen, Loek D and Kruyt, Moyo C and Vandersteen, Angela and Kragten, Angela H.M and Croes, Michiel and Öner, F. Cumhur and Alblas, Jacqueline
Tissue Engineering Part A, ISSN 1937-3341, 10/2018, Volume 24, Issue 19-20, pp. 1423 - 1431
Ex vivo nonviral gene delivery of bone inductive factors has the potential to heal bone defects. Due to their inherent role in new bone formation, multipotent... 
Original Article | Bioengineering | Biomedical Engineering | plasmid DNA | BMP | nonviral gene delivery | bone regeneration | Biochemistry | ex vivo transfection | Biomaterials | Gene Transfer Techniques | Osseointegration | Gene Expression | Paracrine Communication | Humans | Rats, Inbred F344 | Stromal Cells - metabolism | Viruses - metabolism | Plasmids - metabolism | Animals | Cell Differentiation | Transgenes | Bone Morphogenetic Proteins - genetics | Mesenchymal Stem Cells - metabolism | Osteogenesis | Stromal Cells - cytology | Fibroblasts - metabolism | STEM-CELLS | DESIGN | MATERIALS SCIENCE, BIOMATERIALS | EFFICACY | SAFETY | ENGINEERING, BIOMEDICAL | THERAPY CLINICAL-TRIAL | BMP-2 | VECTOR | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Biotechnology | Adipose tissue | Bone morphogenetic protein 2 | Gene transfer | Paracrine signalling | Leukocytes (mononuclear) | Gene expression | Biological activity | Defects | Proteins | Bone histomorphometry | Bone growth | Transfection | Stromal cells | Stem cells | Bone marrow | Fibroblasts | Genetic engineering | Autocrine signalling
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10. Full Text Comparison of polyetheretherketone versus silicon nitride intervertebral spinal spacers in a caprine model
by Kersten, Roel F. M. R and Wu, Gang and Pouran, Behdad and van der Veen, Albert J and Weinans, Harrie H and de Gast, Arthur and Öner, F. Cumhur and van Gaalen, Steven M
Journal of Biomedical Materials Research - Part B Applied Biomaterials, ISSN 1552-4973, 04/2019, Volume 107, Issue 3, pp. 688 - 699
Polyetheretherketone (PEEK) is commonly used as a spinal spacer for intervertebral fusion surgery. Unfortunately, PEEK is bioinert and does not effectively... 
polyetheretherketone | silicon nitride | interbody cage | osseointegration | caprine animal model | MATERIALS SCIENCE, BIOMATERIALS | CAGE | POSTEROLATERAL FUSION | ENGINEERING, BIOMEDICAL | BONE INGROWTH | SURFACE CHARACTERISTICS | TISSUE | IN-VIVO MODEL | BIOMECHANICAL STABILITY | LUMBAR INTERBODY FUSION | STRUCTURAL ORTHOPEDIC IMPLANTS | PEEK | Osseointegration | Surgical implants | Stability | Transplants & implants | Goats | Silicon nitride | Bone healing | Spacers | Biomaterials | Organic chemistry | Bone growth | Null hypothesis | Biomedical materials | Bone implants | Surgery | Spacer | Arthrodesis | Silicon | Bone | Osteogenesis
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11. Full Text Orthopaedic management of Hurler's disease after hematopoietic stem cell transplantation: a systematic review
by Linden, Marleen H and Kruyt, Moyo C and Sakkers, Ralph J. B and Koning, Tom J and Öner, F. Cumhur and Castelein, René M
Journal of Inherited Metabolic Disease, ISSN 0141-8955, 06/2011, Volume 34, Issue 3, pp. 657 - 669
Objective The introduction of hematopoietic stem cell transplantation (HSCT) has significantly improved the life‐span of Hurler patients (mucopolysaccharidosis... 
CORD BLOOD TRANSPLANTATION | BONE-MARROW-TRANSPLANTATION | GROWTH | ENDOCRINOLOGY & METABOLISM | GENETICS & HEREDITY | STORAGE DISORDERS | HIP-DYSPLASIA | FOLLOW-UP | CARPAL-TUNNEL-SYNDROME | MUSCULOSKELETAL MANIFESTATIONS | MUCOPOLYSACCHARIDOSIS-I HURLER | CHILDREN | Motor Activity - physiology | Orthopedics - methods | Humans | Mucopolysaccharidosis I - physiopathology | Mucopolysaccharidosis I - therapy | Growth and Development - physiology | Treatment Outcome | Hematopoietic Stem Cell Transplantation - methods | Musculoskeletal Development - physiology | Mucopolysaccharidosis I - complications | Development and progression | Dysplasia | Transplantation | Pitchers (Baseball) | Hematopoietic stem cells | Stem cells
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12. Full Text Toward Developing a Specific Outcome Instrument for Spine Trauma: An Empirical Cross-sectional Multicenter ICF-Based Study by AOSpine Knowledge Forum Trauma
by Oner, F. Cumhur and Sadiqi, Said and Lehr, A. Mechteld and Aarabi, Bizhan and Dunn, Robert N and Dvorak, Marcel F and Fehlings, Michael G and Kandziora, Frank and Post, Marcel W and Rajasekaran, S and Vialle, Luiz and Vaccaro, Alexander R
SPINE, ISSN 0362-2436, 09/2015, Volume 40, Issue 17, pp. 1371 - 1379
Study Design. Empirical cross-sectional multicenter study. Objective. To identify the most commonly experienced problems by patients with traumatic spinal... 
DEMOGRAPHICS | spine trauma | INTERNATIONAL CLASSIFICATION | disability | empirical study | health | spine | ICF | fracture | outcome instrument | functioning | patient perspective | CORD-INJURY | EPIDEMIOLOGY | Disability Evaluation | Spinal Injuries - surgery | Pain - surgery | Cross-Sectional Studies | Outcome Assessment (Health Care) | Health Status Indicators | Humans | Middle Aged | Male | Activities of Daily Living | Young Adult | Spinal Injuries - immunology | Adolescent | Aged, 80 and over | Disabled Persons - rehabilitation | Adult | Female | Aged | Health Status
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13. Full Text A Human Hematopoietic Niche Model Supporting Hematopoietic Stem and Progenitor Cells In Vitro
by Braham, Maaike V. J and Yim, Amelie S. P. Li and Mateos, Jara Garcia and Minnema, Monique C and Dhert, Wouter J. A and Oner, F. Cumhur and Robin, Catherine and Alblas, Jacqueline
Advanced Healthcare Materials, ISSN 2192-2640, 05/2019, Volume 8, Issue 10, pp. e1801444 - n/a
Niches in the bone marrow regulate hematopoietic stem and progenitor cell (HSPC) fate and behavior through cell–cell interactions and soluble factor secretion.... 
perivascular niches | 3D in vitro models | bone marrow microenvironments | endosteal niches | hematopoietic stem cell maintenance | HOMEOSTASIS | CYTOKINES | HYDROGELS | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | BONE-MARROW NICHE | NANOSCIENCE & NANOTECHNOLOGY | PROLIFERATION | COCULTURE | MESENCHYMAL STROMAL CELLS | RECAPITULATION | 3D SCAFFOLDS | DIFFERENTIATION | Analysis | Hematopoietic stem cells | CD34 antigen | Hydrogels | Secretion | Crosstalk | Cell interactions | Progenitor cells | Endothelial cells | Hemopoiesis | Biomedical materials | Hematopoiesis | Stromal cells | CD38 antigen | Cells (biology) | Bone marrow | Clusters | Hypoxia | Biocompatibility | Surface markers | Viability | Three dimensional models | Niches
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14. Full Text The Influence of Spine Surgeons’ Experience on the Classification and Intraobserver Reliability of the Novel AOSpine Thoracolumbar Spine Injury Classification System
: An International Studys
by Sadiqi, Said and Oner, F. Cumhur and Dvorak, Marcel F and Aarabi, Bizhan and Schroeder, Gregory D and Vaccaro, Alexander R
SPINE, ISSN 0362-2436, 12/2015, Volume 40, Issue 23, pp. E1250 - E1256
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15. Full Text Complications After Percutaneous Pedicle Screw Fixation for the Treatment of Unstable Spinal Metastases
by Versteeg, Anne L and Verlaan, Jorrit-Jan and de Baat, Paul and Jiya, Timothy and Stadhouder, Agnita and Diekerhof, Carel H and van Solinge, Guido B and Oner, F. Cumhur
Annals of Surgical Oncology, ISSN 1068-9265, 07/2016, Volume 23, Issue 7, pp. 2343 - 2349
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16. Full Text AO spine injury classification system: a revision proposal for the thoracic and lumbar spine
by Reinhold, Maximilian and Audigé, Laurent and Schnake, Klaus John and Bellabarba, Carlo and Dai, Li-Yang and Oner, F Cumhur
European Spine Journal, ISSN 0940-6719, 10/2013, Volume 22, Issue 10, pp. 2184 - 2201
The AO Spine Classification Group was established to propose a revised AO spine injury classification system. This paper provides details on the rationale,... 
Accuracy | Surgical Orthopedics | Medicine & Public Health | Spinal injury classification | Thoracolumbar | Neurosurgery | Reliability | Consensus development | SEVERITY SCORE | COMPLEX | INTEGRITY | FRACTURES | ORTHOPEDICS | MORPHOLOGY | CLINICAL NEUROLOGY | Spinal Fractures - diagnosis | Reproducibility of Results | Lumbar Vertebrae - injuries | Spinal Fractures - classification | Humans | Intervertebral Disc Displacement - diagnosis | Intervertebral Disc Displacement - classification | Trauma Severity Indices | Consensus | Practice Guidelines as Topic | Thoracic Vertebrae - injuries | Original
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17. Full Text AOSpine subaxial cervical spine injury classification system
by Vaccaro, Alexander R and Koerner, John D and Radcliff, Kris E and Oner, F. Cumhur and Reinhold, Maximilian and Schnake, Klaus J and Kandziora, Frank and Fehlings, Michael G and Dvorak, Marcel F and Aarabi, Bizhan and Rajasekaran, Shanmuganathan and Schroeder, Gregory D and Kepler, Christopher K and Vialle, Luiz R
European Spine Journal, ISSN 0940-6719, 07/2016, Volume 25, Issue 7, pp. 2173 - 2184
Purpose: This project describes a morphology-based subaxial cervical spine traumatic injury classification system. Using the same approach as the thoracolumbar... 
Orthopedics and Sports Medicine | Spine | Injury | Surgery | Cervical | Classification | Subaxial | Trauma | Journal Article | AOSpine | Surgical Orthopedics | Medicine & Public Health | Neurosurgery | THORACOLUMBAR SPINE | COMPLEX | FACET DISLOCATION | VALIDATION | AGREEMENT | CLINICAL NEUROLOGY | COMPREHENSIVE CLASSIFICATION | ORTHOPEDICS | CORD INJURY | LONG-BONE FRACTURES | Reproducibility of Results | Cervical Vertebrae - diagnostic imaging | Cervical Vertebrae - injuries | Humans | Consensus | Spinal Fractures - diagnostic imaging | Neck Injuries - classification | Magnetic Resonance Imaging | Spinal Injuries - classification | Spinal Fractures - classification | Spinal Cord Injuries - classification | Spinal Cord Injuries - diagnostic imaging | Neck Injuries - diagnostic imaging | Spinal Injuries - diagnostic imaging
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18. Full Text Sustained Release of BMP-2 in Bioprinted Alginate for Osteogenicity in Mice and Rats
by Poldervaart, M.T and Wang, H and Stok, J. van der and Weinans, H and Leeuwenburgh, S.C.G and Oner, F.C and Dhert, W.J and Alblas, J
PLoS One, ISSN 1932-6203, 2013, Volume 8, Issue 8, p. e72610
The design of bioactive three-dimensional (3D) scaffolds is a major focus in bone tissue engineering. Incorporation of growth factors into bioprinted scaffolds... 
GELATIN | IN-VITRO | HYDROGELS | MICROSPHERES | VIVO | BONE MORPHOGENETIC PROTEIN-2 | REGENERATION | MULTIDISCIPLINARY SCIENCES | DIFFERENTIATION | SCAFFOLDS | DELIVERY | Goats | Rats, Wistar | Gelatin - pharmacology | Humans | Multipotent Stem Cells - metabolism | Tissue Scaffolds - chemistry | Microspheres | Multipotent Stem Cells - drug effects | Bone Morphogenetic Protein 2 - metabolism | Stromal Cells - drug effects | Female | Subcutaneous Tissue - metabolism | Alginates - pharmacology | Osteocalcin - metabolism | Osteogenesis - drug effects | Stromal Cells - metabolism | Hydroxyapatites - pharmacology | Glucuronic Acid - pharmacology | Animals | Bioprinting - methods | Cell Differentiation - drug effects | Mice, Nude | Multipotent Stem Cells - cytology | Delayed-Action Preparations | Stromal Cells - cytology | Hexuronic Acids - pharmacology | Bone morphogenetic proteins | Calcium phosphate | Comparative analysis | Product introduction | Tissue engineering | 3D printing | Phosphates | Biological properties | Surgical implants | Hydrogels | Calcium | Alginic acid | Microparticles | Vehicles | Proteins | Biomedical materials | Bone growth | Gelatin | Biocompatibility | Polymers | Growth factors | Drug dosages | Controlled release | Biodegradation | Printing | Bone morphogenetic protein 2 | Rats | Implantation | Biological activity | Calcium phosphates | Biomechanics | Three dimensional printing | Fractures | Stromal cells | Sustained release | Bone | Kinetics | Differentiation | Scaffolds | Osteogenesis
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19. Full Text AOSpine Knowledge Forums: Research in Motion
by Samartzis, D and Germscheid, N.M and Fehlings, M.G and Fisher, C.G and Kleuver, M. de and Oner, F.C and Yoon, S.T and Vialle, L.R
Global Spine Journal, ISSN 2192-5682, 2019, Volume 9, Issue 1_suppl, pp. 5s - 7s
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