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The New England Journal of Medicine, ISSN 0028-4793, 12/2014, Volume 371, Issue 24, pp. 2255 - 2266
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 485 - 485
Abstract Introduction Molecular mechanisms of multiple myeloma (MM) pathogenesis are unknown, but a role for bone marrow (BM) niche in supporting MM is well... 
Journal Article
Trends in Cell Biology, ISSN 0962-8924, 2012, Volume 22, Issue 4, pp. 201 - 210
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2014, Volume 371, Issue 24, pp. 2267 - 2276
This trial tested single versus dual inhibition of the renin–angiotensin–aldosterone system in ADPKD. ACE-inhibitor monotherapy controlled blood pressure in... 
RECEPTOR BLOCKER | MEDICINE, GENERAL & INTERNAL | RENIN | RAMIPRIL | COMBINATION THERAPY | ACE-INHIBITOR | BLOOD-PRESSURE CONTROL | PROTEINURIA | PROGRESSION | ALDOSTERONE SYSTEM | CONVERTING-ENZYME | Benzoates - therapeutic use | Renal Insufficiency, Chronic - etiology | Angiotensin II Type 1 Receptor Blockers - therapeutic use | Humans | Middle Aged | Hypertension - drug therapy | Male | Aldosterone - urine | Hypertension - etiology | Renal Insufficiency, Chronic - drug therapy | Young Adult | Glomerular Filtration Rate - drug effects | Lisinopril - therapeutic use | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Adult | Female | Blood Pressure - drug effects | Drug Therapy, Combination | Polycystic Kidney, Autosomal Dominant - drug therapy | Benzimidazoles - therapeutic use | Albuminuria - etiology | Double-Blind Method | Disease Progression | Kidney Failure, Chronic - prevention & control | Adolescent | Polycystic Kidney, Autosomal Dominant - physiopathology | Polycystic Kidney, Autosomal Dominant - complications | Treatment outcome | Care and treatment | Lisinopril | Analysis | Dosage and administration | Polycystic kidney disease | Telmisartan | Hypertension | End-stage renal disease | Excretion | Inhibitor drugs | Kidneys | Polycystic kidney | Diabetes mellitus | Albumin | Aldosterone | Glomerular filtration rate | Quality of life | Hyperkalemia | Renin | Pain | Angiotensin | Blood pressure | Kidney diseases | Drug therapy | Angiotensin II
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 11/2013, Volume 93, Issue 5, pp. 915 - 925
Intraflagellar transport (IFT) depends on two evolutionarily conserved modules, subcomplexes A (IFT-A) and B (IFT-B), to drive ciliary assembly and... 
VAN-CREVELD-SYNDROME | DYNC2H1 MUTATIONS | GENE | DISEASE | GENETICS & HEREDITY | CILIOPATHY | RIB-POLYDACTYLY SYNDROME | CILIA | KIDNEY | ASPHYXIATING THORACIC DYSTROPHY | INTRAFLAGELLAR TRANSPORT PROTEIN | Bone and Bones - pathology | Humans | Asian Continental Ancestry Group - genetics | Molecular Sequence Data | Male | Intracellular Signaling Peptides and Proteins - metabolism | Ellis-Van Creveld Syndrome - genetics | Ellis-Van Creveld Syndrome - pathology | Gene Knockdown Techniques | Bone and Bones - metabolism | Kidney Diseases, Cystic - genetics | Ectodermal Dysplasia - pathology | Female | Intracellular Signaling Peptides and Proteins - genetics | Cytoplasmic Dyneins - metabolism | Dyneins - metabolism | Amino Acid Sequence | European Continental Ancestry Group - genetics | Craniosynostoses - genetics | Cytoplasmic Dyneins - genetics | Retinitis Pigmentosa - genetics | Cerebellar Ataxia - pathology | Fibroblasts - pathology | Zebrafish - genetics | Kidney Diseases, Cystic - pathology | Phenotype | Animals | Cerebellar Ataxia - genetics | Epistasis, Genetic | Alleles | Ectodermal Dysplasia - genetics | Dyneins - genetics | Mutation | Bone and Bones - abnormalities | Retinitis Pigmentosa - pathology | Craniosynostoses - pathology | Physiological aspects | Ciliata | Genetic aspects | Research | Gene expression | Biological transport, Active | Report
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 05/2013, Volume 22, Issue 10, pp. 2024 - 2040
Journal Article
Nature Communications, ISSN 2041-1723, 01/2015, Volume 6, Issue 1, p. 6023
The ciliary kinase NEK8 plays a critical role in situs determination and cystic kidney disease, yet its exact function remains unknown. In this study, we... 
CILIARY | LOCALIZATION | TRANSITION ZONE | POLYCYSTIC KIDNEY-DISEASE | MULTIDISCIPLINARY SCIENCES | MOUSE | NEPHRONOPHTHISIS | LEFT-RIGHT ASYMMETRY | MUTATIONS | CONGENITAL HEART-DEFECTS | INVERSUS
Journal Article
Journal Article