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PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 7, p. e11469
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2009, Volume 4, Issue 6, p. e5994
Background: The immunosuppressive drug rapamycin (RAPA) promotes the expansion of CD4(+) CD25(high)Foxp3(+) regulatory T cells via mechanisms that remain... 
BIOLOGY | Interleukin-2 - metabolism | T-Lymphocytes, Regulatory - metabolism | Cell Proliferation | Antibiotics, Antineoplastic - pharmacology | Signal Transduction | Cross-Linking Reagents - pharmacology | Humans | CD4-Positive T-Lymphocytes - metabolism | Interleukin-2 Receptor alpha Subunit - biosynthesis | Interleukin Receptor Common gamma Subunit - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Sirolimus - pharmacology | CD3 Complex - biosynthesis | T-Lymphocytes, Regulatory - drug effects | CD28 Antigens - biosynthesis | Leukocytes, Mononuclear - cytology | CD4-Positive T-Lymphocytes - drug effects | Apoptosis | Proteins | Rapamycin | T cells | Protein binding | TOR protein | Cell proliferation | Cell culture | Transplants & implants | CD8 antigen | Antibodies | Homeostasis | Effector cells | Lymphocytes T | CD28 antigen | Immunosuppressive agents | T-cell receptor | Signal transduction | Cell activation | Pathways | Interleukin 2 | Lymphocytes | Immunotherapy | Peripheral blood mononuclear cells | CD25 antigen | Expansion | Interleukin 2 receptors | Antigens | Cytokines | Immunoregulation | Stat3 protein | Cultures | CD3 antigen | T cell receptors | Stat5 protein | Survival | 1-Phosphatidylinositol 3-kinase | CD4 antigen | Medicine | Pathology | Signaling | Protein expression | Regulation | Annexin V | Autoimmune diseases | Human behavior | PTEN protein | Cancer
Journal Article
Cancer Research, ISSN 0008-5472, 04/2009, Volume 69, Issue 7, pp. 3105 - 3113
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 07/2019, Volume 10, Issue 1, pp. 3000 - 16
Tumor-driven immune suppression is a major barrier to successful immunotherapy in ovarian carcinomas (OvCa). Among various mechanisms responsible for immune... 
APOPTOSIS | MICROENVIRONMENT | IMMUNOTHERAPY | IMMUNOSUPPRESSION | MULTIDISCIPLINARY SCIENCES | L-ARGININE | EXOSOMES | CANCER | EXPRESSION | CHEMOTHERAPY | LYMPHOCYTES | Cell proliferation | Antigens | Animal models | Ovarian carcinoma | Dendritic cells | Tumor cells | CD8 antigen | Arginase | Lymphocytes T | Lymph nodes | CD4 antigen | Drainage | Vesicles | Immunotherapy | Electric vehicles | Ascites | Tumors | Immune system
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 3975 - 3975
Journal Article
OncoImmunology, ISSN 2162-402X, 11/2019, Volume 8, Issue 11, p. e1655370
Expression of arginase-1 (ARG1) is an immunosuppressive feature of tumor microenvironment that leads to depletion of ʟ-arginine, a nutrient required for... 
ovarian carcinoma | Arginase | extracellular vesicles | T-cells response | immunotherapy | ONCOLOGY | IMMUNOLOGY
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 3/2012, Volume 61, Issue 3, pp. 373 - 384
Peptide antigens have been administered by different approaches as cancer vaccine therapy, including direct injection or pulsed onto dendritic cells; however,... 
Cancer vaccine | Immunology | Medicine & Public Health | Oncology | Cancer Research | IL-2 | p53 | Ovarian cancer | ADVANCED BREAST-CANCER | COLONY-STIMULATING FACTOR | CTL RESPONSES | ANTIGEN PRESENTATION | MELANOMA PATIENTS | IMMUNOLOGY | INTRANODAL INJECTION | IMMUNIZATION | METASTATIC RENAL-CANCER | ONCOLOGY | ANTITUMOR IMMUNE-RESPONSES | REGULATORY T-CELLS | Injections, Intravenous | Interleukin-2 - adverse effects | Dendritic Cells - immunology | Humans | Middle Aged | Ovarian Neoplasms - pathology | Fatigue - etiology | Vaccination - adverse effects | Lymphopenia - etiology | Interleukin-2 - immunology | Vaccination - methods | T-Lymphocytes - metabolism | Interleukin-2 - administration & dosage | T-Lymphocytes - drug effects | Injections, Subcutaneous | Adult | Female | Vaccines, Subunit - adverse effects | Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage | HLA-A2 Antigen - immunology | Cancer Vaccines - administration & dosage | Risk Factors | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Cancer Vaccines - adverse effects | Treatment Outcome | Combined Modality Therapy | Tumor Suppressor Protein p53 - immunology | Vaccines, Subunit - immunology | Cancer Vaccines - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Vaccines, Subunit - administration & dosage | Ovarian Neoplasms - therapy | T-Lymphocytes - immunology | Aged | Dendritic Cells - transplantation | Cohort Studies | Ovarian Neoplasms - immunology | Antigens | Care and treatment | Online health care information services | Peptides | Dendritic cells | Vaccination | HLA histocompatibility antigens | Clinical trials | Vaccines | Information management | Risk factors | Biometry | Cancer vaccines | Histocompatibility antigens | Interleukins | Immunotherapy | Product development | Universities and colleges | Tumor proteins | Health aspects | Cancer | Index Medicus | Immune response | Intravenous administration | Granulocyte-macrophage colony-stimulating factor | Immunoregulation | Toxicity | Adjuvants | Lymphocytes T | p53 protein | Side effects | Interleukin 2 | Histocompatibility antigen HLA | Enzyme-linked immunosorbent assay
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Extracellular Vesicles, 01/2018, Volume 7, pp. 51 - 52
Background: We have shown previously that exosomes derived from ascites of patients with ovarian cancer (OvCa) and from OvCa cell lines (TEX) contain... 
Cell proliferation | Cell culture | Ovarian carcinoma | CD8 antigen | Arginase | Ultracentrifugation | Lymphocytes T | Exosomes | Adoptive transfer | Western blotting | Ovarian cancer | CD69 antigen | Lymphocytes | Bone marrow | Antigens | Dendritic cells | T cell receptors | CD3 antigen | CD4 antigen | Immunosuppression | Antigen-presenting cells | Medical prognosis | Cell lines | Ascites | Peritoneum | Tumors
Journal Article
Oncogene, ISSN 0950-9232, 12/2009, Volume 28, Issue 49, pp. 4353 - 4363
Toll-like receptors (TLRs) expressed on immune cells trigger inflammatory responses. TLRs are also expressed on ovarian cancer (OvCa) cells, but the... 
paclitaxel | ovarian cancer | TLR4 | MyD88
Journal Article
Blood, ISSN 0006-4971, 11/2009, Volume 114, Issue 22, pp. 2678 - 2678
Abstract Abstract 2678 Poster Board II-654 Natural killer (NK) cell cytotoxicity in patients with acute myeloid leukemia (AML) is significantly decreased... 
Journal Article
Blood, ISSN 0006-4971, 11/2007, Volume 110, Issue 11, pp. 2835 - 2835
Abstract Regulatory CD4+CD25+ T cells (T reg) are critical regulators of immune tolerance. Increasing evidence supports the existence of elevated numbers of... 
Journal Article