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1. Full Text Sepsis: From Pathophysiology to Individualized Patient Care
by László, Ildikó and Trásy, Domonkos and Molnár, Zsolt and Fazakas, János
Journal of Immunology Research, ISSN 2314-8861, 2015, Volume 2015, pp. 510436 - 13
Sepsis has become a major health economic issue, with more patients dying in hospitals due to sepsis related complications compared to breast and colorectal... 
C-REACTIVE PROTEIN | MICROCIRCULATORY DYSFUNCTION | PROCALCITONIN LEVELS | POLYMERASE-CHAIN-REACTION | ANTI-PD-1 ANTIBODY | SEPTIC SHOCK | INVASIVE FUNGAL-INFECTIONS | IMMUNOLOGY | INFLAMMATORY RESPONSE | CRITICALLY-ILL PATIENTS | MESENCHYMAL STEM-CELLS | Patient Care | Calcitonin - blood | Sepsis - etiology | Protein Precursors - blood | Humans | Sepsis - therapy | Sepsis - epidemiology | Biomarkers | Sepsis - diagnosis | Disease Management | Calcitonin - metabolism | Protein Precursors - metabolism | Studies | Medicine | Intensive care | Hospitals | Immunology | Disease | Mortality | Clinical trials | Sepsis | Hospitalization | Family medical history | Epidemiology | Review
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2. Full Text Extracorporeal cytokine adsorption in septic shock: A proof of concept randomized, controlled pilot study
by Hawchar, Fatime and László, Ildikó and Öveges, Nándor and Trásy, Domonkos and Ondrik, Zoltán and Molnar, Zsolt
Journal of Critical Care, ISSN 0883-9441, 02/2019, Volume 49, pp. 172 - 178
The aim of this proof of concept, prospective, randomized pilot trial was to investigate the effects of extracorporeal cytokine removal (CytoSorb®) applied as... 
Septic shock | Hemoadsorption | CytoSorb | Cytokine removal | Cytokine storm | Extracorporeal blood purification | MANAGEMENT | BLOOD PURIFICATION | PROCALCITONIN | INTENSIVE-CARE | REMOVAL | THERAPY | COSTS | SEVERE SEPSIS | CRITICAL CARE MEDICINE | Clinical trials | Endothelin | C-reactive protein | Cytokines | Adsorption
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3. Full Text Goal-Directed Resuscitation Aiming Cardiac Index Masks Residual Hypovolemia: An Animal Experiment
by Tánczos, Krisztián and Tánczos, Krisztián and Németh, Márton and Németh, Márton and Trásy, Domonkos and Trásy, Domonkos and László, Ildikó and László, Ildikó and Palágyi, Péter and Palágyi, Péter and Szabó, Zsolt and Szabó, Zsolt and Varga, Gabriella and Varga, Gabriella and Kaszaki, József and Kaszaki, József
BioMed Research International, ISSN 2314-6133, 2015, Volume 2015, pp. 160979 - 8
The aim of this study was to compare stroke volume (SVI) to cardiac index (CI) guided resuscitation in a bleeding-resuscitation experiment. Twenty six pigs... 
HEMORRHAGIC-SHOCK | MEDICINE, RESEARCH & EXPERIMENTAL | CONTROLLED-TRIAL | THERAPY | VENOUS OXYGEN-SATURATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CIRCULATORY SHOCK | FLUID RESPONSIVENESS | OF-THE-LITERATURE | RISK SURGICAL-PATIENTS | INTENSIVE-CARE | SEVERE SEPSIS | Resuscitation - methods | Blood Gas Analysis | Hypovolemia - physiopathology | Stroke Volume - physiology | Random Allocation | Tachycardia - etiology | Hemorrhage | Animals | Isotonic Solutions - chemistry | Fluid Therapy - methods | Swine | Oxygen - chemistry | Shock - therapy | Hemodynamics | Hypovolemia - therapy | Resuscitation | Methods
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4. Full Text Developments in water quality monitoring and management in large river catchments using the Danube River as an example
by Chapman, Deborah V and Bradley, Chris and Gettel, Gretchen M and Hatvani, István Gábor and Hein, Thomas and Kovács, József and Liska, Igor and Oliver, David M and Tanos, Péter and Trásy, Balázs and Várbíró, Gábor
Environmental Science and Policy, ISSN 1462-9011, 10/2016, Volume 64, pp. 141 - 154
Effective management of water quality in large rivers requires information on the influence of activities within the catchment (urban and rural) throughout the... 
Transboundary rivers | Monitoring networks | International river basins | Water quality monitoring | Danube River Basin | EUROPEAN RIVER | COMBINED CLUSTER | PHARMACEUTICALS | URBAN STREAMS | SEDIMENTS | ESCHERICHIA-COLI | CLASSIFICATION | ENVIRONMENTAL SCIENCES | COMMON IMPLEMENTATION STRATEGY | SAMPLING FREQUENCY | LAND-USE | Water | Management | Research institutes | Ecosystems | Water quality | Quality control | Usage | Wastewater
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5. Full Text Delta Procalcitonin Is a Better Indicator of Infection Than Absolute Procalcitonin Values in Critically Ill Patients: A Prospective Observational Study
by Trásy, Domonkos and Trásy, Domonkos and Tánczos, Krisztián and Tánczos, Krisztián and Németh, Márton and Németh, Márton and Hankovszky, Péter and Hankovszky, Péter and Lovas, András and Lovas, András and Mikor, András and Mikor, András and Hajdú, Edit and Hajdú, Edit and Osztroluczki, Angelika and Osztroluczki, Angelika and Fazakas, János and Fazakas, János and Molnár, Zsolt and Molnár, Zsolt
Journal of Immunology Research, ISSN 2314-8861, 2016, Volume 2016, pp. 3530752 - 9
Purpose. To investigate whether absolute value of procalcitonin (PCT) or the change (delta-PCT) is better indicator of infection in intensive care patients.... 
C-REACTIVE PROTEIN | ADULTS | SURVIVING SEPSIS CAMPAIGN | IMMUNOLOGY | PROGNOSTIC VALUE | Calcitonin - blood | Prognosis | Prospective Studies | C-Reactive Protein | Humans | Middle Aged | Critical Illness | Infection - blood | Infection - mortality | Male | Infection - etiology | Infection - diagnosis | Protein Isoforms | Sensitivity and Specificity | Aged, 80 and over | Biomarkers | Adult | Female | ROC Curve | Aged | Leukocyte Count | Medicine | Intensive care | Bacterial infections | Antibiotics | Surgery | Body temperature | Mortality | Infections | Patients
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6. Full Text Early procalcitonin kinetics and appropriateness of empirical antimicrobial therapy in critically ill patients. A prospective observational study
by Trásy, Domonkos and Tánczos, Krisztián and Németh, Márton and Hankovszky, Péter and Lovas, András and Mikor, András and László, Ildikó and Hajdú, Edit and Osztroluczki, Angelika and Fazakas, János and Molnár, Zsolt and EProk Study Grp and EProK study group
Journal of Critical Care, ISSN 0883-9441, 08/2016, Volume 34, pp. 50 - 55
Purpose: The purpose was to investigate the value of procalcitonin (PCT) kinetics in predicting the appropriateness of empirical antimicrobial treatment in... 
Infection | Biomarkers | Sepsis | Appropriate antimicrobial therapy | Procalcitonin | Empirical antimicrobial therapy | C-REACTIVE PROTEIN | DIAGNOSTIC-VALUE | ANTIBIOTICS | MANAGEMENT | GUIDELINES | INTENSIVE-CARE UNITS | MARKERS | SURVIVING SEPSIS CAMPAIGN | SEPTIC SHOCK | INFECTIOUS-DISEASES SOCIETY | CRITICAL CARE MEDICINE | Calcitonin - drug effects | Calcitonin - blood | Prospective Studies | Hospital Mortality | Protein Precursors - blood | Anti-Infective Agents - pharmacology | Humans | Anti-Infective Agents - therapeutic use | Male | Anti-Infective Agents - administration & dosage | Critical Illness - therapy | Female | ROC Curve | Aged
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7. Full Text Continuous central venous oxygen saturation assisted intraoperative hemodynamic management during major abdominal surgery: A randomized, controlled trial
by Mikor, András and Trásy, Domonkos and Németh, Márton F and Osztroluczki, Angelika and Kocsi, Szilvia and Kovács, Ildikó and Demeter, Gábor and Molnár, Zsolt
BMC Anesthesiology, ISSN 1471-2253, 06/2015, Volume 15, Issue 1, p. 82
Background: Major abdominal surgery is associated with significant risk of morbidity and mortality in the perioperative period. Optimising intraoperative fluid... 
Haemodynamic management | Central venous oxygen saturation | Postoperative complications | PREDICT FLUID RESPONSIVENESS | SURGICAL-PATIENTS | MULTICENTER | HOSPITAL STAY | STRATEGY | PULSE PRESSURE VARIATION | RESTRICTION | GOAL | THERAPY | ANESTHESIOLOGY | Blood Loss, Surgical - statistics & numerical data | Humans | Middle Aged | Isotonic Solutions - administration & dosage | Venous Pressure - physiology | Male | Survival Rate | Postoperative Complications - epidemiology | Arterial Pressure - physiology | Blood Transfusion - statistics & numerical data | Hemodynamics - physiology | Abdomen - surgery | Oxygen - blood | Fluid Therapy - methods | Intraoperative Care - methods | Female | Aged | Blood transfusion
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8. Full Text Continuous central venous oxygen saturation assisted intraoperative hemodynamic management during major abdominal surgery improves outcome
: 4AP4-6
by Trásy, D and Mikor, A and Németh, M. F and Kovács, I and Demeter, G and Molnár, Z
European Journal of Anaesthesiology, ISSN 0265-0215, 06/2014, Volume 31, pp. 62 - 63
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9. Full Text Effects of goal-directed crystalloid vs. colloid fluid therapy on microcirculation during free flap surgery: A randomised clinical trial
by László, Ildikó and Janovszky, Ágnes and Lovas, András and Vargán, Viktória and Öveges, Nándor and Tánczos, Tamás and Mikor, András and Trásy, Domonkos and Lóderer, Zoltán and Piffkó, József and Szabó, Andrea and Molnár, Zsolt
European Journal of Anaesthesiology, ISSN 0265-0215, 08/2019, Volume 36, Issue 8, pp. 592 - 604
BACKGROUNDMacro, and microcirculatory effects of crystalloids and colloids are difficult to compare, because interventions to achieve haemodynamic stability... 
SHOCK | HYDROXYETHYL STARCH | ANESTHESIOLOGY | PRINCIPLE | ALBUMIN | SEPSIS | SALINE | INTENSIVE-CARE | RESUSCITATION | Microcirculation | Colloids in medicine | Usage | Surgery, Plastic | Electrolyte solutions | Hemodynamic monitoring | Fluid therapy | Comparative analysis | Health aspects | Methods
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10. Full Text ESICM LIVES 2016: part one
by L Bos and L Schouten and L van Vught and M Wiewel and D Ong and O Cremer and A Artigas and I Martin-Loeches and A Hoogendijk and T van der Poll and J Horn and N Juffermans and M Schultz and N de Prost and T Pham and G Carteaux and A Mekontso Dessap and C Brun-Buisson and E Fan and G Bellani and J Laffey and A Mercat and L Brochard and B Maitre and P A Howells and D R Thickett and C Knox and D P Park and F Gao and O Tucker and T Whitehouse and D F McAuley and G D Perkins and L Pisani and J P Roozeman and F D Simonis and A Giangregorio and L R Schouten and S M Van der Hoeven and A Serpa Neto and E Festic and A M Dondorp and S Grasso and L D Bos and M J Schultz and M Koster-Brouwer and D Verboom and B Scicluna and K van de Groep and J Frencken and M Bonten and J I Ko and K S Kim and G J Suh and W Y Kwon and K Kim and J H Shin and O T Ranzani and E Prina and R Menendez and A Ceccato and R Mendez and C Cilloniz and A Gabarrus and M Ferrer and A Torres and A Urbano and L A Zhang and D Swigon and F Pike and R S Parker and G Clermont and C Scheer and S O Kuhn and A Modler and M Vollmer and C Fuchs and K Hahnenkamp and S Rehberg and M Gründling and A Taggu and N Darang and N Öveges and I László and K Tánczos and M Németh and G Lebák and B Tudor and D Érces and J Kaszaki and W Huber and D Trásy and Z Molnár and G Ferrara and V S Kanoore Edul and H S Canales and E Martins and C Canullán and G Murias and M O Pozo and ...
Intensive Care Medicine Experimental, 09/2016, Volume 4, Issue 1, pp. 1 - 203
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11. Full Text ESICM LIVES 2016: part one : Milan, Italy. 1-5 October 2016
by Pizzaballa, M.L and Doronzio, A and Balicco, B and Kiers, H.D and Heijden, W.A. van der and Gerretsen, J and Mast, Q. de and El Messaoudi, S and Rongen, G.A and Gomes, M.E and Kox, M and Pickkers, P and Riksen, N.P and Kashiwagi, Y and Okada, M and Hayashi, K and Inagaki, Y and Fujita, S and Nakamae, M.N and Kang, Y.R and Souza, R.B and Liberatore, A.M and Koh, I.H and Blet, A and Sadoune, M and ARIAM-CARDIAC SURGERY PROJECT AUTHORS and Mid-Norway Sepsis Research Center and LUNG SAFE Investigators and the ESICM Trials Group and ECOCRITIC group and FINNAKI Study Group and for the Xe-HYPOTHECA study group and The Korean Chungcheong Critical Care Research Group and H1N1 SEMICYUC/GETGAG Working Group and NEFROCON Investigators and P-INFECT and KARISMA and LUNG SAFE investigators and the ESICM study group and ARIAM-SEMICYUC Registry Investigators and SICM NICER Group and for the GRAVITY-VAP TRIAL NETWORK and United States Critical Illness and Injury Trials Group/LIPS-B investigators and SIRAKI group and ARIAM Group and Apelin Group and for the Section on Ethics of the ESICM and EXODUS-investigators and The RAPIT Group and CAPCRI Study and Cardiac Arrest Group HUVR and Clinical Intensive Care Research Basel
Intensive Care Medicine Experimental, ISSN 2197-425X, 2016, Volume 4, Issue S1, pp. 27 - 27
Medicine & Public Health | Intensive / Critical Care Medicine
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12. Full Text Effect of lung recruitment on oxygenation in patients with acute lung injury ventilated in CPAP/pressure support mode
by Lovas, A and Trasy, D and Nemeth, M and Laszlo, I and Molnar, Z
Critical Care, ISSN 1364-8535, 2015, Volume 19, Issue Suppl 1, pp. P226 - P226
One of the aims of lung recruitment is to improve oxygenation [1], but it has not yet been investigated in spontaneously breathing patients. Our objective was... 
Respiratory therapy | Recruitment | Poster Presentation
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13. Full Text Which Patients Would Benefit From Antibiotic Prophylaxis: A "Burning" Question?
by Hankovszky, P and Trasy, D and Molnar, Z
CLINICAL INFECTIOUS DISEASES, ISSN 1058-4838, 01/2016, Volume 62, Issue 1, pp. 67 - 68
CONTROLLED-TRIALS | INFECTIOUS DISEASES | MANAGEMENT | mechanical ventilation | mortality | MICROBIOLOGY | IMMUNOLOGY | antibiotics | INTENSIVE-CARE | burns
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14. Full Text FiO2/PEEP index: a simple tool for opitimizing ventilator settings
by Trasy, D and Nemeth, M and Kiss, K and Till, Z and Molnar, Z
Critical Care, ISSN 1364-8535, 2013, Volume 17, Issue Suppl 2, pp. P90 - P90
Poster Presentation
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15. Full Text Preconditioning with volatile anaesthetic sevoflurane in ischemic retinal lesion in rats
by Szabadfi, Krisztina and Danyadi, Bese and Kiss, Peter and Manavalan, Sridharan and Gabriel, Robert and Reglodi, Dora and Tamas, Andrea and Trasy, Domonkos and Batai, Istvan
Journal of Molecular Histology, ISSN 1567-2379, 10/2012, Volume 43, Issue 5, pp. 565 - 569
Volatile anaesthetic agents have been recognized for their neuroprotective properties since the 1960s. However, little is known regarding the potential... 
Life Sciences | Ischemia | Sevoflurane preconditioning | Retina | Retinoprotection | Developmental Biology | Biomedicine general | Cell Biology | SURGERY | ACTIVATION | ISOFLURANE | INJURY | NEUROPROTECTION | DEGENERATION | CELL BIOLOGY | INHIBITION | GANGLION-CELLS | K-ATP CHANNEL | BRAIN | Eye - pathology | Carotid Arteries | Eye - blood supply | Rats, Wistar | Rats | Ischemic Preconditioning - methods | Animals | Eye - drug effects | Methyl Ethers - administration & dosage | Retinal Degeneration - pathology | Retina - pathology | Ischemia - pathology | Retinal Ganglion Cells - drug effects
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16. Full Text Photoperiod differentially affects energetics of immunity in pregnant and lactating Siberian hamsters (Phodopus sungorus)
by Nelson R.J and Drazen D.L and Trasy A
Canadian Journal of Zoology, ISSN 0008-4301, 08/2003, Volume 81, Issue 8, pp. 1406 - 1413
Both immune and reproductive (i.e., pregnancy and lactation) functions are energetically demanding processes that fluctuate seasonally. Winter is energetically... 
ENERGY-BALANCE | THERMOGENESIS | SYSTEM | RESPONSES | ZOOLOGY | IMMUNOSUPPRESSION | LIFE-HISTORY | TRADE-OFFS | SYRIAN-HAMSTERS | ECOLOGICAL IMMUNOLOGY | REPRODUCTION
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17. Full Text Continuous central venous oxygen saturation assisted intraoperative hemodynamic management during major abdominal surgery improves outcome
by Trasy, D and Mikor, A and Nemeth, MF and Kovacs, I and Demeter, G and Molnar, Z
EUROPEAN JOURNAL OF ANAESTHESIOLOGY, ISSN 0265-0215, 06/2014, Volume 31, pp. 62 - 63
ANESTHESIOLOGY
Conference Proceeding
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18. Full Text INCREASING PROCALCITONIN KINETICS MAY BE A GOOD INDICATOR OF INFECTION IN CRITICALLY ILL PATIENTS
by Oveges, N and Trasy, D and Nemeth, MF and Tanczos, K and Osztroluczki, A and Fazakas, J and Hankovszky, P and Hajdu, E and Molnar, Z
INTENSIVE CARE MEDICINE, ISSN 0342-4642, 09/2014, Volume 40, pp. S262 - S262
CRITICAL CARE MEDICINE
Conference Proceeding
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19. Full Text EARLY PROCALCITONIN KINETICS MAY INDICATE EFFECTIVE EMPIRICAL ANTIBIOTIC THERAPY WITHIN HOURS AFTER STARTING TREATMENT EA PILOT STUDY
by Trasy, D and Nemeth, M and Osztroluczki, A and Tanczos, K and Oveges, N and Hankovszky, P and Molnar, Z
INTENSIVE CARE MEDICINE, ISSN 0342-4642, 10/2013, Volume 39, pp. S278 - S278
CRITICAL CARE MEDICINE
Conference Proceeding
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20. Full Text INCREASE IN PROCALCITONIN KINETICS MAY BE A GOOD INDICATOR OF STARTLING EMPIRICAL ANTIBIOTIC TREATMENT IN CRITICALLY ILL PATIENTS (A PILOT STUDY)
by Nemeth, M and Trasy, D and Osztroluczki, A and Tanczos, K and Lovas, A and Molnar, Z
INTENSIVE CARE MEDICINE, ISSN 0342-4642, 10/2013, Volume 39, pp. S280 - S280
CRITICAL CARE MEDICINE
Conference Proceeding
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