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science & technology (22) 22
cell biology (19) 19
life sciences & biomedicine (19) 19
humans (16) 16
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biochemistry & molecular biology (11) 11
ubiquitin (11) 11
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cyclin f (5) 5
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biology (4) 4
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phosphorylation (4) 4
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ribonucleoside diphosphate reductase - metabolism (4) 4
skp cullin f-box protein ligases - metabolism (4) 4
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anaphase-promoting complex-cyclosome (2) 2
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1. Full Text A cyclin without cyclin-dependent kinases: cyclin F controls genome stability through ubiquitin-mediated proteolysis
by D’Angiolella, Vincenzo and Esencay, Mine and Pagano, Michele
Trends in cell biology, ISSN 0962-8924, 2012, Volume 23, Issue 3, pp. 135 - 140
Pathology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Cycle - genetics | Genomic Instability | Signal Transduction | SKP Cullin F-Box Protein Ligases - genetics | Humans | Cyclins - genetics | Gene Expression Regulation | Ubiquitin - metabolism | Ribonucleoside Diphosphate Reductase - genetics | SKP Cullin F-Box Protein Ligases - metabolism | Ubiquitin - genetics | Protein Subunits - metabolism | Animals | Cyclins - metabolism | Proteolysis | Ribonucleoside Diphosphate Reductase - metabolism | Genome, Human | Protein Subunits - genetics | Ubiquitin | Ligases | Phosphotransferases | Genomics | Index Medicus | Cyclin-dependent kinase | Reviews | Cell cycle | Centrosomes | Oscillations | Cyclin F | Genomes | Spindles | Ubiquitin-protein ligase | deoxyribonucleotides | Cancer
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2. Full Text Beyond survival: fine‐tuning GTP production to boost melanoma invasion
by D'Angiolella, Vincenzo
Pigment cell and melanoma research, ISSN 1755-1471, 03/2014, Volume 27, Issue 2, pp. 159 - 161
Oncology | Life Sciences & Biomedicine | Dermatology | Science & Technology | Cell Biology | Melanoma - enzymology | Purine Nucleosides - biosynthesis | Animals | GMP Reductase - metabolism | Humans | Melanoma
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3. Full Text Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation
by Pfister, Sophia X and Markkanen, Enni and Jiang, Yanyan and Sarkar, Sovan and Woodcock, Mick and Orlando, Giulia and Mavrommati, Ioanna and Pai, Chen-Chun and Zalmas, Lykourgos-Panagiotis and Drobnitzky, Neele and Dianov, Grigory L and Verrill, Clare and Macaulay, Valentine M and Ying, Songmin and La Thangue, Nicholas B and D’Angiolella, Vincenzo and Ryan, Anderson J and Humphrey, Timothy C
Cancer cell, ISSN 1535-6108, 11/2015, Volume 28, Issue 5, pp. 557 - 568
WEE1 inhibitor | KDM4A | SETD2 | DNA replication | RRM2 | histone modification | synthetic lethality | CDK | ChIP | H3.3K36M | H3K36me3 | AZD1775 | epigenetic target | iPOND | ATR inhibitor | CHK1 inhibitor | cancer | Synthetic lethality | IPOND | Histone modification | Epigenetic target | Cancer | Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Neoplasms - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | Cell Survival - genetics | Molecular Sequence Data | Nucleotides - genetics | Neoplasms - prevention & control | Cell Cycle Proteins - antagonists & inhibitors | Protein-Tyrosine Kinases - genetics | Neoplasms - genetics | RNA Interference | Base Sequence | Cell Cycle Proteins - genetics | Lysine - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Ribonucleoside Diphosphate Reductase - metabolism | Nuclear Proteins - genetics | Pyrazoles - pharmacology | Amino Acid Sequence | Cell Survival - drug effects | Histone-Lysine N-Methyltransferase - genetics | Cell Cycle Proteins - metabolism | Pyrimidinones | Nuclear Proteins - metabolism | Ribonucleoside Diphosphate Reductase - genetics | Pyrimidines - pharmacology | Nucleotides - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Sequence Homology, Nucleic Acid | Blotting, Western | Sequence Homology, Amino Acid | Xenograft Model Antitumor Assays | Lysine - genetics | Animals | Histones - genetics | Histone-Lysine N-Methyltransferase - metabolism | Methylation - drug effects | Mice, Nude | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice, Inbred BALB C | Histones - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Medical colleges | Starvation | Hospitals | Epigenetic inheritance | Index Medicus
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4. Full Text Two paths to let the replisome go
by D'Angiolella, Vincenzo and Guardavaccaro, Daniele
Cell death and differentiation, ISSN 1350-9047, 07/2017, Volume 24, Issue 7, p. 1140
Molecular Biology | Journal Article | Cell Biology
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5. Full Text Two paths to let the replisome go
by D'Angiolella, Vincenzo and Guardavaccaro, Daniele
Cell death and differentiation, ISSN 1350-9047, 07/2017, Volume 24, Issue 7, pp. 1140 - 1141
Journal Article | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Mitosis | DNA Replication | Index Medicus | and
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6. Full Text The role of E3 ubiquitin ligases in the development and progression of glioblastoma
by Humphreys, Luke M and Smith, Paul and Chen, Zhuoyao and Fouad, Shahd and D'Angiolella, Vincenzo
Cell death and differentiation, ISSN 1350-9047, 01/2021, Volume 28, Issue 2, pp. 522 - 537
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Ubiquitin | Brain cancer | Glioblastoma | Malignancy | Kinases | DNA repair | Proteins | Signal transduction | Ionizing radiation | Ubiquitination | Blood-brain barrier | Proteolysis | Glioma cells | Protein-tyrosine kinase receptors | Chimeras | Protein-tyrosine kinase | Ubiquitin-protein ligase | Tyrosine | Therapeutic applications | MAP kinase | Patients | Chemotherapy | Medical prognosis | Stem cells | Tumors | Index Medicus | CNS cancer | Review | Ubiquitin ligases
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7. Full Text SCF Cyclin F controls centrosome homeostasis and mitotic fidelity through CP110 degradation
by Saraf, Anita and Florens, Laurence and Donato, Valerio and Pagano, Michele and Dynlacht, Brian and Washburn, Michael P and D'Angiolella, Vincenzo and Vijayakumar, Sangeetha
Nature (London), ISSN 0028-0836, 07/2010, Volume 466, Issue 7302, pp. 138 - 142
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8. Full Text Keeping CDK18 in balance to prevent DNA replication stress in breast cancer
by Braams, Esmée and D'Angiolella, Vincenzo
Oncotarget, ISSN 1949-2553, 12/2018, Volume 9, Issue 102, pp. 37610 - 37611
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9. Full Text USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110
by Li, Ji and D'Angiolella, Vincenzo and Seeley, E. Scott and Kim, Sehyun and Kobayashi, Tetsuo and Fu, Wenxiang and Campos, Eric I and Pagano, Michele and Dynlacht, Brian David
Nature (London), ISSN 0028-0836, 03/2013, Volume 495, Issue 7440, pp. 255 - 259
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Line | Microtubule-Associated Proteins - metabolism | Humans | Cell Cycle Proteins - metabolism | Homeostasis | SKP Cullin F-Box Protein Ligases - metabolism | Phosphoproteins - metabolism | Centrosome - metabolism | Neoplasms - therapy | Ubiquitination | Animals | Cell Cycle | Cyclins - metabolism | Ubiquitin Thiolesterase - metabolism | Centrioles - metabolism | Protein Stability | Neoplasms - pathology | Physiological aspects | Protein biosynthesis | Centrioles | Research | Cellular control mechanisms | Centrosomes | Proteins | Cell cycle | Tumors | Index Medicus
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10. Full Text SCFCyclin F controls centrosome homeostasis and mitotic fidelity through CP110 degradation
by D'Angiolella, Vincenzo and Donato, Valerio and Vijayakumar, Sangeetha and Saraf, Anita and Florens, Laurence and Washburn, Michael P and Dynlacht, Brian and Pagano, Michele
Nature (London), ISSN 0028-0836, 07/2010, Volume 466, Issue 7302, pp. 138 - U161
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology
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11. Full Text Cyclin F-Mediated Degradation of Ribonucleotide Reductase M2 Controls Genome Integrity and DNA Repair
by D'Angiolella, Vincenzo and Donato, Valerio and Forrester, Frances M and Jeong, Yeon-Tae and Pellacani, Claudia and Kudo, Yasusei and Saraf, Anita and Florens, Laurence and Washburn, Michael P and Pagano, Michele
Cell (Cambridge), ISSN 0092-8674, 05/2012, Volume 149, Issue 5, pp. 1023 - 1034
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genomic Instability | Down-Regulation | Humans | Cell Cycle Proteins - metabolism | Ataxia Telangiectasia Mutated Proteins | Amino Acid Motifs | Cell Nucleus - metabolism | Cyclins - metabolism | DNA Repair | Cell Line, Tumor | G2 Phase | DNA Damage | Ribonucleoside Diphosphate Reductase - metabolism | Protein-Serine-Threonine Kinases - metabolism | Proteins | Ubiquitin | Ligases | DNA damage | DNA | Genomics | DNA synthesis | Universities and colleges | DNA repair | Mass spectrometry | Protein binding | Index Medicus | Phosphorylation | ribonucleotides | F-box protein | Genotoxicity | protein purification | Mass spectroscopy | Genomes | deoxyribonucleotides | DNA biosynthesis | Ribonucleoside-triphosphate reductase | Cyclin F | Ubiquitin-protein ligase
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12. Full Text Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase
by Chen, Zhuoyao and Picaud, Sarah and Filippakopoulos, Panagis and D'Angiolella, Vincenzo and Bullock, Alex N
Structure (London), ISSN 0969-2126, 09/2019, Volume 27, Issue 9, pp. 1395 - 1404.e4
BTB | crystallography | autophagy | ubiquitination | CUL3 | Cullin-RING ligase | protein-protein interaction | cancer | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Adaptor Proteins, Signal Transducing - chemistry | Protein Structure, Secondary | Humans | Death-Associated Protein Kinases - metabolism | Models, Molecular | Crystallography, X-Ray | Death-Associated Protein Kinases - chemistry | Ubiquitination | Proteolysis | HEK293 Cells | Hydrophobic and Hydrophilic Interactions | Protein Binding | Protein Domains | Female | Adaptor Proteins, Signal Transducing - metabolism | Binding Sites | Ubiquitin | Cysteine | Peptides | Ligases | Crystals | Tryptophan | Structure | Alzheimer's disease | Protein-protein interactions | Index Medicus
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