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1. Full Text Mortality risk attributable to high and low ambient temperature: a multicountry observational study
by Gasparrini, Antonio, Dr and Guo, Yuming, PhD and Hashizume, Masahiro, Prof and Lavigne, Eric, PhD and Zanobetti, Antonella, PhD and Schwartz, Joel, Prof and Tobias, Aurelio, PhD and Tong, Shilu, Prof and Rocklöv, Joacim, PhD and Forsberg, Bertil, Prof and Leone, Michela, MS and De Sario, Manuela, MS and Bell, Michelle L, Prof and Guo, Yue-Liang Leon, MD and Wu, Chang-fu, PhD and Kan, Haidong, Prof and Yi, Seung-Muk, Prof and de Sousa Zanotti Stagliorio Coelho, Micheline, PhD and Saldiva, Paulo Hilario Nascimento, Prof and Honda, Yasushi, Prof and Kim, Ho, Prof and Armstrong, Ben, Prof and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Epidemiologi och global hälsa and Umeå universitet and Yrkes- och miljömedicin
Lancet, The, ISSN 0140-6736, 2015, Volume 386, Issue 9991, pp. 369 - 375
Summary Background Although studies have provided estimates of premature deaths attributable to either heat or cold in selected countries, none has so far... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | RED-CELL COUNTS | IMPACT | WEATHER | METAANALYSIS | EPIDEMIOLOGIC EVIDENCE | WINTER | BLOOD-VISCOSITY | COLD | CEREBRAL THROMBOSIS | HEAT WAVES | Risk Assessment - methods | Climate | Hot Temperature - adverse effects | Humans | Mortality | Global Health - statistics & numerical data | Cold Temperature - adverse effects | Brazil | Australia | Health aspects | Environmental health | Studies | Outdoor air quality | Climate change | Temperature | Heat | Sensitivity analysis | Cold | Research | Health risk assessment | Hälsovetenskaper | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Medical and Health Sciences | Medicin och hälsovetenskap | Public Health, Global Health, Social Medicine and Epidemiology | Health Sciences
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2. Full Text Evaluating the impact of Florida's "stand your ground" self-defense lawon homicide and suicide by firearm: An interrupted time series study
by Humphreys, David K and Gasparrini, Antonio and Wiebe, Douglas J
JAMA Internal Medicine, ISSN 2168-6106, 01/2017, Volume 177, Issue 1, pp. 44 - 50
IMPORTANCE In 2005, Florida amended its self-defense laws to provide legal immunity to individuals using lethal force in self-defense. The enactment of "stand... 
REGRESSION | MEDICINE, GENERAL & INTERNAL | CRIME | RACE
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3. Full Text Modeling Future Projections of Temperature-Related Excess Morbidity due to Infectious Gastroenteritis under Climate Change Conditions in Japan
by Onozuka, D and Gasparrini, A and Sera, F and Hashizume, M and Honda, Y
ENVIRONMENTAL HEALTH PERSPECTIVES, ISSN 0091-6765, 07/2019, Volume 127, Issue 7, pp. 77006 - 77006
BACKGROUND: Climate change has marked implications for the burden of infectious diseases. However, no studies have estimated future projections of climate... 
SYSTEMATIC ANALYSIS | GLOBAL BURDEN | MORTALITY | METAANALYSIS | TIME-SERIES ANALYSIS | WEATHER VARIABILITY | AMBIENT-TEMPERATURE | DIARRHEAL DISEASES | SEASONALITY | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | TOXICOLOGY | DEVELOPING-COUNTRIES | Disease | General circulation models | Time series analysis | Gastroenteritis | Mortality | Time series | Variations | Diarrhea | Viruses | Systematic review | Epidemiology | Empirical analysis | Morbidity | Emissions | Confidence intervals | Studies | Climate change | Heterogeneity | Infectious diseases | Surveillance | Temperature effects | Spatial heterogeneity | Public health | Low temperature | Index Medicus
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4. Full Text Towards more comprehensive projections of urban heat-related mortality: Estimates for New York city under multiple population, adaptation, and climate scenarios
by Petkova, Elisaveta P and Vink, Jan K and Horton, Radley M and Gasparrini, Antonio and Bader, Daniel A and Francis, Joe D and Kinney, Patrick L
Environmental Health Perspectives, ISSN 0091-6765, 01/2017, Volume 125, Issue 1, pp. 47 - 55
BACKGROUND: High temperatures have substantial impacts on mortality and, with growing concerns about climate change, numerous studies have developed... 
PUBLIC-HEALTH | CITIES | PART II | COUPLED MODEL | SIMULATION | FORMULATION | VARIABILITY | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | TEMPERATURE | EARTH SYSTEM MODEL | TOXICOLOGY | IMPACTS | Adaptation, Physiological | Models, Theoretical | Climate Change | Risk Assessment | Extreme Heat | Humans | Acclimatization | New York City - epidemiology | Mortality - trends | Environmental Exposure - statistics & numerical data | Forecasting | New York | Forecasts and trends | Atmospheric temperature | Health aspects | Mortality | Urban health | Climate | Temperature | Demography | Cold | General circulation models | Global climate models | Climate models | Studies | Climate change | Demographics | Heat | Census of Population | Temperature effects | Fatalities | Cities | Parks & recreation areas | Adaptation | Vital statistics | Index Medicus | Research
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5. Full Text Genomic and functional techniques to mine the microbiome for novel antimicrobials and antimicrobial resistance genes
by Adu‐Oppong, Boahemaa and Gasparrini, Andrew J and Dantas, Gautam
Annals of the New York Academy of Sciences, ISSN 0077-8923, 01/2017, Volume 1388, Issue 1, pp. 42 - 58
Microbial communities contain diverse bacteria that play important roles in every environment. Advances in sequencing and computational methodologies over the... 
antimicrobials | antimicrobial resistance | microbiome | metagenomics | NATURAL-PRODUCTS | MULTIDISCIPLINARY SCIENCES | ANTIBIOTIC-RESISTANCE | BACTERIAL | DISCOVERY | METAGENOMIC INVESTIGATIONS | DNA | EFFLUX PUMPS | BETA-LACTAMASES | TETRACYCLINE | MOLECULAR-MECHANISMS | Drug Resistance - genetics | Genomics - methods | Microbiota - genetics | Anti-Infective Agents | Genetic research | Drug resistance in microorganisms | Phylogeny | Genes | Methods | Public health | Drug resistance | Antimicrobial agents | Biosynthesis
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6. Full Text Nanoscale organization and dynamics of the siglec CD22 cooperate with the cytoskeleton in restraining BCR signalling
by Gasparrini, Francesca and Feest, Christoph and Bruckbauer, Andreas and Mattila, Pieta K and Müller, Jennifer and Nitschke, Lars and Bray, Dennis and Batista, Facundo D
The EMBO Journal, ISSN 0261-4189, 02/2016, Volume 35, Issue 3, pp. 258 - 280
Receptor organization and dynamics at the cell membrane are important factors of signal transduction regulation. Using super‐resolution microscopy and... 
B‐cell receptor signalling | siglec CD22 | glycoprotein CD45 | super‐resolution microscopy | membrane dynamics | B-cell receptor signalling | super-resolution microscopy | LIGAND-BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | CIS LIGANDS | TRANSLATIONAL DIFFUSION | UNMASKED CD22 | NEGATIVE REGULATOR | CELL BIOLOGY | TYROSINE-PHOSPHATASE 1C | IN-VIVO | B-CELL ACTIVATION | CLASS-II | MEMBRANE-RECEPTORS | B-Lymphocytes - cytology | Animals | Sialic Acid Binding Ig-like Lectin 2 - metabolism | Signal Transduction | Mice, Inbred C57BL | B-Lymphocytes - physiology | Cytoskeleton - metabolism | Mice, Inbred BALB C | Receptors, Antigen, B-Cell - metabolism | Microscopy, Fluorescence | Immunology
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7. Full Text Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma
by Siming Zhao and Murim Choi and John D. Overton and Stefania Bellone and Dana M. Roque and Emiliano Cocco and Federica Guzzo and Diana P. English and Joyce Varughese and Sara Gasparrini and Ileana Bortolomai and Natalia Buza and Pei Hui and Maysa Abu-Khalaf and Antonella Ravaggi and Eliana Bignotti and Elisabetta Bandiera and Chiara Romani and Paola Todeschini and Renata Tassi and Laura Zanotti and Luisa Carrara and Sergio Pecorelli and Dan-Arin Silasi and Elena Ratner and Masoud Azodi and Peter E. Schwartz and Thomas J. Rutherford and Amy L. Stiegler and Shrikant Mane and Titus J. Boggon and Joseph Schlessinger and Richard P. Lifton and Alessandro D. Santin
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 8, pp. 2916 - 2921
Uterine serous carcinoma (USC) is a biologically aggressive subtype of endometrial cancer. We analyzed the mutational landscape of USC by whole-exome... 
Somatic mutation | Exome | Phenotypes | Genes | DNA | Genetic mutation | Chromosomes | Sequencing | Tumors | Cancer | Endometrial carcinoma | Uterine serous papillary cancer | Cancer genomics | ACTIVATION | CYCLIN D1 | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | endometrial carcinoma | IDENTIFICATION | GENOME | uterine serous papillary cancer | UBIQUITIN LIGASE COMPLEX | cancer genomics | TUMOR-SUPPRESSOR | OVARIAN | HUMAN CANCERS | ABERRATIONS | Sequence Homology, Amino Acid | Uterine Neoplasms - genetics | Amino Acid Sequence | Animals | Humans | Molecular Sequence Data | Female | Base Pair Mismatch | Mutation | DNA Copy Number Variations | Carcinoma | Physiological aspects | Development and progression | Genetic aspects | Single nucleotide polymorphisms | Research | Uterine tumors | DNA repair | Biological Sciences
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8. Full Text Autophagy in Human Health and Disease: Novel Therapeutic Opportunities
by Giampieri, Francesca and Afrin, Sadia and Forbes-Hernandez, Tamara Y and Gasparrini, Massimiliano and Cianciosi, Danila and Reboredo-Rodriguez, Patricia and Varela-Lopez, Alfonso and Quiles, Jose L and Battino, Maurizio
Antioxidants & Redox Signaling, ISSN 1523-0864, 02/2019, Volume 30, Issue 4, pp. 577 - 634
Significance: In eukaryotes, autophagy represents a highly evolutionary conserved process, through which macromolecules and cytoplasmic material are degraded... 
Comprehensive Invited Review | epigenetic modification | autophagy | disease prevention | natural bioactive compounds | molecular targets | FED C57BL/6J MICE | REDUCING OXIDATIVE STRESS | INDUCED RENAL DAMAGE | ACTIVATED PROTEIN-KINASE | CHAPERONE-MEDIATED AUTOPHAGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA (A-BETA(1-42))-INDUCED PARALYSIS | NECROSIS-FACTOR-ALPHA | BREAST-CANCER CELLS | TRAUMATIC BRAIN-INJURY | ENDOCRINOLOGY & METABOLISM | HYPOXIA-INDUCED AUTOPHAGY
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9. Full Text Temperature variability and mortality: A multi-country study
by Guo, Yuming and Gasparrini, Antonio and Armstrong, Ben G and Tawatsupa, Benjawan and Tobias, Aurelio and Lavigne, Eric and Zanotti Stagliorio Coelho, Micheline de Sousa and Pan, Xiaochuan and Kim, Ho and Hashizume, Masahiro and Honda, Yasushi and Guo, Yue Leon and Wu, Chang-Fu and Zanobetti, Antonella and Schwartz, Joel D and Bell, Michelle L and Overcenco, Ala and Punnasiri, Kornwipa and Li, Shanshan and Tian, Linwei and Saldiva, Paulo and Williams, Gail and Tong, Shilu
Environmental Health Perspectives, ISSN 0091-6765, 10/2016, Volume 124, Issue 10, pp. 1554 - 1559
BACKGROUND: The evidence and method are limited for the associations between mortality and temperature variability (TV) within or between days. OBJECTIVES: We... 
ADMISSIONS | ASSOCIATIONS | OUTDOOR TEMPERATURE | CHINA | AMBIENT-TEMPERATURE | LAG NONLINEAR MODELS | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | HEAT ACCLIMATION | EPIDEMIOLOGIC EVIDENCE | TIME-SERIES | TOXICOLOGY | RANGE | Canada | Analysis | Mortality | Japan | Climatic changes | Thailand | Health aspects | Risk factors | Outdoor air quality | Temperature | Statistical analysis | Cold | Time series | Estimates | Studies | Weather | Datasets | Climate change | Data collection | Standard deviation | Seasons | Cities | Health risk assessment | Research
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10. Full Text Projected temperature-related deaths in ten large U.S. metropolitan areas under different climate change scenarios
by Weinberger, Kate R and Haykin, Leah and Eliot, Melissa N and Schwartz, Joel D and Gasparrini, Antonio and Wellenius, Gregory A
Environment International, ISSN 0160-4120, 10/2017, Volume 107, pp. 196 - 204
There is an established U-shaped association between daily temperature and mortality. Temperature changes projected through the end of century are expected to... 
Climate change | Health impacts | Ambient temperature | United States | COLD-RELATED MORTALITY | WAVE | ENVIRONMENTAL SCIENCES | IMPACT | ACCLIMATIZATION | MORBIDITY | HEAT-RELATED MORTALITY | HEALTH | Models, Theoretical | Temperature | Climate Change | Humans | Mortality | Cities | Global temperature changes | Analysis | Environmental health | Environmental aspects | Metropolitan areas | Air pollution | Greenhouse gases | ambient temperature | climate change | health impacts
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11. Full Text Temporal variation in heat–mortality associations: A multicountry study
by Gasparrini, Antonio and Guo, Yuming and Hashizume, Masahiro and Kinney, Patrick L and Petkova, Elisaveta P and Lavigne, Eric and Zanobetti, Antonella and Schwartz, Joel D and Tobias, Aurelio and Leone, Michela and Tong, Shilu and Honda, Yasushi and Kim, Ho and Armstrong, Ben G
Environmental Health Perspectives, ISSN 0091-6765, 11/2015, Volume 123, Issue 11, pp. 1200 - 1207
Recent investigations have reported a decline in the heat-related mortality risk during the last decades. However, these studies are frequently based on... 
UNITED-STATES | PUBLIC-HEALTH | SUMMER TEMPERATURE | AMBIENT-TEMPERATURE | CLIMATE-CHANGE | VULNERABILITY | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | NEW-YORK-CITY | UNCERTAINTY ANALYSIS | TIME-SERIES | TOXICOLOGY | IMPACTS | Models, Theoretical | Seasons | Hot Temperature - adverse effects | Time Factors | Humans | Mortality | Environmental aspects | Health aspects | Hot weather | Index Medicus | Research
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