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07/2018
são fornecidas nesse relatório descritivo muteínas de il-2, moléculas de fusão muteína de il-2-fc, anticorpos anti-il-2, e complexos que compreendem um... 
METALLURGY | PEPTIDES | ORGANIC CHEMISTRY | CHEMISTRY
Patent
06/2018
Provided herein are IL-2 muteins, IL-2 mutein Fc-fusion molecules, anti-IL-2 antibodies, and complexes comprising an anti IL-2 antibody bound to an IL-2... 
METALLURGY | PEPTIDES | ORGANIC CHEMISTRY | CHEMISTRY
Patent
12/2018
T 조절 세포를 우선적으로 증식시키고, 활성화시키고, 그리고 대규모 생산이 가능한 IL-2 뮤테인, IL-2 뮤테인 Fc-융합 분자, 항-IL-2 항체, 및 IL-2 사이토카인에 결합된 항 IL-2 항체를 포함하는 복합체가 본 명세서에 제공된다. 효과기 기능이 결여되거나 또는 상당히... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
02/2018
Se proporcionan aquí muteínas de IL-2, moléculas de fusión de muteína de IL-2 Fc, anticuerpos anti-IL-2 y complejos que comprenden un anticuerpo anti-IL-2... 
METALLURGY | PEPTIDES | ORGANIC CHEMISTRY | CHEMISTRY
Patent
01/2018
Se proporcionan aquí muteínas de IL-2, moléculas de fusión de muteína de IL-2 Fc, anticuerpos anti-IL-2 y complejos que comprenden un anticuerpo anti-IL-2... 
METALLURGY | PEPTIDES | ORGANIC CHEMISTRY | CHEMISTRY
Patent
01/2018
referido a una muteina de interleucina-2 (IL-2) humana, moleculas de fusion de muteina de IL-2 Fc, anticuerpos anti-IL-2 y complejos que comprenden dicho... 
METALLURGY | PEPTIDES | ORGANIC CHEMISTRY | CHEMISTRY
Patent
Autoimmunity, ISSN 0891-6934, 2009, Volume 42, Issue 3, pp. 171 - 182
IP-10 secretion is induced by pro-inflammatory cytokines and mediates the migration of CXCR3+ cells. Its elevation in clinical samples has been associated with... 
mouse | chemokine | Inflammation | IP-10 | monoclonal antibody | Chemokine | Monoclonal antibody | Mouse | RHEUMATOID-ARTHRITIS | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | CHEMOKINE RECEPTOR CXCR3 | AIRWAY HYPERREACTIVITY | LIGAND IP-10 | IMMUNOLOGY | IFN-INDUCIBLE PROTEIN-10 | MULTIPLE-SCLEROSIS | INTERFERON-GAMMA | ACUTE ALLOGRAFT-REJECTION | T-CELLS | CD8-Positive T-Lymphocytes - cytology | Inflammation - pathology | Arthritis, Experimental - therapy | Antibodies, Monoclonal - therapeutic use | Male | Precursor Cells, B-Lymphoid - drug effects | Arthritis, Experimental - pathology | Cell Movement - immunology | Inflammatory Bowel Diseases - pathology | Chemokine CXCL10 - immunology | Female | Mice, Inbred DBA | Bronchoalveolar Lavage Fluid - cytology | Disease Models, Animal | Encephalomyelitis, Autoimmune, Experimental - pathology | Heart Transplantation - immunology | Antibodies, Monoclonal - pharmacology | Graft Rejection - prevention & control | Antibodies, Monoclonal - pharmacokinetics | Chemokine CXCL10 - antagonists & inhibitors | Treatment Outcome | Mice, Inbred Strains | Mice, SCID | Cell Movement - drug effects | Encephalomyelitis, Autoimmune, Experimental - therapy | Inflammation - therapy | Animals | CD8-Positive T-Lymphocytes - drug effects | Precursor Cells, B-Lymphoid - cytology | Mice | Mice, Inbred BALB C | Inflammatory Bowel Diseases - therapy
Journal Article
Arthritis & Rheumatism, ISSN 0004-3591, 04/2007, Volume 56, Issue 4, pp. 1145 - 1151
Journal Article
Arthritis & Rheumatism, ISSN 0004-3591, 09/2010, Volume 62, Issue 9, pp. 2716 - 2725
Journal Article
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