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humans (30) 30
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1. Full Text Germline BRCA Mutations Are Associated With Higher Risk of Nodal Involvement, Distant Metastasis, and Poor Survival Outcomes in Prostate Cancer
by Elena Castro and Chee Goh and David Olmos and Ed Saunders and Daniel Leongamornlert and Malgorzata Tymrakiewicz and Nadiya Mahmud and Tokhir Dadaev and Koveela Govindasami and Michelle Guy and Emma Sawyer and Rosemary Wilkinson and Audrey Ardern-Jones and Steve Ellis and Debra Frost and Susan Peock and D. Gareth Evans and Marc Tischkowitz and Trevor Cole and Rosemarie Davidson and Diana Eccles and Carole Brewer and Fiona Douglas and Mary E. Porteous and Alan Donaldson and Huw Dorkins and Louise Izatt and Jackie Cook and Shirley Hodgson and M. John Kennedy and Lucy E. Side and Jacqueline Eason and Alex Murray and Antonis C. Antoniou and Douglas F. Easton and Zsofia Kote-Jarai and Rosalind Eeles
Journal of Clinical Oncology, ISSN 0732-183X, 05/2013, Volume 31, Issue 14, pp. 1748 - 1757
To analyze the baseline clinicopathologic characteristics of prostate tumors with germline BRCA1 and BRCA2 (BRCA1/2) mutations and the prognostic value of... 
Predictive Value of Tests | Lymph Nodes - pathology | Prognosis | Follow-Up Studies | Humans | Middle Aged | Male | Prostatic Neoplasms - therapy | Neoplasm Grading | Prostatic Neoplasms - genetics | Antineoplastic Agents, Hormonal - therapeutic use | Nomograms | Aged, 80 and over | Germ-Line Mutation | Adult | Brachytherapy | Retrospective Studies | Radiotherapy, Adjuvant | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Lymphatic Metastasis | Prostatic Neoplasms - mortality | BRCA1 Protein - genetics | Phenotype | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Heterozygote | Prostatectomy | Aged | Neoplasm Staging | BRCA2 Protein - genetics | Palliative Care - methods | Dxst3 | Original Reports | Guc54 | Guc49
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2. Full Text Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
by Eeles, Rosalind A and Olama, Ali Amin Al and Benlloch, Sara and Saunders, Edward J and Leongamornlert, Daniel A and Tymrakiewicz, Malgorzata and Ghoussaini, Maya and Luccarini, Craig and Dennis, Joe and Jugurnauth-Little, Sarah and Dadaev, Tokhir and Neal, David E and Hamdy, Freddie C and Donovan, Jenny L and Muir, Ken and Giles, Graham G and Severi, Gianluca and Wiklund, Fredrik and Gronberg, Henrik and Haiman, Christopher A and Schumacher, Fredrick and Henderson, Brian E and Le Marchand, Loic and Lindstrom, Sara and Kraft, Peter and Hunter, David J and Gapstur, Susan and Chanock, Stephen J and Berndt, Sonja I and Albanes, Demetrius and Andriole, Gerald and Schleutker, Johanna and Weischer, Maren and Canzian, Federico and Riboli, Elio and Key, Tim J and Travis, Ruth C and Campa, Daniele and Ingles, Sue A and John, Esther M and Hayes, Richard B and Pharoah, Paul D. P and Pashayan, Nora and Khaw, Kay-Tee and Stanford, Janet L and Ostrander, Elaine A and Signorello, Lisa B and Thibodeau, Stephen N and Schaid, Dan and Maier, Christiane and Vogel, Walther and Kibel, Adam S and Cybulski, Cezary and Lubinski, Jan and Cannon-Albright, Lisa and Brenner, Hermann and Park, Jong Y and Kaneva, Radka and Batra, Jyotsna and Spurdle, Amanda B and Clements, Judith A and Teixeira, Manuel R and Dicks, Ed and Lee, Andrew and Dunning, Alison M and Baynes, Caroline and Conroy, Don and Maranian, Melanie J and Ahmed, Shahana and Govindasami, Koveela and Guy, Michelle and Wilkinson, Rosemary A and Sawyer, Emma J and Morgan, Angela and Dearnaley, David P and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Van As, Nicholas J and Woodhouse, Christopher J and Thompson, Alan and Dudderidge, Tim and Ogden, Chris and Cooper, Colin S and Lophatananon, Artitaya and Cox, Angela and Southey, Melissa C and Hopper, John L and English, Dallas R and Aly, Markus and Adolfsson, Jan and Xu, Jiangfeng and Zheng, Siqun L and Yeager, Meredith and Kaaks, Rudolf and Diver, W Ryan and Gaudet, Mia M and Stern, Mariana C and Corral, Roman and ... and UK Genetic Prostate Canc Study and Australian Prostate Canc and PRACTICAL Prostate Canc Assoc Grp and COGS-Canc Res UK GWAS-ELLIPSE Part and UK ProtecT Prostate Testing Canc and COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators and Australian Prostate Cancer Bioresource and PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The Australian Prostate Cancer Bioresource and The UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators and The COGS–Cancer Research UK GWAS–ELLIPSE (part of GAME-ON) Initiative and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology
Nature Genetics, ISSN 1061-4036, 04/2013, Volume 45, Issue 4, pp. 385 - 391
Prostate cancer is the most frequently diagnosed cancer in males in developed countries. To identify common prostate cancer susceptibility alleles, we... 
VARIANTS | PREDISPOSITION | MEN | GENETICS & HEREDITY | MUTATIONS | HOXB13 | GENOME-WIDE ASSOCIATION | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis as Topic | Oligonucleotide Array Sequence Analysis | Humans | Risk Factors | Genetic Loci - genetics | Prostatic Neoplasms - etiology | Cooperative Behavior | Genotype | Male | Case-Control Studies | Polymorphism, Single Nucleotide - genetics | Quantitative trait loci | Genetic susceptibility | Genetic aspects | Research | Prostate cancer | Identification and classification | Risk factors | Studies | Confidence intervals | Genotype & phenotype | Genealogy | Quality control | Cell cycle | Genomes | DNA repair | Deoxyribonucleic acid--DNA | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
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3. Full Text A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer
by Al Olama, Ali Amin and Kote-Jarai, Zsofia and Berndt, Sonja I and Conti, David V and Schumacher, Fredrick and Han, Ying and Benlloch, Sara and Hazelett, Dennis J and Wang, Zhaoming and Saunders, E and Leongamornlert, Daniel and Lindstrom, Sara and Jugurnauth-Little, Sara and Dadaev, Tokhir and Tymrakiewicz, Malgorzata and Stram, Daniel O and Rand, Kristin and Wan, Peggy and Stram, Alex and Sheng, Xin and Pooler, Loreall C and Park, Karen and Xia, Lucy and Tyrer, Jonathan and Kolonel, Laurence N and Le Marchand, Loic and Hoover, Robert N and Machiela, Mitchell J and Yeager, Merideth and Burdette, Laurie and Chung, Charles C and Hutchinson, Amy and Yu, Kai and Goh, Chee and Ahmed, Mahbubl and Govindasami, Koveela and Guy, Michelle and Tammela, Teuvo L J and Auvinen, Anssi and Wahlfors, Tiina and Schleutker, Johanna and Visakorpi, Tapio and Leinonen, Katri A and Xu, Jianfeng and Aly, Markus and Donovan, Jenny and Travis, Ruth C and Key, Tim J and Siddiq, Afshan and Canzian, Federico and Khaw, Kay-Tee and Takahashi, Atsushi and Kubo, Michiaki and Pharoah, Paul and Pashayan, Nora and Weischer, Maren and Nordestgaard, Borge G and Nielsen, Sune F and Klarskov, Peter and Røder, Martin Andreas and Iversen, Peter and Thibodeau, Stephen N and McDonnell, Shannon K and Schaid, Daniel J and Stanford, Janet L and Kolb, Suzanne and Holt, Sarah and Knudsen, Beatrice and Coll, Antonio Hurtado and Gapstur, Susan M and Diver, W Ryan and Stevens, Victoria L and Maier, Christiane and Luedeke, Manuel and Herkommer, Kathleen and Rinckleb, Antje E and Strom, Sara S and Pettaway, Curtis and Yeboah, Edward D and Tettey, Yao and Biritwum, Richard B and Adjei, Andrew A and Tay, Evelyn and Truelove, Ann and Niwa, Shelley and Chokkalingam, Anand P and Cannon-Albright, Lisa and Cybulski, Cezary and Wokołorczyk, Dominika and Kluźniak, Wojciech and Park, Jong and Sellers, Thomas and Lin, Hui-Yi and Isaacs, William B and Partin, Alan W and Brenner, Hermann and Dieffenbach, Aida Karina and Stegmaier, Christa and Chen, Constance and Giovannucci, Edward L and ... and Practical Prostate Canc Associatio and GAME-ON ELLIPSE Consortium and Breast Prostate Canc Cohort Consor and COGS Consortium and Breast and Prostate Cancer Cohort Consortium (BPC3) and GAME-ON/ELLIPSE Consortium and COGS (Collaborative Oncological Gene-environment Study) Consortium and PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The Breast and Prostate Cancer Cohort Consortium (BPC3) and The COGS (Collaborative Oncological Gene-environment Study) Consortium and The GAME-ON/ELLIPSE Consortium
Nature Genetics, ISSN 1061-4036, 09/2014, Volume 46, Issue 10, pp. 1103 - 1109
Genome-wide association studies (GWAS) have identified 76 variants associated with prostate cancer risk predominantly in populations of European ancestry. To... 
COMMON VARIANTS | GLIOMA | MEN | GENETICS & HEREDITY | RISK | JAPANESE | MYOSIN VI | 22Q13 | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Prostatic Neoplasms - genetics | Risk Assessment | Humans | Risk Factors | Genetic Loci - genetics | Genotype | Male | Polymorphism, Single Nucleotide | Quantitative trait loci | Genetic aspects | Prostate cancer | Identification and classification | Health aspects | Risk factors | Studies | Genealogy | Men | Genomes | Health risk assessment | Meta-analysis
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4. Full Text Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets
by Wedge, David C and Gundem, Gunes and Mitchell, Thomas and Woodcock, Dan J and Martincorena, Inigo and Ghori, Mohammed and Zamora, Jorge and Butler, Adam and Whitaker, Hayley and Kote-Jarai, Zsofia and Alexandrov, Ludmil B and Van Loo, Peter and Massie, Charlie E and Dentro, Stefan and Warren, Anne Y and Verrill, Clare and Berney, Dan M and Dennis, Nening and Merson, Sue and Hawkins, Steve and Howat, William and Lu, Yong-Jie and Lambert, Adam and Kay, Jonathan and Kremeyer, Barbara and Karaszi, Katalin and Luxton, Hayley and Camacho, Niedzica and Marsden, Luke and Edwards, Sandra and Matthews, Lucy and Bo, Valeria and Leongamornlert, Daniel and McLaren, Stuart and Ng, Anthony and Yu, Yongwei and Zhang, Hongwei and Dadaev, Tokhir and Thomas, Sarah and Easton, Douglas F and Ahmed, Mahbubl and Bancroft, Elizabeth and Fisher, Cyril and Livni, Naomi and Nicol, David and Tavaré, Simon and Gill, Pelvender and Greenman, Christopher and Khoo, Vincent and Van As, Nicholas and Kumar, Pardeep and Ogden, Christopher and Cahill, Declan and Thompson, Alan and Mayer, Erik and Rowe, Edward and Dudderidge, Tim and Gnanapragasam, Vincent and Shah, Nimish C and Raine, Keiran and Jones, David and Menzies, Andrew and Stebbings, Lucy and Teague, Jon and Hazell, Steven and Corbishley, Cathy and De Bono, Johann and Attard, Gerhardt and Isaacs, William and Visakorpi, Tapio and Fraser, Michael and Boutros, Paul C and Bristow, Robert G and Workman, Paul and Sander, Chris and Hamdy, Freddie C and Futreal, Andrew and McDermott, Ultan and Al-Lazikani, Bissan and Lynch, Andrew G and Bova, G. Steven and Foster, Christopher S and Brewer, Daniel S and Neal, David E and Cooper, Colin S and Eeles, Rosalind A and TCGA Consortium and CAMCAP Study Grp and CAMCAP Study Group and The TCGA Consortium
Nature Genetics, ISSN 1061-4036, 05/2018, Volume 50, Issue 5, pp. 682 - 692
Prostate cancer represents a substantial clinical challenge because it is difficult to predict outcome and advanced disease is often fatal. We sequenced the... 
ANDROGEN RECEPTOR | MUTATIONAL PROCESSES | METASTASIS | GROWTH | GENETICS & HEREDITY | TUMOR-SUPPRESSOR | COPY NUMBER ANALYSIS | DNA-REPAIR | DISCOVERY KNOWLEDGEBASE | EXPRESSION | SOMATIC MUTATIONS | Prostatic Neoplasms - pathology | Humans | Middle Aged | Male | Hepatocyte Nuclear Factor 3-alpha - genetics | Disease Progression | Prostatic Neoplasms - genetics | Aged, 80 and over | Adult | Aged | Mutation | High-Throughput Nucleotide Sequencing - methods | BRCA2 Protein - genetics | Oncogenes | Drugs | Medical research | Medical colleges | Genomics | Genes | Development and progression | Genomes | Metastasis | Drug approval | Medicine, Experimental | Genetic research | Genetic aspects | Prostate cancer | Cancer | Target recognition | Clinical trials | Cancer therapies | DNA repair | Metastases | Gene sequencing | Datasets | Bioinformatics | Deoxyribonucleic acid--DNA | BRCA2 protein | Breast cancer | Gene expression | Studies | Androgens | Computer applications | Prostate
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5. Full Text Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
by Kote-Jarai, Zsofia and Olama, Ali Amin Al and Giles, Graham G and Severi, Gianluca and Schleutker, Johanna and Weischer, Maren and Campa, Daniele and Riboli, Elio and Key, Tim and Gronberg, Henrik and Hunter, David J and Kraft, Peter and Thun, Michael J and Ingles, Sue and Chanock, Stephen and Albanes, Demetrius and Hayes, Richard B and Neal, David E and Hamdy, Freddie C and Donovan, Jenny L and Pharoah, Paul and Schumacher, Fredrick and Henderson, Brian E and Stanford, Janet L and Ostrander, Elaine A and Sorensen, Karina Dalsgaard and Dörk, Thilo and Andriole, Gerald and Dickinson, Joanne L and Cybulski, Cezary and Lubinski, Jan and Spurdle, Amanda and Clements, Judith A and Chambers, Suzanne and Aitken, Joanne and Gardiner, R. A. Frank and Thibodeau, Stephen N and Schaid, Dan and John, Esther M and Maier, Christiane and Vogel, Walther and Cooney, Kathleen A and Park, Jong Y and Cannon-Albright, Lisa and Brenner, Hermann and Habuchi, Tomonori and Zhang, Hong-Wei and Lu, Yong-Jie and Kaneva, Radka and Muir, Ken and Benlloch, Sara and Leongamornlert, Daniel A and Saunders, Edward J and Tymrakiewicz, Malgorzata and Mahmud, Nadiya and Guy, Michelle and O'Brien, Lynne T and Wilkinson, Rosemary A and Hall, Amanda L and Sawyer, Emma J and Dadaev, Tokhir and Morrison, Jonathan and Dearnaley, David P and Horwich, Alan and Huddart, Robert A and Khoo, Vincent S and Parker, Christopher C and Van As, Nicholas and Woodhouse, Christopher J and Thompson, Alan and Christmas, Tim and Ogden, Chris and Cooper, Colin S and Lophatonanon, Aritaya and Southey, Melissa C and Hopper, John L and English, Dallas R and Wahlfors, Tiina and Tammela, Teuvo L. J and Klarskov, Peter and Nordestgaard, Børge G and Røder, M Andreas and Tybjarg-Hansen, Anne and Bojesen, Stig E and Travis, Ruth and Canzian, Federico and Kaaks, Rudolf and Wiklund, Fredrik and Aly, Markus and Lindstrom, Sara and Diver, W Ryan and Gapstur, Susan and Stern, Mariana C and Corral, Roman and Virtamo, Jarmo and Cox, Angela and Haiman, Christopher A and Le Marchand, Loic and Fitzgerald, Liesel and Kolb, Suzanne and ... and UK ProtecT Study Collaborators and Australian Prostate Canc BioResour and PRACTCTICAL Consortium and UK Genetic Prostate Canc Study Col and PRACTICAL Consortium and UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and UK ProtecT Study Collaborators, The Australian Prostate Cancer BioResource and The PRACTICAL Consortium and The UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology and The UK ProtecT Study Collaborators, The Australian Prostate Cancer BioResource
Nature Genetics, ISSN 1061-4036, 08/2011, Volume 43, Issue 8, pp. 785 - 791
Prostate cancer (PrCa) is the most frequently diagnosed male cancer in developed countries. We conducted a multi-stage genome-wide association study for PrCa... 
SEQUENCE VARIANTS | GENETICS & HEREDITY | Genome-Wide Association Study | Disease Susceptibility | Chromosomes, Human - genetics | Humans | Middle Aged | Genotype | Male | Case-Control Studies | Randomized Controlled Trials as Topic | Prostatic Neoplasms - genetics | Telomerase - genetics | Aged, 80 and over | Polymorphism, Single Nucleotide - genetics | Adult | Aged | Genome, Human | Cohort Studies | Disease susceptibility | Genomes | Genetic aspects | Research | Single nucleotide polymorphisms | Prostate cancer | Risk factors | Genetics | Gene loci | Regression analysis
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6. Full Text Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
by Schumacher, Fredrick R and Al Olama, Ali Amin and Berndt, Sonja I and Benlloch, Sara and Ahmed, Mahbubl and Saunders, Edward J and Dadaev, Tokhir and Leongamornlert, Daniel and Anokian, Ezequiel and Cieza-Borrella, Clara and Goh, Chee and Brook, Mark N and Sheng, Xin and Fachal, Laura and Dennis, Joe and Tyrer, Jonathan and Muir, Kenneth and Lophatananon, Artitaya and Stevens, Victoria L and Gapstur, Susan M and Carter, Brian D and Tangen, Catherine M and Goodman, Phyllis J and Thompson, Ian M and Batra, Jyotsna and Chambers, Suzanne and Moya, Leire and Clements, Judith and Horvath, Lisa and Tilley, Wayne and Risbridger, Gail P and Gronberg, Henrik and Aly, Markus and Nordström, Tobias and Pharoah, Paul and Pashayan, Nora and Schleutker, Johanna and Tammela, Teuvo L. J and Sipeky, Csilla and Auvinen, Anssi and Albanes, Demetrius and Weinstein, Stephanie and Wolk, Alicja and Håkansson, Niclas and West, Catharine M. L and Dunning, Alison M and Burnet, Neil and Mucci, Lorelei A and Giovannucci, Edward and Andriole, Gerald L and Cussenot, Olivier and Cancel-Tassin, Géraldine and Koutros, Stella and Beane Freeman, Laura E and Sorensen, Karina Dalsgaard and Orntoft, Torben Falck and Borre, Michael and Maehle, Lovise and Grindedal, Eli Marie and Neal, David E and Donovan, Jenny L and Hamdy, Freddie C and Martin, Richard M and Travis, Ruth C and Key, Tim J and Hamilton, Robert J and Fleshner, Neil E and Finelli, Antonio and Ingles, Sue Ann and Stern, Mariana C and Rosenstein, Barry S and Kerns, Sarah L and Ostrer, Harry and Lu, Yong-Jie and Zhang, Hong-Wei and Feng, Ninghan and Mao, Xueying and Guo, Xin and Wang, Guomin and Sun, Zan and Giles, Graham G and Southey, Melissa C and MacInnis, Robert J and Fitzgerald, Liesel M and Kibel, Adam S and Drake, Bettina F and Vega, Ana and Gómez-Caamaño, Antonio and Szulkin, Robert and Eklund, Martin and Kogevinas, Manolis and Llorca, Javier and Castaño-Vinyals, Gemma and Penney, Kathryn L and Stampfer, Meir and Park, Jong Y and Sellers, Thomas A and Lin, Hui-Yi and Stanford, Janet L and Cybulski, Cezary and ... and Profile Study and Canary PASS Investigators and Canc Prostate Sweden CAPS and IMPACT Study and Prostate Canc Genome-wide As and APCB and Breast Prostate Canc Cohort Consor and PRACTICAL Prostate Canc As and Genetic Assoc Mech Oncology GAME and Breast and Prostate Cancer Cohort Consortium (BPC3) and Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS) and Australian Prostate Cancer BioResource (APCB) and Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium and Cancer of the Prostate in Sweden (CAPS) and PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The IMPACT Study and The Profile Study and The Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Ortopedi and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Nature Genetics, ISSN 1061-4036, 07/2018, Volume 50, Issue 7, pp. 928 - 936
Genome-wide association studies (GWAS) and fine-mapping efforts to date have identified more than 100 prostate cancer (PrCa)-susceptibility loci. We... 
CONSORTIUM | METAANALYSIS | GENE | VARIANTS | PATHWAY | GENETICS & HEREDITY | RISK | MULTIPLE LOCI | IDENTIFICATION | GENOME-WIDE ASSOCIATION | PREDICTION | Genetic Predisposition to Disease | Prostatic Neoplasms - genetics | Humans | Genotype | Male | Risk | Polymorphism, Single Nucleotide | Genetic Loci | Genome-Wide Association Study - methods | Case-Control Studies | Case studies | Genome-wide association studies | Usage | Men | Genetic aspects | Health aspects | Prostate cancer | Risk factors | Genealogy | Data processing | Genomes | Mapping | Biology | Family medical history | Loci | Meta-analysis | Confidence intervals | Consortia | Signal transduction | Software | Gene mapping | Health risk assessment | Prostate | Genotypes | Cancer | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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7. Full Text Correction: Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease
by Mijuskovic, Martina and Saunders, Edward J and Leongamornlert, Daniel A and Wakerell, Sarah and Whitmore, Ian and Dadaev, Tokhir and Cieza-Borrella, Clara and Govindasami, Koveela and Brook, Mark N and Haiman, Christopher A and Conti, David V and Eeles, Rosalind A and Kote-Jarai, Zsofia
British journal of cancer, ISSN 0007-0920, 04/2019, Volume 120, Issue 8, pp. 867 - 867
This article was originally published under the standard License to Publish, but has now been made available under a CC BY 4.0 license. The PDF and HTML... 
Angiogenesis | Prostate cancer | Prostate | DNA repair | Deoxyribonucleic acid--DNA | Metastases | Cancer | Cancer genetics
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8. Full Text Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease
by Mijuskovic, Martina and Saunders, Edward J and Leongamornlert, Daniel A and Wakerell, Sarah and Whitmore, Ian and Dadaev, Tokhir and Cieza-Borrella, Clara and Govindasami, Koveela and Brook, Mark N and Haiman, Christopher A and Conti, David V and Eeles, Rosalind A and Kote-Jarai, Zsofia
British Journal of Cancer, ISSN 0007-0920, 07/2018, Volume 119, Issue 1, pp. 96 - 104
BACKGROUND: Prostate cancer (PrCa) demonstrates a heterogeneous clinical presentation ranging from largely indolent to lethal. We sought to identify a... 
COUNTRIES | ONCOLOGY | MEN | FRAMEWORK | RISK | MUTATIONS | PREVALENCE | HOXB13 | ASSOCIATION | HERITABILITY | TOOL | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Genetic Association Studies | Humans | Middle Aged | Male | DNA Repair - genetics | Neovascularization, Pathologic - pathology | Whole Exome Sequencing | Neoplasm Metastasis | Prostatic Neoplasms - genetics | Cell Cycle Proteins - genetics | Polymorphism, Single Nucleotide - genetics | Neovascularization, Pathologic - genetics | Aged | Ataxia Telangiectasia Mutated Proteins - genetics | Nuclear Proteins - genetics | BRCA2 Protein - genetics | BRCA2 protein | Phenotypes | Genes | Breast cancer | Metastasis | DNA repair | Patients | Metastases | Proteins | Angiogenesis | Diagnosis | Repair | Prostate cancer | Bayesian analysis | Prostate | Deoxyribonucleic acid--DNA | Cancer
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9. Full Text Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
by Dadaev, Tokhir and Saunders, Edward J and Newcombe, Paul J and Anokian, Ezequiel and Leongamornlert, Daniel A and Brook, Mark N and Cieza-Borrella, Clara and Mijuskovic, Martina and Wakerell, Sarah and Olama, Ali Amin Al and Schumacher, Fredrick R and Berndt, Sonja I and Benlloch, Sara and Ahmed, Mahbubl and Goh, Chee and Sheng, Xin and Zhang, Zhuo and Muir, Kenneth and Govindasami, Koveela and Lophatananon, Artitaya and Stevens, Victoria L and Gapstur, Susan M and Carter, Brian D and Tangen, Catherine M and Goodman, Phyllis and Thompson, Ian M and Batra, Jyotsna and Chambers, Suzanne and Moya, Leire and Clements, Judith and Horvath, Lisa and Tilley, Wayne and Risbridger, Gail and Gronberg, Henrik and Aly, Markus and Nordström, Tobias and Pharoah, Paul and Pashayan, Nora and Schleutker, Johanna and Tammela, Teuvo L. J and Sipeky, Csilla and Auvinen, Anssi and Albanes, Demetrius and Weinstein, Stephanie and Wolk, Alicja and Hakansson, Niclas and West, Catharine and Dunning, Alison M and Burnet, Neil and Mucci, Lorelei and Giovannucci, Edward and Andriole, Gerald and Cussenot, Olivier and Cancel-Tassin, Géraldine and Koutros, Stella and Freeman, Laura E. Beane and Sorensen, Karina Dalsgaard and Orntoft, Torben Falck and Borre, Michael and Maehle, Lovise and Grindedal, Eli Marie and Neal, David E and Donovan, Jenny L and Hamdy, Freddie C and Martin, Richard M and Travis, Ruth C and Key, Tim J and Hamilton, Robert J and Fleshner, Neil E and Finelli, Antonio and Ingles, Sue Ann and Stern, Mariana C and Rosenstein, Barry and Kerns, Sarah and Ostrer, Harry and Lu, Yong-Jie and Zhang, Hong-Wei and Feng, Ninghan and Mao, Xueying and Guo, Xin and Wang, Guomin and Sun, Zan and Giles, Graham G and Southey, Melissa C and MacInnis, Robert J and Fitzgerald, Liesel M and Kibel, Adam S and Drake, Bettina F and Vega, Ana and Gómez-Caamaño, Antonio and Fachal, Laura and Szulkin, Robert and Eklund, Martin and Kogevinas, Manolis and Llorca, Javier and Castaño-Vinyals, Gemma and Penney, Kathryn L and Stampfer, Meir and Park, Jong Y and Sellers, Thomas A and ... and PRACTICAL Prostate Canc Assoc Grp and PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Ortopedi and Uppsala universitet and Institutionen för kirurgiska vetenskaper
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2256 - 19
Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified... 
ELEMENTS | RISK LOCI | GENETIC ASSOCIATION | BAYESIAN FRAMEWORK | MODEL SELECTION | ANNOTATION | MULTIDISCIPLINARY SCIENCES | VARIABLE-SELECTION | JOINT ANALYSIS | GENOME-WIDE ASSOCIATION | REGION | Multivariate Analysis | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Molecular Sequence Annotation | Male | Risk | Chromosome Mapping | Algorithms | Prostatic Neoplasms - genetics | Bayes Theorem | Polymorphism, Single Nucleotide | African Continental Ancestry Group - genetics | Quantitative Trait Loci | Pròstata | Càncer | Medical and Health Sciences | Medicin och hälsovetenskap
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