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science & technology (30) 30
life sciences & biomedicine (28) 28
prostate cancer (25) 25
humans (22) 22
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1. Full Text Germline BRCA Mutations Are Associated With Higher Risk of Nodal Involvement, Distant Metastasis, and Poor Survival Outcomes in Prostate Cancer
by Elena Castro and Chee Goh and David Olmos and Ed Saunders and Daniel Leongamornlert and Malgorzata Tymrakiewicz and Nadiya Mahmud and Tokhir Dadaev and Koveela Govindasami and Michelle Guy and Emma Sawyer and Rosemary Wilkinson and Audrey Ardern-Jones and Steve Ellis and Debra Frost and Susan Peock and D. Gareth Evans and Marc Tischkowitz and Trevor Cole and Rosemarie Davidson and Diana Eccles and Carole Brewer and Fiona Douglas and Mary E. Porteous and Alan Donaldson and Huw Dorkins and Louise Izatt and Jackie Cook and Shirley Hodgson and M. John Kennedy and Lucy E. Side and Jacqueline Eason and Alex Murray and Antonis C. Antoniou and Douglas F. Easton and Zsofia Kote-Jarai and Rosalind Eeles
Journal of clinical oncology, ISSN 0732-183X, 05/2013, Volume 31, Issue 14, pp. 1748 - 1757
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Multiple tumors. Solid tumors. Tumors in childhood (general aspects) | Medical sciences | Tumors | Predictive Value of Tests | Lymph Nodes - pathology | Prognosis | Follow-Up Studies | Humans | Middle Aged | Male | Prostatic Neoplasms - therapy | Neoplasm Grading | Prostatic Neoplasms - genetics | Antineoplastic Agents, Hormonal - therapeutic use | Nomograms | Aged, 80 and over | Germ-Line Mutation | Adult | Brachytherapy | Retrospective Studies | Radiotherapy, Adjuvant | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Lymphatic Metastasis | Prostatic Neoplasms - mortality | BRCA1 Protein - genetics | Phenotype | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Heterozygote | Prostatectomy | Aged | Neoplasm Staging | BRCA2 Protein - genetics | Palliative Care - methods | Index Medicus | Dxst3 | Original Reports | Guc54 | Guc49
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2. Full Text Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets
by Wedge, David C and Gundem, Gunes and Mitchell, Thomas and Woodcock, Dan J and Martincorena, Inigo and Ghori, Mohammed and Zamora, Jorge and Butler, Adam and Whitaker, Hayley and Kote-Jarai, Zsofia and Alexandrov, Ludmil B and Van Loo, Peter and Massie, Charlie E and Dentro, Stefan and Warren, Anne Y and Verrill, Clare and Berney, Dan M and Dennis, Nening and Merson, Sue and Hawkins, Steve and Howat, William and Lu, Yong-Jie and Lambert, Adam and Kay, Jonathan and Kremeyer, Barbara and Karaszi, Katalin and Luxton, Hayley and Camacho, Niedzica and Marsden, Luke and Edwards, Sandra and Matthews, Lucy and Bo, Valeria and Leongamornlert, Daniel and McLaren, Stuart and Ng, Anthony and Yu, Yongwei and Zhang, Hongwei and Dadaev, Tokhir and Thomas, Sarah and Easton, Douglas F and Ahmed, Mahbubl and Bancroft, Elizabeth and Fisher, Cyril and Livni, Naomi and Nicol, David and Tavaré, Simon and Gill, Pelvender and Greenman, Christopher and Khoo, Vincent and Van As, Nicholas and Kumar, Pardeep and Ogden, Christopher and Cahill, Declan and Thompson, Alan and Mayer, Erik and Rowe, Edward and Dudderidge, Tim and Gnanapragasam, Vincent and Shah, Nimish C and Raine, Keiran and Jones, David and Menzies, Andrew and Stebbings, Lucy and Teague, Jon and Hazell, Steven and Corbishley, Cathy and De Bono, Johann and Attard, Gerhardt and Isaacs, William and Visakorpi, Tapio and Fraser, Michael and Boutros, Paul C and Bristow, Robert G and Workman, Paul and Sander, Chris and Hamdy, Freddie C and Futreal, Andrew and McDermott, Ultan and Al-Lazikani, Bissan and Lynch, Andrew G and Bova, G. Steven and Foster, Christopher S and Brewer, Daniel S and Neal, David E and Cooper, Colin S and Eeles, Rosalind A and TCGA Consortium and CAMCAP Study Grp and CAMCAP Study Group and The TCGA Consortium
Nature genetics, ISSN 1061-4036, 05/2018, Volume 50, Issue 5, pp. 682 - 692
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Prostatic Neoplasms - pathology | Humans | Middle Aged | Male | Hepatocyte Nuclear Factor 3-alpha - genetics | Disease Progression | Prostatic Neoplasms - genetics | Aged, 80 and over | Adult | Aged | Mutation | High-Throughput Nucleotide Sequencing - methods | BRCA2 Protein - genetics | Oncogenes | Drugs | Medical research | Medical colleges | Genomics | Genes | Development and progression | Genomes | Metastasis | Drug approval | Medicine, Experimental | Genetic research | Genetic aspects | Prostate cancer | Cancer | Target recognition | Clinical trials | Cancer therapies | DNA repair | Metastases | Gene sequencing | Datasets | Bioinformatics | Deoxyribonucleic acid--DNA | BRCA2 protein | Breast cancer | Gene expression | Studies | Androgens | Computer applications | Prostate | Index Medicus
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3. Full Text Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease
by Mijuskovic, Martina and Saunders, Edward J and Leongamornlert, Daniel A and Wakerell, Sarah and Whitmore, Ian and Dadaev, Tokhir and Cieza-Borrella, Clara and Govindasami, Koveela and Brook, Mark N and Haiman, Christopher A and Conti, David V and Eeles, Rosalind A and Kote-Jarai, Zsofia
British journal of cancer, ISSN 0007-0920, 07/2018, Volume 119, Issue 1, pp. 96 - 104
Life Sciences & Biomedicine | Oncology | Science & Technology
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4. Full Text Correction: Rare germline variants in DNA repair genes and the angiogenesis pathway predispose prostate cancer patients to develop metastatic disease
by Mijuskovic, Martina and Saunders, Edward J and Leongamornlert, Daniel A and Wakerell, Sarah and Whitmore, Ian and Dadaev, Tokhir and Cieza-Borrella, Clara and Govindasami, Koveela and Brook, Mark N and Haiman, Christopher A and Conti, David V and Eeles, Rosalind A and Kote-Jarai, Zsofia
British journal of cancer, ISSN 0007-0920, 03/2019, Volume 120, Issue 8, pp. 867 - 867
Cancer genetics
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5. Full Text Effect of BRCA Mutations on Metastatic Relapse and Cause-specific Survival After Radical Treatment for Localised Prostate Cancer
by Castro, Elena and Goh, Chee and Leongamornlert, Daniel and Saunders, Ed and Tymrakiewicz, Malgorzata and Dadaev, Tokhir and Govindasami, Koveela and Guy, Michelle and Ellis, Steve and Frost, Debra and Bancroft, Elizabeth and Cole, Trevor and Tischkowitz, Marc and Kennedy, M. John and Eason, Jacqueline and Brewer, Carole and Evans, D. Gareth and Davidson, Rosemarie and Eccles, Diana and Porteous, Mary E and Douglas, Fiona and Adlard, Julian and Donaldson, Alan and Antoniou, Antonis C and Kote-Jarai, Zsofia and Easton, Douglas F and Olmos, David and Eeles, Rosalind
European urology, ISSN 0302-2838, 2014, Volume 68, Issue 2, pp. 186 - 193
Urology | Prognostic factor | Prostatectomy | BRCA1 | BRCA2 | Homologous repair | Radiotherapy | Prostate cancer | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Multivariate Analysis | Humans | Middle Aged | Male | Prostatic Neoplasms - therapy | Neoplasm Metastasis | Prostatic Neoplasms - genetics | Time Factors | DNA Mutational Analysis | Germ-Line Mutation | Prostatic Neoplasms - blood | Kallikreins - blood | Retrospective Studies | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | United Kingdom | Prostatectomy - adverse effects | Prostate-Specific Antigen - blood | Prostatic Neoplasms - mortality | BRCA1 Protein - genetics | Disease-Free Survival | Phenotype | Prostatectomy - mortality | BRCA2 Protein - genetics | Index Medicus
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6. Full Text LocusExplorer: A user-friendly tool for integrated visualization of human genetic association data and biological annotations
by Dadaev, Tokhir and Leongamornlert, Daniel A and Saunders, Edward J and Eeles, Rosalind and Kote-Jarai, Zsofia
Bioinformatics, ISSN 1367-4803, 03/2016, Volume 32, Issue 6, pp. 949 - 951
Statistics & Probability | Biochemistry & Molecular Biology | Physical Sciences | Computer Science, Interdisciplinary Applications | Life Sciences & Biomedicine | Technology | Biochemical Research Methods | Computer Science | Mathematics | Biotechnology & Applied Microbiology | Science & Technology | Mathematical & Computational Biology | Programming Languages | Software | Genetics, Medical | Humans | Web Browser | Index Medicus | Human | Freeware | Zooming | Data visualization | Images | Genetics | Biological | Source code | Applications Notes
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7. Full Text Genome-wide association of familial prostate cancer cases identifies evidence for a rare segregating haplotype at 8q24.21
by Teerlink, Craig C and Leongamornlert, Daniel and Dadaev, Tokhir and Thomas, Alun and Farnham, James and Stephenson, Robert A and Riska, Shaun and McDonnell, Shannon K and Schaid, Daniel J and Catalona, William J and Zheng, S Lilly and Cooney, Kathleen A and Ray, Anna M and Zuhlke, Kimberly A and Lange, Ethan M and Giles, Graham G and Southey, Melissa C and Fitzgerald, Liesel M and Rinckleb, Antje and Luedeke, Manuel and Maier, Christiane and Stanford, Janet L and Ostrander, Elaine A and Kaikkonen, Elina M and Sipeky, Csilla and Tammela, Teuvo and Schleutker, Johanna and Wiley, Kathleen E and Isaacs, Sarah D and Walsh, Patrick C and Isaacs, William B and Xu, Jianfeng and Cancel-Tassin, Geraldine and Cussenot, Olivier and Mandal, Diptasri and Laurie, Cecelia and Laurie, Cathy and Thibodeau, Stephen N and Eeles, Rosalind A and Kote-Jarai, Zsofia and Cannon-Albright, Lisa and PRACTICAL Consortium Int and International Consortium for Prostate Cancer Genetics and PRACTICAL consortium and The PRACTICAL consortium
Human genetics, ISSN 0340-6717, 8/2016, Volume 135, Issue 8, pp. 923 - 938
Human Genetics | Gene Function | Molecular Medicine | Biomedicine | Metabolic Diseases | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Genome-Wide Association Study | Gene Frequency | Humans | Middle Aged | Risk Factors | Genotype | Male | RNA, Long Noncoding - genetics | Haplotypes - genetics | Prostatic Neoplasms - genetics | Pedigree | Tumor Suppressor Proteins - genetics | Heterozygote | Aged | Polymorphism, Single Nucleotide | Medical colleges | Analysis | Oncology, Experimental | Genomics | Genomes | Genetic aspects | Single nucleotide polymorphisms | Research | Health aspects | Cancer | Index Medicus
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8. Full Text Mutational signatures of ionizing radiation in second malignancies
by Behjati, Sam and Gundem, Gunes and Wedge, David C and Roberts, Nicola D and Tarpey, Patrick S and Cooke, Susanna L and Van Loo, Peter and Alexandrov, Ludmil B and Ramakrishna, Manasa and Davies, Helen and Nik-Zainal, Serena and Hardy, Claire and Latimer, Calli and Raine, Keiran M and Stebbings, Lucy and Menzies, Andy and Jones, David and Shepherd, Rebecca and Butler, Adam P and Teague, Jon W and Jorgensen, Mette and Khatri, Bhavisha and Pillay, Nischalan and Shlien, Adam and Futreal, P. Andrew and Badie, Christophe and McDermott, Ultan and Bova, G. Steven and Richardson, Andrea L and Flanagan, Adrienne M and Stratton, Michael R and Campbell, Peter J and Cooper, Colin S and Eeles, Rosalind A and Easton, Douglas and Foster, Christopher and Neal, David E and Brewer, Daniel S and Hamdy, Freddie and Lu, Yong-Jie and Lynch, Andrew G and Massi, Charlie E and Ng, Anthony and Whitaker, Hayley C and Yu, Yongwei and Zhang, Hongwei and Bancroft, Elizabeth and Berney, Dan and Camacho, Niedzica and Corbishley, Cathy and Dadaev, Tokhir and Dennis, Nening and Dudderidge, Tim and Edwards, Sandra and Fisher, Cyril and Ghori, Jilur and Gnanapragasam, Vincent J and Greenman, Christopher and Hawkins, Steve and Hazell, Steven and Howat, Will and Karaszi, Katalin and Kay, Jonathan and Kote-Jarai, Zsofia and Kremeyer, Barbara and Kumar, Pardeep and Lambert, Adam and Leongamornlert, Daniel and Livni, Naomi and Luxton, Hayley and Matthews, Lucy and Mayer, Erik and Merson, Susan and Nicol, David and Ogden, Christopher and O'Meara, Sarah and Pelvender, Gill and Shah, Nimish C and Tavare, Simon and Thomas, Sarah and Thompson, Alan and Verrill, Claire and Warren, Anne and Zamora, Jorge and ICGC Prostate Grp and ICGC Prostate Group
Nature communications, ISSN 2041-1723, 09/2016, Volume 7, Issue 1, pp. 12605 - 12605
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Index Medicus
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9. Full Text Gene and pathway level analyses of germline DNA-repair gene variants and prostate cancer susceptibility using the iCOGS-genotyping array
by Saunders, Edward J and Dadaev, Tokhir and Leongamornlert, Daniel A and Al Olama, Ali Amin and Benlloch, Sara and Giles, Graham G and Wiklund, Fredrik and Grönberg, Henrik and Haiman, Christopher A and Schleutker, Johanna and Nordestgaard, BØrge G and Travis, Ruth C and Neal, David and Pasayan, Nora and Khaw, Kay-Tee and Stanford, Janet L and Blot, William J and Thibodeau, Stephen N and Maier, Christiane and Kibel, Adam S and Cybulski, Cezary and Cannon-Albright, Lisa and Brenner, Hermann and Park, Jong Y and Kaneva, Radka and Batra, Jyotsna and Teixeira, Manuel R and Pandha, Hardev and Govindasami, Koveela and Muir, Ken and Easton, Douglas F and Eeles, Rosalind A and Kote-Jarai, Zsofia and PRACTICAL Consortium and UK ProtecT Study Collaborators and UK Genetic Prostate Canc Study Col and UK Genetic Prostate Cancer Study Collaborators and The UK Genetic Prostate Cancer Study Collaborators and The PRACTICAL Consortium Australian Prostate Cancer BioResource and The UK ProtecT Study Collaborators
British journal of cancer, ISSN 0007-0920, 04/2016, Volume 114, Issue 8, pp. 945 - 952
prostate cancer | GWAS | DNA repair | iCOGS | genome-wide association study | Life Sciences & Biomedicine | Oncology | Science & Technology | Genetic Predisposition to Disease - genetics | Prospective Studies | Humans | DNA Repair Enzymes - genetics | Genotype | Male | Risk | DNA Repair - genetics | DNA-Binding Proteins - genetics | Germ-Line Mutation - genetics | Case-Control Studies | DNA - genetics | BRCA1 Protein - genetics | Prostatic Neoplasms - genetics | Genes, BRCA2 - physiology | Cell Cycle Proteins - genetics | Polymorphism, Single Nucleotide - genetics | Genome-Wide Association Study - methods | Index Medicus | Genetics and Genomics | Medicin och hälsovetenskap
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