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Immunology, ISSN 0019-2805, 06/2019, Volume 157, Issue 2, pp. 163 - 172
Summary It is well understood that the STING signalling pathway is critical for generating a robust innate immune response to pathogens. Human and mouse STING... 
monocytes | cGAMP | innate immunology | inflammation | humanized mice | INTERFERON | MOUSE | TRAFFICKING | IL-2 | INNATE IMMUNE SENSOR | IMMUNOLOGY | Analysis | Hematopoietic stem cells | Spleen | Level (quantity) | Immune response | Analogue | Immunodeficiency | Stem cell transplantation | Signal transduction | Signaling | Monocytes | Lungs | Cord blood | Human response | Stem cells | Mice | Kinetics | Human behavior | Immune system
Journal Article
Molecular Therapy, ISSN 1525-0016, 2019, Volume 27, Issue 8, pp. 1424 - 1435
Song et al. describe an effective approach for arthritis therapy through delivery of the siRNA against IL-1β by a lipidoid-polymer hybrid nanoparticle... 
siRNA delivery | nanoparticles | IL-1β | rheumatoid arthritis | lipidoid | RHEUMATOID-ARTHRITIS | MEDICINE, RESEARCH & EXPERIMENTAL | CYTOKINES | DEXAMETHASONE | NANOMATERIALS | MECHANISMS | DELIVERY | CATIONIC LIPIDS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | INFLAMMATION | DISEASE | GENETICS & HEREDITY | TNF-ALPHA
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2012, Volume 122, Issue 4, pp. 1368 - 1376
Journal Article
Journal Article
The Journal of Gene Medicine, ISSN 1099-498X, 11/2012, Volume 14, Issue 11, pp. 632 - 641
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 1961, pp. 329 - 341
CRISPR/Cas9 technology allows facile modification of the genome in virtually any desired way through the use of easily designed plasmid constructs that express... 
Hydrodynamic tail vein injection | Indels | CRISPR/Cas9 | Genetic mouse models | Liver | Animals | RNA, Guide - genetics | Liver - metabolism | Plasmids - genetics | Mice | Hepatocytes - metabolism | CRISPR-Cas Systems - genetics | Gene Editing
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 06/2016, Volume 232, pp. 143 - 151
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 5/2016, Volume 131, Issue 5, pp. 775 - 791
Journal Article