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61. Full Text Respiratory Effects of the Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist, Cebranopadol, in Healthy Human Volunteers
by Dahan, Albert and Boom, Merel and Sarton, Elise and Hay, Justin and Groeneveld, Geert Jan and Neukirchen, Meike and Bothmer, John and Aarts, Leon and Olofsen, Erik
Anesthesiology (Philadelphia), ISSN 0003-3022, 04/2017, Volume 126, Issue 4, pp. 697 - 707
Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Young Adult | Receptors, Opioid - agonists | Humans | Middle Aged | Respiration - drug effects | Adolescent | Pain Threshold - drug effects | Adult | Indoles - pharmacology | Male | Reference Values | Spiro Compounds - pharmacology | Index Medicus | Abridged Index Medicus
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62. Full Text Cholinergic Chemotransmission and Anesthetic Drug Effects at the Carotid Bodies
by Honing, Maarten and Martini, Chris and van Velzen, Monique and Niesters, Marieke and Dahan, Albert and Boon, Martijn
Molecules (Basel, Switzerland), 12/2020, Volume 25, Issue 24, p. 5974
Chemoreception (internal) | Muscle relaxants | Carbon dioxide | Muscles | Nervous system | Permeability | Hypnotics | Mammals | Experiments | Muscle contraction | Cholinergics | Signal transduction | Neurotransmitters | Pain | Analgesics | Hypoxia | Anesthesia | Acidosis | Index Medicus | peripheral chemosensitivity | cholinergic transmission | muscle relaxants | anesthesia
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63. Full Text Reduced postoperative pain using Nociception Level-guided fentanyl dosing during sevoflurane anaesthesia: a randomised controlled trial
by Meijer, Fleur and Honing, Maarten and Roor, Tessa and Toet, Samantha and Calis, Paul and Olofsen, Erik and Martini, Chris and van Velzen, Monique and Aarts, Leon and Niesters, Marieke and Boon, Martijn and Dahan, Albert
British journal of anaesthesia : BJA, ISSN 0007-0912, 12/2020, Volume 125, Issue 6, pp. 1070 - 1078
nociception | nociception level-guided anaesthesia | stress hormones | postoperative pain | opioid | Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Anesthetics, Inhalation | Fentanyl - administration & dosage | Pain, Postoperative - drug therapy | Artificial Intelligence | Humans | Middle Aged | Male | Dose-Response Relationship, Drug | Sevoflurane | Anesthetics, Intravenous - administration & dosage | Nociception - drug effects | Monitoring, Intraoperative - methods | Adult | Female | Aged | Index Medicus | Pain
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64. Full Text Sex-specific responses to opiates: Animal and human studies
by Dahan, Albert and Kest, Benjamin and Waxman, Amanda R and Sarton, Elise
Anesthesia and analgesia, ISSN 0003-2999, 2008, Volume 107, Issue 1, pp. 83 - 95
Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Biological and medical sciences | Anesthesia | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Receptors, Opioid - agonists | Humans | Receptors, Opioid, kappa - agonists | Drug Tolerance | Analgesics, Opioid - pharmacology | Rats | Male | Receptors, Opioid, mu - agonists | Sex Characteristics | Gonadal Steroid Hormones - physiology | Animals | Female | Mice | Receptors, Opioid, delta - agonists | Index Medicus | Abridged Index Medicus
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65. Full Text Using Akaike's information theoretic criterion in mixed-effects modeling of pharmacokinetic data: a simulation study
by Olofsen, Erik and Dahan, Albert
F1000 research, ISSN 2046-1402, 2013, Volume 2, p. 71
Pharmacokinetics & Drug Delivery
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66. Full Text Tolerance to Opioid‐Induced Respiratory Depression in Chronic High‐Dose Opioid Users: A Model‐Based Comparison With Opioid‐Naïve Individuals
by Algera, Marijke Hyke and Olofsen, Erik and Moss, Laurence and Dobbins, Robert L and Niesters, Marieke and van Velzen, Monique and Groeneveld, Geert Jan and Heuberger, Jules and Laffont, Celine M and Dahan, Albert
Clinical pharmacology and therapeutics, ISSN 0009-9236, 03/2021, Volume 109, Issue 3, pp. 637 - 645
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Index Medicus | Abridged Index Medicus
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67. Full Text Using Akaike's information theoretic criterion in mixed-effects modeling of pharmacokinetic data: a simulation study
by Olofsen, Erik and Dahan, Albert
F1000 research, ISSN 2046-1402, 2013, Volume 2, pp. 71 - 71
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68. Full Text Nociception level monitoring for personalized analgesic treatment. Response to Br J Anaesth 2020; 125: 1070-8
by Meijer, Fleur and Honing, Maarten and Roor, Tessa and Toet, Samantha and Calis, Paul and Olofsen, Erik and Martini, Chris and van Velzen, Monique and Aarts, Leon and Niesters, Marieke and Boon, Martijn and Dahan, Albert
British journal of anaesthesia : BJA, ISSN 0007-0912, 02/2021, Volume 126, Issue 2, pp. e65 - e66
nociception level index | analgesia | fentanyl | opioid | SOLAR trial | remifentanil | NOLA trial | Nociception | Fentanyl | Anesthesia | Analgesics | Humans | Remifentanil | Index Medicus
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69. Full Text Pharmacokinetic Properties of a Sufentanil Sublingual Tablet Intended to Treat Acute Pain
by Fisher, Dennis M and Chang, Peter and Wada, D Russell and Dahan, Albert and Palmer, Pamela P
Anesthesiology (Philadelphia), ISSN 0003-3022, 03/2018, Volume 128, Issue 5, pp. 943 - 952
Acute Pain - drug therapy | Administration, Sublingual | Sufentanil - pharmacokinetics | Cytochrome P-450 CYP3A Inhibitors - pharmacology | Tablets | Humans | Middle Aged | Biological Availability | Male | Sufentanil - administration & dosage | Young Adult | Adolescent | Analgesics, Opioid - pharmacokinetics | Aged, 80 and over | Adult | Female | Aged | Care and treatment | Dosage and administration | Acute pain | Pharmacokinetics | Analysis | Sufentanil
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70. Full Text Two studies on reversal of opioid-induced respiratory depression by BK-channel blocker GAL021 in human volunteers
by Roozekrans, Margot and Roozekrans, Margot and van der Schrier, Rutger and Van Der Schrier, Rutger and Okkerse, Pieter and Okkerse, Pieter and Hay, Justin and Hay, Justin and McLeod, James F and McLeod, James F and Dahan, Albert and Dahan, Albert
Anesthesiology (Philadelphia), ISSN 0003-3022, 2014, Volume 121, Issue 3, pp. 459 - 468
Life Sciences & Biomedicine | Anesthesiology | Science & Technology | Biological and medical sciences | Anesthesia | Medical sciences | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Double-Blind Method | Triazines - therapeutic use | Humans | Middle Aged | Potassium Channel Blockers - therapeutic use | Male | Large-Conductance Calcium-Activated Potassium Channels - antagonists & inhibitors | Healthy Volunteers | Respiratory Insufficiency - chemically induced | Doxapram - therapeutic use | Cross-Over Studies | Analgesia | Analgesics, Opioid - adverse effects | Alfentanil - therapeutic use | Adolescent | Adult | Alfentanil - adverse effects | Hemodynamics - drug effects | Respiratory Insufficiency - drug therapy | Index Medicus | Abridged Index Medicus
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71. Full Text Translation of random painful stimuli into numerical responses in fibromyalgia and perioperative patients
by Oudejans, Linda and Van Velzen, Monique and Olofsen, Erik and Beun, Robert and Dahan, Albert and Niesters, Marieke
Pain (Amsterdam), ISSN 0304-3959, 10/2015, Volume 157, Issue 1, pp. 128 - 136
Measurement | Pain | Experimental pain | Fibromyalgia | Numerical rating scale | Modeling | Chronic pain | Neurosciences | Clinical Neurology | Anesthesiology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Severity of Illness Index | Pain Threshold - physiology | Electric Stimulation | Humans | Middle Aged | Male | Young Adult | Pain Measurement - methods | Fibromyalgia - diagnosis | Pain, Postoperative - diagnosis | Adolescent | Aged, 80 and over | Adult | Female | Aged | Fibromyalgia - physiopathology | Pain, Postoperative - physiopathology | Index Medicus
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72. Full Text Benefit and Risk Evaluation of Biased μ-Receptor Agonist Oliceridine versus Morphine
by Dahan, Albert and van Dam, C Jan and Niesters, Marieke and van Velzen, Monique and Fossler, Michael J and Demitrack, Mark A and Olofsen, Erik
Anesthesiology (Philadelphia), ISSN 0003-3022, 09/2020, Volume 133, Issue 3, pp. 559 - 568
Thiophenes - therapeutic use | Pain, Postoperative - drug therapy | Thiophenes - adverse effects | Humans | Middle Aged | Pain Management | Male | Spiro Compounds - therapeutic use | Receptors, Opioid, mu - agonists | Healthy Volunteers | Spiro Compounds - adverse effects | Young Adult | Analgesics, Opioid - adverse effects | Morphine - pharmacokinetics | Adult | Hypercapnia - physiopathology | Pulmonary Ventilation - drug effects | Risk Assessment | Analgesics, Opioid - therapeutic use | Respiratory Insufficiency - chemically induced | Spiro Compounds - pharmacokinetics | Thiophenes - pharmacokinetics | Analgesics, Opioid - pharmacokinetics | Pain Measurement | Morphine - administration & dosage | Morphine - therapeutic use | Index Medicus | Abridged Index Medicus
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73. Full Text 36: DERIVATION AND VALIDATION OF A NOVEL OPIOID-INDUCED RESPIRATORY DEPRESSION RISK PREDICTION TOOL
by Khanna, Ashish and Buhre, Wolfgang and Saager, Leif and Stefano, Paola Di and Weingarten, Toby and Dahan, Albert and Brazzi, Luca and Overdyk, Frank
Critical care medicine, ISSN 0090-3493, 01/2019, Volume 47, Issue 1 Suppl 1, pp. 18 - 18
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74. Pharmacovigilance: A review of opioid-induced respiratory depression in chronic pain patients
by Dahan, Albert and Overdyk, Frank and Smith, Terry and Aarts, Leon and Niesters, Marieke
Pain physician, ISSN 1533-3159, 03/2013, Volume 16, Issue 2, pp. E85 - E94
Opioid-induced respiratory depression | Pain | Case series | Toxicity | Chronic pain | Opioids | Clinical Neurology | Anesthesiology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Analgesics, Opioid - adverse effects | Chronic Pain - drug therapy | Humans | Middle Aged | Aged, 80 and over | Respiratory Insufficiency - epidemiology | Adult | Female | Male | Aged | Pharmacovigilance | Respiratory Insufficiency - chemically induced
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75. Full Text Early postoperative pain after laparoscopic donor nephrectomy predicts 30-day postoperative infectious complications: a pooled analysis of randomized controlled trials
by Albers, Kim I and van Helden, Esmee V and Dahan, Albert and Martini, Chris H and Bruintjes, Moira H.D and Scheffer, Gert Jan and Steegers, Monique A.H and Keijzer, Christiaan and Warlé, Michiel C
Pain (Amsterdam), ISSN 0304-3959, 07/2020, Volume 161, Issue 7, pp. 1565 - 1570
Anesthesiology and Pain Medicine | Neurology | Clinical Neurology
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76. Full Text Endogenous modulation of pain is visible in the brain
by Dahan, Albert and Niesters, Marieke and Sarton, Elise
Clinical neurophysiology, ISSN 1388-2457, 2011, Volume 123, Issue 4, pp. 642 - 643
Neurology | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Sigmoid Diseases - physiopathology | Conditioning (Psychology) - physiology | Pain - physiopathology | Brain - physiopathology | Humans | Rectal Diseases - physiopathology | Female | Male | Neural Pathways - physiopathology | Index Medicus
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