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life sciences & biomedicine (8) 8
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1. Full Text The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling
by Amano, Wataru, DVM and Nakajima, Saeko, MD, PhD and Kunugi, Hayato, PhD and Numata, Yasuharu, MS and Kitoh, Akihiko, MD, PhD and Egawa, Gyohei, MD, PhD and Dainichi, Teruki, MD, PhD and Honda, Tetsuya, MD, PhD and Otsuka, Atsushi, MD, PhD and Kimoto, Yukari, MS and Yamamoto, Yasuo, MS and Tanimoto, Atsuo, MS and Matsushita, Mutsuyoshi, PhD and Miyachi, Yoshiki, MD, PhD and Kabashima, Kenji, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 3, pp. 667 - 677.e7
Allergy and Immunology | keratinocyte differentiation | signal transducer and activator of transcription 3 | Atopic dermatitis | filaggrin | Janus kinase inhibitor | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | RNA, Small Interfering - genetics | Dermatitis, Atopic - genetics | Humans | Interleukin-13 - immunology | Transplantation, Heterologous | STAT6 Transcription Factor - genetics | Interleukin-13 - genetics | RNA, Small Interfering - immunology | Skin, Artificial | Dermatitis, Atopic - immunology | Intermediate Filament Proteins - genetics | Skin Transplantation | STAT6 Transcription Factor - antagonists & inhibitors | Interleukin-4 - genetics | STAT3 Transcription Factor - genetics | Disease Models, Animal | Intermediate Filament Proteins - immunology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Dermatitis, Atopic - pathology | STAT6 Transcription Factor - immunology | Keratinocytes - immunology | Interleukin-4 - immunology | Keratinocytes - pathology | Animals | Dermatitis, Atopic - drug therapy | Keratinocytes - drug effects | Cell Differentiation - drug effects | Mice, Nude | Mice | Protein Kinase Inhibitors - pharmacology | Immunocompromised Host | STAT3 Transcription Factor - immunology | STAT3 Transcription Factor - antagonists & inhibitors | Circuit components | Allergens | Mutual fund industry | Skin | Genetic transcription | Proteins | Cytokines | Genes | Skin & tissue grafts | Ligands | Kinases | Potassium | Chemokines | Index Medicus | Abridged Index Medicus
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2. Full Text Alopecia areata: What’s new in epidemiology, pathogenesis, diagnosis, and therapeutic options?
by Dainichi, Teruki, MD, PhD and Kabashima, Kenji, MD, PhD
Journal of dermatological science, ISSN 0923-1811, 2016, Volume 86, Issue 1, pp. 3 - 12
Dermatology | Autoimmunity | Genetics | Treatment | Diagnosis | Epidemiology | Alopecia areata | Life Sciences & Biomedicine | Science & Technology | Glucocorticoids - administration & dosage | Glucocorticoids - therapeutic use | Immunotherapy - methods | Humans | Dermoscopy | Alopecia Areata - diagnosis | Autoimmune Diseases - etiology | Incidence | T-Lymphocytes, Regulatory - immunology | Alopecia Areata - therapy | Alopecia Areata - epidemiology | Hair Follicle - immunology | Chemokines - immunology | Autoimmune Diseases - epidemiology | Autoimmune Diseases - diagnosis | Biomarkers - blood | Pulse Therapy, Drug | Phototherapy | Alopecia Areata - etiology | Autoantibodies - immunology | Autoantigens - immunology | Autoimmune Diseases - therapy | Quality of Life | Administration, Topical | Cryotherapy | Practice Guidelines as Topic | Medical colleges | Care and treatment | Alopecia | Baldness | Health aspects | Index Medicus
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3. Full Text Receptor-interacting protein kinase 3 controls keratinocyte activation in a necroptosis-independent manner and promotes psoriatic dermatitis in mice
by Honda, Tetsuya, MD, PhD and Yamamoto, Osamu, MD, PhD and Sawada, Yu, MD, PhD and Egawa, Gyohei, MD, PhD and Kitoh, Akihiko, MD, PhD and Otsuka, Atsushi, MD, PhD and Dainichi, Teruki, MD, PhD and Nakajima, Saeko, MD, PhD and Miyachi, Yoshiki, MD, PhD and Kabashima, Kenji, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2017, Volume 140, Issue 2, pp. 619 - 622.e6
Allergy and Immunology | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Apoptosis - genetics | Necrosis - metabolism | Neutrophil Infiltration | Mice, Knockout | Keratinocytes - pathology | Psoriasis - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Psoriasis - pathology | Keratinocytes - metabolism | Psoriasis - metabolism | Biomarkers | Mice | Necrosis - genetics | Disease Models, Animal | Medical colleges | College teachers | Psoriasis | Protein kinases | Flow cytometry | Inflammatory bowel diseases | Dehydrogenases | Pathogenesis | Hyperplasia | Inflammatory response | Activation | Interleukin 24 | Kinases | Dermatitis | Inflammatory diseases | Proteins | Systemic inflammatory response syndrome | Intestine | Rodents | Sodium sulfate | Bone marrow | Tumor necrosis factor-TNF | Skin diseases | Lesions | Cytokines | Dendritic cells | Neutrophils | Organs | Keratinocytes | Epidermis | Leukocytes (neutrophilic) | Inflammation | Hazards | Gene expression | Inflammatory bowel disease | Polymerase chain reaction | Dextran | Sodium | Protein kinase | Infiltration | Software | Colitis | Sulfate | Chemokines | Apoptosis | Index Medicus | Abridged Index Medicus
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4. Full Text Local inflammation exacerbates cutaneous manifestations in a murine autoimmune pemphigus model
by Ono, Sachiko, MD and Egawa, Gyohei, MD, PhD and Kitoh, Akihiko, MD, PhD and Dainichi, Teruki, MD, PhD and Otsuka, Atsushi, MD, PhD and Nakajima, Saeko, MD, PhD and Honda, Tetsuya, MD, PhD and Kabashima, Kenji, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2017, Volume 139, Issue 6, pp. 2026 - 2028.e5
Allergy and Immunology | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Autoimmunity | Inflammation - pathology | Epidermal Cells - immunology | Humans | Immunoglobulin G | Autoimmune Diseases - immunology | Epidermal Cells - metabolism | Inflammation - immunology | Disease Progression | Phenotype | Animals | Pemphigus - pathology | Biomarkers | Epidermal Cells - pathology | Pemphigus - immunology | Mice | Autoimmune Diseases - pathology | Skin - pathology | Disease Models, Animal | Skin - immunology | Medical colleges | Lupus | Antigens | Dermatology | Pemphigus | Antibodies | Epidermis | Inflammation | Radiation dosage | Microscopy | Cell adhesion | Ear | Blistering | Skin | Index Medicus | Abridged Index Medicus
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5. Full Text IgA pemphigus
by Tsuruta, Daisuke, MD, PhD and Ishii, Norito, MD, PhD and Hamada, Takahiro, MD, PhD and Ohyama, Bungo, MD, PhD and Fukuda, Shunpei, MD and Koga, Hiroshi, MD and Imamura, Kazuko, MD and Kobayashi, Hiromi, MD, PhD and Karashima, Tadashi, MD, PhD and Nakama, Takekuni, MD and Dainichi, Teruki, MD, PhD and Hashimoto, Takashi, MD
Clinics in dermatology, ISSN 0738-081X, 2011, Volume 29, Issue 4, pp. 437 - 442
Dermatology | Life Sciences & Biomedicine | Science & Technology | Prevalence | Humans | Middle Aged | Child, Preschool | Infant | Male | Incidence | Desmosomes - pathology | Young Adult | Desmosomes - immunology | Aged, 80 and over | Adult | Female | Pemphigus - epidemiology | Child | Neutrophils - pathology | Neutrophils - immunology | Pemphigus - classification | Desmocollins - immunology | Autoantibodies - immunology | Immunoglobulin A - immunology | Pemphigus - pathology | Adolescent | Pemphigus - immunology | Aged | Immunoglobulin A | Pemphigus | Index Medicus
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6. Full Text A case of epidermolysis bullosa acquisita with clinical features of Brunsting-Perry pemphigoid showing an excellent response to colchicine
by Tanaka, Noriko, MD and Dainichi, Teruki, MD and Ohyama, Bungo, MD and Yasumoto, Shinichiro, MD and Oono, Takashi, MD and Iwatsuki, Keiji, MD and Elfert, Susanne and Fritsch, Anja, PhD and Bruckner-Tuderman, Leena, MD and Hashimoto, Takashi, MD
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2009, Volume 61, Issue 4, pp. 715 - 719
Dermatology | epidermolysis bullosa acquisita | type VII collagen | Brunsting-Perry pemphigoid | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Bullous diseases of the skin | Epidermolysis Bullosa Acquisita - immunology | Humans | Collagen Type VII - immunology | Pemphigoid, Bullous - drug therapy | Colchicine - administration & dosage | Epidermolysis Bullosa Acquisita - drug therapy | Pemphigoid, Bullous - pathology | Epitopes - immunology | Tubulin Modulators - administration & dosage | Female | Aged | Pemphigoid, Bullous - immunology | Epidermolysis Bullosa Acquisita - pathology | Autoimmunity | Medical colleges | Autoantigens | Colchicine | Index Medicus
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7. Full Text Low‐dose cyclosporin improves the health‐related quality of life in Japanese psoriasis patients dissatisfied with topical corticosteroid monotherapy
by Hashimoto, Takashi and Kawakami, Tamihiro and Tsuruta, Daisuke and Hamada, Takahiro and Natsuaki, Yohei and Fukuda, Shunpei and Koga, Hiroshi and Sogame, Ryosuke and Ohyama, Bungo and Ono, Fumitake and Karashima, Tadashi and Nakama, Takekuni and Dainichi, Teruki and Ishii, Norito and Yasumoto, Shinichiro
Australasian journal of dermatology, ISSN 0004-8380, 08/2012, Volume 53, Issue 3, pp. 202 - 206
patient satisfaction | psoriasis area and severity index | psoriasis | health‐related quality of life | the dermatology life quality index | cyclosporin | topical corticosteroid | health-related quality of life | Life Sciences & Biomedicine | Dermatology | Science & Technology | Biological and medical sciences | Medical sciences | Psoriasis. Parapsoriasis. Lichen | Pharmacology. Drug treatments | Bones, joints and connective tissue. Antiinflammatory agents | Severity of Illness Index | Psoriasis - drug therapy | Humans | Japan | Middle Aged | Male | Adrenal Cortex Hormones - therapeutic use | Patient Satisfaction | Cyclosporine - administration & dosage | Quality of Life | Adult | Female | Aged | Immunosuppressive Agents - administration & dosage | Medical colleges | Dosage and administration | Corticosteroids | Patient satisfaction | Psoriasis | Steroids | Index Medicus
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8. Full Text Development of Multiple Paronychia and Periungual Granulation in Patients Treated with Gefitinib, an Inhibitor of Epidermal Growth Factor Receptor
by Dainichi, Teruki and Tanaka, Maya and Tsuruta, Nobuko and Furue, Masutaka and Noda, Keishi
Dermatology (Basel), ISSN 1018-8665, 2003, Volume 207, Issue 3, pp. 324 - 325
Letters to Dermatology | Non-small-cell lung cancer | Paronychia | Periungual granulation | Gefitinib | Epidermal growth factor receptor | Life Sciences & Biomedicine | Dermatology | Science & Technology | Paronychia - chemically induced | Severity of Illness Index | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Follow-Up Studies | Risk Assessment | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Lung Neoplasms - pathology | Male | Nail Diseases - therapy | Combined Modality Therapy | Adenocarcinoma - drug therapy | Nail Diseases - chemically induced | Quinazolines - therapeutic use | Quinazolines - adverse effects | Nail Diseases - physiopathology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Female | Paronychia - physiopathology | Paronychia - therapy
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