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Journal of Clinical Investigation, ISSN 0021-9738, 09/2017, Volume 127, Issue 9, pp. 3462 - 3471
Journal Article
Molecular Therapy, ISSN 1525-0016, 09/2017, Volume 25, Issue 9, pp. 2214 - 2224
Targeting disialoganglioside (GD2) on neuroblastoma (NB) with T cells expressing a first-generation chimeric antigen receptor (CAR) was safe, but the cells had... 
neuroblastoma | GD2-CAR | immunotherapy | MEDICINE, RESEARCH & EXPERIMENTAL | NKT CELLS | ANTI-GD2 ANTIBODY | ANTITUMOR-ACTIVITY | THERAPY | IMMUNOTHERAPY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | TUMOR-ASSOCIATED MACROPHAGES | SUPPRESSOR-CELLS | BLOCKADE | ANTIGEN RECEPTOR | STAGE 4 NEUROBLASTOMA | Antineoplastic Agents, Immunological - administration & dosage | Humans | Child, Preschool | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Neuroblastoma - mortality | Neuroblastoma - therapy | Lymphocyte Depletion | Molecular Targeted Therapy | Recombinant Fusion Proteins | Young Adult | T-Lymphocytes - metabolism | Neuroblastoma - immunology | Female | Child | Neuroblastoma - pathology | Cytokines - blood | Immunotherapy, Adoptive - adverse effects | Immunotherapy, Adoptive - methods | Receptors, Antigen, T-Cell - metabolism | Treatment Outcome | Combined Modality Therapy | Antineoplastic Agents, Immunological - adverse effects | Antineoplastic Agents, Immunological - therapeutic use | Adolescent | Lymphocyte Count | Myeloid Cells - metabolism | T-Lymphocytes - immunology | Receptors, Antigen, T-Cell - genetics | Transplantation Conditioning | Cohort Studies | Antigens | Lymphatic system | Myeloid cells | CD11b antigen | PD-1 protein | Lymphocytes T | Neuroblastoma | Metastasis | Patients | Fever | CD45 antigen | Blood | CD163 antigen | Cyclophosphamide | Pain | Fludarabine | Lymphocytes | Bone marrow | Antitumor activity | Movement disorders | Apoptosis | Neutropenia | Index Medicus | Original
Journal Article
Cell Reports, ISSN 2211-1247, 10/2017, Volume 21, Issue 1, pp. 17 - 26
Antigen-independent tonic signaling by chimeric antigen receptors (CARs) can increase differentiation and exhaustion of T cells, limiting their potency.... 
adoptive T cell therapy | 4-1BB | chimeric antigen receptor | costimulation | T cells | adoptive T cell therapy | ACTIVATION | LIGAND EXPRESSION | CAR | EFFECTOR FUNCTION | GENE-EXPRESSION | FAS | DEATH | ANTITUMOR-ACTIVITY | NF-KAPPA-B | SIGNALING COMPLEX | CELL BIOLOGY | Neoplasm Transplantation | Humans | Mutant Chimeric Proteins - genetics | NF-kappa B - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 9 - genetics | T-Lymphocytes - transplantation | Leukemia-Lymphoma, Adult T-Cell - immunology | Lentivirus - metabolism | fas Receptor - immunology | Cell Death | fas Receptor - genetics | Lentivirus - genetics | Receptors, Antigen, T-Cell - immunology | 4-1BB Ligand - immunology | T-Lymphocytes - pathology | 4-1BB Ligand - genetics | Antigens, Neoplasm - genetics | Genetic Vectors - chemistry | Signal Transduction | Antigens, Neoplasm - immunology | Cell Survival | Leukemia-Lymphoma, Adult T-Cell - genetics | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | Genetic Vectors - metabolism | Gene Expression Regulation, Leukemic | Leukemia-Lymphoma, Adult T-Cell - pathology | Gammaretrovirus - metabolism | Animals | Gammaretrovirus - genetics | NF-kappa B - genetics | Mice, Inbred NOD | Mutant Chimeric Proteins - immunology | T-Lymphocytes - immunology | Mice | Receptors, Antigen, T-Cell - genetics | Index Medicus | Chimeric antigen receptor
Journal Article
Oncogene, ISSN 0950-9232, 06/2014, Volume 33, Issue 24, pp. 3099 - 3108
Journal Article
Tarih Kültür ve Sanat Araştırmaları Dergisi, 06/2017, Volume 6, Issue 3, pp. 1555 - 1566
The Government of the Russian Federation has been overhauling a public sector of economy since 2010. One of the transformation’s goals is a gradual reduction... 
Institutional risks, Public sector organizations, Institutional environment, Target indicators, Institutional traps
Journal Article
Blood, ISSN 0006-4971, 06/2014, Volume 123, Issue 24, pp. 3750 - 3759
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2015, Volume 33, Issue 15, pp. 1688 - 1696
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 12/2018, Volume 26, Issue 12, pp. 2727 - 2737
Second-generation (2G) chimeric antigen receptors (CARs) targeting CD19 are highly active against B cell malignancies, but it is unknown whether any of the... 
second-generation CAR | chimeric antigen receptor | third-generation CAR | CAR-T cells | CD19 | immunotherapy | Antigens | CD19 antigen | Cytotoxicity | T cell receptors | Lymphocytes T | CD28 antigen | Patients | Lymphoma | Interleukin 6 | Chemotherapy | Pain | Lymphocytes B | Lymphocytes | Neutropenia
Journal Article
Journal Article