Journal of the American Chemical Society, ISSN 0002-7863, 10/2014, Volume 136, Issue 39, pp. 13522 - 13525
The total synthesis of two key analogues of vancomycin containing single-atom exchanges in the binding pocket (residue 4 amidine and thioamide) are disclosed...
Binding | Synthesis | MRSA | Pocket | Bacteria | Derivatives | Vancomycin | Antiinfectives and antibacterials | Communication
Binding | Synthesis | MRSA | Pocket | Bacteria | Derivatives | Vancomycin | Antiinfectives and antibacterials | Communication
Journal Article
Nuclear Physics, Section B, ISSN 0550-3213, 06/2016, Volume 907, pp. 717 - 763
The production of , and charmed mesons has been measured with the ATLAS detector in collisions at at the LHC, using data corresponding to an integrated...
Fysik | Subatomär fysik | Physical Sciences | Subatomic Physics | Naturvetenskap | Natural Sciences
Fysik | Subatomär fysik | Physical Sciences | Subatomic Physics | Naturvetenskap | Natural Sciences
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 01/2012, Volume 134, Issue 2, pp. 1284 - 1297
The total synthesis of [Ψ[C(S)NH]Tpg4]vancomycin aglycon (8) and its unique AgOAc-promoted single-step conversion to [Ψ[C(NH)NH]Tpg4]vancomycin aglycon (7),...
Anti-Bacterial Agents - chemical synthesis | Amino Acid Sequence | Vancomycin - chemical synthesis | Peptidoglycan - chemistry | Vancomycin - analogs & derivatives | Drug Resistance, Bacterial | Models, Molecular | Protein Binding | Molecular Structure
Anti-Bacterial Agents - chemical synthesis | Amino Acid Sequence | Vancomycin - chemical synthesis | Peptidoglycan - chemistry | Vancomycin - analogs & derivatives | Drug Resistance, Bacterial | Models, Molecular | Protein Binding | Molecular Structure
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 03/2006, Volume 128, Issue 9, pp. 2885 - 2892
An effective synthesis of [Psi[CH2NH]Tpg(4)]vancomycin aglycon (5) is detailed in which the residue 4 amide carbonyl of vancomycin aglycon has been replaced...
GLYCOPEPTIDE ANTIBIOTICS | TEICOPLANIN AGLYCON | AMINO-ACID | PART 3 | RESISTANCE | RING-SYSTEMS | THERMAL ATROPISOMERISM | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | COUPLING REAGENT | Carbonyl compounds | Vancomycin | Chemical properties | Structure | Chemical synthesis
GLYCOPEPTIDE ANTIBIOTICS | TEICOPLANIN AGLYCON | AMINO-ACID | PART 3 | RESISTANCE | RING-SYSTEMS | THERMAL ATROPISOMERISM | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | COUPLING REAGENT | Carbonyl compounds | Vancomycin | Chemical properties | Structure | Chemical synthesis
Journal Article
Cancer Epidemiology Biomarkers and Prevention, ISSN 1055-9965, 12/2017, Volume 26, Issue 12, pp. 1761 - 1771
Background: We previously observed that high serum 25-hydroxyvitamin D (25(OH) D; >38.0 ng/mL) was inversely associated with breast cancer. Here, we examined...
CONSORTIUM | WOMEN | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | VARIANTS | ONCOLOGY | VDR | SERUM 25-HYDROXYVITAMIN-D | PREVENTION | RISK | D EXPOSURE | D-RECEPTOR | PLASMA 25-HYDROXYVITAMIN D | Genes | 7-Dehydrocholesterol reductase | Retinoid X receptor α | Hazards | Breast cancer | Single-nucleotide polymorphism | Confidence intervals | Statistical models | Vitamin D | Alleles | Biomarkers | Breast | Vitamin D receptors | Cancer | 25-Hydroxyvitamin D | gene-by-environment interaction | 25-hydroxyvitamin D | single nucleotide polymorphisms | vitamin D
CONSORTIUM | WOMEN | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | VARIANTS | ONCOLOGY | VDR | SERUM 25-HYDROXYVITAMIN-D | PREVENTION | RISK | D EXPOSURE | D-RECEPTOR | PLASMA 25-HYDROXYVITAMIN D | Genes | 7-Dehydrocholesterol reductase | Retinoid X receptor α | Hazards | Breast cancer | Single-nucleotide polymorphism | Confidence intervals | Statistical models | Vitamin D | Alleles | Biomarkers | Breast | Vitamin D receptors | Cancer | 25-Hydroxyvitamin D | gene-by-environment interaction | 25-hydroxyvitamin D | single nucleotide polymorphisms | vitamin D
Journal Article
1989, ISBN 091200634X, xvii, 230 p., 48 p. of plates
Book
Journal of the American Chemical Society, ISSN 0002-7863, 09/2011, Volume 133, Issue 35, pp. 13946 - 13949
The emergence of bacteria resistant to vancomycin, often the antibiotic of last resort, poses a major health problem. Vancomycin-resistant bacteria sense a...
GLYCOPEPTIDE ANTIBIOTICS | TEICOPLANIN AGLYCON | INFECTIONS | CHEMISTRY | BOND ISOSTERES | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | MOLECULES | Peptidoglycan - metabolism | Vancomycin - chemistry | Bacteria - metabolism | Anti-Bacterial Agents - chemistry | Cell Wall - metabolism | Vancomycin Resistance | Anti-Bacterial Agents - metabolism | Dipeptides - metabolism | Vancomycin - metabolism | Binding Sites | Drug resistance in microorganisms | Antimicrobial peptides | Enzyme binding | Chemical properties | Research | Vancomycin | Structure
GLYCOPEPTIDE ANTIBIOTICS | TEICOPLANIN AGLYCON | INFECTIONS | CHEMISTRY | BOND ISOSTERES | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | MOLECULES | Peptidoglycan - metabolism | Vancomycin - chemistry | Bacteria - metabolism | Anti-Bacterial Agents - chemistry | Cell Wall - metabolism | Vancomycin Resistance | Anti-Bacterial Agents - metabolism | Dipeptides - metabolism | Vancomycin - metabolism | Binding Sites | Drug resistance in microorganisms | Antimicrobial peptides | Enzyme binding | Chemical properties | Research | Vancomycin | Structure
Journal Article
Annals of Neurology, ISSN 0364-5134, 01/2007, Volume 61, Issue 1, pp. 25 - 36
Objective To report the autoantigens of a new category of treatment‐responsive paraneoplastic encephalitis. Methods Analysis of clinical features,...
GLUTAMATE-RECEPTOR | ANTIBODIES | SYSTEMIC-LUPUS-ERYTHEMATOSUS | LIMBIC ENCEPHALITIS | ANTI-MA2-ASSOCIATED ENCEPHALITIS | NMDA RECEPTORS | AUTOIMMUNITY | EPILEPSIA PARTIALIS CONTINUA | RAT-BRAIN | EXPRESSION | NEUROSCIENCES | CLINICAL NEUROLOGY | Protein Subunits - immunology | Rats, Wistar | Humans | Immunosuppressive Agents - therapeutic use | Gene Expression Regulation, Neoplastic | Receptors, N-Methyl-D-Aspartate - metabolism | Magnetic Resonance Imaging - methods | Male | Ovarian Neoplasms - complications | Teratoma - metabolism | Transfection - methods | Encephalitis - metabolism | Adult | Female | Ovarian Neoplasms - metabolism | Teratoma - therapy | Neurons - drug effects | Receptors, N-Methyl-D-Aspartate - immunology | Encephalitis - therapy | Dissection - methods | Antibodies - cerebrospinal fluid | Rats | Teratoma - immunology | Encephalitis - immunology | Treatment Outcome | Teratoma - complications | Antibodies - pharmacology | Immunohistochemistry - methods | Animals | Adolescent | Ovarian Neoplasms - therapy | Antibodies - blood | Encephalitis - etiology | Ovarian Neoplasms - immunology
GLUTAMATE-RECEPTOR | ANTIBODIES | SYSTEMIC-LUPUS-ERYTHEMATOSUS | LIMBIC ENCEPHALITIS | ANTI-MA2-ASSOCIATED ENCEPHALITIS | NMDA RECEPTORS | AUTOIMMUNITY | EPILEPSIA PARTIALIS CONTINUA | RAT-BRAIN | EXPRESSION | NEUROSCIENCES | CLINICAL NEUROLOGY | Protein Subunits - immunology | Rats, Wistar | Humans | Immunosuppressive Agents - therapeutic use | Gene Expression Regulation, Neoplastic | Receptors, N-Methyl-D-Aspartate - metabolism | Magnetic Resonance Imaging - methods | Male | Ovarian Neoplasms - complications | Teratoma - metabolism | Transfection - methods | Encephalitis - metabolism | Adult | Female | Ovarian Neoplasms - metabolism | Teratoma - therapy | Neurons - drug effects | Receptors, N-Methyl-D-Aspartate - immunology | Encephalitis - therapy | Dissection - methods | Antibodies - cerebrospinal fluid | Rats | Teratoma - immunology | Encephalitis - immunology | Treatment Outcome | Teratoma - complications | Antibodies - pharmacology | Immunohistochemistry - methods | Animals | Adolescent | Ovarian Neoplasms - therapy | Antibodies - blood | Encephalitis - etiology | Ovarian Neoplasms - immunology
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 01/2012, Volume 134, Issue 2, pp. 1284 - 1297
Journal Article
Journal of High Energy Physics, ISSN 1029-8479, 2018, Volume 2018, Issue 10, pp. 1 - 47
An angular analysis of the decay Bd0 → K∗μ+μ− is presented, based on proton-proton collision data recorded by the ATLAS experiment at the LHC. The study is...
Luminosity | Large Hadron Collider | Particle collisions | Decay | Hadron-Hadron scattering (experiments)
Luminosity | Large Hadron Collider | Particle collisions | Decay | Hadron-Hadron scattering (experiments)
Journal Article
NUCLEAR PHYSICS B, ISSN 0550-3213, 06/2016, Volume 907, pp. 717 - 763
The production of D*(+/-), D-+/- and D-S(+/-) charmed mesons has been measured with the ATLAS detector in pp collisions at,/7s = 7 TeV at the LHC, using data...
QUARK FRAGMENTATION FUNCTION | FRACTIONS | CHARM | MODEL | HADRON-PRODUCTION | E(+)E(-) | DEEP-INELASTIC SCATTERING | PHYSICS, PARTICLES & FIELDS | QUARK FRAGMENTATION FUNCTION; DEEP-INELASTIC SCATTERING; HADRON-PRODUCTION; E(+)E(-) COLLISIONS; JET FRAGMENTATION; HERA; ANNIHILATION; CHARM; MODEL; FRACTIONS | Fysik | Physical Sciences | Naturvetenskap | Natural Sciences
QUARK FRAGMENTATION FUNCTION | FRACTIONS | CHARM | MODEL | HADRON-PRODUCTION | E(+)E(-) | DEEP-INELASTIC SCATTERING | PHYSICS, PARTICLES & FIELDS | QUARK FRAGMENTATION FUNCTION; DEEP-INELASTIC SCATTERING; HADRON-PRODUCTION; E(+)E(-) COLLISIONS; JET FRAGMENTATION; HERA; ANNIHILATION; CHARM; MODEL; FRACTIONS | Fysik | Physical Sciences | Naturvetenskap | Natural Sciences
Journal Article
Developmental Medicine & Child Neurology, ISSN 0012-1622, 07/2017, Volume 59, Issue 7, pp. 719 - 724
Aim To investigate the incidence and severity of anti‐N‐methyl‐d‐aspartate (anti‐NMDA) receptor encephalitis in children from New Zealand. Method A...
PEDIATRICS | EXPERIENCE | SERIES | CLINICAL NEUROLOGY | Severity of Illness Index | Genetic Predisposition to Disease | Humans | Child, Preschool | Infant | Male | Treatment Outcome | Anti-N-Methyl-D-Aspartate Receptor Encephalitis - therapy | Anti-N-Methyl-D-Aspartate Receptor Encephalitis - ethnology | Incidence | Aftercare | Adolescent | Female | Retrospective Studies | Child | New Zealand - epidemiology | Oceanic Ancestry Group | Index Medicus
PEDIATRICS | EXPERIENCE | SERIES | CLINICAL NEUROLOGY | Severity of Illness Index | Genetic Predisposition to Disease | Humans | Child, Preschool | Infant | Male | Treatment Outcome | Anti-N-Methyl-D-Aspartate Receptor Encephalitis - therapy | Anti-N-Methyl-D-Aspartate Receptor Encephalitis - ethnology | Incidence | Aftercare | Adolescent | Female | Retrospective Studies | Child | New Zealand - epidemiology | Oceanic Ancestry Group | Index Medicus
Journal Article
CLINICAL INFECTIOUS DISEASES, ISSN 1058-4838, 03/2014, Volume 58, Issue 5, pp. 622 - 630
Background. The 2012 outbreak of fungal meningitis associated with contaminated methylprednisolone produced by a compounding pharmacy has resulted in >750...
Exserohilum | BETA-GLUCANS | INFECTIOUS DISEASES | CONTAMINATED METHYLPREDNISOLONE INJECTIONS | MICROBIOLOGY | IMMUNOLOGY | CEREBROSPINAL-FLUID | (1-3)-beta-D-glucan | DNA | LEUKEMIA | Fungitell | AID | fungal meningitis | Humans | Middle Aged | beta-Glucans - cerebrospinal fluid | Male | Drug Monitoring - methods | Clinical Laboratory Techniques - methods | Disease Outbreaks | Diagnostic Tests, Routine - methods | Sensitivity and Specificity | Adolescent | Aged, 80 and over | Adult | Female | Aged | Meningitis, Fungal - diagnosis | Meningitis, Fungal - epidemiology | Care and treatment | Medical examination | Cerebrospinal fluid | Fungal meningitis | Diagnosis | and Commentaries | (1-3)-β-d-glucan
Exserohilum | BETA-GLUCANS | INFECTIOUS DISEASES | CONTAMINATED METHYLPREDNISOLONE INJECTIONS | MICROBIOLOGY | IMMUNOLOGY | CEREBROSPINAL-FLUID | (1-3)-beta-D-glucan | DNA | LEUKEMIA | Fungitell | AID | fungal meningitis | Humans | Middle Aged | beta-Glucans - cerebrospinal fluid | Male | Drug Monitoring - methods | Clinical Laboratory Techniques - methods | Disease Outbreaks | Diagnostic Tests, Routine - methods | Sensitivity and Specificity | Adolescent | Aged, 80 and over | Adult | Female | Aged | Meningitis, Fungal - diagnosis | Meningitis, Fungal - epidemiology | Care and treatment | Medical examination | Cerebrospinal fluid | Fungal meningitis | Diagnosis | and Commentaries | (1-3)-β-d-glucan
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2006, Volume 128, Issue 9, pp. 2885 - 2892
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 03/2006, Volume 128, Issue 9, pp. 2885 - 2892
An effective synthesis of [Ψ[CH2NH]Tpg4]vancomycin aglycon (5) is detailed in which the residue 4 amide carbonyl of vancomycin aglycon has been replaced with a...
Alanine - analogs & derivatives | Lactates - metabolism | Vancomycin - chemical synthesis | Vancomycin - analogs & derivatives | Alanine - chemistry | Dipeptides - metabolism | Kinetics | Oligopeptides - metabolism | Vancomycin - metabolism | Dipeptides - chemistry | Oligopeptides - chemistry | Lactates - chemistry
Alanine - analogs & derivatives | Lactates - metabolism | Vancomycin - chemical synthesis | Vancomycin - analogs & derivatives | Alanine - chemistry | Dipeptides - metabolism | Kinetics | Oligopeptides - metabolism | Vancomycin - metabolism | Dipeptides - chemistry | Oligopeptides - chemistry | Lactates - chemistry
Journal Article
Monthly Notices of the Royal Astronomical Society, ISSN 0035-8711, 08/2015, Volume 453, Issue 2, pp. 1324 - 1343
STARBENCH is a project focused on benchmarking and validating different star formation and stellar feedback codes. In this first STARBENCH paper we perform a...
Hydrodynamics | ISM: bubbles | HII regions | Galaxies: ISM | ISM: kinematics and dynamics | Methods: numerical | DRIVEN IMPLOSION | MASSIVE STARS | PROTOSTELLAR DISKS | INTERSTELLAR GAS LAYERS | ADAPTIVE MESH REFINEMENT | hydrodynamics | methods: numerical | SMOOTHED PARTICLE HYDRODYNAMICS | TRIGGERED STAR-FORMATION | COSMOLOGICAL RADIATIVE-TRANSFER | H II regions | TURBULENT MOLECULAR CLOUDS | galaxies: ISM | ASTRONOMY & ASTROPHYSICS | IONIZING-RADIATION | Mechanics | Mechanics of the fluids | Solar and Stellar Astrophysics | Earth and Planetary Astrophysics | Astrophysics | Physics
Hydrodynamics | ISM: bubbles | HII regions | Galaxies: ISM | ISM: kinematics and dynamics | Methods: numerical | DRIVEN IMPLOSION | MASSIVE STARS | PROTOSTELLAR DISKS | INTERSTELLAR GAS LAYERS | ADAPTIVE MESH REFINEMENT | hydrodynamics | methods: numerical | SMOOTHED PARTICLE HYDRODYNAMICS | TRIGGERED STAR-FORMATION | COSMOLOGICAL RADIATIVE-TRANSFER | H II regions | TURBULENT MOLECULAR CLOUDS | galaxies: ISM | ASTRONOMY & ASTROPHYSICS | IONIZING-RADIATION | Mechanics | Mechanics of the fluids | Solar and Stellar Astrophysics | Earth and Planetary Astrophysics | Astrophysics | Physics
Journal Article