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Seminars in cell & developmental biology, ISSN 1084-9521, 05/2019
Succinate dehydrogenase (SDH) has been classically considered a mitochondrial enzyme with the unique property to participate in both the citric acid cycle and... 
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 11/2013, Volume 85, Issue 3, pp. 373 - 380
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 12/2017, Volume 113, pp. 176 - 189
Several studies indicate that mitochondrial uncoupling protein 2 (UCP2) plays a pivotal role in cancer development by decreasing reactive oxygen species (ROS)... 
Uncoupling proteins | Cell death | Pancreas cancer | UCP2 | mTOR | Everolimus | GAPDH | PANCREATIC DUCTAL ADENOCARCINOMA | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EARLY SECRETORY PATHWAY | MULTIMODAL TREATMENT | CANCER | CELL-DEATH | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE | ENDOCRINOLOGY & METABOLISM | STRESS | MITOCHONDRIAL UNCOUPLING PROTEIN-2 | Uncoupling Protein 2 - antagonists & inhibitors | Pancreatic Neoplasms - metabolism | Reactive Oxygen Species - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Carcinoma, Pancreatic Ductal - metabolism | Male | Antineoplastic Agents - therapeutic use | Pancreatic Neoplasms - drug therapy | TOR Serine-Threonine Kinases - antagonists & inhibitors | Everolimus - therapeutic use | Female | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Everolimus - pharmacology | Signal Transduction | Uncoupling Protein 2 - metabolism | Pancreatic Neoplasms - enzymology | Protein Transport | Carcinoma, Pancreatic Ductal - enzymology | Xenograft Model Antitumor Assays | Carcinoma, Pancreatic Ductal - drug therapy | Iridoids - pharmacology | Cell Line, Tumor | Carcinoma, Pancreatic Ductal - physiopathology | Cell Proliferation - drug effects | Iridoids - therapeutic use | Glyceraldehyde-3-Phosphate Dehydrogenases - metabolism | Pancreatic Neoplasms - physiopathology | Apoptosis | Phosphates | Enzymes | Care and treatment | Pancreatic cancer | Physiological aspects | Development and progression | Drug therapy, Combination | Cancer | Index Medicus
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 03/2013, Volume 1833, Issue 3, pp. 672 - 679
Mitochondrial uncoupling protein 2 (UCP2) can moderate oxidative stress by favoring the influx of protons into the mitochondrial matrix, thus reducing electron... 
Autophagy | GAPDH | UCP2 | ROS | Cancer | Genipin | CANCER-CELLS | APOPTOSIS | OXIDATIVE STRESS | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | H2O2 | GEMCITABINE | CELL BIOLOGY | CROSS-TALK | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE | RESISTANCE | MITOCHONDRIAL UNCOUPLING PROTEIN-2 | Adenocarcinoma | Chemotherapy | Cell death | Pancreatic cancer | Development and progression | Biochemistry | Superoxide
Journal Article
IUBMB Life, ISSN 1521-6543, 09/2015, Volume 67, Issue 9, pp. 687 - 693
Journal Article
Journal of Proteomics, ISSN 1874-3919, 01/2017, Volume 150, pp. 310 - 322
Recently, we have shown that the secretome of pancreatic cancer stem cells (CSCs) is characterized by proteins that participate in cancer differentiation,... 
Cancer stem cells | Pancreatic cancer | Pancreatic ductal adenocarcinoma PDAC | GLYCOLYSIS | METASTASIS | INHIBITION | GROWTH | BIOCHEMICAL RESEARCH METHODS | UP-REGULATION | CARCINOMA | Proteins | Phosphates | Glucose metabolism | Synthesis | Analysis | Stem cells | Physiological aspects | Fatty acids | Metabolites | Sugars | Monosaccharides
Journal Article
BBA - General Subjects, ISSN 0304-4165, 01/2019, Volume 1863, Issue 1, pp. 61 - 72
Journal Article