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Pharmacological Research, ISSN 1043-6618, 10/2018, Volume 136, pp. 140 - 150
Journal Article
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 10/2013, Volume 5, Issue 10, pp. 1569 - 1585
Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in breaches of the plasma membrane and chronic inflammation in Duchenne... 
mdx | anti‐inflammatory | membrane injury | dystrophy | muscle | Muscle | Dystrophy | Membrane injury | Anti-inflammatory | MEDICINE, RESEARCH & EXPERIMENTAL | DNA-BINDING | OXIDATIVE STRESS | UTROPHIN | MOUSE | DEFICIENT MDX MICE | SKELETAL-MUSCLE | GLUCOCORTICOID-RECEPTOR | SEALANT POLOXAMER | anti-inflammatory | GENE-EXPRESSION | NF-KAPPA-B | Transcription, Genetic - drug effects | Prednisolone - toxicity | Protein Interaction Maps - drug effects | NF-kappa B - metabolism | Pregnadienediols - toxicity | Receptors, Glucocorticoid - metabolism | Cell Membrane - physiology | Myoblasts - drug effects | Lasers | T-Lymphocytes - drug effects | Mice, Inbred mdx | Myoblasts - cytology | Immunosuppressive Agents - pharmacology | Cell Membrane - drug effects | Cell Line | NF-kappa B - antagonists & inhibitors | Muscular Dystrophies - metabolism | Anti-Inflammatory Agents - pharmacology | Anti-Inflammatory Agents - toxicity | Immunosuppressive Agents - toxicity | Muscular Dystrophies - pathology | Myoblasts - radiation effects | Prednisolone - pharmacology | Pregnadienediols - pharmacology | Phenotype | Animals | Signal Transduction - drug effects | Necrosis - etiology | Receptors, Glucocorticoid - genetics | T-Lymphocytes - immunology | Mice | Corticosteroids | Immunotherapy | Utrophin | Muscles | Dystrophin | Prednisolone | Muscular dystrophy | Glucocorticoids | Transcription | Laboratories | Funding | Menopause | Experiments | Inflammatory diseases | Immunology | Duchenne's muscular dystrophy | Muscular strength | Pharmaceutical sciences | Data analysis | Automation | Oral administration | Histology | Inflammation | Grants | Skeletal muscle | Immunosuppression | Side effects | Protein interaction
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e63871
Asthma is a chronic inflammatory condition of the lower respiratory tract associated with airway hyperreactivity and mucus obstruction in which a majority of... 
PROMOTER ACTIVITY | RESPONSES | DNA-BINDING | EPITHELIUM | MULTIDISCIPLINARY SCIENCES | MAST-CELLS | INHALED CORTICOSTEROIDS | ASTHMA | RECEPTOR | MECHANISMS | INTERLEUKIN-10 | Asthma - metabolism | Glucocorticoids - therapeutic use | Epithelial Cells - drug effects | Humans | Male | NF-kappa B - metabolism | Hypersensitivity - complications | Leukocytes - physiology | Hypersensitivity - drug therapy | Tibia - pathology | Epithelial Cells - secretion | Female | Disease Models, Animal | Ovalbumin | Lung - pathology | Osteogenesis - drug effects | Cytokines - secretion | Epithelial Cells - pathology | Tibia - drug effects | Cell Movement - drug effects | Pregnadienediols - pharmacology | Animals | Pneumonia - drug therapy | Asthma - complications | Lung - drug effects | Pregnadienediols - therapeutic use | Glucocorticoids - chemistry | Glucocorticoids - pharmacology | Pneumonia - complications | Leukocytes - drug effects | Mice | Mice, Inbred BALB C | Asthma - pathology | Pregnadienediols - chemistry | Cell Degranulation - drug effects | Allergens | Corticosteroids | Analysis | Respiratory agents | Inflammation | Genetic aspects | Prednisone | Prednisolone | Asthma | Steroids | Health sciences | Glucocorticoids | Transcription | Physicians | Epithelial cells | Mucus | Biology | Inflammatory diseases | Respiratory tract | Proteins | Immunology | Tibia | Rodents | Antiinflammatory agents | Cytokines | Hypersensitivity | Medical treatment | Gene expression | Allergies | Children & youth | White blood cells | Medicine | Side effects | Lungs | Degranulation | Ligands | Health risk assessment
Journal Article
Journal Article
Journal Article
Steroids, ISSN 0039-128X, 06/2018, Volume 134, pp. 43 - 52
•Vamorolone (VBP15) is a steroidal drug that has shown dissociative properties.•The X-ray crystal structure of vamorolone is presented.•In a Phase 1 clinical... 
AIRWAY EPITHELIAL-CELLS | SYSTEM | VBP15 | GLUCOCORTICOIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | MECHANISMS | Complications and side effects | Patient outcomes | Crystals | Clinical trials | Insulin resistance | Structure | Biological markers
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 08/2016, Volume 6, Issue 1, p. 31727
Journal Article