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American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 09/2018, Volume 198, Issue 5, pp. 549 - 551
An exciting aspect of this work is the linking of matrix stiffness to epithelial gene regulation through an epigenetic mechanism, one that places the... 
FIBROSIS | LUNG | RESPIRATORY SYSTEM | CRITICAL CARE MEDICINE | Studies | CRISPR | Transcription factors | Pulmonary fibrosis | DNA methylation | Epigenetics | Editing | Genomes | Gene expression | Deoxyribonucleic acid--DNA
Journal Article
Thorax, ISSN 0040-6376, 2019, Volume 74, Issue 8, pp. 749 - 760
Idiopathic pulmonary fibrosis (IPF) is a fatal ageing-related disease linked to mitochondrial dysfunction. The present study aimed to determine whether... 
interstitial fibrosis | idiopathic pulmonary fibrosis | MITOCHONDRIAL DYSFUNCTION | LUNG FIBROBLASTS | IDIOPATHIC PULMONARY-FIBROSIS | RESPIRATORY SYSTEM | CELLULAR SENESCENCE | PGC-1-ALPHA | Interstitial Lung Disease | 2313 | 1506
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 03/2019, Volume 316, Issue 3, pp. L487 - L497
Journal Article
Annals of the American Thoracic Society, ISSN 2325-6621, 03/2015, Volume 12, pp. S24 - S29
The extracellular matrix (ECM) of the lung serves as both a scaffold for resident cells and a mechanical support for respiratory function. The ECM is deposited... 
Extracellular matrix | Fibroblast | Lung | Fibrosis | Mesoderm - physiology | Fibroblasts - cytology | Pulmonary Fibrosis - metabolism | Mechanotransduction, Cellular - physiology | Extracellular Matrix - physiology | Humans
Journal Article
Physiology, ISSN 1548-9213, 11/2013, Volume 28, Issue 6, pp. 380 - 390
Journal Article
American Journal of Physiology, ISSN 1040-0605, 06/2018, Volume 314, Issue 6, p. L946
Lung function is inherently mechanical in nature and depends on the capacity to conduct air and blood to and from the gas exchange regions. Variations in the... 
Atomic force microscopy | Respiratory function | Smooth muscle | Risk factors | Compartments | Aging | Extracellular matrix | Stiffness | Elastic properties | Trends | Age | Lung diseases | Muscles | Mechanical properties | Blood vessels | Modulus of elasticity | Stiffening | Microhardness | Cells | Pulmonary artery | Studies | Microscopy | Lungs | Gas exchange | Variation
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 2000, Volume 162, Issue 2 I, pp. 357 - 362
Journal Article
American Journal of Physiology, ISSN 1040-0605, 10/2015, Volume 309, Issue 7, p. L625
  Lung diseases such as emphysema, interstitial fibrosis, and pulmonary vascular diseases cause significant morbidity and mortality, but despite substantial... 
Bioengineering | Transplants & implants | Lung diseases | Extracellular matrix | Biocompatibility | Physiology
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2018, Volume 128, Issue 1, pp. 74 - 84
Journal Article
Journal Article
Matrix Biology, ISSN 0945-053X, 11/2018, Volume 73, pp. 64 - 76
Journal Article
American Journal of Physiology, ISSN 1040-0605, 06/2015, Volume 308, Issue 11, p. L1125
  Multiple pulmonary conditions are characterized by an abnormal misbalance between various tissue components, for example, an increase in the fibrous... 
Tissue | Lungs | Kinases | Gene expression | Cells
Journal Article