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Pflügers Archiv - European Journal of Physiology, ISSN 0031-6768, 1/2011, Volume 461, Issue 1, pp. 1 - 21
Ion channels and transporters play a critical role in ion and fluid homeostasis and thus in normal animal physiology and pathology. Tight regulation of these... 
Signal transduction | Biomedicine | Sodium channel | Human Physiology | Electrophysiology | Anion channel | Cation channel | Aldosterone | Cystic fibrosis transmembrane conductance regulator | Ion channel | Epithelial Na channels | Potassium channel | PHYSIOLOGY | PROTEIN LIGASE NEDD4 | RETICULUM-ASSOCIATED DEGRADATION | CELL-SURFACE EXPRESSION | EPITHELIAL SODIUM-CHANNEL | INDUCIBLE KINASE SGK | TRANSMEMBRANE CONDUCTANCE REGULATOR | NA+ CHANNEL | INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS | LIDDLES-SYNDROME | ENDOPLASMIC-RETICULUM | Potassium Channels, Voltage-Gated - physiology | Immediate-Early Proteins - physiology | Protein-Serine-Threonine Kinases - physiology | Humans | Aldosterone - physiology | Endoplasmic Reticulum - physiology | Cystic Fibrosis Transmembrane Conductance Regulator - physiology | Sodium Channels - physiology | Epithelial Sodium Channels - metabolism | Ubiquitin-Protein Ligases - physiology | Ubiquitin - physiology | Endocytosis - physiology | Small Ubiquitin-Related Modifier Proteins - physiology | Calcium Channels - physiology | Animals | Nedd4 Ubiquitin Protein Ligases | Membrane Proteins - metabolism | Ubiquitination - physiology | Vasopressins - physiology | Ion Transport - physiology | Endosomal Sorting Complexes Required for Transport - physiology | Chloride Channels - physiology | Ubiquitin | Corticosteroids | Ligases | Children's hospitals | Physiological aspects | Cystic fibrosis | Membrane proteins
Journal Article
Nature Communications, ISSN 2041-1723, 05/2015, Volume 6, Issue 1, p. 7250
Mammalian target of rapamycin 1 (mTORC1), a master regulator of cellular growth, is activated downstream of growth factors, energy signalling and intracellular... 
HEPATOCELLULAR-CARCINOMA | AMINO-ACIDS | MULTIDISCIPLINARY SCIENCES | GROWTH | RESISTANCE | TARGETS | MECHANISMS | CANCER
Journal Article
Nature Cell Biology, ISSN 1465-7392, 10/2014, Volume 16, Issue 12, pp. 1227 - 1237
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, p. e27478
Journal Article
Science, ISSN 0036-8075, 2/2013, Volume 339, Issue 6119, pp. 590 - 595
Journal Article
Nature Cell Biology, ISSN 1465-7392, 04/2013, Volume 15, Issue 4, pp. 430 - 439
Polo-like kinase 1 (PLK1) critically regulates mitosis through its dynamic localization to kinetochores, centrosomes and the midzone. The polo-box domain (PBD)... 
E3 LIGASE | CELL-DIVISION | COMPLEX | POLO-BOX DOMAIN | KINASE-1 | POLO-LIKE-KINASE-1 | ROLES | RING UBIQUITIN LIGASES | SPINDLE-ASSEMBLY CHECKPOINT | AURORA-B | CELL BIOLOGY | RNA, Small Interfering - genetics | Phosphorylation | Immunoprecipitation | Humans | Ubiquitin - metabolism | Molecular Sequence Data | Cell Cycle Proteins - antagonists & inhibitors | Microtubules - metabolism | Ubiquitination | Spindle Apparatus - metabolism | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Cullin Proteins - metabolism | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Proto-Oncogene Proteins - antagonists & inhibitors | Cullin Proteins - antagonists & inhibitors | Kinetochores - metabolism | Signal Transduction | Chromosomes, Human - genetics | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Blotting, Western | Centrosome - metabolism | Cullin Proteins - genetics | Sequence Homology, Amino Acid | Mitosis - physiology | Adaptor Proteins, Signal Transducing - genetics | Protein Array Analysis | HeLa Cells | Adaptor Proteins, Signal Transducing - metabolism | Microscopy, Fluorescence | Physiological aspects | Research | Ubiquitin-proteasome system | Mitosis | Protein kinases
Journal Article