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PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e33232
The effect of microgravity on skeletal muscles has so far been examined in rat and mice only after short-term (5-20 day) spaceflights. The mice drawer system... 
RAT SOLEUS MUSCLE | HEAT-STRESS | HINDLIMB SUSPENSION | NITRIC-OXIDE SYNTHASE | BIOLOGY | GENE-EXPRESSION | FAST-TWITCH MUSCLES | MYONUCLEAR NUMBER | BED REST | FIBER SIZE | TRANSGENIC MICE | Adaptation, Physiological | Immunohistochemistry | Up-Regulation | Down-Regulation | Mice, Inbred C57BL | Ubiquitin-Protein Ligases - metabolism | Rats | Male | Muscle, Skeletal - metabolism | Weightlessness | Space Flight | Myosin Heavy Chains - metabolism | Animals | Nitric Oxide Synthase Type I - metabolism | Potassium Channels, Calcium-Activated - metabolism | Mice | Interleukin-6 - metabolism | Insulin-Like Growth Factor I - metabolism | Ligases | Genes | Nitric oxide | Myosin | Muscles | Muscle proteins | Gene expression | Space stations | Ubiquitin | Brain | Health sciences | Neurosciences | Insulin-like growth factor I | Interleukin | Insulin-like growth factors | Soleus muscle | Cytosol | Autophagy | Potassium channels (calcium-gated) | Posture | Interleukin 6 | Atrophy | Genotype & phenotype | Osteoporosis | Embryology | Rodents | Physiology | Ion channels | Microgravity | Adaptation | Translocation | Calcium channels | Histology | Pharmacology | Space flight | Anatomy & physiology | Nitric-oxide synthase | Skeletal muscle | Medicine | Studies | Musculoskeletal system | International Space Station | Antigravity | Astronauts | Phagocytosis
Journal Article
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 2017, Volume 313, Issue 1, pp. C54 - C67
We investigated the effects of S1P3 deficiency on the age-related atrophy, decline in force, and regenerative capacity of soleus muscle from 23-mo-old male... 
Aging | Regeneration | Sarcopenia | S1P | receptor | Soleus muscle
Journal Article
American Journal of Physiology, ISSN 0363-6143, 07/2017, Volume 313, Issue 1, p. C54
We investigated the effects of S1P3 deficiency on the age-related atrophy, decline in force, and regenerative capacity of soleus muscle from 23-mo-old male... 
Studies | Atrophy | Tissue engineering | Contractility | Aging | Muscular system | Soleus muscle | Muscle contraction | Impact analysis
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 09/2012, Volume 113, Issue 5, pp. 707 - 713
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 03/2010, Volume 298, Issue 3, pp. 550 - 558
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e65167
Slow-twitch muscles, devoted to postural maintenance, experience atrophy and weakness during muscle disuse due to bed-rest, aging or spaceflight. These... 
HYPERTROPHY | ACTIVATION | PROTEIN | ATROPHY | REGENERATION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | SOLEUS | EXERCISE | GROWTH-FACTOR-I | CHANNEL REGULATION | Body Weight | Calcium - metabolism | Humans | Muscle Fibers, Fast-Twitch - metabolism | Muscular Atrophy - pathology | Gene Expression Regulation | Rats | Mice, Transgenic | Muscle Fibers, Slow-Twitch - metabolism | Behavior, Animal | Chloride Channels - metabolism | Hindlimb - physiopathology | Rest | Animals | Muscle Contraction | Muscular Atrophy - physiopathology | Muscle, Skeletal - physiopathology | Paracrine Communication - drug effects | Cytosol - metabolism | Weight-Bearing | Biochemical Phenomena | Myosin Light Chains - metabolism | Muscle, Skeletal - pathology | Insulin-Like Growth Factor I - metabolism | Physiological aspects | Muscles | Genetic aspects | Research | Muscle proteins | Gene expression | Insulin-like growth factor 1 | Histone deacetylase | Transcription | Insulin-like growth factor I | Paracrine signalling | Insulin-like growth factors | Kinases | Soleus muscle | Phosphatase | Posture | Proteins | Atrophy | Genotype & phenotype | Embryology | Parameter modification | Chloride conductance | Chlorides | Rodents | Myosin | Aging | Neuromuscular diseases | Human motion | Contractility | Transgenic mice | Unloading | Histology | Pharmacology | Space flight | Metabolism | Muscle contraction | Skeletal muscle | Resistance | Studies | Musculoskeletal system | Pharmacy | Weight reduction | Muscle function | Conductance | Mice | Life Sciences | Biochemistry, Molecular Biology
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 06/2016, Volume 120, Issue 11, p. 1288
  To examine the role of sphingosine 1-phosphate (S1P) receptor 3 (S1P^sub 3^) in modulating muscle properties, we utilized transgenic mice depleted of the... 
Rodents | Protein expression | Muscular system | Gene expression
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 06/2016, Volume 120, Issue 11, pp. 1288 - 1288
To examine the role of sphingosine 1-phosphate (S1P) receptor 3 (S1P sub( 3)) in modulating muscle properties, we utilized transgenic mice depleted of the... 
Journal Article
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 09/2012, Volume 113, Issue 5, pp. 707 - 713
Journal Article
Journal Article
American Journal of Physiology, ISSN 0363-6119, 01/2014, Volume 306, Issue 2, p. R124
  Facioscapulohumeral muscular dystrophy (FSHD), a common hereditary myopathy, is characterized by atrophy and weakness of selective muscle groups. FSHD is... 
Calcium | Correlation analysis | Rodents | Muscular system | Muscular dystrophy
Journal Article
American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, ISSN 0363-6119, 01/2014, Volume 306, Issue 2, pp. R124 - R124
Facioscapulohumeral muscular dystrophy (FSHD), a common hereditary myopathy, is characterized by atrophy and weakness of selective muscle groups. FSHD is... 
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e72028
Pleiotrophin (PTN) is a widespread cytokine involved in bone formation, neurite outgrowth, and angiogenesis. In skeletal muscle, PTN is upregulated during... 
TRANSCRIPTIONAL COACTIVATOR PGC-1-ALPHA | AFFIN REGULATORY PEPTIDE | INDUCED ANGIOGENESIS | DIVERSE FUNCTIONS | MULTIDISCIPLINARY SCIENCES | SOLEUS MUSCLE | K-ATP CHANNEL | MICE | DISUSE | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Calcium - metabolism | Humans | Ion Channels - genetics | Muscle, Skeletal - metabolism | Electron Transport Complex IV - metabolism | Muscle Proteins - metabolism | Citrate (si)-Synthase - metabolism | Cytokines - genetics | Sarcolemma - metabolism | Gene Expression | Cytokines - metabolism | Muscular Atrophy - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Electron Transport Complex IV - genetics | Hindlimb Suspension | Space Flight | Muscle Proteins - genetics | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Ion Channels - metabolism | Muscle Fibers, Skeletal | Citrate (si)-Synthase - genetics | Mice | Muscle, Skeletal - pathology | Muscles | Gene expression | Cytochrome | Calcium | Oxidative metabolism | Cytochrome-c oxidase | Oncology | Biology | Parameter sensitivity | Soleus muscle | Experiments | Fibers | Atrophy | Angiogenesis | Osteoporosis | Bone growth | Transgenic animals | Loading | Rodents | Bones | Ion channels | Vascular endothelial growth factor | Microgravity | Sarcolemma | Gravitation | Axonogenesis | Pleiotrophin | Unloading | Blood vessels | Pharmacology | Space flight | Metabolism | Skeletal muscle | Myogenesis | Regeneration | Musculoskeletal system | Pharmacy | Muscle function | Bone | Osteogenesis
Journal Article