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Science, ISSN 0036-8075, 8/2004, Volume 305, Issue 5687, pp. 1163 - 1167
Gefitinib (Iressa, AstraZeneca Pharmaceuticals) is a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR) and induces dramatic... 
Phosphorylation | Receptors | Cell lines | Small interfering RNA | Antibodies | Immunoblotting | Reports | Viability | Lung neoplasms | Tumors | Apoptosis | TRIAL | GROWTH-FACTOR RECEPTOR | THERAPY | RAS/RAF/MEK/ERK PATHWAY | TYROSINE KINASE | MULTIDISCIPLINARY SCIENCES | CELL-CYCLE PROGRESSION | INHIBITOR | ZD1839 | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Sequence Deletion | Humans | Lung Neoplasms - pathology | Mutation, Missense | DNA-Binding Proteins - metabolism | Receptor, Epidermal Growth Factor - metabolism | Transfection | Milk Proteins | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Cell Line | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Cell Survival | Proto-Oncogene Proteins c-akt | Tyrosine - metabolism | Animals | STAT5 Transcription Factor | Cell Line, Tumor | Trans-Activators - metabolism | Mice | RNA, Small Interfering | Carcinoma, Non-Small-Cell Lung - drug therapy | Enzyme Activation | Mutation | Trans-Activators - antagonists & inhibitors | Quinazolines - pharmacology | Mitogen-Activated Protein Kinases - metabolism | Protein tyrosine kinase | Physiological aspects | Genetic aspects | Research | Drug therapy | Lung cancer | Enzymes
Journal Article
Clinical Chemistry, ISSN 0009-9147, 01/2014, Volume 60, Issue 1, pp. 98 - 110
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2008, Volume 359, Issue 4, pp. 366 - 377
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 11/2018, Volume 57, Issue 11, pp. 1445 - 1457
Serous endometrial cancers (ECs) are clinically aggressive tumors that frequently harbor somatic mutations in FBXW7 (F‐box and WD repeat domain‐containing 7).... 
ARK1 | SRC‐3 | uterine cancer | Cyclin E1 | ARK2 | SRC-3 | CYCLIN-E | UBIQUITIN LIGASE | PROGNOSIS | UTERUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | UTERINE CARCINOSARCOMAS | PATTERNS | MIXED MULLERIAN TUMORS | ONCOLOGY | RECEPTOR COREGULATORS | RICTOR | CLEAR-CELL CARCINOMA | RNA, Small Interfering - genetics | Phosphorylation | Humans | Cystadenocarcinoma, Serous - metabolism | Endometrial Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | Cystadenocarcinoma, Serous - genetics | Cystadenocarcinoma, Serous - pathology | Biomarkers, Tumor | Cystadenocarcinoma, Serous - drug therapy | Gene Editing | F-Box-WD Repeat-Containing Protein 7 - genetics | Endometrial Neoplasms - genetics | Biomarkers | Cell Line, Tumor | Endometrial Neoplasms - drug therapy | Endometrial Neoplasms - pathology | Female | Mutation | F-Box-WD Repeat-Containing Protein 7 - metabolism | Synthesis | Endometrial cancer | Ligases | Glycogen | Analysis | Genetic aspects | Protein kinases | Cancer | Ubiquitin | AKT protein | Myc protein | Kinases | Cdc4 protein | Cullin | Proteins | Transfection | Tumorigenesis | Endometrium | Ubiquitin-protein ligase | CRISPR | Glycogen synthase kinase 3 | Src protein | Substrates | Ribosomal protein S6 kinase | Sensitivity | Inhibitors | Cell lines | Tumor suppressor genes | Tumors
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