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Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 10/2015, Volume 76, Issue 4, pp. 853 - 864
Multidrug efflux pumps such as ABCG2 confer drug resistance to a number of cancer types, leading to poor prognosis and outcome. To date, the strategy of... 
BCRP | Cancer chemotherapy | Medicine & Public Health | Multidrug resistance | Oncology | Cancer Research | Pim1 kinase | Pharmacology/Toxicology | ABCG2 | PROTEIN-KINASE | CELL-SURFACE EXPRESSION | STRUCTURAL-ANALYSIS | PLASMA-MEMBRANE | BREAST-CANCER CELLS | IN-VITRO | SUBSTRATE-SPECIFICITY | ONCOLOGY | PROSTATE-CANCER | PHARMACOLOGY & PHARMACY | HUMAN MULTIDRUG TRANSPORTER | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Drugs, Investigational - pharmacology | Drug Resistance, Multiple | Humans | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Protein Transport - drug effects | Pyridazines - pharmacology | Neoplasm Proteins - metabolism | Antineoplastic Agents - metabolism | ATP-Binding Cassette Transporters - genetics | Proto-Oncogene Proteins c-pim-1 - antagonists & inhibitors | ATP-Binding Cassette Transporters - metabolism | Inhibitory Concentration 50 | Antineoplastic Agents - pharmacology | Biological Transport - drug effects | Neoplasm Proteins - genetics | Recombinant Proteins - metabolism | Cell Survival - drug effects | Recombinant Proteins - chemistry | Imidazoles - pharmacology | Down-Regulation - drug effects | Drug Synergism | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Kinetics | ATP-Binding Cassette Transporters - antagonists & inhibitors | Proteins | Drug resistance | Anthracyclines | Index Medicus
Journal Article
Microbial Cell Factories, ISSN 1475-2859, 03/2017, Volume 16, Issue 1, pp. 41 - 41
Background: We previously selected four strains of Saccharomyces cerevisiae for their ability to produce the aquaporin Fps1 in sufficient yield for further... 
Leaky scanning | Translation initiation | Upstream open reading frame | Fps1 regulation | Recombinant protein | Aquaglyceroporin | Saccharomyces cerevisiae | DOMAIN | GCN4 | ESCHERICHIA-COLI | GLYCEROL CHANNEL FPS1P | SACCHAROMYCES-CEREVISIAE | PROTEIN-SYNTHESIS | GENOME | ARSENITE | BIOGENESIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EXPRESSION | Gene Expression Regulation, Fungal | Peptide Chain Initiation, Translational - genetics | Saccharomyces cerevisiae - genetics | Open Reading Frames | Saccharomyces cerevisiae - drug effects | Green Fluorescent Proteins - genetics | Recombinant Proteins - biosynthesis | Saccharomyces cerevisiae Proteins - genetics | Aquaporin 1 - genetics | 5' Untranslated Regions | Receptor, Adenosine A2A - biosynthesis | Aquaporin 1 - biosynthesis | Plasmids - genetics | Doxycycline - pharmacology | Genes, Fungal | Receptor, Adenosine A2A - genetics | Polyribosomes | Codon, Terminator | Fidelity | Cell culture | Regulations | Phosphorylation | Yeast | Transcription | Peptides | Gene regulation | Escherichia coli | Antibodies | Amino acids | Biosynthesis | Genomes | Proteins | Mating | Clonal deletion | Energy conservation | Topography | Down-regulation | Cap-binding protein | Peroxidase | Adenosine | Starvation | Aquaporins | Base pairs | Glycerol | Osmoregulation | Cultures | Protein biosynthesis | Gene expression | Stress | Membrane proteins | Strain | Molecular modelling | Acids | Bioreactors | Protein synthesis | Doxycycline | Green fluorescent protein | Yield | Acetic acid | Arsenite | Heat shock | Index Medicus | Biological Sciences | Biologiska vetenskaper
Journal Article
Microbial Cell Factories, ISSN 1475-2859, 01/2009, Volume 8, Issue 1, pp. 10 - 10
Background: The production of high yields of recombinant proteins is an enduring bottleneck in the post-genomic sciences that has yet to be addressed in a... 
HEAT | BIOGENESIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESCHERICHIA-COLI | GROWTH | COUPLED RECEPTORS | OPTIMIZATION | REGULATORY DOMAIN | BINDING PROTEIN | SACCHAROMYCES-CEREVISIAE | EXPRESSION | Usage | Yeast fungi | Ribosomes | Microbiological synthesis | Physiological aspects | Genetic aspects | Research | Recombinant proteins | Methods | Production processes
Journal Article
Microbial Cell Factories, ISSN 1475-2859, 06/2010, Volume 9, Issue 1, pp. 47 - 47
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2012, Volume 866, pp. 181 - 190
A common method for inducing the production of recombinant proteins in Pichia pastoris is through the use of methanol. However, the by-products of methanol... 
Mixed feeds | Yeast | Optimisation | Methanol | Methanol - metabolism | Recombinant Proteins - metabolism | Pichia - metabolism | Pichia - drug effects | Bioreactors - microbiology | Pichia - genetics | Recombinant Proteins - genetics | Fermentation | Methanol - adverse effects | Pichia - growth & development | Index Medicus
Conference Proceeding
Methods in Molecular Biology, ISSN 1064-3745, 2012, Volume 866, pp. 237 - 246
Yeast is a proven host for the production of recombinant proteins, which may be incorporated in cellular membranes or localized in subcellular compartments. In... 
Homogenization | Disruption | FastPrep | Emulsiflex C3 | French press | Recombinant Proteins - isolation & purification | Biotechnology - methods | Yeasts - genetics | Recombinant Proteins - genetics | Recombinant Proteins - biosynthesis | Yeasts - metabolism | Index Medicus
Conference Proceeding
Methods in Molecular Biology, ISSN 1064-3745, 2012, Volume 866, pp. 57 - 63
There are several ways to introduce non-native DNA into yeast cells, including chemical transformation and electroporation. Methods for both of these... 
Electroporation | Competent cells | Pichia pastoris | Saccharomyces cerevisiae | Saccharomyces cerevisiae - metabolism | Transformation, Genetic - genetics | Pichia - metabolism | Saccharomyces cerevisiae - genetics | Pichia - genetics | Index Medicus
Conference Proceeding
Biotechnology and Bioengineering, ISSN 0006-3592, 12/2007, Volume 98, Issue 5, pp. 1103 - 1108
We have shown previously that a sequence-specific DNA-binding protein based on the Lac repressor protein can isolate pre-purified DNA efficiently from simple... 
LacO-LacI binding | Protein-DNA interaction | Plasmid DNA | Affinity chromatography | Affinity ligands | affinity chromatography | RNA | protein-DNA interaction | ADSORPTION | lacO-LacI binding | ANION-EXCHANGE CHROMATOGRAPHY | plasmid DNA | affinity ligands | EXTRACTION | PRECIPITATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | REPRESSOR PROTEIN | SEPARATION | BINDING | Bacteria - chemistry | Isopropyl Thiogalactoside - chemistry | Bacterial Proteins - chemistry | Green Fluorescent Proteins - genetics | DNA, Superhelical - chemistry | Green Fluorescent Proteins - chemistry | Chromatography, Affinity - methods | Sepharose - analogs & derivatives | Repressor Proteins - chemistry | Reproducibility of Results | Bacterial Proteins - genetics | Freeze Drying | Histidine - genetics | Lac Repressors | Repressor Proteins - genetics | Recombinant Fusion Proteins - chemistry | Escherichia coli - chemistry | Ribonuclease, Pancreatic - chemistry | Bacteria - genetics | Plasmids - isolation & purification | DNA, Superhelical - isolation & purification | Escherichia coli Proteins | Escherichia coli - genetics | Sepharose - chemistry | Plasmids - chemistry | Recombinant Fusion Proteins - genetics | Aspartic Acid - analogs & derivatives | Aspartic Acid - chemistry | Histidine - chemistry | Ribonucleic acid--RNA | Bacterial proteins | Genomics | Deoxyribonucleic acid--DNA | Chromatography | Cells | Index Medicus
Journal Article
Microbial Cell Factories, ISSN 1475-2859, 07/2009, Volume 8, Issue 1, pp. 35 - 35
Background: The optimisation and scale-up of process conditions leading to high yields of recombinant proteins is an enduring bottleneck in the post-genomic... 
SYSTEM | METHANOL | GLYCEROL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FERMENTATION | MEMBRANE-PROTEIN | OPTIMIZATION | SORBITOL | EXPERIMENTAL-DESIGN | EXPRESSION | MIXED FEEDS | Cell culture | Usage | Yeast fungi | Genetic aspects | Research | Management | Recombinant proteins | Production processes
Journal Article
Visual Cognition, ISSN 1350-6285, 07/2018, Volume 26, Issue 6, pp. 442 - 449
Marriages between White men and Asian women are over twice as frequent as those between White women and Asian men. Recent research has proposed that this... 
facial attractiveness | Sexual dimorphism | masculinity | INTERRACIAL MARRIAGE | MALE FACIAL ATTRACTIVENESS | INTERMARRIAGE | WOMENS MATE PREFERENCES | PATTERNS | PERCEIVED ATTRACTIVENESS | PSYCHOLOGY, EXPERIMENTAL | SYMMETRY | DEVELOPMENTAL STABILITY | HEALTH | SELECTION | Women | Attraction | Femininity | Dimorphism | Attorneys | Whites
Journal Article
Behavioral Sciences & the Law, ISSN 0735-3936, 07/2016, Volume 34, Issue 4, pp. 477 - 494
Journal Article
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