Biophysical Journal, ISSN 0006-3495, 02/2017, Volume 112, Issue 3, pp. 394a - 395a
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 01/2016, Volume 23, Issue 1, pp. 81 - 90
Broadly neutralizing antibodies (bNAbs) against HIV-1 Env V1V2 arise in multiple donors. However, atomic-level interactions had previously been determined only...
SITE | REPERTOIRE | POTENT NEUTRALIZATION | RECOGNITION | HIV-1-NEUTRALIZING ANTIBODIES | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENVELOPE PROTEIN | IMMUNOGEN DESIGN | MATURATION | CELL BIOLOGY | TRIMER | BIOPHYSICS | Cell Line | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | AIDS Vaccines - immunology | Models, Molecular | Crystallography, X-Ray | HIV Antibodies - chemistry | Antibodies, Neutralizing - immunology | HIV-1 - immunology | HIV Antibodies - immunology | HIV-1 - chemistry | Antibodies, Neutralizing - chemistry | Protein Binding | Protein Conformation | env Gene Products, Human Immunodeficiency Virus - chemistry | Prevention | Development and progression | Care and treatment | Research | HIV infection | Immunoglobulins | Immunology | Vaccines | Human immunodeficiency virus--HIV
SITE | REPERTOIRE | POTENT NEUTRALIZATION | RECOGNITION | HIV-1-NEUTRALIZING ANTIBODIES | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENVELOPE PROTEIN | IMMUNOGEN DESIGN | MATURATION | CELL BIOLOGY | TRIMER | BIOPHYSICS | Cell Line | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | AIDS Vaccines - immunology | Models, Molecular | Crystallography, X-Ray | HIV Antibodies - chemistry | Antibodies, Neutralizing - immunology | HIV-1 - immunology | HIV Antibodies - immunology | HIV-1 - chemistry | Antibodies, Neutralizing - chemistry | Protein Binding | Protein Conformation | env Gene Products, Human Immunodeficiency Virus - chemistry | Prevention | Development and progression | Care and treatment | Research | HIV infection | Immunoglobulins | Immunology | Vaccines | Human immunodeficiency virus--HIV
Journal Article
Structure, ISSN 0969-2126, 08/2016, Volume 24, Issue 8, pp. 1346 - 1357
Antibody somatic hypermutation (SHM) and affinity maturation enhance antigen recognition by modifying antibody paratope structure to improve its...
PROTEIN DYNAMICS | DESIGN | EVOLUTION | BIOPHYSICS | RECOGNITION | AFFINITY MATURATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FRAMEWORK | BINDING-SITE | DIVERSITY | FAMILY | CELL BIOLOGY | Viral antibodies | Antibodies | HIV (Viruses) | Mass spectrometry | Antigenic determinants | Crystals | Structure
PROTEIN DYNAMICS | DESIGN | EVOLUTION | BIOPHYSICS | RECOGNITION | AFFINITY MATURATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FRAMEWORK | BINDING-SITE | DIVERSITY | FAMILY | CELL BIOLOGY | Viral antibodies | Antibodies | HIV (Viruses) | Mass spectrometry | Antigenic determinants | Crystals | Structure
Journal Article
Biochemistry, ISSN 0006-2960, 04/2016, Volume 55, Issue 15, pp. 2197 - 2213
Antibody–antigen interactions are governed by recognition of specific residues and structural complementarity between the antigen epitope and antibody...
HIV-1 GP120 | NEUTRALIZING ANTIBODIES | HEMAGGLUTININ-STEM | CD4 BINDING-SITE | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GP120 ENVELOPE GLYCOPROTEIN | X-RAY | SURFACE GLYCOPROTEIN | HUMAN-IMMUNODEFICIENCY-VIRUS | HUMAN MONOCLONAL-ANTIBODIES | HIV Antibodies - metabolism | Amino Acid Sequence | Epitopes - metabolism | Humans | Models, Molecular | Crystallography, X-Ray | HIV Antibodies - chemistry | Antigen-Antibody Reactions | HIV Envelope Protein gp120 - immunology | HIV-1 - immunology | Antigen-Antibody Complex - chemistry | CD4 Antigens - chemistry | HEK293 Cells | Protein Binding | Protein Conformation | Epitopes - chemistry | Molecular Docking Simulation | HIV Envelope Protein gp120 - chemistry | Binding Sites, Antibody | CD4 Antigens - metabolism | Glycoproteins | Biochemistry | Chemical properties | Research | Antigenic determinants
HIV-1 GP120 | NEUTRALIZING ANTIBODIES | HEMAGGLUTININ-STEM | CD4 BINDING-SITE | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GP120 ENVELOPE GLYCOPROTEIN | X-RAY | SURFACE GLYCOPROTEIN | HUMAN-IMMUNODEFICIENCY-VIRUS | HUMAN MONOCLONAL-ANTIBODIES | HIV Antibodies - metabolism | Amino Acid Sequence | Epitopes - metabolism | Humans | Models, Molecular | Crystallography, X-Ray | HIV Antibodies - chemistry | Antigen-Antibody Reactions | HIV Envelope Protein gp120 - immunology | HIV-1 - immunology | Antigen-Antibody Complex - chemistry | CD4 Antigens - chemistry | HEK293 Cells | Protein Binding | Protein Conformation | Epitopes - chemistry | Molecular Docking Simulation | HIV Envelope Protein gp120 - chemistry | Binding Sites, Antibody | CD4 Antigens - metabolism | Glycoproteins | Biochemistry | Chemical properties | Research | Antigenic determinants
Journal Article
Journal of Virology, ISSN 0022-538X, 10/2013, Volume 87, Issue 19, pp. 10855 - 10873
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley...
X-RAY SOLUTION | HTLV-III | BIOLOGICAL MACROMOLECULES | VIROLOGY | SMALL-ANGLE SCATTERING | N-LINKED GLYCAN | ENVELOPE GLYCOPROTEIN | INNER DOMAIN | HYDROGEN/DEUTERIUM EXCHANGE | HUMAN-IMMUNODEFICIENCY-VIRUS | HUMAN MONOCLONAL-ANTIBODIES | Antibodies, Neutralizing | Surface Plasmon Resonance | Antigens, Viral - metabolism | Humans | Scattering, Small Angle | Glycosylation | HIV Envelope Protein gp120 - metabolism | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | Antigens, Viral - immunology | Deuterium Exchange Measurement | HIV Antibodies - immunology | Drug Design | AIDS Vaccines | Protein Conformation | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | HIV Envelope Protein gp120 - chemistry | CD4 Antigens - metabolism | Structure and Assembly
X-RAY SOLUTION | HTLV-III | BIOLOGICAL MACROMOLECULES | VIROLOGY | SMALL-ANGLE SCATTERING | N-LINKED GLYCAN | ENVELOPE GLYCOPROTEIN | INNER DOMAIN | HYDROGEN/DEUTERIUM EXCHANGE | HUMAN-IMMUNODEFICIENCY-VIRUS | HUMAN MONOCLONAL-ANTIBODIES | Antibodies, Neutralizing | Surface Plasmon Resonance | Antigens, Viral - metabolism | Humans | Scattering, Small Angle | Glycosylation | HIV Envelope Protein gp120 - metabolism | Epitopes - immunology | HIV Envelope Protein gp120 - immunology | Antigens, Viral - immunology | Deuterium Exchange Measurement | HIV Antibodies - immunology | Drug Design | AIDS Vaccines | Protein Conformation | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | HIV Envelope Protein gp120 - chemistry | CD4 Antigens - metabolism | Structure and Assembly
Journal Article
Journal of Virology, ISSN 0022-538X, 07/2011, Volume 85, Issue 14, pp. 7095 - 7107
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley...
IMMUNIZATION | IMMUNOGENICITY | VIROLOGY | PARTIAL DELETION | VACCINE | IMMUNODEFICIENCY-VIRUS TYPE-1 | GP140 | BROAD | GP120 | ISOLATE | ELICITS NEUTRALIZING ANTIBODIES | Surface Plasmon Resonance | Cell Line | env Gene Products, Human Immunodeficiency Virus - immunology | Base Sequence | Humans | Protein Structure, Quaternary | Solubility | Protein Binding | env Gene Products, Human Immunodeficiency Virus - metabolism | Antibodies, Monoclonal - metabolism | DNA Primers | env Gene Products, Human Immunodeficiency Virus - chemistry | Vaccines and Antiviral Agents
IMMUNIZATION | IMMUNOGENICITY | VIROLOGY | PARTIAL DELETION | VACCINE | IMMUNODEFICIENCY-VIRUS TYPE-1 | GP140 | BROAD | GP120 | ISOLATE | ELICITS NEUTRALIZING ANTIBODIES | Surface Plasmon Resonance | Cell Line | env Gene Products, Human Immunodeficiency Virus - immunology | Base Sequence | Humans | Protein Structure, Quaternary | Solubility | Protein Binding | env Gene Products, Human Immunodeficiency Virus - metabolism | Antibodies, Monoclonal - metabolism | DNA Primers | env Gene Products, Human Immunodeficiency Virus - chemistry | Vaccines and Antiviral Agents
Journal Article
Structure, ISSN 0969-2126, 08/2016, Volume 24, Issue 8
Journal Article
Protein Expression and Purification, ISSN 1046-5928, 07/2013, Volume 90, Issue 1, pp. 34 - 39
Vaccinia virus (VV) has been used to express a variety of heterologous proteins, including HIV envelope (Env) glycoproteins. The Env protein is synthesized as...
HIV envelope protein | gp120 | Vaccinia virus expression | Surface plasmon resonance | Empigen BB | CELLS | NEUTRALIZING ANTIBODIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | ENVELOPE GLYCOPROTEIN | VACCINATION | CLADE-C | HUMAN-IMMUNODEFICIENCY-VIRUS | GP160 | IMMUNOGENICITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROTEIN EXPRESSION | INFECTION | HIV Envelope Protein gp120 - genetics | Recombinant Proteins - metabolism | Detergents - chemistry | Vaccinia virus - metabolism | Electrophoresis, Polyacrylamide Gel | Organic Chemicals - chemistry | Recombinant Proteins - genetics | HIV Envelope Protein gp120 - metabolism | Protein Precursors - metabolism | Recombinant Proteins - isolation & purification | HIV Envelope Protein gp120 - isolation & purification | Chromatography, Gel | HIV Envelope Protein gp160 - metabolism | HIV (Viruses) | Vaccinia
HIV envelope protein | gp120 | Vaccinia virus expression | Surface plasmon resonance | Empigen BB | CELLS | NEUTRALIZING ANTIBODIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | ENVELOPE GLYCOPROTEIN | VACCINATION | CLADE-C | HUMAN-IMMUNODEFICIENCY-VIRUS | GP160 | IMMUNOGENICITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROTEIN EXPRESSION | INFECTION | HIV Envelope Protein gp120 - genetics | Recombinant Proteins - metabolism | Detergents - chemistry | Vaccinia virus - metabolism | Electrophoresis, Polyacrylamide Gel | Organic Chemicals - chemistry | Recombinant Proteins - genetics | HIV Envelope Protein gp120 - metabolism | Protein Precursors - metabolism | Recombinant Proteins - isolation & purification | HIV Envelope Protein gp120 - isolation & purification | Chromatography, Gel | HIV Envelope Protein gp160 - metabolism | HIV (Viruses) | Vaccinia
Journal Article
01/2013, ISBN 1321352123
Due to the impressive diversity of human immunodeficiency virus type 1 (HIV-1), control of the HIV-1 pandemic will likely depend on the design of a vaccine...
Immunology | Biochemistry | Virology
Immunology | Biochemistry | Virology
Dissertation
01/2013, ISBN 1321352123, Volume 76, Issue 3
Due to the impressive diversity of human immunodeficiency virus type 1 (HIV-1), control of the HIV-1 pandemic will likely depend on the design of a vaccine...
Book Chapter
Immunological Reviews, ISSN 0105-2896, 02/1997, Volume 155, Issue 1, pp. 29 - 40
Natural killer (NK) cells of inbred mice reject allogeneic bone‐marrow cells, and NK cells of F1 hybrid mice can reject parental bone‐marrow cells (hybrid...
INBRED MOUSE STRAINS | CLASS-I MHC | HYBRID RESISTANCE | LY-49 MULTIGENE FAMILY | NK CELLS | GENE | IMMUNOLOGY | EXPRESSION | HISTOCOMPATIBILITY ANTIGENS | TRANSGENIC MICE | MOLECULES | Bone Marrow Transplantation - immunology | Animals | Lymphocyte Activation | Isoantigens - immunology | Killer Cells, Natural - immunology | T-Lymphocytes - immunology | Mice | Graft Rejection - immunology | Cytotoxicity, Immunologic - immunology
INBRED MOUSE STRAINS | CLASS-I MHC | HYBRID RESISTANCE | LY-49 MULTIGENE FAMILY | NK CELLS | GENE | IMMUNOLOGY | EXPRESSION | HISTOCOMPATIBILITY ANTIGENS | TRANSGENIC MICE | MOLECULES | Bone Marrow Transplantation - immunology | Animals | Lymphocyte Activation | Isoantigens - immunology | Killer Cells, Natural - immunology | T-Lymphocytes - immunology | Mice | Graft Rejection - immunology | Cytotoxicity, Immunologic - immunology
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 12/1997, Volume 3, Issue 6, pp. 294 - 303
T cells present in bone marrow cell (BMC) grafts promote engraftment in histoincompatible hosts, but they or other T cells may also initiate lethal...
Graft facilitating T cells | Neonatal tolerance | Natural killer cells | Hybrid resistance | Cell Separation | Mice, Inbred C57BL | Thymus Gland - cytology | Immune Tolerance | Radiation Chimera | Mice, SCID | Graft vs Host Disease - immunology | Bone Marrow Transplantation - immunology | H-2 Antigens - immunology | Animals | Flow Cytometry | Bone Marrow Cells - immunology | Killer Cells, Natural - immunology | Mice, Inbred CBA | T-Lymphocytes - immunology | Thymus Gland - immunology | H-2 Antigens - analysis | Mice | Mice, Inbred BALB C | Graft Rejection - immunology
Graft facilitating T cells | Neonatal tolerance | Natural killer cells | Hybrid resistance | Cell Separation | Mice, Inbred C57BL | Thymus Gland - cytology | Immune Tolerance | Radiation Chimera | Mice, SCID | Graft vs Host Disease - immunology | Bone Marrow Transplantation - immunology | H-2 Antigens - immunology | Animals | Flow Cytometry | Bone Marrow Cells - immunology | Killer Cells, Natural - immunology | Mice, Inbred CBA | T-Lymphocytes - immunology | Thymus Gland - immunology | H-2 Antigens - analysis | Mice | Mice, Inbred BALB C | Graft Rejection - immunology
Journal Article
1917, 748
eBook
4/2003, Volume 22, Issue 1, 9
Book Review
1826, 45
Dedication to the Rev. Thaddeus Mason Harris (p. iii) signed: Daniel Davenport, Dorchester, January 1, 1826. Davenport was the sexton of the First Church in...
Medicine | Early Republic | Biography | Epitaphs
Medicine | Early Republic | Biography | Epitaphs
Book
BJS Open, ISSN 2474-9842, 06/2019, Volume 3, Issue 3, pp. 403 - 414
Background End colostomy rates following colorectal resection vary across institutions in high‐income settings, being influenced by patient, disease, surgeon...
Surgical outcomes | Medical research | Mortality | Colorectal cancer | Laparoscopy | Patients | Quality of life | Studies | Ethics | Ostomy | Hospitals | Collaboration | Surgeons | Colorectal surgery
Surgical outcomes | Medical research | Mortality | Colorectal cancer | Laparoscopy | Patients | Quality of life | Studies | Ethics | Ostomy | Hospitals | Collaboration | Surgeons | Colorectal surgery
Journal Article
Health Care Financing Review, ISSN 0195-8631, 1999, Volume 21, Issue 1, pp. 123 - 128
Data from the Medicare Current Beneficiary Survey Cost and Use Files for 1992-1996 were used to describe the osteoporosis and hip fracture burden for the...
HEALTH POLICY & SERVICES | HEALTH CARE SCIENCES & SERVICES | Ethnic Groups - statistics & numerical data | United States - epidemiology | Health Surveys | Humans | Aged, 80 and over | Female | Male | Aged | Medicare - utilization | Hip Fractures - epidemiology | Health Services Research | Osteoporosis - epidemiology | Hip joint | Aging | Physiological aspects | Osteoporosis | Fractures | Risk factors | Statistical data | Demographics | Medicare | Beneficiaries | Polls & surveys
HEALTH POLICY & SERVICES | HEALTH CARE SCIENCES & SERVICES | Ethnic Groups - statistics & numerical data | United States - epidemiology | Health Surveys | Humans | Aged, 80 and over | Female | Male | Aged | Medicare - utilization | Hip Fractures - epidemiology | Health Services Research | Osteoporosis - epidemiology | Hip joint | Aging | Physiological aspects | Osteoporosis | Fractures | Risk factors | Statistical data | Demographics | Medicare | Beneficiaries | Polls & surveys
Journal Article
1992, ISBN 0195073932, xvii, 414
chemistry | Stomach | Secretion | Gastroenterology | physiology | Gastric | Digestion | Research | History | Gastric Acid
Book