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Science, ISSN 0036-8075, 3/2006, Volume 311, Issue 5767, pp. 1563 - 1564
Natural circular proteins found in bacteria, plants, and mammals show antimicrobial activity and exceptional stability, making them ideal templates for... 
Proteins | Circles | Enzymes | Virulence | Viruses | Protein precursors | Cyclotides | Amino acids | Perspectives | H5N1 subtype influenza A virus | Virology | Bacteria | Biochemistry | Flowers & plants | Mammals | Pharmaceuticals
Journal Article
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 06/2019, Volume 58, Issue 23, pp. 7652 - 7656
Loops at protein–protein interfaces are a rich source of peptide leads that have high specificity and low toxicity. Although such peptides typically need to be... 
cyclic peptides | epitopes | peptides | molecular grafting | peptide therapeutics | DESIGN | NRF2 | INHIBITORS | CHEMISTRY, MULTIDISCIPLINARY | SCAFFOLD | Thermodynamics | Peptides | Therapeutics | Homeopathy | Materia medica and therapeutics | Antigenic determinants | Proteins | Anchors | Interfaces | Residues | Toxicity | Scaffolds
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 03/2019, Volume 123, Issue 9, pp. 1903 - 1912
Disulfide-rich peptides are a class of molecules for which NMR spectroscopy has been the primary tool for structural characterization. Here, we explore whether... 
REFINEMENT | MOLECULAR FRAGMENT REPLACEMENT | STRUCTURE GENERATION | X-RAY-STRUCTURE | FLEXIBILITY | ALGORITHM | CHEMISTRY, PHYSICAL | PROTEIN-STRUCTURE DETERMINATION | SIMULATIONS | NMR STRUCTURE DETERMINATION | PREDICTION
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2019, Volume 176, Issue 15, pp. 2750 - 2763
The heteromeric α4β2 nicotinic acetylcholine receptor (nAChR) is abundant in the human brain and is associated with a range of CNS disorders. This nAChR... 
Brain | Desensitization | Computer simulation | Channel gating | Molecular dynamics | Insecticides | Pharmacology | Chemical compounds | Domains | Receptors | Simulation | Acetylcholine receptors (nicotinic) | Transmembrane domains | Acetylcholine | Nicotine | Conformation
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 07/2016, Volume 2016, Issue 21, pp. 3457 - 3457
The cover picture shows a drawing of the marine cone snail Conus victoriae and the structure of a conotoxin found in its venom used for prey capture.... 
Journal Article
Peptide Science, ISSN 0006-3525, 11/2016, Volume 106, Issue 6, pp. 772 - 773
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 12/2007, Volume 72, Issue 6, pp. 1406 - 1410
Journal Article
Frontiers in plant science, ISSN 1664-462X, 2019, Volume 10, p. 645
The perennial leguminous herb (butterfly pea) has attracted significant interest based on its agricultural and medical applications, which range from use as a... 
Anthocyanin | Peptides | Technology application | peptides | medicinal plant | butelase | anthocyanins | forage crop | organic pesticide
Journal Article
Peptide Science, ISSN 0006-3525, 09/2013, Volume 100, Issue 5, pp. iii - v
Journal Article
Angewandte Chemie, ISSN 0044-8249, 06/2019, Volume 131, Issue 23, pp. 7734 - 7738
Loops at protein–protein interfaces are a rich source of peptide leads that have high specificity and low toxicity. Although such peptides typically need to be... 
Peptidtherapeutika | Epitope | Molekulares Aufpfropfen | Peptide | Cyclische Peptide | Peptides | Thermodynamics | Antigenic determinants | Proteins | Anchors | Interfaces | Residues | Toxicity | Scaffolds
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2003, Volume 278, Issue 48, pp. 48188 - 48196
The cyclotides are a recently discovered family of plant proteins that have the fascinating structural feature of a continuous cyclic backbone and, putatively,... 
3-DIMENSIONAL STRUCTURE | CHASSALIA-PARVIFOLIA | INHIBITORY MACROCYCLIC PEPTIDES | PLANT CYCLOTIDES | STRUCTURAL MOTIF | OLDENLANDIA-AFFINIS | MOMORDICA-COCHINCHINENSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DESIGN | SELECTIVE REDUCTION | MASS-SPECTROMETRY
Journal Article
Toxicon, ISSN 0041-0101, 02/2019, Volume 158, pp. S1 - S1
Journal Article
Methods in molecular biology (Clifton, N.J.), 2019, Volume 2012, pp. 29 - 41
Sortase A (SrtA) is an enzyme obtained from Staphylococcus aureus that catalyzes site-specific transpeptidation of surface proteins to the bacterial cell... 
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 05/2018, Volume 14, Issue 5, pp. 417 - 427
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 25, pp. 10127 - 10132
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2013, Volume 110, Issue 52, pp. 21183 - 21188
Cyclotides are plant peptides comprising a circular backbone and three conserved disulfide bonds that confer them with exceptional stability. They were... 
Receptors | Myometrium | Fractionation | HEK293 cells | Cyclotides | Ligands | Agonists | Pharmacology | Oxytocics | Oxytocin receptors | Peptide drugs | Uterotonic | Circular plant peptide | Peptide ligand design | Chemical pharmacology | chemical pharmacology | MECHANISM | peptide ligand design | MULTIDISCIPLINARY SCIENCES | peptide drugs | DRUG DESIGN | UTERINE CONTRACTILITY | KALATA B1 | HUMAN MYOMETRIUM | circular plant peptide | CYCLIC-CYSTINE-KNOT | VASOPRESSIN | uterotonic | ANTAGONISTS | BINDING | AGONIST | Oxytocics - pharmacology | Magnetic Resonance Spectroscopy | Receptors, G-Protein-Coupled - metabolism | Humans | Chromatography, High Pressure Liquid | Oxytocics - metabolism | Oxytocics - analysis | Oldenlandia - chemistry | Uterine Contraction - drug effects | Oligopeptides - biosynthesis | Cyclotides - analysis | Analysis of Variance | Collagen - drug effects | Cloning, Molecular | Drug Design | Cyclotides - metabolism | Female | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Cyclotides - pharmacology | Radioligand Assay | Cell receptors | Polysulfides | G proteins | Properties | Health aspects | Ligands (Biochemistry) | Molecules | Glycoproteins | Peptides | Cells | Index Medicus | Biological Sciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Natural Sciences
Journal Article