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1. Neuropsychological assessment
by Lezak, Muriel Deutsch
2004, 4th ed., ISBN 9780195111217, xiv, 1016
Psychological Tests | Neuropsychology | Neuropsychological tests | Neurophysiology
Book
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2. Full Text Production of stable bispecific IgG1 by controlled Fab-arm exchange
: Scalability from bench to large-scale manufacturing by application of standard approaches
by Gramer, Michael J and van den Bremer, Ewald TJ and van Kampen, Muriel D and Kundu, Amitava and Kopfmann, Peter and Etter, Eric and Stinehelfer, David and Long, Justin and Lannom, Tom and Noordergraaf, Esther H and Gerritsen, Jolanda and Labrijn, Aran F and Schuurman, Janine and van Berkel, Patrick HC and Parren, Paul WHI
mAbs, ISSN 1942-0862, 11/2013, Volume 5, Issue 6, pp. 962 - 973
The manufacturing of bispecific antibodies can be challenging for a variety of reasons. For example, protein expression problems, stability issues, or the use... 
controlled Fab-arm exchange | bispecific antibodies | large-scale manufacturing | cell culture | purification | scale up | Cell culture | Scale up | Purification | Controlled Fab-arm exchange | Bispecific antibodies | Large-scale manufacturing | MEDICINE, RESEARCH & EXPERIMENTAL | DESIGN | IMMUNOGLOBULIN | MONOCLONAL-ANTIBODY | INTERACTION STRENGTH | CANCER-THERAPY | MOLECULES | CHAIN | GROWTH-FACTOR RECEPTOR | MULTIPLE DISEASE MEDIATORS | Cricetinae | Cricetulus | Enzyme-Linked Immunosorbent Assay | Electrophoresis, Polyacrylamide Gel | Antibodies, Bispecific - biosynthesis | Antibodies, Bispecific - genetics | Point Mutation | Animals | Spectrometry, Mass, Electrospray Ionization | Bioreactors | Protein Engineering | Protein Stability | CHO Cells | Report
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3. Full Text Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response
by Amatangelo, Michael D and Quek, Lynn and Shih, Alan and Stein, Eytan M and Roshal, Mikhail and David, Muriel D and Marteyn, Benoit and Farnoud, Noushin Rahnamay and de Botton, Stephane and Bernard, Olivier A and Wu, Bin and Yen, Katharine E and Tallman, Martin S and Papaemmanuil, Elli and Penard-Lacronique, Virginie and Thakurta, Anjan and Vyas, Paresh and Levine, Ross L
Blood, ISSN 0006-4971, 08/2017, Volume 130, Issue 6, pp. 732 - 741
Recurrent mutations at R140 and R172 in isocitrate dehydrogenase 2 (IDH2) occur in many cancers, including similar to 12% of acute myeloid leukemia (AML). In... 
IDH2 MUTATIONS | STEM-CELLS | MUTANT IDH2 | ADULTS | PROGNOSTIC-SIGNIFICANCE | HEMATOLOGY | 2-HYDROXYGLUTARATE | Triazines - pharmacology | Neoplasm Recurrence, Local - metabolism | Triazines - therapeutic use | Leukemia, Myeloid, Acute - pathology | Gene Frequency | Humans | Leukemia, Myeloid, Acute - metabolism | Glutarates - antagonists & inhibitors | Neoplasm Recurrence, Local - drug therapy | Isocitrate Dehydrogenase - genetics | Male | Antineoplastic Agents - therapeutic use | Isocitrate Dehydrogenase - antagonists & inhibitors | Hematopoiesis - drug effects | Neoplasm Recurrence, Local - pathology | Aminopyridines - therapeutic use | Aminopyridines - pharmacology | Leukemia, Myeloid, Acute - drug therapy | Female | Neoplasm Recurrence, Local - genetics | Antineoplastic Agents - pharmacology | Glutarates - metabolism | Mutation | Leukemia, Myeloid, Acute - genetics | Clinical Trials and Observations
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4. Full Text Phosphorylation of ARHGAP19 by CDK1 and ROCK regulates its subcellular localization and function during mitosis
by Marceaux, Claire and Petit, Dominique and Bertoglio, Jacques and David, Muriel D
Journal of Cell Science, ISSN 0021-9533, 03/2018, Volume 131, Issue 5, pp. jcs208397 - jcs208397
ARHGAP19 is a hematopoietic-specific Rho GTPase-activating protein (RhoGAP) that acts through the RhoA/ROCK pathway to critically regulate cell elongation and... 
ARHGAP19 | CDK1 | ROCK | Mitosis | Rho GTPase | MGCRACGAP | SIGNALING PATHWAYS | EXCHANGE FACTOR | RHOA | CELL BIOLOGY | CYTOKINESIS | PHASE | ECT2 | EXPRESSION | BINDING | T-LYMPHOCYTES | Phosphorylation | Threonine | Serine | Prophase | Cell division | RhoA protein | Dephosphorylation | Kinases | Cytokinesis | Rho-associated kinase | Hemopoiesis | Proteins | 14-3-3 protein | GTPase-activating protein | Lymphocytes | Metaphase | Docking | Localization | Anaphase | Elongation | Binding sites | Guanosinetriphosphatase
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5. Full Text Le Maroc au présent
by Baudouin Dupret, Zakaria Rhani, Assia Boutaleb, Jean-Noël Ferrié
2015, ISBN 9954036202
Le Maroc est probablement l’un des pays d’Afrique du Nord et du Moyen Orient les plus étudiés par les sciences sociales et humaines. Motivée par la diversité... 
société | ville | politique | monde rural | rapports sociaux | femme | religion | sociologie | langues | anthropologie | changement social | économie | cultures | droit | territoire
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6. Full Text Quantitation of isocitrate dehydrogenase (IDH)-induced D and L enantiomers of 2-hydroxyglutaric acid in biological fluids by a fully validated liquid tandem mass spectrometry method, suitable for clinical applications
by Poinsignon, Vianney and Mercier, Lionel and Nakabayashi, Koïchi and David, Muriel D and Lalli, Alexandre and Penard- Lacronique, Virginie and Quivoron, Cyril and Saada, Véronique and De Botton, Stéphane and Broutin, Sophie and Paci, Angelo
Journal of Chromatography B, ISSN 1570-0232, 06/2016, Volume 1022, pp. 290 - 297
A recent update of the hallmarks of cancer includes metabolism with deregulating cellular energetics. Activating mutations in isocitrate dehydrogenase (IDH)... 
Biomarker | Endogenous compounds | Isocitrate dehydrogenase mutations | Oncometabolite | 2-Hydroxyglutaric acid | Liquid tandem mass spectrometry | CHEMISTRY, ANALYTICAL | IDH2 MUTATIONS | BIOCHEMICAL RESEARCH METHODS | DERIVATIZATION | BREAST | L-2-HYDROXYGLUTARATE ENANTIOMERS | D-2-HYDROXYGLUTARATE | Reproducibility of Results | Stereoisomerism | Humans | Leukemia, Myeloid, Acute - metabolism | Linear Models | Glutarates - blood | Biomarkers, Tumor - blood | Sensitivity and Specificity | Biomarkers, Tumor - metabolism | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - chemistry | Glutarates - metabolism | Biomarkers, Tumor - chemistry | Chromatography, Liquid - methods | Tandem Mass Spectrometry - methods | Enantiomers | Mass spectrometry | Methods | Enzymes | Deregulation | Diastereomers | Leukemia | Physiological aspects | Liquid chromatography | Mutations | Cellular | Ionization | Blood | Standards
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7. Non-English title
by Marchionea, Roberta and Daydea, David and Lenormanda, Jean-Luc and Corneta, Muriel
Journal of Medical Mycology, ISSN 1156-5233, 06/2015, Volume 25, Issue 2, pp. e103 - e104
Original Abstract: Introduction: L'identification de nouvelles cibles pour le developpement de therapies antifongiques efficaces et non toxiques pour les... 
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8. Grossesse après chirurgie bariatrique
by Favre, Lucie and Clarisse, Muriel and Pralong, François P and Suter, Michel and Fournier, Pierre and Baud, David
Revue Medicale Suisse, ISSN 1660-9379, 03/2016, Volume 12, Issue 511, pp. 606 - 610
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9. Full Text Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib
by Quek, Lynn and David, Muriel D and Kennedy, Alison and Metzner, Marlen and Amatangelo, Michael and Shih, Alan and Stoilova, Bilyana and Quivoron, Cyril and Heiblig, Maël and Willekens, Christophe and Saada, Véronique and Alsafadi, Samar and Vijayabaskar, M.S and Peniket, Andy and Bernard, Oliver A and Agresta, Sam and Yen, Katharine and MacBeth, Kyle and Stein, Eytan and Vassiliou, George S and Levine, Ross and De Botton, Stephane and Thakurta, Anjan and Penard-Lacronique, Virginie and Vyas, Paresh
Nature Medicine, ISSN 1078-8956, 08/2018, Volume 24, Issue 8, pp. 1167 - 1177
Mutations in the gene encoding isocitrate dehydrogenase 2 (IDH2) occur in several types of cancer, including acute myeloid leukemia (AML). In model systems,... 
MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | MUTANT IDH2 | PROGNOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE DOMAIN | CELL BIOLOGY | CELL LUNG-CANCER | EVOLUTION | RESISTANCE | CHRONIC LYMPHOCYTIC-LEUKEMIA | MUTATIONS | DIFFERENTIATION | Triazines - pharmacology | Triazines - therapeutic use | Leukemia, Myeloid, Acute - pathology | Neoplastic Stem Cells - drug effects | Humans | Immunophenotyping | Isocitrate Dehydrogenase - antagonists & inhibitors | Mutation - genetics | Neoplasm Recurrence, Local - pathology | Aminopyridines - therapeutic use | Neoplastic Stem Cells - metabolism | Cell Differentiation - drug effects | Hematopoiesis | Aminopyridines - pharmacology | Leukemia, Myeloid, Acute - drug therapy | Neoplastic Stem Cells - pathology | Isocitrate Dehydrogenase - metabolism | Clone Cells | Cohort Studies | Gene mutations | Cell differentiation | Research | Populations | Myeloid leukemia | Leukemia | Cloning | Differentiation (biology) | Patients | Hemopoiesis | Heterogeneity | Inhibitors | Evolution | Mutation | Acute myeloid leukemia | Isocitrate dehydrogenase | Cancer
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10. Full Text AG-221, a first-in-class therapy targeting acute myeloid leukemia harboring oncogenic IDH2 mutations
by Yen, Katharine and Travins, Jeremy and Wang, Fang and David, Muriel D and Artin, Erin and Straley, Kimberly and Padyana, Anil and Gross, Stefan and Delabarre, Byron and Tobin, Erica and Chen, Yue and Nagaraja, Raj and Choe, Sung and Jin, Lei and Konteatis, Zenon and Cianchetta, Giovanni and Saunders, Jeffrey O and Salituro, Francesco G and Quivoron, Cyril and Opolon, Paule and Bawa, Olivia and Saada, Véronique and Paci, Angelo and Broutin, Sophie and Bernard, Olivier A and De Botton, Stéphane and Marteyn, Benoît S and Pilichowska, Monika and Xu, Yingxia and Fang, Cheng and Jiang, Fan and Wei, Wentao and Jin, Shengfang and Silverman, Lee and Liu, Wei and Yang, Hua and Dang, Lenny and Dorsch, Marion and Penard-Lacronique, Virginie and Biller, Scott A and Michael Su, Shin-San
Cancer Discovery, ISSN 2159-8274, 05/2017, Volume 7, Issue 5, pp. 478 - 493
Somatic gain-of-function mutations in isocitrate dehydrogenases (IDH) 1 and 2 are found in multiple hematologic and solid tumors, leading to accumulation of... 
HYPERMETHYLATION | ONCOLOGY | MUTANT IDH2 | HEMATOPOIETIC STEM-CELLS | BLOCK | PROGNOSTIC-SIGNIFICANCE | INHIBITOR | ONCOMETABOLITE 2-HYDROXYGLUTARATE | SUFFICIENT | (R)-2-HYDROXYGLUTARATE | HISTONE | Xenograft Model Antitumor Assays | Triazines - pharmacology | Animals | Aminopyridines - pharmacology | Humans | Cell Line, Tumor | Isocitrate Dehydrogenase - genetics | Antineoplastic Agents - pharmacology | Mice | Mutation | Isocitrate Dehydrogenase - antagonists & inhibitors | Leukemia, Myeloid, Acute - genetics
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11. Full Text Vectorisation de molécules biologiques dans Candida albicans grâce au peptide de transduction MD-ZEBRA
by Marchione, Roberta and Daydé, David and Lenormand, Jean-Luc and Cornet, Muriel
Journal de Mycologie Médicale, ISSN 1156-5233, 06/2015, Volume 25, Issue 2, pp. e103 - e104
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12. Full Text Vectorisation de molecules biologiques dans Candida albicans grace au peptide de transduction MD-ZEBRA
by Marchione, Roberta and Dayde, David and Lenormand, Jean-Luc and Cornet, Muriel
Journal de Mycologie Medicale, ISSN 1156-5233, 06/2015, Volume 25, Issue 2, p. e103-e104
L'identification de nouvelles cibles pour le developpement de therapies antifongiques efficaces et non toxiques pour les cellules humaines reste un defi... 
Peptides
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13. Full Text The RhoGAP ARHGAP19 controls cytokinesis and chromosome segregation in T lymphocytes
by David, Muriel D and Petit, Dominique and Bertoglio, Jacques
Journal of Cell Science, ISSN 0021-9533, 01/2014, Volume 127, Issue 2, pp. 400 - 410
Small GTP-binding proteins of the Rho family orchestrate the cytoskeleton remodelling events required for cell division. Guanine nucleotide exchange factors... 
Vimentin | Rho GTPases | Rock | Cytokinesis | Lymphocytes | EXCHANGE FACTOR | HUMAN ECT2 | PHOSPHORYLATION | VIMENTIN FILAMENTS | CITRON KINASE | CLEAVAGE FURROW | CELL BIOLOGY | CONTRACTILE RING | CELL-DIVISION | RHOA ACTIVATION | INTERMEDIATE-FILAMENTS | Leukemia - pathology | Oligonucleotide Array Sequence Analysis | Vimentin - metabolism | Humans | Nocodazole - pharmacology | cdc42 GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Protein Transport - drug effects | GTPase-Activating Proteins - metabolism | Chromosome Segregation - drug effects | Mitosis - genetics | Cell Nucleus - metabolism | Myosin Type II - metabolism | T-Lymphocytes - metabolism | Time Factors | rho-Associated Kinases - metabolism | T-Lymphocytes - drug effects | Prometaphase - drug effects | Cell Membrane - metabolism | Phosphorylation - drug effects | Cell Membrane - drug effects | Leukemia - genetics | Protein-Serine-Threonine Kinases - metabolism | Cytokinesis - drug effects | Gene Expression Regulation, Leukemic - drug effects | Cell Shape - drug effects | Mitosis - drug effects | Signal Transduction - drug effects | T-Lymphocytes - cytology | Cell Line, Tumor | Cell Nucleus - drug effects | rac1 GTP-Binding Protein - metabolism
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14. Full Text Distinct structural features of Caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2α, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs
by Solomon, Samuel and Xu, Yaoxian and Wang, Bin and David, Muriel D and Schubert, Peter and Kennedy, Derek and Schrader, John W
Molecular and Cellular Biology, ISSN 0270-7306, 03/2007, Volume 27, Issue 6, pp. 2324 - 2342
Caprin-1 is a ubiquitously expressed, well-conserved cytoplasmic phosphoprotein that is needed for normal progression through the G(1)-S phase of the cell... 
RIBONUCLEOPROTEIN COMPLEXES | PKR | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | GROWTH | BINDING-PROTEIN | C-MYC | GTPASE-ACTIVATING PROTEIN | IDENTIFICATION | EXPRESSION | ENDORIBONUCLEASE G3BP | CELL BIOLOGY
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15. Full Text A 5-year intervention study on elimination of urogenital schistosomiasis in Zanzibar: Parasitological results of annual cross-sectional surveys
by Knopp, Stefanie and Ame, Shaali M and Person, Bobbie and Hattendorf, Jan and Rabone, Muriel and Juma, Saleh and Muhsin, Juma and Khamis, Iddi Simba and Hollenberg, Elizabeth and Mohammed, Khalfan A and Kabole, Fatma and Ali, Said M and Rollinson, David
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 05/2019, Volume 13, Issue 5, p. e0007268
Background The Zanzibar Elimination of Schistosomiasis Transmission (ZEST) project aimed to eliminate urogenital schistosomiasis as a public health problem... 
URINARY SCHISTOSOMIASIS | PRAZIQUANTEL | HEMATOBIUM | PEMBA-ISLAND | SCHOOLCHILDREN | MORBIDITY | PARASITOLOGY | TROPICAL MEDICINE | CHILDREN | Surveys | Schistosomiasis | Praziquantel | Public health | Intervention | Urine | Laboratories | Transmission | Objectives | Trade development | Systematic review | Infections | Museums | Surveying | Epidemiology | Eggs | Tropical diseases | Consortia | Confidence intervals | Students | Adults | Life sciences | Schools | Cross sections
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16. Muriel Rukeyser's Christmas Message for Teachers: The History and Text of "Christmas and the Image of the Teacher"
by Roessel, D and Pomar, J
RESOURCES FOR AMERICAN LITERARY STUDY, ISSN 0048-7384, 2015, Volume 38, pp. 171 - 171
In 1959, the poet Muriel Rukeyser was asked to write the Christmas issue of the Teacher's Letter, a trade newsletter for educators from Croft Educational... 
LITERATURE, AMERICAN
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17. Full Text Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers
by Popovici-Muller, Janeta and Lemieux, René M and Artin, Erin and Saunders, Jeffrey O and Salituro, Francesco G and Travins, Jeremy and Cianchetta, Giovanni and Cai, Zhenwei and Zhou, Ding and Cui, Dawei and Chen, Ping and Straley, Kimberly and Tobin, Erica and Wang, Fang and David, Muriel D and Penard-Lacronique, Virginie and Quivoron, Cyril and Saada, Véronique and de Botton, Stéphane and Gross, Stefan and Dang, Lenny and Yang, Hua and Utley, Luke and Chen, Yue and Kim, Hyeryun and Jin, Shengfang and Gu, Zhiwei and Yao, Gui and Luo, Zhiyong and Lv, Xiaobing and Fang, Cheng and Yan, Liping and Olaharski, Andrew and Silverman, Lee and Biller, Scott and Su, Shin-San M and Yen, Katharine
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 04/2018, Volume 9, Issue 4, pp. 300 - 305
Somatic point mutations at a key arginine residue (R132) within the active site of the metabolic enzyme isocitrate dehydrogenase 1 (IDH1) confer a novel gain... 
AG-120 | mutant IDH1 | ivosidenib | 2-hydroxyglutarate | isocitrate dehydrogenase | differentiation therapy | CHEMISTRY, MEDICINAL | IN-VIVO | MUTATION | ACUTE MYELOID-LEUKEMIA | CELL-DIFFERENTIATION | ENASIDENIB
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18. Full Text Epigenetic enhancement of antigen processing and presentation promotes immune recognition of tumors
by Setiadi, A. Francesca and Omilusik, Kyla and David, Muriel D and Seipp, Robyn P and Hartikainen, Jennifer and Gopaul, Rayshad and Choi, Kyung Bok and Jefferies, Wilfred A
Cancer Research, ISSN 0008-5472, 12/2008, Volume 68, Issue 23, pp. 9601 - 9607
Histone deacetylase inhibitors (HDACi) have been hailed as a powerful new class of anticancer drugs. The HDACi, trichostatin A (TSA), is thought to interfere... 
CANCER-CELLS | LUNG-CANCER | MELANOMA | THERAPY | ONCOLOGY | PATHWAY | CARCINOMAS | MECHANISMS | EXPRESSION | ESCAPE | TRICHOSTATIN | Melanoma, Experimental - drug therapy | Antigens, Neoplasm - biosynthesis | RNA Polymerase II - metabolism | ATP-Binding Cassette, Sub-Family B, Member 3 | RNA, Messenger - biosynthesis | T-Lymphocytes, Cytotoxic - drug effects | Melanoma, Experimental - immunology | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | Histocompatibility Antigens Class I - biosynthesis | Hydroxamic Acids - pharmacology | T-Lymphocytes, Cytotoxic - immunology | Promoter Regions, Genetic | Antigens, Neoplasm - immunology | Mice, Inbred C57BL | RNA, Messenger - genetics | Enzyme Inhibitors - pharmacology | Histocompatibility Antigens Class I - immunology | Antigen Presentation - genetics | ATP-Binding Cassette Transporters - biosynthesis | Membrane Transport Proteins - biosynthesis | Animals | Melanoma, Experimental - genetics | Epigenesis, Genetic - immunology | Cell Line, Tumor | Antigen Presentation - drug effects | Histone Deacetylase Inhibitors | Mice | Membrane Transport Proteins - immunology | ATP-Binding Cassette Sub-Family B Member 2
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