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FEBS Letters, ISSN 0014-5793, 2007, Volume 581, Issue 5, pp. 935 - 938
Sav1866 is a bacterial homolog of the human ABC transporter Mdr1 that causes multidrug resistance in cancer cells. We report the crystal structure of Sav1866... 
Mdr1 | Outward-facing conformation | Transport protein | Multidrug ABC transporter | ATP-bound state | AMP-PNP | ABC | TMD | multidrug resistance 1 gene | sodium dodecyl sulfate polyacrylamide electrophoresis | ATP binding cassette | SDS–PAGE | ADP | NBD | nucleotide binding domain | adenosine-5′-(β,γ-imido)triphosphate | transmembrane domain | adenosine diphosphate | adenosine triphosphate | ATP | transport protein | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | STATE | outward-facing conformation | MODEL | ATP-BINDING | ATPASES | CELL BIOLOGY | BIOPHYSICS | multidrug ABC transporter | HUMAN P-GLYCOPROTEIN | Recombinant Proteins - metabolism | Staphylococcus aureus - genetics | Drug Stability | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Adenosine Triphosphatases - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Crystallography, X-Ray | Recombinant Proteins - genetics | Adenylyl Imidodiphosphate - chemistry | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - genetics | Adenylyl Imidodiphosphate - metabolism | ATP-Binding Cassette Transporters - metabolism | Protein Binding | Adenosine Triphosphatases - chemistry | Bacterial Proteins - metabolism | Protein Conformation | Adenosine Triphosphatases - genetics | Staphylococcus aureus - metabolism | Staphylococcus aureus | Television broadcasting industry | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, 04/2018, Volume 115, Issue 14, p. 3640
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 09/2015, Volume 22, Issue 9, p. 686
  We present comprehensive maps at single-amino acid resolution of the residues stabilizing the human Gαi1 subunit in nucleotide- and receptor-bound states. We... 
Proteins | Amino acids | Mutation | Crystal structure
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 09/2015, Volume 22, Issue 9, pp. 686 - 694
Journal Article
Journal Article
Journal Article
Journal Article
BIOspektrum, ISSN 0947-0867, 11/2018, Volume 24, Issue 7, pp. 688 - 690
The mechanistic characterization of membrane proteins requires their stabilization in specific conformations. Camelid single-domain antibodies are particularly... 
Life Sciences | Biochemistry, general | Human Genetics | Life Sciences, general | Microbiology | Pharmacology/Toxicology | Proteins | Antibodies | Immunization | Membrane proteins
Journal Article
Journal Article
eLife, ISSN 2050-084X, 06/2019, Volume 8
One of the largest membrane protein families in eukaryotes are G protein-coupled receptors (GPCRs). GPCRs modulate cell physiology by activating diverse... 
Rhodopsin |