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Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. SCI-36 - SCI-36
Abstract Recent technological advances in the detection and characterization of cell free circulating tumor DNA (ctDNA) are providing new opportunities for... 
Journal Article
New England Journal of Medicine, ISSN 0028-4793, 2013, Volume 369, Issue 1, pp. 93 - 94
Journal Article
Pathology, ISSN 0031-3025, 2015, Volume 47, pp. S28 - S28
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2013, Volume 369, Issue 1, pp. 93 - 94
To the Editor: Dawson et al. (March 28 issue) 1 suggest that the detection of circulating tumor DNA in 58% of patients with metastatic breast cancer can be... 
CELLS | MEDICINE, GENERAL & INTERNAL | Biomarkers, Tumor - blood | Breast Neoplasms - secondary | DNA, Neoplasm - blood | Humans | Mucin-1 - blood | Neoplasm Metastasis - diagnosis | Female | Enumeration | Tumor cells | Breast cancer | Metastasis | Patients | Deoxyribonucleic acid--DNA | Metastases
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 497, Issue 7447, pp. 108 - 112
Cancers acquire resistance to systemic treatment as a result of clonal evolution and selection(1,2). Repeat biopsies to study genomic evolution as a result of... 
HETEROGENEITY | LUNG-CANCER | ACTIVATION | EVOLUTION | VARIANTS | AXL | MULTIDISCIPLINARY SCIENCES | TAMOXIFEN RESISTANCE | TUMOR-CELLS | MUTATIONS | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Genomics | Humans | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Ovarian Neoplasms - genetics | Neoplasms - genetics | DNA Mutational Analysis | Female | Antineoplastic Agents - pharmacology | DNA, Neoplasm - analysis | Ovarian Neoplasms - drug therapy | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Intercellular Signaling Peptides and Proteins - genetics | Breast Neoplasms - drug therapy | Genome, Human - genetics | Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - genetics | Drug Resistance, Neoplasm - genetics | Exome - genetics | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Breast Neoplasms - pathology | Retinoblastoma Protein - genetics | Plasma - chemistry | Alleles | Carcinoma, Non-Small-Cell Lung - drug therapy | DNA, Neoplasm - genetics | Neoplasms - pathology | Mediator Complex Subunit 1 - genetics | Drug Resistance, Neoplasm - drug effects | Evolution, Molecular | Antimitotic agents | Care and treatment | Physiological aspects | Dosage and administration | Genetic aspects | Research | Nucleotide sequencing | Drug resistance | Antineoplastic agents | DNA sequencing | Blood plasma | Cancer | Plasma | Biopsy | Breast cancer | Genomes | Mutation | Patients | Deoxyribonucleic acid--DNA | Tumors
Journal Article
Journal Article
Science Translational Medicine, ISSN 1946-6234, 05/2012, Volume 4, Issue 136, pp. 136ra68 - 136ra68
Plasma of cancer patients contains cell-free tumor DNA that carries information on tumor mutations and tumor burden. Individual mutations have been probed... 
CELL LUNG-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | DIGITAL PCR | THERAPY | GENOMES | QUANTIFICATION | RESISTANCE | CIRCULATING FREE DNA | CARCINOMA | SOMATIC MUTATIONS | BREAST | CELL BIOLOGY | DNA - genetics | Neoplasms - blood | Neoplasms - genetics | Humans | Neoplasms - diagnosis | High-Throughput Nucleotide Sequencing - methods | DNA - blood
Journal Article
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, ISSN 2157-1422, 04/2019, Volume 9, Issue 4
Journal Article
Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 13 Supplement, pp. 2937 - 2937
Journal Article
Leukemia & Lymphoma, ISSN 1042-8194, 01/2019, Volume 60, Issue 2, pp. 279 - 280
Journal Article
Nature, ISSN 0028-0836, 09/2015, Volume 525, Issue 7570, pp. 538 - 542
Bromodomain and extra terminal protein (BET) inhibitors are first-in-class targeted therapies that deliver a newtherapeutic opportunity by directly targeting... 
SELECTIVE-INHIBITION | ACCURATE | CHROMATIN | MECHANISM | MULTIDISCIPLINARY SCIENCES | ACUTE MYELOID-LEUKEMIA | DRUG-RESISTANCE | MUTATIONS | SEQUENCING DATA | CANCER | DISCOVERY | Chromatin - metabolism | Transcription, Genetic - drug effects | Clone Cells - drug effects | Neoplastic Stem Cells - drug effects | Epigenesis, Genetic | Humans | Leukemia, Myeloid, Acute - metabolism | Molecular Targeted Therapy | Neoplastic Stem Cells - metabolism | Leukemia, Myeloid, Acute - drug therapy | Neoplastic Stem Cells - pathology | Gene Expression Regulation, Neoplastic - drug effects | Hematopoietic Stem Cells - drug effects | Benzodiazepines - pharmacology | Leukemia, Myeloid, Acute - pathology | Cells, Cultured | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Hematopoietic Stem Cells - metabolism | Clone Cells - metabolism | beta Catenin - metabolism | Azepines - pharmacology | Transcription Factors - metabolism | Triazoles - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Clone Cells - pathology | Wnt Signaling Pathway - drug effects | Genes, myc - genetics | Hematopoietic Stem Cells - cytology | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mice | Drug Resistance, Neoplasm - drug effects | Leukemia, Myeloid, Acute - genetics | Proteins | Leukemia | Cloning | Cell cycle | Stem cells | Epigenetics | Apoptosis
Journal Article
Nature Communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, p. 8760
Circulating tumour DNA analysis can be used to track tumour burden and analyse cancer genomes non-invasively but the extent to which it represents metastatic... 
HETEROGENEITY | ACTIVATION | VARIANTS | PATHWAY | MULTIDISCIPLINARY SCIENCES | KINASE | ACQUIRED-RESISTANCE | SEQUENCING DATA | Carcinoma, Ductal, Breast - genetics | Receptors, Estrogen - metabolism | Humans | Receptor, ErbB-2 - metabolism | Clonal Evolution - genetics | Tamoxifen - administration & dosage | Case-Control Studies | Breast Neoplasms - metabolism | Brain Neoplasms - secondary | Carcinoma, Ductal, Breast - drug therapy | Neoplasm Metastasis | Lung Neoplasms - secondary | Adult | Carcinoma, Ductal, Breast - pathology | Female | Quinazolines - administration & dosage | Lapatinib | Liver Neoplasms - secondary | Carcinoma, Ductal, Breast - metabolism | Lung Neoplasms - genetics | Liver Neoplasms - genetics | Deoxycytidine - administration & dosage | Brain Neoplasms - genetics | Trastuzumab - administration & dosage | Breast Neoplasms - drug therapy | Sequence Analysis, DNA | Spinal Neoplasms - secondary | Breast Neoplasms - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Breast Neoplasms - pathology | Spinal Neoplasms - genetics | Bayes Theorem | DNA, Neoplasm - genetics | Mutation | Deoxycytidine - analogs & derivatives | Biological evolution | Breast cancer | Genomes | Metastasis | ErbB-2 protein | Patients | Metastases | Heterogeneity | Biopsy | Breast | Evolution | Deoxyribonucleic acid--DNA | Cancer | Tumors
Journal Article
Journal Article