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Journal Article
Development, ISSN 0950-1991, 09/2006, Volume 133, Issue 18, pp. 3695 - 3707
Both the Wnt/beta-catenin and Ihh signaling pathways play essential roles in crucial aspects of endochondral ossification: osteoblast differentiation,... 
β-catenin | Cartilage | Chondrocyte hypertrophy | Ihh | Endochondral bone | Joint | Wnt | Patched | Osteoblast differentiation | beta-catenin | PATHWAYS | OSTEOBLAST | joint | PROTEIN | cartilage | chondrocyte hypertrophy | endochondral bone | PROLIFERATION | DEVELOPMENTAL BIOLOGY | CHONDROCYTE DIFFERENTIATION | SKELETON | osteoblast differentiation | patched | INDIAN-HEDGEHOG | PTH/PTHRP RECEPTOR | GROWTH-PLATE | Immunohistochemistry | Cell Cycle - genetics | Chondrocytes - cytology | Osteogenesis - physiology | Cell Proliferation | Cell Survival - genetics | Apoptosis - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Wnt Proteins - metabolism | Hedgehog Proteins | Cell Differentiation - genetics | In Situ Hybridization | Gene Expression Regulation, Developmental | Bone and Bones - metabolism | Cartilage - cytology | Receptors, Cell Surface - physiology | Osteoblasts - cytology | Patched Receptors | Cell Differentiation - physiology | Cell Survival - physiology | Chondrocytes - metabolism | Joints - metabolism | Osteogenesis - genetics | Bone and Bones - cytology | Cartilage - embryology | Receptors, Cell Surface - metabolism | In Situ Nick-End Labeling - methods | Signal Transduction - genetics | Cartilage - metabolism | Wnt Proteins - chemistry | beta Catenin - metabolism | beta Catenin - genetics | Chondrocytes - enzymology | Animals | Joints - embryology | Joints - cytology | Cell Cycle - physiology | Signal Transduction - physiology | Mice | Apoptosis - physiology | Bone and Bones - embryology | Osteoblasts - metabolism | Patched-1 Receptor | Receptors, Cell Surface - genetics
Journal Article
Journal Article
Neuro-Oncology, ISSN 1522-8517, 05/2013, Volume 15, Issue 5, pp. 562 - 577
Glioblastoma multiforme (GBM), the most aggressive malignant primary brain tumor of the central nervous system, is characterized by a relentless disease... 
temozolomide | glioma | chemoresistance | P4HB | ER stress response | APOPTOSIS | SIGNALING PATHWAYS | PROTEIN DISULFIDE-ISOMERASE | DOWN-REGULATION | GRP78 | DEATH | AUTOPHAGY | CLINICAL NEUROLOGY | ONCOLOGY | HUMAN GLIOBLASTOMA CELLS | EXPRESSION | CYTOTOXICITY | RNA, Small Interfering - genetics | Apoptosis - drug effects | Protein Disulfide-Isomerases - metabolism | eIF-2 Kinase - metabolism | Humans | Neoplasm Recurrence, Local - drug therapy | Antineoplastic Agents, Alkylating - pharmacology | Drug Resistance, Neoplasm | Male | Protein Disulfide-Isomerases - antagonists & inhibitors | Brain Neoplasms - metabolism | Immunoenzyme Techniques | Glioma - metabolism | Procollagen-Proline Dioxygenase - metabolism | Flow Cytometry | Dacarbazine - pharmacology | Dacarbazine - analogs & derivatives | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Real-Time Polymerase Chain Reaction | eIF-2 Kinase - genetics | In Situ Nick-End Labeling | Endoplasmic Reticulum Stress - drug effects | Neoplasm Recurrence, Local - metabolism | RNA, Messenger - genetics | Brain Neoplasms - drug therapy | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Protein Disulfide-Isomerases - genetics | Animals | Procollagen-Proline Dioxygenase - genetics | Signal Transduction - drug effects | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Glioma - drug therapy | Basic and Translational Investigations
Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 3/2012, Volume 107, Issue 1, pp. 89 - 100
Temozolomide (TMZ) is the standard chemotherapeutic agent for human malignant glioma, but intrinsic or acquired chemoresistance represents a major obstacle to... 
Neurology | Medicine & Public Health | Glioma | Chemoresistance | Proteomics | Two-dimensional gel electrophoresis | Oncology | Temozolomide | CANCER CELLS | DEATH | CLINICAL NEUROLOGY | ADJUVANT TEMOZOLOMIDE | MALIGNANT GLIOMA | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | IN-VIVO | VIMENTIN EXPRESSION | UP-REGULATION | CATHEPSIN-D | MISMATCH REPAIR DEFICIENCY | In Situ Nick-End Labeling | Cell Proliferation | Humans | RNA, Messenger - genetics | Antineoplastic Agents, Alkylating - pharmacology | Drug Resistance, Neoplasm | Electrophoresis, Gel, Two-Dimensional | Wound Healing | Brain Neoplasms - drug therapy | Cell Adhesion | Blotting, Western | Brain Neoplasms - metabolism | Flow Cytometry | Cell Cycle | Dacarbazine - pharmacology | Dacarbazine - analogs & derivatives | Biomarkers, Tumor - metabolism | Glioblastoma - metabolism | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Glioblastoma - drug therapy | Real-Time Polymerase Chain Reaction | Apoptosis | Cell Movement | Chemotherapy | Gliomas | Analysis | Hydroxylases | Universities and colleges | Health aspects | Intermediate filament proteins | Cells | Cancer | Vimentin | temozolomide | Transcription | proteomics | Brain tumors | Cytology | Data processing | Glioma cells | Cell adhesion | Cell cycle | Cathepsin D | Procollagen-proline dioxygenase | glioblastoma cells | Cell migration | Tumors | Animal Tissue | Laboratory Investigation - Human
Journal Article
by Pattaro, Cristian and Teumer, Alexander and Gorski, Mathias and Chu, Auey Y and Li, Man and Mijatovic, Vladan and Garnaas, Maija and Tin, Aienne and Sorice, Rossella and Li, Yong and Taliun, Daniel and Olden, Matthias and Foster, Meredith and Yang, Qiong and Chen, Ming-Huei and Pers, Tune H and Johnson, Anew D and Ko, Yi-An and Fuchsberger, Christian and Tayo, Bamidele and Nalls, Michael and Feitosa, Mary F and Isaacs, Aaron and Dehghan, Abbas and d'Adamo, Pio and Adeyemo, Adebowale and Dieffenbach, Aida Karina and Zonderman, Alan B and Nolte, Ilja M and van der Most, Peter J and Wright, Alan F and Shuldiner, Alan R and Morrison, Alanna C and Hofman, Albert and Smith, Albert V and isbach, Albert W and Franke, Ane and Uitterlinden, Ane G and Metspalu, Anes and Tonjes, Anke and Lupo, Antonio and Robino, Antonietta and Johansson, Asa and Demirkan, Ayse and Kollerits, Barbara and Freedman, Barry I and Ponte, Belen and Oostra, Ben A and Paulweber, Bernhard and Kraemer, Bernhard K and Mitchell, Braxton D and Buckley, Brendan M and Peralta, Carmen A and Hayward, Caroline and Helmer, Catherine and Rotimi, Charles N and Shaffer, Christian M and Mueller, Christian and Sala, Cinzia and van Duijn, Cornelia M and Saint-Pierre, Aude and Ackermann, Daniel and Shriner, Daniel and Ruggiero, Daniela and Toniolo, Daniela and Lu, Yingchang and Cusi, Daniele and Czamara, Darina and Ellinghaus, David and Siscovick, David S and Ruderfer, Douglas and Gieger, Christian and Grallert, Harald and Rochtchina, Elena and Atkinson, Elizabeth J and Holliday, Elizabeth G and Boerwinkle, Eric and Salvi, Erika and Bottinger, Erwin P and Murgia, Federico and Rivadeneira, Fernando and Ernst, Florian and Kronenberg, Florian and Hu, Frank B and Navis, Gerjan J and Curhan, Gary C and Ehret, George B and Homuth, Georg and Coassin, Stefan and Thun, Gian-Ani and Pistis, Giorgio and Gambaro, Giovanni and Malerba, Giovanni and Montgomery, Grant W and Eiriksdottir, Gudny and Jacobs, Gunnar and Li, Guo and Wichmann, H-Erich and Campbell, Harry and Schmidt, Helena and ... and CARDIOGRAM and ICBP Consortium and AGEN Consortium and CHARGe-Heart Failure Grp and ECHOGen Consortium and CHARGe-Heart Failure Group and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet and Medicinsk genetik och genomik
Nature Communications, ISSN 2041-1723, 01/2016, Volume 7, Issue 1, p. 10023
Journal Article
The Lancet, ISSN 0140-6736, 12/2018, Volume 392, Issue 10162, pp. 2398 - 2412
Journal Article