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ANTICANCER RESEARCH, ISSN 0250-7005, 06/2018, Volume 38, Issue 6, pp. 3299 - 3307
Background: Prostate cancer presents the highest incidence rates among all cancers in men. Hapalindole H (Hap H), isolated from Fischerella muscicola (UTEX... 
CYTOKINES | mitochondria | AMBIGUINE | apoptosis | INDUCTION | hapalindole H | ONCOLOGY | inflammation | E-SELECTIN | GENES | cancer | Prostate | EXPRESSION | prostate
Journal Article
ANTICANCER RESEARCH, ISSN 0250-7005, 09/2010, Volume 30, Issue 9, pp. 3295 - 3300
Aim: Brucea javanica was studied to identify nuclear factor kappaB (NF-kB) inhibitors exhibiting reactive oxygen species (ROS) intracellular amplification.... 
CELLS | QUASSINOIDS | Brucea javanica | mitochondria | NF-kB | THALIDOMIDE | NFAT | SEEDS | ONCOLOGY | ROS | STRESS | cytotoxicity | CONSTITUENTS
Journal Article
Natural Product Research, ISSN 1478-6419, 09/2011, Volume 25, Issue 15, pp. 1412 - 1417
Journal Article
Journal of Natural Products, ISSN 0163-3864, 03/2019, Volume 82, Issue 3, pp. 657 - 679
Higher plants are well known for their value in affording clinically useful anticancer agents, with such compounds acting against cancer cells by a range of... 
CANCER-CELLS | NATURAL-PRODUCT | CHEMISTRY, MEDICINAL | CYTOTOXIC CARDIAC-GLYCOSIDES | GAMBOGIC ACID | CELL-CYCLE ARREST | SESQUITERPENE LACTONES | PLANT SCIENCES | IN-VITRO | PROSTATE-CANCER | ALPHA-MANGOSTIN | PHARMACOLOGY & PHARMACY | NF-KAPPA-B
Journal Article
Planta Medica, ISSN 0032-0943, 06/2015, Volume 81, Issue 11, pp. 933 - 933
Bioassay guided fractionation of the aril of M. fragrans yielded five phenolic compounds, one new acyclic bis phenylpropanoid (1) and four previously known... 
PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | PLANT SCIENCES
Conference Proceeding
JOURNAL OF NATURAL PRODUCTS, ISSN 0163-3864, 06/2019, Volume 82, Issue 6, pp. 1645 - 1655
Corchorusoside C (1), isolated from Streptocaulon juventas collected in Vietnam, was found to be nontoxic in a zebrafish (Danio rerio) model and to induce... 
CARDENOLIDE GLYCOSIDES | ACTIVATION | CHEMISTRY, MEDICINAL | RECEPTOR | PHARMACOLOGY & PHARMACY | FACTOR-KAPPA-B | ICAM-1 | DEATH | INHIBITORS | PROTEINS | CARDIAC-GLYCOSIDES | PLANT SCIENCES
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 08/2018, Volume 26, Issue 15, pp. 4452 - 4460
is a large genus of flowering plants, with several species, including the clove tree, used as important resources in the food and pharmaceutical industries. In... 
Cytotoxicity | NF-κB inhibition | Mitochondrial transmembrane potential inhibition | Pentacyclic triterpenoids | Syzygium corticosum | JPZKPTYPWSCQTN-LTFTTYLTSA-N | XUARCIYIVXVTAE-ZAPOICBTSA-N | VYKLRWGPNUVKNC-HNSJSBKASA-N | AOXTVVMIAYODJX-HCOAJINSSA-N | MDCGEAGEQVMWPE-SXGMEYSMSA-N | LXEQIOGTMDLLEC-UHFFFAOYSA-N | AQHKWALTXQHZKK-GLDUGTPFSA-N | ZOEYQETWCHEROV-DOMZBBRYSA-N | MKSFEZKHACTMCV-UHFFFAOYSA-N | WCGUUGGRBIKTOS-GPOJBZKASA-N | JJRYPZMXNLLZFH-URWSZGRFSA-N | QJSQOGJCHBXLAH-UHFFFAOYSA-N | KPQMCAKZRXOZLB-KOIHBYQTSA-N | QGJZLNKBHJESQX-FZFNOLFKSA-N | FVWJYYTZTCVBKE-ROUWMTJPSA-N | PFCVZKFJHRCLCC-PGOIBATFSA-N | KCDXJAYRVLXPFO-UHFFFAOYSA-N | QQLURXJDJDJYQV-UHFFFAOYSA-N | JWDDEDFQFOCWRN-LTQNRFLVSA-N | PSZDOEIIIJFCFE-OSQDELBUSA-N | RCOMNCICXWMEBP-BDCFQSRGSA-N | XEVQXKKKAVVSMW-WRWORJQWSA-N | VWWMSFMNICMFQB-AWEZNQCLSA-N | UXUVZTGGSMRNDQ-YMUSRRSASA-N | KWUXNWWMRBXQRC-BBBXVDCKSA-N | MIJYXULNPSFWEK-GTOFXWBISA-N | FRUITS | CHEMISTRY, MEDICINAL | NF-kappa B inhibition | CHEMICAL-SHIFTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | PREVENTION | CHEMISTRY, ORGANIC | SUPPRESSION | STRUCTURE ELUCIDATION | DISCOVERY | URSOLIC ACID | NMR | ANTIOXIDANT | CONSTITUENTS | Plant Leaves - chemistry | Plant Extracts - chemistry | NF-kappa B - antagonists & inhibitors | Antineoplastic Agents, Phytogenic - chemical synthesis | Triterpenes - pharmacology | Humans | Molecular Conformation | Antineoplastic Agents, Phytogenic - chemistry | NF-kappa B - metabolism | Structure-Activity Relationship | Membrane Potential, Mitochondrial - drug effects | HT29 Cells | Syzygium - chemistry | Triterpenes - chemistry | Plant Leaves - metabolism | Triterpenes - chemical synthesis | Cell Line, Tumor | Cell Proliferation - drug effects | Antineoplastic Agents, Phytogenic - pharmacology | Syzygium - metabolism | Index Medicus
Journal Article
Planta Medica, ISSN 0032-0943, 07/2014, Volume 80, Issue 10, pp. 796 - 796
The transcription factor NF-κB plays a significant role in cancer cell survival signaling. Targeting the NF-κB pathway promotes pro-apoptotic down-stream... 
PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | PLANT SCIENCES
Conference Proceeding
Planta Medica, ISSN 0032-0943, 07/2014, Volume 80, Issue 10, pp. 771 - 771
Hapindole H was evaluated for cytotoxic activity in three cancer cell lines; colon cancer HT-29 cells (ED 50 = 10.4µM), hormone dependent breast cancer MCF-7... 
PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | PLANT SCIENCES
Conference Proceeding
Planta Medica, ISSN 0032-0943, 07/2014, Volume 80, Issue 10, pp. 790 - 790
C. macrocarpa and C. madagascariensis and C. fragrans (Cannelaceae) are endemic medicinal plants of Madagascar widely prescribed for many ailments. Our... 
PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | PLANT SCIENCES
Conference Proceeding
Planta Medica, ISSN 0032-0943, 07/2014, Volume 80, Issue 10, pp. 812 - 812
In an effort to develop novel, specific and potent anti-cancer agents to treat breast cancer, six derivatives (A-F) were synthesized from the fungal... 
PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | PLANT SCIENCES
Conference Proceeding
Planta Medica, ISSN 0032-0943, 07/2014, Volume 80, Issue 10, pp. 789 - 790
A fruit-bearing tree from West Africa, Sacoglottis gabonensis , is used in cultural medicine to treat fever, diarrhea, infections, hypertension, and diabetes.... 
PHARMACOLOGY & PHARMACY | CHEMISTRY, MEDICINAL | PLANT SCIENCES
Conference Proceeding
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