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Frontiers in Neuroscience, ISSN 1662-453X, 02/2019, Volume 13
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Accumulating experimental evidence shows the... 
antagonists | neurodegeneration | agonists | tumor necrosis factor | Alzheimer’s disease | neuroprotection
Journal Article
Cell Cycle, ISSN 1538-4101, 09/2015, Volume 14, Issue 18, pp. 2985 - 2995
Previous research indicates that the GABA A ergic system is involved in the pathophysiology of the fragile X syndrome, a frequent form of inherited... 
targeted therapy | ganaxolone | receptor | fragile X syndrome | GABA | Fmr1 knockout mouse | FMRP mRNA target
Journal Article
2011, Neuromethods, ISBN 1607618974, Volume 48., xv, 732
Alzheimer Disease & Associated Disorders, ISSN 0893-0341, 11/2017
Dementia is a risk factor for unsafe driving. Therefore, an assessment strategy has recently been developed for the prediction of fitness to drive in patients... 
Journal Article
Tijdschrift voor Gerontologie en Geriatrie, ISSN 0167-9228, 06/2018, Volume 49, Issue 3, pp. 95 - 102
Journal Article
by Sims, Rebecca and Van Der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and EADI and GERAD PERADES and ARUKConsortium and CHARGE and ADGC and GERAD/PERADES, CHARGE, ADGC, EADI and ARUK Consortium and Stockholms universitet and Centrum för forskning om äldre och åldrande (ARC), (tills m KI) and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1373 - 1384
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2017
Abstract Alzheimer’s disease (AD) is strongly associated with microglia-induced neuroinflammation. Particularly, Aβ plaque-associated microglia take on an... 
Neurology | Internal Medicine
Journal Article
Tijdschrift voor gerontologie en geriatrie, ISSN 0167-9228, 06/2018, Volume 49, Issue 3, p. 95
In dementia, apathy and depression are often seen as one disorder because of the many overlapping symptoms. However, for therapy a correct differentiation is... 
Dementia - psychology | Humans | Male | Apathy | Psychiatric Status Rating Scales | Cognitive Dysfunction - epidemiology | Cognition - physiology | Cognitive Dysfunction - psychology | Female | Aged | Depressive Disorder - epidemiology | Cognition Disorders - epidemiology | Cognition Disorders - psychology
Journal Article
by Hollingworth, P and Harold, D and Sims, R and Gerrish, A and Lambert, J.C and Carrasquillo, M.M and Abraham, R and Hamshere, M.L and Pahwa, J.S and Moskvina, V and Dowzell, K and Jones, N and Stretton, A and Thomas, C and Richards, A and Ivanov, D and Widdowson, C and Chapman, J and Lovestone, S and Powell, J and Proitsi, P and Lupton, M.K and Brayne, C and Rubinsztein, D.C and Gill, M and Lawlor, B and Lynch, A and Brown, K.S and Passmore, P.A and Craig, D and McGuinness, B and Todd, S and Holmes, C and Mann, D and Smith, A.D and Beaumont, H and Warden, D and Wilcock, G and Love, S and Kehoe, P.G and Hooper, N.M and Vardy, E.R.L.C and Hardy, J and Mead, S and Fox, N.C and Rossor, M and Collinge, J and Maier, W and Jessen, F and Ruther, E and Schurmann, B and Heun, R and Kolsch, H and van den Bussche, H and Heuser, I and Kornhuber, J and Wiltfang, J and Dichgans, M and Frolich, L and Hampel, H and Gallacher, J and Hull, M and Rujescu, D and Giegling, I and Goate, A.M and Kauwe, J.S.K and Cruchaga, C and Nowotny, P and Morris, J.C and Mayo, K and Sleegers, K and Bettens, K and Engelborghs, S and de Deyn, P.P and Van Broeckhoven, C and Livingston, G and Bass, N.J and Gurling, H and McQuillin, A and Gwilliam, R and Deloukas, P and Al-Chalabi, A and Shaw, C.E and Tsolaki, M and Singleton, A.B and Guerreiro, R and Muhleisen, T. W and Nothen, M. M and Moebus, S and Jockel, K.H and Klopp, N and Wichmann, H. E and Pankratz, V.S and Sando, S.B and Aasly, J.O and Barcikowska, M and Wszolek, Z.K and Dickson, D.W and Graff-Radford, N.R. and others and Alzheimer's Dis Neuroimaging and EADI1 Consortium and CHARGE Consortium and Alzheimer's Disease Neuroimaging Initiative and EADI1 consortium and CHARGE consortium and the Alzheimer's Disease Neuroimaging Initiative
Nature Genetics, ISSN 1061-4036, 2011, Volume 43, Issue 5, pp. 429 - 435
Journal Article
by Deloukas, Panagiotis and Hamshere, Marian L and Lovestone, Simon and Mead, Simon and Nöthen, Markus M and Gerrish, Amy and O'Donovan, Michael and Hüll, Michael and Hardy, John and Hampel, Harald and Passmore, Peter A and Engelborghs, Sebastiaan and Abraham, Richard and Thomas, Charlene and Moskvina, Valentina and Brayne, Carol and Lawlor, Brian and Bass, Nicholas J and McQuillin, Andrew and Holmans, Peter A and Jones, Nicola and Pahwa, Jaspreet Singh and Morgan, Kevin and Klopp, Norman and Schürmann, Britta and Carrasquillo, Minerva M and Jessen, Frank and Tsolaki, Magda and McGuinness, Bernadette and Van Broeckhoven, Christine and De Deyn, Peter P and Cruchaga, Carlos and Mayo, Kevin and Wichmann, H-Erich and Brown, Kristelle S and Fox, Nick and Proitsi, Petroula and Mühleisen, Thomas W and Lupton, Michelle K and Lynch, Aoibhinn and Williams, Julie and Singleton, Andrew B and Moebus, Susanne and Dowzell, Kimberley and Livingston, Gill and Powell, John and Todd, Stephen and Wiltfang, Jens and Kornhuber, Johannes and Shaw, Christopher E and Pankratz, V Shane and Owen, Michael J and Holmes, Clive and Kehoe, Patrick G and Al-Chalabi, Ammar and Morgan, Angharad R and Heuser, Isabella and Williams, Amy and Mann, David and Gurling, Hugh and Kauwe, John S K and Goate, Alison M and Frölich, Lutz and Rubinsztein, David C and Love, Seth and Rossor, Martin and Rujescu, Dan and Hollingworth, Paul and Bettens, Karolien and Younkin, Steven G and Nowotny, Petra and Dichgans, Martin and Smith, A David and Collinge, John and van den Bussche, Hendrik and Gwilliam, Rhian and Guerreiro, Rita and Jöckel, Karl-Heinz and Sims, Rebecca and Morris, John C and Gill, Michael and Craig, David and Sleegers, Kristel and Harold, Denise and Stretton, Alexandra and Maier, Wolfgang
Nature Genetics, ISSN 1061-4036, 10/2009, Volume 41, Issue 10, pp. 1088 - 1093
Journal Article